-
1
-
-
26244432388
-
Cholesterol Treatment Trialists' (CTT) Collaborators. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
-
Baigent C., Keech A., Kearney P.M., et al. Cholesterol Treatment Trialists' (CTT) Collaborators. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 366 (2005) 1267-1278
-
(2005)
Lancet
, vol.366
, pp. 1267-1278
-
-
Baigent, C.1
Keech, A.2
Kearney, P.M.3
-
2
-
-
0035572718
-
Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
-
Takemoto M., and Liao J.K. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 21 (2001) 1712-1719
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1712-1719
-
-
Takemoto, M.1
Liao, J.K.2
-
3
-
-
34247884512
-
Pleiotropic effects of statins: stabilization of the vulnerable atherosclerotic plaque?
-
Akdim F., van Leuven S.I., Kastelein J.J.P., and Stroes E.S.G. Pleiotropic effects of statins: stabilization of the vulnerable atherosclerotic plaque?. Curr Pharm Des 13 (2007) 1003-1012
-
(2007)
Curr Pharm Des
, vol.13
, pp. 1003-1012
-
-
Akdim, F.1
van Leuven, S.I.2
Kastelein, J.J.P.3
Stroes, E.S.G.4
-
4
-
-
11344279659
-
C-reactive protein levels and outcomes after statin therapy
-
Ridker P.M., Cannon C.P., Morrow D., et al. C-reactive protein levels and outcomes after statin therapy. N Engl J Med 352 (2005) 20-28
-
(2005)
N Engl J Med
, vol.352
, pp. 20-28
-
-
Ridker, P.M.1
Cannon, C.P.2
Morrow, D.3
-
5
-
-
26844447541
-
Early and late benefits of high-dose atorvastatin in patients with acute coronary syndromes: results from the PROVE IT-TIMI 22 trial
-
Ray K.K., Cannon C.P., McCabe C.H., et al. Early and late benefits of high-dose atorvastatin in patients with acute coronary syndromes: results from the PROVE IT-TIMI 22 trial. J Am Coll Cardiol 46 (2005) 1405-1410
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 1405-1410
-
-
Ray, K.K.1
Cannon, C.P.2
McCabe, C.H.3
-
7
-
-
0032701646
-
Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
-
Podrez E.A., Schmidt D., Hoff H.F., and Hazen S.L. Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro. J Clin Invest 103 (1999) 1547-1560
-
(1999)
J Clin Invest
, vol.103
, pp. 1547-1560
-
-
Podrez, E.A.1
Schmidt, D.2
Hoff, H.F.3
Hazen, S.L.4
-
8
-
-
0345148809
-
Selective modification of apoB-100 in the oxidation of low density lipoproteins by myeloperoxidase in vitro
-
Yang C.Y., Gu Z.W., Yang M., et al. Selective modification of apoB-100 in the oxidation of low density lipoproteins by myeloperoxidase in vitro. J Lipid Res 40 (1999) 686-698
-
(1999)
J Lipid Res
, vol.40
, pp. 686-698
-
-
Yang, C.Y.1
Gu, Z.W.2
Yang, M.3
-
9
-
-
4344577056
-
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease
-
Zheng L., Nukuna B., Brennan M.L., et al. Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J Clin Invest 114 (2004) 529-541
-
(2004)
J Clin Invest
, vol.114
, pp. 529-541
-
-
Zheng, L.1
Nukuna, B.2
Brennan, M.L.3
-
10
-
-
4444292600
-
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport
-
Bergt C., Pennathur S., Fu X., et al. The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport. Proc Natl Acad Sci USA 101 (2004) 13032-13037
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13032-13037
-
-
Bergt, C.1
Pennathur, S.2
Fu, X.3
-
11
-
-
0037189377
-
Myeloperoxidase, a leukocyte-derived vascular NO oxidase
-
Eiserich J.P., Baldus S., Brennan M.L., et al. Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science 296 (2002) 2391-2394
-
(2002)
Science
, vol.296
, pp. 2391-2394
-
-
Eiserich, J.P.1
Baldus, S.2
Brennan, M.L.3
-
12
-
-
0028292033
-
Myeloperoxidase: a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
-
Daugherty A., Dunn J.L., Rateri D.L., and Heinecke J.W. Myeloperoxidase: a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions. J Clin Invest 94 (1994) 437-444
-
(1994)
J Clin Invest
, vol.94
, pp. 437-444
-
-
Daugherty, A.1
Dunn, J.L.2
Rateri, D.L.3
Heinecke, J.W.4
-
13
-
-
0029932445
-
Presence of hypochlorite-modified proteins in human atherosclerotic lesions
-
Hazell L.J., Arnold L., Flowers D., et al. Presence of hypochlorite-modified proteins in human atherosclerotic lesions. J Clin Invest 97 (1996) 1535-1544
-
(1996)
J Clin Invest
, vol.97
, pp. 1535-1544
-
-
Hazell, L.J.1
Arnold, L.2
Flowers, D.3
-
14
-
-
0035108136
-
Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
-
Sugiyama S., Okada Y., Sukhova G.K., et al. Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol 158 (2001) 879-891
-
(2001)
Am J Pathol
, vol.158
, pp. 879-891
-
-
Sugiyama, S.1
Okada, Y.2
Sukhova, G.K.3
-
15
-
-
3042812429
-
Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis
-
Sugiyama S., Kugiyama K., Aikawa M., et al. Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis. Arterioscler Thromb Vasc Biol 24 (2004) 1309-1314
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1309-1314
-
-
Sugiyama, S.1
Kugiyama, K.2
Aikawa, M.3
-
16
-
-
34347225913
-
Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study
-
Meuwese M.C., Stroes E.S., Hazen S.L., et al. Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol 50 (2007) 159-165
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 159-165
-
-
Meuwese, M.C.1
Stroes, E.S.2
Hazen, S.L.3
-
17
-
-
0035824162
-
Association between myeloperoxidase levels and risk of coronary artery disease
-
Zhang R., Brennan M.L., Fu X., et al. Association between myeloperoxidase levels and risk of coronary artery disease. JAMA 286 (2001) 2136-2142
-
(2001)
JAMA
, vol.286
, pp. 2136-2142
-
-
Zhang, R.1
Brennan, M.L.2
Fu, X.3
-
18
-
-
33646170866
-
Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase
-
Baldus S., Rudolph V., Roiss M., et al. Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase. Circulation 113 (2006) 1871-1878
-
(2006)
Circulation
, vol.113
, pp. 1871-1878
-
-
Baldus, S.1
Rudolph, V.2
Roiss, M.3
-
19
-
-
0142089171
-
Prognostic value of myeloperoxidase in patients with chest pain
-
Brennan M.L., Penn M.S., Van Lente F., et al. Prognostic value of myeloperoxidase in patients with chest pain. N Engl J Med 349 (2003) 1595-1604
-
(2003)
N Engl J Med
, vol.349
, pp. 1595-1604
-
-
Brennan, M.L.1
Penn, M.S.2
Van Lente, F.3
-
20
-
-
0141727730
-
Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes
-
Baldus S., Heeschen C., Meinertz T., et al. Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes. Circulation 108 (2003) 1440-1445
-
(2003)
Circulation
, vol.108
, pp. 1440-1445
-
-
Baldus, S.1
Heeschen, C.2
Meinertz, T.3
-
21
-
-
0033858562
-
Rationale design and baseline characteristics of a clinical trial comparing the effects of robust versus conventional cholesterol lowering and intima media thickness in patients with familial hypercholesterolemia. The atorvastatin versus simvastatin on atherosclerosis progression (ASAP) study
-
Smilde T.J., Trip M.D., Wollersheim H., et al. Rationale design and baseline characteristics of a clinical trial comparing the effects of robust versus conventional cholesterol lowering and intima media thickness in patients with familial hypercholesterolemia. The atorvastatin versus simvastatin on atherosclerosis progression (ASAP) study. Clin Drug Invest 20 (2001) 67-79
-
(2001)
Clin Drug Invest
, vol.20
, pp. 67-79
-
-
Smilde, T.J.1
Trip, M.D.2
Wollersheim, H.3
-
22
-
-
0035941786
-
Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolemia (ASAP); a prospective, randomised, double-blind trial
-
Smilde T.J., van Wissen S., Wollersheim H., et al. Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolemia (ASAP); a prospective, randomised, double-blind trial. Lancet 357 (2001) 577-581
-
(2001)
Lancet
, vol.357
, pp. 577-581
-
-
Smilde, T.J.1
van Wissen, S.2
Wollersheim, H.3
-
23
-
-
0036890370
-
Differential hs-CRP reduction in patients with familial hypercholesterolemia treated with aggressive or conventional statin therapy
-
Van Wissen S., Trip M.D., Smilde T.J., et al. Differential hs-CRP reduction in patients with familial hypercholesterolemia treated with aggressive or conventional statin therapy. Atherosclerosis 165 (2002) 361-366
-
(2002)
Atherosclerosis
, vol.165
, pp. 361-366
-
-
Van Wissen, S.1
Trip, M.D.2
Smilde, T.J.3
-
24
-
-
33745197790
-
Serum myeloperoxidase and mortality in maintenance hemodialysis patients
-
Kalantar-Zadeh K., Brennan M.L., and Hazen S.L. Serum myeloperoxidase and mortality in maintenance hemodialysis patients. Am J Kidney Dis 48 (2006) 59-68
-
(2006)
Am J Kidney Dis
, vol.48
, pp. 59-68
-
-
Kalantar-Zadeh, K.1
Brennan, M.L.2
Hazen, S.L.3
-
25
-
-
33748060845
-
Plasma myeloperoxidase levels in patients with chronic heart failure
-
Tang W.H., Brennan M.L., Philip K., et al. Plasma myeloperoxidase levels in patients with chronic heart failure. Am J Cardiol 98 (2006) 796-799
-
(2006)
Am J Cardiol
, vol.98
, pp. 796-799
-
-
Tang, W.H.1
Brennan, M.L.2
Philip, K.3
-
26
-
-
18044395737
-
Statins downregulate myeloperoxidase gene expression in macrophages
-
Kumar A.P., and Reynolds W.F. Statins downregulate myeloperoxidase gene expression in macrophages. Biochem Biophys Res Commun 331 (2005) 442-451
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 442-451
-
-
Kumar, A.P.1
Reynolds, W.F.2
-
27
-
-
33646841215
-
The effect of atorvastatin on serum myeloperoxidase and CRP levels in patients with acute coronary syndrome
-
Zhou T., Zhou S.H., Qi S.S., et al. The effect of atorvastatin on serum myeloperoxidase and CRP levels in patients with acute coronary syndrome. Clin Chim Acta 368 (2006) 168-172
-
(2006)
Clin Chim Acta
, vol.368
, pp. 168-172
-
-
Zhou, T.1
Zhou, S.H.2
Qi, S.S.3
-
28
-
-
0030803161
-
Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation
-
Hazen S.L., Crowley J.R., Mueller D.M., and Heinecke J.W. Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation. Free Radic Biol Med 23 (1997) 909-916
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 909-916
-
-
Hazen, S.L.1
Crowley, J.R.2
Mueller, D.M.3
Heinecke, J.W.4
-
29
-
-
5644262427
-
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species
-
Pennathur S., Bergt C., Shao B., et al. Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species. J Biol Chem 279 (2004) 42977-42983
-
(2004)
J Biol Chem
, vol.279
, pp. 42977-42983
-
-
Pennathur, S.1
Bergt, C.2
Shao, B.3
-
30
-
-
0043166521
-
Statins promote potent systemic antioxidant through specific inflammatory pathways
-
Shishehbor M.H., Brennan M.L., Aviles R.J., et al. Statins promote potent systemic antioxidant through specific inflammatory pathways. Circulation 108 (2003) 426-431
-
(2003)
Circulation
, vol.108
, pp. 426-431
-
-
Shishehbor, M.H.1
Brennan, M.L.2
Aviles, R.J.3
-
31
-
-
3042756855
-
Serum myeloperoxidase levels independently predict endothelial dysfunction in humans
-
Vita J.A., Brennan M.L., Gokce N., et al. Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. Circulation 110 (2004) 1134-1139
-
(2004)
Circulation
, vol.110
, pp. 1134-1139
-
-
Vita, J.A.1
Brennan, M.L.2
Gokce, N.3
-
32
-
-
33646919624
-
Active metabolite of atorvastatin inhibits membrane cholesterol domain formation by an antioxidant mechanism
-
Mason R.P., Walter M.F., Day C.A., and Jacob R.F. Active metabolite of atorvastatin inhibits membrane cholesterol domain formation by an antioxidant mechanism. J Biol Chem 281 (2006) 9337-9345
-
(2006)
J Biol Chem
, vol.281
, pp. 9337-9345
-
-
Mason, R.P.1
Walter, M.F.2
Day, C.A.3
Jacob, R.F.4
-
33
-
-
0036162113
-
Cellular antioxidant effects of atorvastatin in vitro and in vivo
-
Wassmann S., Laufs U., Müller K., et al. Cellular antioxidant effects of atorvastatin in vitro and in vivo. Arterioscler Thromb Vasc Biol 22 (2002) 300-305
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 300-305
-
-
Wassmann, S.1
Laufs, U.2
Müller, K.3
-
34
-
-
20344391164
-
Expression of human myeloperoxidase by macrophages promotes atherosclerosis in mice
-
McMillen T.S., Heinecke J.W., and LeBoeuf R.C. Expression of human myeloperoxidase by macrophages promotes atherosclerosis in mice. Circulation 111 (2005) 2798-2804
-
(2005)
Circulation
, vol.111
, pp. 2798-2804
-
-
McMillen, T.S.1
Heinecke, J.W.2
LeBoeuf, R.C.3
-
35
-
-
33646918054
-
Myeloperoxidase predicts progression of carotid stenosis in states of low high-density lipoprotein cholesterol
-
Exner M., Minar E., Mlekusch W., et al. Myeloperoxidase predicts progression of carotid stenosis in states of low high-density lipoprotein cholesterol. J Am Coll Cardiol 47 (2006) 2212-2218
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 2212-2218
-
-
Exner, M.1
Minar, E.2
Mlekusch, W.3
|