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Volumn 19, Issue 2, 1998, Pages 331-335

Chronic liver injury promotes hepatocarcinogenesis of the LEC rat

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE;

EID: 0031926584     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.2.331     Document Type: Article
Times cited : (26)

References (36)
  • 1
    • 0025187757 scopus 로고
    • Phenotype of preneoplastic and neoplastic liver lesions during spontaneous liver carcinogenesis of LEC rats
    • Sawaki, M., Enomoto, K., Takahashi, H., Nakajima, Y. and Mori, M. (1990) Phenotype of preneoplastic and neoplastic liver lesions during spontaneous liver carcinogenesis of LEC rats. Carcinogenesis, 11, 1857-1861.
    • (1990) Carcinogenesis , vol.11 , pp. 1857-1861
    • Sawaki, M.1    Enomoto, K.2    Takahashi, H.3    Nakajima, Y.4    Mori, M.5
  • 2
    • 0025892297 scopus 로고
    • Spontaneous hepatic copper accumulation in Long-Evans cinnamon rats with hereditary hepatitis: A model of Wilson's disease
    • Li, Y., Togashi, Y., Sato, S. et al. (1991) Spontaneous hepatic copper accumulation in Long-Evans cinnamon rats with hereditary hepatitis: A model of Wilson's disease. J. Clin. Invest., 87, 1858-1861.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1858-1861
    • Li, Y.1    Togashi, Y.2    Sato, S.3
  • 3
    • 0026589734 scopus 로고
    • Genetic linkage between copper accumulation and hepatitis/hepatoma development in LEC rats
    • Sone, H., Maeda, M., Gotoh, M. et al. (1992) Genetic linkage between copper accumulation and hepatitis/hepatoma development in LEC rats. Mol. Carcinogenesis, 5, 199-204.
    • (1992) Mol. Carcinogenesis , vol.5 , pp. 199-204
    • Sone, H.1    Maeda, M.2    Gotoh, M.3
  • 4
    • 0027989674 scopus 로고
    • The gene responsible for LEC hepatitis, located on rat chromosome 16, is the homolog to the human Wilson disease gene
    • Sasaki, N., Hayashizaki, Y., Muramatsu, M. et al. (1994) The gene responsible for LEC hepatitis, located on rat chromosome 16, is the homolog to the human Wilson disease gene. Biochem. Biophys. Res. Commun., 202, 512-518.
    • (1994) Biochem. Biophys. Res. Commun. , vol.202 , pp. 512-518
    • Sasaki, N.1    Hayashizaki, Y.2    Muramatsu, M.3
  • 6
    • 0028058921 scopus 로고
    • The WD gene for Wilson's disease links to the hepatitis of LEC rats
    • Ono, T., Takada, S. and Yoshida, M.C. (1994) The WD gene for Wilson's disease links to the hepatitis of LEC rats. Japan. J. Cancer Res., 85, 771-774.
    • (1994) Japan. J. Cancer Res. , vol.85 , pp. 771-774
    • Ono, T.1    Takada, S.2    Yoshida, M.C.3
  • 7
    • 0023933449 scopus 로고
    • Hepatitis B virus: The major etiology of hepatocellular carcinoma
    • Beasley, R.P. (1988) Hepatitis B virus: The major etiology of hepatocellular carcinoma. Cancer, 61, 1942-1956.
    • (1988) Cancer , vol.61 , pp. 1942-1956
    • Beasley, R.P.1
  • 10
    • 0025334672 scopus 로고
    • Hepatocarcinogenesis due to chronic liver injury in hepatitis B virus transgenic mice
    • Dunsford, H.A., Sell, S. and Chisari, F.V. (1990) Hepatocarcinogenesis due to chronic liver injury in hepatitis B virus transgenic mice. Cancer Res., 50, 3400-3407.
    • (1990) Cancer Res. , vol.50 , pp. 3400-3407
    • Dunsford, H.A.1    Sell, S.2    Chisari, F.V.3
  • 12
    • 0026544305 scopus 로고
    • D-penicillamine prevents the development of hepatitis in Long-Evans Cinnamon rats with abnormal copper metabolism
    • Togashi, Y. Li, Y., Kang, J.-H., Takeichi, N., Fujioka, Y., Nagashima, K. and Kobayashi, H. (1992) D-penicillamine prevents the development of hepatitis in Long-Evans Cinnamon rats with abnormal copper metabolism. Hepatology, 15, 82-87.
    • (1992) Hepatology , vol.15 , pp. 82-87
    • Togashi, Y.1    Li, Y.2    Kang, J.-H.3    Takeichi, N.4    Fujioka, Y.5    Nagashima, K.6    Kobayashi, H.7
  • 13
    • 0027290762 scopus 로고
    • Prevention of spontaneous hepatocellular carcinoma in Long-Evans Cinnamon rats with hereditary hepatitis by the administration of D-penicillamine
    • Kang, J.-H., Togashi, Y., Kasai, H., Hosokawa, M. and Takeichi, N. (1993) Prevention of spontaneous hepatocellular carcinoma in Long-Evans Cinnamon rats with hereditary hepatitis by the administration of D-penicillamine. Hepatology, 18, 614-620.
    • (1993) Hepatology , vol.18 , pp. 614-620
    • Kang, J.-H.1    Togashi, Y.2    Kasai, H.3    Hosokawa, M.4    Takeichi, N.5
  • 14
    • 0017375321 scopus 로고
    • Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies
    • Bieri, J.G., Stoewsand, G.S., Briggs, G.M., Phillips, R.W., Woodard, J.C. and Knapka, J.J. (1977) Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies. J. Nutr., 107, 1340-1348.
    • (1977) J. Nutr. , vol.107 , pp. 1340-1348
    • Bieri, J.G.1    Stoewsand, G.S.2    Briggs, G.M.3    Phillips, R.W.4    Woodard, J.C.5    Knapka, J.J.6
  • 15
    • 0020070809 scopus 로고
    • Application of quantitative stereology to the evaluation of enzyme-altered foci in rat liver
    • Campbell, H.A., Pitot, H.C., Potter, V.R. and Laishes, B.A. (1982) Application of quantitative stereology to the evaluation of enzyme-altered foci in rat liver. Cancer Res., 42, 465-472.
    • (1982) Cancer Res. , vol.42 , pp. 465-472
    • Campbell, H.A.1    Pitot, H.C.2    Potter, V.R.3    Laishes, B.A.4
  • 16
    • 0026425821 scopus 로고
    • Copper metabolism in the LEC rat: Involvement of induction of metallothionein and disposition of zinc and iron
    • Sugawara, N., Sugawara, C., Katakura, M., Takahashi, H. and Mori, M. (1991) Copper metabolism in the LEC rat: involvement of induction of metallothionein and disposition of zinc and iron. Experimentia, 47, 1060-1063.
    • (1991) Experimentia , vol.47 , pp. 1060-1063
    • Sugawara, N.1    Sugawara, C.2    Katakura, M.3    Takahashi, H.4    Mori, M.5
  • 17
    • 0019857598 scopus 로고
    • Histochemical detection of zinc and copper in various neurons of the central nervous system
    • Kozma, M., Szerdahelyi, P. and Kása, P. (1981) Histochemical detection of zinc and copper in various neurons of the central nervous system. Acta Histochem., 69, 12-16.
    • (1981) Acta Histochem. , vol.69 , pp. 12-16
    • Kozma, M.1    Szerdahelyi, P.2    Kása, P.3
  • 18
    • 0027196120 scopus 로고
    • Mechanisms of multistep carcinogenesis and carcinogen risk assessment
    • Barrett, J.C. (1993) Mechanisms of multistep carcinogenesis and carcinogen risk assessment. Environ. Health Perspect., 100, 9-20.
    • (1993) Environ. Health Perspect. , vol.100 , pp. 9-20
    • Barrett, J.C.1
  • 19
    • 0025168534 scopus 로고
    • Cell proliferation in carcinogenesis
    • Cohen, S.M. and Ellwein, L.B. (1990) Cell proliferation in carcinogenesis. Science, 249, 1007-1011.
    • (1990) Science , vol.249 , pp. 1007-1011
    • Cohen, S.M.1    Ellwein, L.B.2
  • 20
    • 0025775739 scopus 로고
    • Hepatocyte proliferation in stepwise development of experimental liver cell cancer
    • Farber, E. (1991) Hepatocyte proliferation in stepwise development of experimental liver cell cancer. Dig. Dis. Sci., 36, 973-978.
    • (1991) Dig. Dis. Sci. , vol.36 , pp. 973-978
    • Farber, E.1
  • 21
    • 85045533444 scopus 로고    scopus 로고
    • Inhibition of hereditary hepatitis and liver tumor development in Long-Evans cinnamon rats by the copper-chelating agent trientine dihydrochloride
    • Sone, K., Maeda, M., Wakabayashi, K., Takeichi, N., Mori, M., Sugimura, T. and Nagao, M. (1996) Inhibition of hereditary hepatitis and liver tumor development in Long-Evans cinnamon rats by the copper-chelating agent trientine dihydrochloride. Hepatology, 23, 764-770.
    • (1996) Hepatology , vol.23 , pp. 764-770
    • Sone, K.1    Maeda, M.2    Wakabayashi, K.3    Takeichi, N.4    Mori, M.5    Sugimura, T.6    Nagao, M.7
  • 22
    • 16044364386 scopus 로고    scopus 로고
    • Hepatocyte growth factor and c-met expression in Long-Evans Cinnamon rats with spontaneous hepatitis and hepatoma
    • Nakayama, N., Kashiwazaki, H., Kobayashi, N. et al. (1996) Hepatocyte growth factor and c-met expression in Long-Evans Cinnamon rats with spontaneous hepatitis and hepatoma. Hepatology, 24, 596-602.
    • (1996) Hepatology , vol.24 , pp. 596-602
    • Nakayama, N.1    Kashiwazaki, H.2    Kobayashi, N.3
  • 23
    • 0027296545 scopus 로고
    • DNA damage resulting from the oxidation of hydroquinone by copper: Role for a Cu(II)/Cu(I) redox cycle and reactive oxygen generation
    • Li, Y. and Trush, M.A. (1993) DNA damage resulting from the oxidation of hydroquinone by copper: role for a Cu(II)/Cu(I) redox cycle and reactive oxygen generation. Carcinogenesis, 14, 1303-1311.
    • (1993) Carcinogenesis , vol.14 , pp. 1303-1311
    • Li, Y.1    Trush, M.A.2
  • 24
    • 0028237181 scopus 로고
    • DNA damage caused by reactive oxygen species originating from a copper-dependent oxidation of the 2-hydroxy catechol of estradiol
    • Li, Y., Trush, M.A. and Yager, J.D. (1994) DNA damage caused by reactive oxygen species originating from a copper-dependent oxidation of the 2-hydroxy catechol of estradiol. Carcinogenesis, 15, 1421-1427.
    • (1994) Carcinogenesis , vol.15 , pp. 1421-1427
    • Li, Y.1    Trush, M.A.2    Yager, J.D.3
  • 25
    • 0027273337 scopus 로고
    • Elevated level of 8-hydroxydeoxyguanosine in DNA of liver, kidney and brain of Long-Evans cinnamon rats
    • Yamamoto, F., Kasai, H., Togashi, Y., Takeichi, N., Hori, T. and Nishimura, S. (1993) Elevated level of 8-hydroxydeoxyguanosine in DNA of liver, kidney and brain of Long-Evans cinnamon rats. Japan. J. Cancer Res., 84, 508-511.
    • (1993) Japan. J. Cancer Res. , vol.84 , pp. 508-511
    • Yamamoto, F.1    Kasai, H.2    Togashi, Y.3    Takeichi, N.4    Hori, T.5    Nishimura, S.6
  • 26
    • 0029877988 scopus 로고    scopus 로고
    • Copper-dependent formation of miscoding etheno-DNA adducts in the liver of Long-Evans cinnamon (LEC) rats developing hereditary hepatitis and hepatocellular carcinoma
    • Nair, J., Sone, H., Nagan, M., Barbin, A. and Bartsch, H. (1996) Copper-dependent formation of miscoding etheno-DNA adducts in the liver of Long-Evans cinnamon (LEC) rats developing hereditary hepatitis and hepatocellular carcinoma. Cancer Res., 56, 1267-1271.
    • (1996) Cancer Res. , vol.56 , pp. 1267-1271
    • Nair, J.1    Sone, H.2    Nagan, M.3    Barbin, A.4    Bartsch, H.5
  • 27
    • 0015619069 scopus 로고
    • The inhibitory effect of copper on DL-ethionine carcinogenesis in rats
    • Kamamoto, Y., Makiura, S., Sugihara, S., Hiasa, Y., Arai, M. and Ito, N. (1973) The inhibitory effect of copper on DL-ethionine carcinogenesis in rats. Cancer Res., 33, 1129-1135.
    • (1973) Cancer Res. , vol.33 , pp. 1129-1135
    • Kamamoto, Y.1    Makiura, S.2    Sugihara, S.3    Hiasa, Y.4    Arai, M.5    Ito, N.6
  • 28
    • 0021673658 scopus 로고
    • Suppressive effect of cupric acetate on DNA alkylation, DNA synthesis and tumorigenesis in the liver of dimethylnitrosamine-treated rats
    • Yamane, Y., Sakai, K., Umeda, T., Murata, N., Ishizeki, S., Ogihara, I., Takahashi, A., Iwasaki, I. and Ide, G. (1984) Suppressive effect of cupric acetate on DNA alkylation, DNA synthesis and tumorigenesis in the liver of dimethylnitrosamine-treated rats. Gann, 75, 1062-1069.
    • (1984) Gann , vol.75 , pp. 1062-1069
    • Yamane, Y.1    Sakai, K.2    Umeda, T.3    Murata, N.4    Ishizeki, S.5    Ogihara, I.6    Takahashi, A.7    Iwasaki, I.8    Ide, G.9
  • 29
    • 0023986684 scopus 로고
    • Multistage carcinogenesis: Implications for risk estimation
    • Yamasaki, H. (1988) Multistage carcinogenesis: implications for risk estimation. Cancer Metastas. Rev., 7, 5-18.
    • (1988) Cancer Metastas. Rev. , vol.7 , pp. 5-18
    • Yamasaki, H.1
  • 30
    • 0026047638 scopus 로고
    • Perspectives in the risk assessment for nongenotoxic carcinogens and tumor promoters
    • Perera, F.P. (1991) Perspectives in the risk assessment for nongenotoxic carcinogens and tumor promoters. Environ. Health Perspect., 94, 231-235.
    • (1991) Environ. Health Perspect. , vol.94 , pp. 231-235
    • Perera, F.P.1
  • 31
    • 0028070217 scopus 로고
    • Role of copper accumulation and metallothionein induction in spontaneous liver cancer development in LEC rats
    • Sawaki, M., Enomoto, K., Hattori, A., Tsuzuki, N., Sugawara, N. and Mori, M. (1994) Role of copper accumulation and metallothionein induction in spontaneous liver cancer development in LEC rats. Carcinogenesis, 15, 1833-1837.
    • (1994) Carcinogenesis , vol.15 , pp. 1833-1837
    • Sawaki, M.1    Enomoto, K.2    Hattori, A.3    Tsuzuki, N.4    Sugawara, N.5    Mori, M.6
  • 32
    • 10544241198 scopus 로고    scopus 로고
    • waf-1/cip-1 is significantly induced in the livers of LEC rats with chronic liver injury
    • waf-1/cip-1 is significantly induced in the livers of LEC rats with chronic liver injury. Japan. J. Cancer Res., 87, 1102-1105.
    • (1996) Japan. J. Cancer Res. , vol.87 , pp. 1102-1105
    • Sawada, N.1    Kojima, T.2    Obata, H.3
  • 35
    • 0025323886 scopus 로고
    • High sensitivity of the LEC rat liver to the carcinogenic effect of diethyl-nitrosamine
    • Takahashi, H., Enomoto, K., Nakajima, Y. and Mori, M. (1990) High sensitivity of the LEC rat liver to the carcinogenic effect of diethyl-nitrosamine. Cancer Lett., 51, 247-250.
    • (1990) Cancer Lett. , vol.51 , pp. 247-250
    • Takahashi, H.1    Enomoto, K.2    Nakajima, Y.3    Mori, M.4
  • 36
    • 0028963038 scopus 로고
    • The high hepatocarcinogen susceptibility of LEC rats is genetically independent of abnormal copper accumulation in the liver
    • Hattori, A., Sawaki, M., Enomoto, K. et al. (1995) The high hepatocarcinogen susceptibility of LEC rats is genetically independent of abnormal copper accumulation in the liver. Carcinogenesis, 16, 491-494.
    • (1995) Carcinogenesis , vol.16 , pp. 491-494
    • Hattori, A.1    Sawaki, M.2    Enomoto, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.