Activation of retinoid receptors RARα and RXRα induces differentiation and apoptosis, respectively, in HL-60 cells

Cell Growth and Differentiation

Volumn 7, Issue 2, 1996, Pages 179-186

  Mehta, Kapil ^a   McQueen, Teresa ^a   Neamati, Nouri ^a   Collins, Steven ^b   Andreeff, Michael ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECEPTOR SUBUNIT; RETINOIC ACID RECEPTOR;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; EXPRESSION VECTOR; GENE MUTATION; GRANULOCYTE; GROWTH REGULATION; GROWTH STIMULATION; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR UPREGULATION; RETROVIRUS;

ADP-RIBOSYL CYCLASE; ANTIGENS, CD; ANTIGENS, CD38; ANTIGENS, DIFFERENTIATION; APOPTOSIS; CELL DIFFERENTIATION; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION; HL-60 CELLS; HUMANS; IN SITU HYBRIDIZATION; MEMBRANE GLYCOPROTEINS; MUTATION; N-GLYCOSYL HYDROLASES; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSGLUTAMINASES; TRETINOIN;

EID: 0030071518     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Metcalf, D. The molecular control of division, differentiation commitment, and maturation in hematopoietic cells. Nature (Lond.), 339: 27-30, 1989.
2. Marx, J Cell death studies yield cancer clues. Science (Washington DC), 259: 760-761, 1993.
3. Stewart, B. W. Mechanisms of apoptosis: integration of genetic, biochemical, and cellular indicators. J. Natl. Cancer Inst., 86: 1286-1295, 1994.
4. Steller, H. Mechanisms and genes of cellular suicide. Science (Washington DC), 267: 1445-1449, 1995.
5. Breitman, T. R., Selonick, S. E., and Collins, S. J. Induction of differentiation of the human promyelocyttc leukemia cell line (HL-60) by retinoic acid. Proc. Natl. Acad. Sci. USA, 77: 2936-2940, 1980.
6. Martin, S. J., Bradley, J. G., and Cotter, T. G. HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis. Clin. Exp. Immunol., 79: 448-453, 1990.
7. Pfahl, M., Apfel, R., Bendik, I., Fanjul, A., Graupner, G., Lee, M., La-Vista, N., Lu, X., Piedrafita, J., Ortiz, M. A., Salbert, G., and Zhang, X. Nuclear retinoid receptors and their mechanisms of action. Vitam. Horm., 49: 327-381, 1994.
8. Mangelsdorf, D. J., Umesono, K., and Evans, R. M. The retinoid receptors. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds), The Retinoids, pp. 319-349. New York: Raven Press, 1994.
9. Chambon, P The retinoids signaling pathway, molecular and genetic analysis. Semin. Cell Biol., 5: 115-125, 1994.
10. Giguere, V., Ong, E. S., Seul, P., and Evans, R. M. Identification of a receptor for the morphogen retinoic acid Nature (Lond.), 330: 624-629, 1987.
11. Levin, A. A., Sturzenbecker, L. J., Kazmer, S., Bosalkowski, T., Huselton, C., Allenby, G., Speck, G., Kratzeisen, C. I., Rosenberger, M , Lovey, A., and Grippo, J. F. 9-cis Retinoic acid stereoisomer binds and activates the nuclear receptor RXRα. Nature (Lond.), 355: 359-361, 1992.
12. Heyman, R. A., Mangelsdorf, D. J., Dyck, J. A., Stein, R. B., Eichele, G., Evans, R. M., and Thaller, C. 9-cis Retinoic acid is a high affinity ligand for the retinoid X receptor Cell, 68: 397-406, 1992.
13. Rees, J The molecular biology of retinoic acid receptors: orphan from good family seeks home. Br. J. Dermatol., 126: 97-104, 1992.
14. Hashimoto, Y., Kagechika, H., and Shudo, K. Expression of retinoic acid receptor genes and ligand-binding selectivity of retinoic acid receptors. Biochem. Biophys. Res. Commun., 766: 1300-1307, 1990.
15. Robertson, K. A., Emami, B., and Collins, S. J. Retinoic acid-resistant HL-60R cells harbor a point mutation in the retinoic acid receptor ligand-binding domain that confers dominant negative activity. Blood, 80: 1885-1889, 1992.
16. Robertson, K. A., Emami, B., Lueller, L., and Collins, S. J. Multiple members of the retinoic acid receptor family are capable of mediating the granulocytic differentiation of HL-60 cells. Mol. Cell. Biol., 12: 3743-3749, 1992.
17. Drach, J., McQueen, T., Engel, H., Andreeff, M., Robertson, K. A., Colfins, S. J., Malavasi, F., and Mehta, K. Retinoic acid-induced expression of CD38 antigen in myeloid cells is mediated through retinoic acid receptor-α. Cancer Res., 54: 1746-1752, 1994.
18. Drach, J., Zhao, S., Malavasi, F., and Mehta, K. Rapid induction of CD38 antigen on myeloid leukemia cells by retinoic acid. Biochem. Biophys. Res. Commun., 195: 545-550, 1993.
19. Kontanio, K., Nishina, H., Ohoka, Y., Takahashi, K., and Katada, D. NAD glycohydrolase specifically induced by retinoic acid in human leukemic HL-60 cells. J. Biol. Chem , 268: 16895-16898, 1993.
20. Davies, P. J., Murfaugh, M. P., Moore, W. T., Johnson, G. S., and Lucas, D. Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells. J. Biol. Chem., 260: 5166-5174, 1985.
21. Suuier, M K. T., Sehnert, A. J., and Cohen, J. J. Apoptosis in leukocytes. J. Leukocyte Biol., 57: 2-10, 1995.
22. Nagy, L., Thomazy, V. A., Shipley, G. L., Fesus, L., Lamph, W., Heyman, R. A., Chandraratna, R. A. S., and Davies, P. J. A. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol. Cell. Biol., 15: 3540-3551, 1995.
23. Mangelsdorf, D. J., Ong, E. S., Dyck, J. A., and Evans, R. M. A nuclear receptor that identifies a novel retinoic acid response pathway. Nature (Lond.), 345: 224-229, 1990.
24. Mehta, K., and Berestein, G. L. Expression of tissue transglutaminase in cultured monocytic leukemia (THP-1) cells during differentiation. Cancer Res., 46: 1388-1394, 1986.
25. Murtaugh, M. P., Arend, W. P., and Davies, P. J. A. Induction of tissue transglutaminase in human peripheral blood monocytes. J. Exp Med., 159: 114-125, 1984.
26. Chiocca, E. A., Davies, P. J. A., and Stein, J. P. Regulation of tissue transglutaminase gene expression as a molecular model for retinoid effects on proliferation and differentiation. J. Cell. Biochem., 39: 293-304, 1989.
27. Fesus, L., Davies, P. J. A., and Piacentini, M. Apoptosis: molecular mechanisms in programmed cell death. Eur. J. Cell Biol., 56: 170-177. 1991.
28. Fesus, L. Biochemical events in naturally occurring forms of cell death. FEBS Lett., 328: 1-5, 1993.
29. Jiang, H., and Kochhar, D. M. Induction of tissue transglutaminase and apoptosis by retinoic acid in the limb bud. Teratology, 46; 333-340, 1992.
30. Piacentini, M , Petruzzelli, M A., Oliverio, S., Piredda, L., Biedler, J , and Melino, G. Phenotypic-specific tissue transglutaminase regulation in human neuroblastoma cells in response to retinoic acid: correlation with cell death by apoptosis. Int. J. Cancer, 52: 271-278, 1992.
31. Zhang, L-X., Mills, K. J., Dawson, M. I., Collins, S. J., and Jetten, A M Evidence for the involvement of retinoic acid receptor α-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids. J. Biol. Chem , 270: 6022-6029, 1995.
32. Kumagai, M., Smith, E C , Murray, D. J., Silvennoinen, O., Murti, K G., Evans, W. E., Malavasi, F., and Campana, D. Ligation of CD38 suppresses human B lymphopoiesis. J. Exp. Med., 181: 1101-1110, 1995.
33. Zupo, S., Rugari, E., Dono, M., Taborelli, G , Malavasi, F., and Ferrarini, M. CD38 signaling by agonistic monoclonal antibody prevents apoptosis of human germinal center B cells. Eur. J. Immunol., 24: 1218-1222, 1995.
34. Collins, S., Robertson, K. A., and Mueller, L. Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RARα). Mol. Cell. Biol., 70, 2154-2163, 1990.
35. Mehta, K. High levels of transglutaminase expression in doxorubicin-resistant human breast carcinoma cells. Int. J. Cancer, 58: 400-406, 1994.