Two conformational states of Ras GTPase exhibit differential GTP-binding kinetics

Biochemical and Biophysical Research Communications

Volumn 369, Issue 2, 2008, Pages 327-332

  Liao, Jingling ^a   Shima, Fumi ^a   Araki, Mitsugu ^b   Ye, Min ^a   Muraoka, Shin ^a   Sugimoto, Takeshi ^a   Kawamura, Mei ^b   Yamamoto, Naoki ^b   Tamura, Atsuo ^b   Kataoka, Tohru ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KOBE UNIVERSITY   (Japan)

Author keywords

31P nuclear magnetic resonance; Conformational states; GTP association and dissociation kinetics; H Ras; M Ras; RalA; Rap; Small GTPases

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; K RAS PROTEIN; RAS PROTEIN;

ARTICLE; BINDING KINETICS; CONFORMATIONAL TRANSITION; DISSOCIATION; ENZYME CONFORMATION; ENZYME KINETICS; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; THERMODYNAMICS;

BINDING SITES; COMPUTER SIMULATION; GUANOSINE TRIPHOSPHATE; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; RAS GTPASE-ACTIVATING PROTEINS;

EID: 40849137620     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.01.169     Document Type: Article

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