Retinoid X receptor α is highly phosphorylated in retinoic acid-resistant HL-60R cells and the combination of 9-cis retinoic acid plus MEK inhibitor induces apoptosis in the cells

Leukemia Research

Volumn 32, Issue 6, 2008, Pages 884-892

  Kanemura, Nobuhiro ^a   Tsurumi, Hisashi ^a   Okuno, Masataka ^a   Matsushima Nishiwaki, Rie ^a   Shimizu, Masahito ^a   Moriwaki, Hisataka ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

9 cis RA; Apoptosis; HL 60; HL 60R; MEK inhibitor; RXR

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALITRETINOIN; RETINOIC ACID; RETINOID X RECEPTOR ALPHA;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

APOPTOSIS; BLOTTING, WESTERN; BUTADIENES; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; FLAVONOIDS; HL-60 CELLS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NITRILES; PHOSPHORYLATION; RETINOID X RECEPTOR ALPHA; TRETINOIN;

EID: 40849139372     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2007.11.005     Document Type: Article

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