-
1
-
-
0041671071
-
QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling
-
Ai X, Do AT, Lozynska O, Kusche-Gullberg M, Lindahl U, Emerson CP Jr. 2003. QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling. J Cell Biol 162:341-351.
-
(2003)
J Cell Biol
, vol.162
, pp. 341-351
-
-
Ai, X.1
Do, A.T.2
Lozynska, O.3
Kusche-Gullberg, M.4
Lindahl, U.5
Emerson Jr., C.P.6
-
2
-
-
0032526145
-
Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparin sulfate 2-sulfotransferase
-
Bullock SL, Fletcher JM, Beddington RS, Wilson VA. 1998. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparin sulfate 2-sulfotransferase. Genes Dev 12:1894-1906.
-
(1998)
Genes Dev
, vol.12
, pp. 1894-1906
-
-
Bullock, S.L.1
Fletcher, J.M.2
Beddington, R.S.3
Wilson, V.A.4
-
3
-
-
23944455883
-
A unique role for 6-O-sulfation modification in zebrafish vascular development
-
Chen E, Stringer SE, Rusch MA, Selleck SB, Ekker SC. 2005. A unique role for 6-O-sulfation modification in zebrafish vascular development. Dev Biol 284:364-376.
-
(2005)
Dev Biol
, vol.284
, pp. 364-376
-
-
Chen, E.1
Stringer, S.E.2
Rusch, M.A.3
Selleck, S.B.4
Ekker, S.C.5
-
4
-
-
0034019920
-
Expression of Cre recombinase in mouse oocytes: A means to study maternal effect genes
-
deVries WN, Binns LT, Fancher KS, Dean J, Moore R, Kemler R, Knowles BB. 2000. Expression of Cre recombinase in mouse oocytes: A means to study maternal effect genes. Genesis 26:110-112.
-
(2000)
Genesis
, vol.26
, pp. 110-112
-
-
deVries, W.N.1
Binns, L.T.2
Fancher, K.S.3
Dean, J.4
Moore, R.5
Kemler, R.6
Knowles, B.B.7
-
5
-
-
0035997376
-
Order out of chaos: Assembly of ligand binding sites in heparan sulfate
-
Esko JD, Selleck SB. 2002. Order out of chaos: assembly of ligand binding sites in heparan sulfate. Annu Rev Biochem 71:435-471.
-
(2002)
Annu Rev Biochem
, vol.71
, pp. 435-471
-
-
Esko, J.D.1
Selleck, S.B.2
-
6
-
-
0033979749
-
Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice
-
Fan G, Xiao L, Cheng L, Wang X, Sun B, Hu G. 2000. Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice. FEBS Lett 467:7-11.
-
(2000)
FEBS Lett
, vol.467
, pp. 7-11
-
-
Fan, G.1
Xiao, L.2
Cheng, L.3
Wang, X.4
Sun, B.5
Hu, G.6
-
7
-
-
24944446028
-
Cerebral hypoplasia and craniofacial defects in mice lacking heparin sulfate ndst1 gene function
-
Grobe K, Inatani M, Palleria SR, Castagnola J, Yamaguchi Y, Esko JD. 2005. Cerebral hypoplasia and craniofacial defects in mice lacking heparin sulfate ndst1 gene function. Development 132:3777-3786.
-
(2005)
Development
, vol.132
, pp. 3777-3786
-
-
Grobe, K.1
Inatani, M.2
Palleria, S.R.3
Castagnola, J.4
Yamaguchi, Y.5
Esko, J.D.6
-
8
-
-
34447527790
-
Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation and late embryonic lethality
-
Habuchi H, Nagai N, Sugaya N, Atsumi F, Stevens RI, Kimata K. 2007. Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation and late embryonic lethality. J Biol Chem 282:15578-15588.
-
(2007)
J Biol Chem
, vol.282
, pp. 15578-15588
-
-
Habuchi, H.1
Nagai, N.2
Sugaya, N.3
Atsumi, F.4
Stevens, R.I.5
Kimata, K.6
-
9
-
-
0034723420
-
The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine
-
Habuchi H, Tanaka M, Habuchi O, Yoshida K, Suzuki H, Ban K, Kimata K. 2000. The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine. J Biol Chem 275: 2859-2868.
-
(2000)
J Biol Chem
, vol.275
, pp. 2859-2868
-
-
Habuchi, H.1
Tanaka, M.2
Habuchi, O.3
Yoshida, K.4
Suzuki, H.5
Ban, K.6
Kimata, K.7
-
10
-
-
0345471071
-
Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis
-
HajMohammadi S, Enjyoji K, Princivalle M, Christi P, Beeler D, Rayburn H, Schwartz JJ, Barzegar S, deAgostini AI, Post MJ, Rosenberg RD, Shworak NW. 2003. Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis. J Clin Invest 111:989-999.
-
(2003)
J Clin Invest
, vol.111
, pp. 989-999
-
-
HajMohammadi, S.1
Enjyoji, K.2
Princivalle, M.3
Christi, P.4
Beeler, D.5
Rayburn, H.6
Schwartz, J.J.7
Barzegar, S.8
deAgostini, A.I.9
Post, M.J.10
Rosenberg, R.D.11
Shworak, N.W.12
-
11
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro D. 1997. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277:2002-2004.
-
(1997)
Science
, vol.277
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, D.4
-
12
-
-
33644643244
-
Elastin fragments drive disease progression in a murine model of emphysema
-
Houghton AM, Quintero PA, Perkins DL, Kobayashi DK, Kelley DG, Marconcini LA, Mecham RP, Senior RM, Shapiro SD. 2006. Elastin fragments drive disease progression in a murine model of emphysema. J Clin Invest 116:753-759.
-
(2006)
J Clin Invest
, vol.116
, pp. 753-759
-
-
Houghton, A.M.1
Quintero, P.A.2
Perkins, D.L.3
Kobayashi, D.K.4
Kelley, D.G.5
Marconcini, L.A.6
Mecham, R.P.7
Senior, R.M.8
Shapiro, S.D.9
-
13
-
-
0038022636
-
Heparan sulfate-FGF10 interactions during lung morphogenesis
-
Izvolsky KI, Shoykhet D, Yang Y, Yu Q, Nugent MA, Cardoso WV. 2003a. Heparan sulfate-FGF10 interactions during lung morphogenesis. Dev Biol 258:185-200.
-
(2003)
Dev Biol
, vol.258
, pp. 185-200
-
-
Izvolsky, K.I.1
Shoykhet, D.2
Yang, Y.3
Yu, Q.4
Nugent, M.A.5
Cardoso, W.V.6
-
14
-
-
0141568043
-
Heparan sulfates expressed in distal lung are required for Fgf10 binding to the epithelium and for airway branching
-
Izvolsky KI, Zhong L, Wei L, Yu Q, Nugent MA, Cardoso WV. 2003b. Heparan sulfates expressed in distal lung are required for Fgf10 binding to the epithelium and for airway branching. Am J Physiol Lung Cell Mol Physiol 285:L838-L846.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
-
-
Izvolsky, K.I.1
Zhong, L.2
Wei, L.3
Yu, Q.4
Nugent, M.A.5
Cardoso, W.V.6
-
15
-
-
0035907351
-
Drosophila heparin sulfate 6-O-sulfotransferase (dHS6ST) gene. Structure, expression and function in the formation of the tracheal system
-
Kamimura K, Fujise M, Villa F, Izumi S, Habuchi H, Kimata K, Nakato H. 2001. Drosophila heparin sulfate 6-O-sulfotransferase (dHS6ST) gene. Structure, expression and function in the formation of the tracheal system. J Biol Chem 276:17014-17021.
-
(2001)
J Biol Chem
, vol.276
, pp. 17014-17021
-
-
Kamimura, K.1
Fujise, M.2
Villa, F.3
Izumi, S.4
Habuchi, H.5
Kimata, K.6
Nakato, H.7
-
16
-
-
33748527145
-
Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling
-
Kamimura K, Koyama T, Habuchi H, Ueda R, Masu M, Kimata K, Nakato H. 2006. Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling. J Cell Biol 174:773-778.
-
(2006)
J Cell Biol
, vol.174
, pp. 773-778
-
-
Kamimura, K.1
Koyama, T.2
Habuchi, H.3
Ueda, R.4
Masu, M.5
Kimata, K.6
Nakato, H.7
-
17
-
-
33751083837
-
Heparan sulfate 6-O-endosulfatases: Discrete in vivo activities and functional co-operativity
-
Lamanna WC, Baldwin RJ, Padva M, Kalus I, Ten Dam G, van Kuppevelt TH, Gallagher JT, von Figura K, Dierks T, Merry CL. 2006. Heparan sulfate 6-O-endosulfatases: Discrete in vivo activities and functional co-operativity. Biochem J 400:63-73.
-
(2006)
Biochem J
, vol.400
, pp. 63-73
-
-
Lamanna, W.C.1
Baldwin, R.J.2
Padva, M.3
Kalus, I.4
Ten Dam, G.5
van Kuppevelt, T.H.6
Gallagher, J.T.7
von Figura, K.8
Dierks, T.9
Merry, C.L.10
-
18
-
-
0043210538
-
Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparin sulfate lacking L-iduronic acid and in neonatal lethality
-
Li JP, Gong F, Hagner- McWhirter A, Forsberg E, Abrink M, Kisilevsky R, Zhang X, Lindahl U. 2003. Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparin sulfate lacking L-iduronic acid and in neonatal lethality. J Biol Chem 278:28363-28366.
-
(2003)
J Biol Chem
, vol.278
, pp. 28363-28366
-
-
Li, J.P.1
Gong, F.2
Hagner- McWhirter, A.3
Forsberg, E.4
Abrink, M.5
Kisilevsky, R.6
Zhang, X.7
Lindahl, U.8
-
19
-
-
0034253918
-
Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila
-
Lin X, Perrimon N. 2000. Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila. Matrix Biol 19:303-307.
-
(2000)
Matrix Biol
, vol.19
, pp. 303-307
-
-
Lin, X.1
Perrimon, N.2
-
20
-
-
0037352031
-
A highly efficient recombineering-based method for generating conditional knockout mutations
-
Liu P, Jenkins NA, Copeland NG. 2004. A highly efficient recombineering-based method for generating conditional knockout mutations. Genome Res 13:476-484.
-
(2004)
Genome Res
, vol.13
, pp. 476-484
-
-
Liu, P.1
Jenkins, N.A.2
Copeland, N.G.3
-
21
-
-
33846150651
-
Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2
-
Lum DH, Tan J, Rosen SD, Werb Z. 2007. Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2. Mol Cell Biol 27:678-688.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 678-688
-
-
Lum, D.H.1
Tan, J.2
Rosen, S.D.3
Werb, Z.4
-
22
-
-
33846012847
-
Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members
-
MacArthur J, Bishop JR, Stanford KI, Wang L, Bensadoun A, Wiztum JL, Esko JD. 2007. Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members. J Clin Invest 117:153-164.
-
(2007)
J Clin Invest
, vol.117
, pp. 153-164
-
-
MacArthur, J.1
Bishop, J.R.2
Stanford, K.I.3
Wang, L.4
Bensadoun, A.5
Wiztum, J.L.6
Esko, J.D.7
-
23
-
-
0030829521
-
Elastin degradation by matrix metalloproteinases. Cleavage site specificity and mechanisms of elastolysis
-
Mecham RP, Broekelmann TJ, Fliazar CJ, Shapiro SD, Welgua HG, Senior RM. 1997. Elastin degradation by matrix metalloproteinases. Cleavage site specificity and mechanisms of elastolysis. J Biol Chem 272:18071-18076.
-
(1997)
J Biol Chem
, vol.272
, pp. 18071-18076
-
-
Mecham, R.P.1
Broekelmann, T.J.2
Fliazar, C.J.3
Shapiro, S.D.4
Welgua, H.G.5
Senior, R.M.6
-
24
-
-
1542319759
-
Distinctive expression patterns of heparan sulfate O-sulfotransferases and regional differences in heparan sulfate structure in chick limb bubs
-
Nogami K, Suzuki H, Ishiguro N, Iwata H, Kimata K. 2004. Distinctive expression patterns of heparan sulfate O-sulfotransferases and regional differences in heparan sulfate structure in chick limb bubs. J Biol Chem 279:8219-8229.
-
(2004)
J Biol Chem
, vol.279
, pp. 8219-8229
-
-
Nogami, K.1
Suzuki, H.2
Ishiguro, N.3
Iwata, H.4
Kimata, K.5
-
25
-
-
0034730725
-
The proliferative and migratory activities of breast cancer cells can be differentially regulated by heparan sulfates
-
Nurcombe V, Smart CE, Chipperfeld H, Cool SM, Boilly B, Hondermarck H. 2000. The proliferative and migratory activities of breast cancer cells can be differentially regulated by heparan sulfates. J Biol Chem 275:30009-30018.
-
(2000)
J Biol Chem
, vol.275
, pp. 30009-30018
-
-
Nurcombe, V.1
Smart, C.E.2
Chipperfeld, H.3
Cool, S.M.4
Boilly, B.5
Hondermarck, H.6
-
26
-
-
0031443874
-
Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells
-
O'Gorman S, Dagenais NA, Qian M, Marchuk Y. 1997. Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. Proc Natl Acad Sci USA 94:14602-14607.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14602-14607
-
-
O'Gorman, S.1
Dagenais, N.A.2
Qian, M.3
Marchuk, Y.4
-
27
-
-
0033951768
-
FGFs, heparin sulfate and FGFRs: Complex interactions essential for development
-
Ornitz DM. 2000. FGFs, heparin sulfate and FGFRs: Complex interactions essential for development. Bioessays 22:108-112.
-
(2000)
Bioessays
, vol.22
, pp. 108-112
-
-
Ornitz, D.M.1
-
28
-
-
33745963118
-
Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm
-
Pratt T, Conway CD, Tian NM, Price DJ, Mason JO. 2006. Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm. J Neurosci 26:6911-6923.
-
(2006)
J Neurosci
, vol.26
, pp. 6911-6923
-
-
Pratt, T.1
Conway, C.D.2
Tian, N.M.3
Price, D.J.4
Mason, J.O.5
-
29
-
-
0036281205
-
Developmental roles of heparan sulfate proteoglycans: A comparative review in Drosophila, mouse and human
-
Princivalle M, de Agostini A. 2002. Developmental roles of heparan sulfate proteoglycans: A comparative review in Drosophila, mouse and human. Int J Dev Biol 46:267-278.
-
(2002)
Int J Dev Biol
, vol.46
, pp. 267-278
-
-
Princivalle, M.1
de Agostini, A.2
-
30
-
-
0034714226
-
Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/ N-sulfotransferase-1
-
Ringvall M, Ledin J, Holmborn K, vanKuppevelt T, Ellin F, Eriksson I, Olofsson AM, Kjellen L, Forsberg E. 2000. Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/ N-sulfotransferase-1. J Biol Chem 275:25926-25930.
-
(2000)
J Biol Chem
, vol.275
, pp. 25926-25930
-
-
Ringvall, M.1
Ledin, J.2
Holmborn, K.3
vanKuppevelt, T.4
Ellin, F.5
Eriksson, I.6
Olofsson, A.M.7
Kjellen, L.8
Forsberg, E.9
-
31
-
-
11144263717
-
Differential expression of heparan sulfate 6-O-sulfotransferase isoforms in the mouse embryo suggests distinctive roles during organogenesis
-
Sedita J, Izvolsky KI, Cardoso WV. 2004. Differential expression of heparan sulfate 6-O-sulfotransferase isoforms in the mouse embryo suggests distinctive roles during organogenesis. Dev Dyn 231:782-794.
-
(2004)
Dev Dyn
, vol.231
, pp. 782-794
-
-
Sedita, J.1
Izvolsky, K.I.2
Cardoso, W.V.3
-
32
-
-
33746637530
-
New insights into the inhibition of human neutrophil elastase by heparin
-
Spencer JL, Stone PJ, Nugent MA. 2006. New insights into the inhibition of human neutrophil elastase by heparin. Biochemistry 45:9104-9120.
-
(2006)
Biochemistry
, vol.45
, pp. 9104-9120
-
-
Spencer, J.L.1
Stone, P.J.2
Nugent, M.A.3
-
33
-
-
85047690914
-
Mice lacking syndecan-3 gene are resistant to diet-induced obesity
-
Strader AD, Reizes O, Woods SC, Benoit SC, Steely RJ. 2004. Mice lacking syndecan-3 gene are resistant to diet-induced obesity. J Clin Invest 114:1354-1360.
-
(2004)
J Clin Invest
, vol.114
, pp. 1354-1360
-
-
Strader, A.D.1
Reizes, O.2
Woods, S.C.3
Benoit, S.C.4
Steely, R.J.5
-
34
-
-
1842737772
-
QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis
-
Wang S, Ai X, Freeman SD, Pownall ME, Lu Q, Kessler DS, Emerson CP Jr. 2004. QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis. Proc Natl Acad Sci USA 101:4833-4838.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4833-4838
-
-
Wang, S.1
Ai, X.2
Freeman, S.D.3
Pownall, M.E.4
Lu, Q.5
Kessler, D.S.6
Emerson Jr., C.P.7
-
35
-
-
23044444804
-
Heparan sulfate: A complex polymer charged with biological activity
-
Whitelock JM, Iozzo RV. 2005. Heparan sulfate: A complex polymer charged with biological activity. Chem Rev 105:2745-2764.
-
(2005)
Chem Rev
, vol.105
, pp. 2745-2764
-
-
Whitelock, J.M.1
Iozzo, R.V.2
-
36
-
-
10744232455
-
Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior
-
Zcharia E, Metzger S, Chajek-Shaul T, Aingorn H, Elkin M, Friedmann Y, Weinstein T, Li JP, Lindahl U, Vlodavsky I. 2004. Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior. FASEB J 18:252-263.
-
(2004)
FASEB J
, vol.18
, pp. 252-263
-
-
Zcharia, E.1
Metzger, S.2
Chajek-Shaul, T.3
Aingorn, H.4
Elkin, M.5
Friedmann, Y.6
Weinstein, T.7
Li, J.P.8
Lindahl, U.9
Vlodavsky, I.10
|