Minocycline as a therapeutic drug for methamphetamine use disorders

Japanese Journal of Neuropsychopharmacology

Volumn 28, Issue 1, 2008, Pages 19-22

  Hashimoto, Kenji ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Abused drug; Methamphetamine; Neurotoxicity; Positron emission tomography (PET); Psychosis

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ANTIBIOTIC AGENT; METHAMPHETAMINE; MINOCYCLINE;

ABNORMAL BEHAVIOR; DRUG DEPENDENCE; HUMAN; NEUROTOXICITY; PSYCHOSIS; REVIEW; SCHIZOPHRENIA;

ANIMALS; ANTI-BACTERIAL AGENTS; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; METHAMPHETAMINE; MINOCYCLINE; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; POSITRON-EMISSION TOMOGRAPHY; PSYCHOSES, SUBSTANCE-INDUCED; SCHIZOPHRENIA; SUBSTANCE-RELATED DISORDERS;

EID: 40949090661     PISSN: 13402544     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (41)

1. Buchert, R., Thomasius, R., White, F., Petersen, K., Nebeling, B., Obrocki, J., Schulze, O., Schmidt, U. and Clausen, M. (2004) A voxel-based PET investigation of the long-term effects of "Ecstasy" consumption on brain serotonin transporters. Am J Psychiatry, 161: 1181-1189.
2. Cowan, R. L. (2007) Neuroimaging research in human MDMA users: A review. Psychopharmacology, 189: 539-556.
3. Domercq, M. and Matute, C. (2004) Neuroprotection by tetracyclines. Trends Pharmacol Sci, 25: 609-612.
4. Fujita, Y., Ishima, T., Kunitachi, S., Hagiwara, H., Zhang, L., Iyo, M. and Hashimoto, K. (2008) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antibiotic drug minocycline. Prog Neuropsychopharmacol Biol Psychiatry, in press.
5. Fukami, G., Hashimoto, K., Koike, K., Okamura, N., Shimizu, E. and Iyo, M. (2004) Effect of antioxidant N-acetyl-L-cysteine on behavioral changes and neurotoxicity in rats after administration of methamphetamine. Brain Res, 1016: 90-95.
6. Japanese source
7. Hashimoto, K. (2007) Chapter 1: New research on methamphetamine abuse. In Toolaney, G. H. (Ed) New Research on Methamphetamine Abuse. Nova Publishers, pp 1-51.
8. 3H]6- nitro-quipazine-labelled 5-HT uptake sites in rat brain by MDMA. Fundam Clin Pharmacol, 4: 635-641.
9. 3H]6- nitroquipazine. Res Comm Subst Abuse, 13: 191-201.
10. Japanese source
11. Japanese source
12. Hashimoto, K., Okamura, N., Shimizu, E. and Iyo, M. (2004a) Glutamate hypothesis of schizophrenia and approach for possible therapeutic drugs. Curr Med Chem-CNS Agents, 4: 147-154.
13. Hashimoto, K., Tsukada, H., Nishiyama, S., Fukumoto, D., Kakiuchi, T., Shimizu, E. and Iyo, M. (2004b) Protective effects of N-acetyl-L-cysteine on the reduction of dopamine transporters in the striatum of monkeys treated with methamphetamine. Neuropsychopharmacology, 29: 2018-2023.
14. Hashimoto, K., Fujita, Y., Shimizu, E. and Iyo, M. (2005a) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol. Eur J Pharmacol, 519: 114-117.
15. Hashimoto, K., Shimizu, E. and Iyo, M. (2005b) Dysfunction of glia-neuron communication in pathophysiology of schizophrenia. Curr Psychiatry Rev, 1: 151-163.
16. Hashimoto, K., Fujita, Y., Ishima, T., Hagiwara, H. and Iyo, M. (2006) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of tropisetron: Role of α7 nicotinic receptors. Eur J Pharmacol, 553: 191-195.
17. Hashimoto, K., Fujita, Y., Ishima, T., Chaki, S. and Iyo, M. (2007a) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of glycine transporter-1 inhibitor NFPS and D-serine. Eur Neuropsychopharmacol, in press.
18. Hashimoto, K., Fujita, Y. and Iyo, M. (2007b) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: Role of sigma-1 receptors. Neuropsychopharmacology, 32: 514-521.
19. Hashimoto K, Tsukada H, Nishiyama S, Fukumoto, D., Kakiuchi, T. and Iyo, M. (2007c) Protective effects of minocycline on the reduction of dopamine transporters in the striatum after administration of methamphetamine: A positron emission tomography study in conscious monkeys. Biol Psychiatry, 61: 577-581.
20. Hashimoto, K., Ishima, T., Fujita, Y., Matsuo, M., Kobashi, T., Takahagi, M., Tsukada, H. and Iyo, M. (2008) Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective α7 nicotinic receptor agonist SSR180711. Biol Psychiatry, 63: 92-97.
21. Hashimoto, T., Hashimoto, K., Matsuzawa, D., Shimizu, E., Sekine, Y., Inada, T., Ozaki, N., Iwata, N., Harano, M., Komiyama, T., Yamada, M., Sora, I., Ujike, H. and Iyo, M. (2005) A functional glutathione S-transferase P1 gene polymorphism is associated with methamphetamine-induced psychosis in Japanese population. Am J Med Genet B Neuropsychiatr Genet, 135: 5-9.
22. Jordan, J., Fernandez-Gomez, F. J., Ramos, M., Ikuta, I., Aguirre, N. and Galindo, M. F. (2007) Minocycline and cytoprotection: Shedding new light on a shadowy controversy. Curr Drug Deliv, 4: 225-231.
23. Koizumi, H., Hashimoto, K., Kumakiri, C., Shimizu, E., Sekine, Y., Ozaki, N., Inada, T., Harano, M., Komiyama, T., Yamada, M., Sora, I., Ujike, H., Takei, N. and Iyo, M. (2004) Association between the glutathione S-transferase M1 gene deletion and female methamphetamine abusers. Am J Med Genet B Neuropsychiatr Genet, 126: 43-45.
24. LaVoie, M.J., Card, J. P. and Hastings, T. G. (2004) Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity. Exp Neurol, 187: 47-57.
25. Matsuzawa, D., Hashimoto, K., Miyatake, R., Shirayama, Y., Shimizu, E., Maeda, K., Suzuki, Y., Mashimo, Y., Sekine, Y., Inada, T., Ozaki, N., Iwata, N., Harano, M., Komiyama, T., Yamada, M., Sora, I., Ujike, H., Hata, A., Sawa, A. and Iyo, M. (2007) Identification of functional polymorphisms in the promoter region of the human PICK1 gene and their association with methamphetamine psychosis. Am J Psychiatry, 164: 1105-1114.
26. 11C]WIN-35,428. J Neurosci, 18: 8417-8422.
27. McCann, U. D., Szabo, Z., Scheffel, U., Dannals, R. F. and Ricaurte, G. A. (1998b) Positron emission tomographic evidence of toxic effect of MDMA ("ecstasy") on brain serotonin neurons in human beings. Lancet, 352: 1433-1437.
28. Miyaoka, T., Yasukawa, R., Yasuda, H., Hayashida, M., Inagaki, T. and Horiuchi, J. (2007a) Possible antipsychotic effects of minocycline in patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry, 31: 304-307, 2007.
29. Miyaoka, T., Yasukawa, R., Yasuda, H., Hayashida, M., Inagaki, T. and Horiuchi, J. (2007b) Minocycline as adjunctive therapy for schizophrenia. Clin Neuropharmacol, in press.
30. Mizoguchi, H., Takuma, K., Fukakusa, A., Ito, Y., Nakatani, A., Ibi, D., Kim, H.C. and Yamada, K. (2008) Improvement by minocycline of methamphetamine-induced impairment of recognition memory in mice. Psychopharmacology, 196: 233-241.
31. Ohgake, S., Hashimoto, K., Shimizu, E., Koizumi, H., Okamura, N., Koike, K., Matsuzawa, D., Sekine, Y., Inada, T., Ozaki, N., Iwata, N., Harano, M., Komiyama, T., Yamada, M., Sora, I., Ujike, H., Shirayama, Y. and Iyo, M. (2005) Functional polymorphism of the NQO2 gene is associated with methamphetamine psychosis. Addict Biol, 10: 145-148.
32. Orio, L., O'Shea, E., Sanchez, V., Pradillo, J. M., Escobedo, I., Camarero, J., Moro, M. A., Green, A. R. and Colado, M. I. (2004) 3,4-Methylenedioxymethamphetamine increases interleukin-1β levels and activates microglia in rat brain: Studies on the relationship with acute hyperthermia and 5-HT depletion. J Neurochem, 89: 1445-1453.
33. Reneman, L., Lavalaye, J., Schmand, B., de Wolff, F. A., van den Brink, W., den Heeten, G. J. and Booij, J. (2001) Cortical serotonin transporter density and verbal memory in individuals who stopped using MDMA. Arch Gen Psychiatry, 58: 901-906.
34. Sekine, Y., Iyo, M., Ouchi, Y., Matsunaga, T., Tsukada, H., Okada, H., Yoshikawa, E., Futatsubashi, M., Takei, N. and Mori, N. (2001) Methamphetamine-related psychotic symptoms and reduced brain dopamine transporters studied with PET. Am J Psychiatry, 158: 1206-1214.
35. Thomas, D. M., Walker, P. D., Benjamins, J. A., Geddes, T. J. and Kuhn, D. M. (2004) Methamphetamine neurotoxicity in dopamine nerve endings of the striatum is associated with microglial activation. J Pharmacol Exp Ther, 311: 1-7.
36. Japanese source
37. Volkow, N. D., Chang, L., Wang, G. J., Fowler, J. S., Leonido-Yee, M., Franceschi, D., Sedler, M. J., Gatley, S. J., Hitzemann, R., Ding, Y. S., Logan, J., Wong, C. and Miller, E. N. (2001) Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers. Am J Psychiatry, 158: 377-382.
38. Yong, V. W., Wells, J., Giuliani, F., Casha, S., Power, C. and Metz, L. M. (2004) The promise of minocycline in neurology. Lancet Neurol, 3: 744-751.
39. Zhang, L., Kitaichi, K., Fujimoto, Y., Nakayama, H., Shimizu, E., Iyo, M. and Hashimoto, K. (2006a) Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine. Prog Neuropharmacol Biol Psychiatry, 30: 1381-1393.
40. Zhang, L., Shirayama, Y., Shimizu, E., Iyo, M. and Hashimoto, K. (2006b) Protective effects of minocycline on 3,4-methylenedioxymethamphetamine-induced neurotoxicity in serotonergic and dopaminergic neurons of mouse brain. Eur J Pharmacol, 544: 1-9.
41. Zhang, L., Shirayama, Y., Iyo, M. and Hashimoto, K. (2007) Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine. Neuropsychopharmacology 32: 2001-2010.