메뉴 건너뛰기




Volumn 26, Issue 15, 2008, Pages 1902-1911

Immunogenicity of HSP-70, KMP-11 and PFR-2 leishmanial antigens in the experimental model of canine visceral leishmaniasis

Author keywords

Canine; Cytokine; HSP 70; Immunogenicity; KMP 11; Leishmania; PFR 2

Indexed keywords

GAMMA INTERFERON; HEAT SHOCK PROTEIN 70; INTERLEUKIN 10; KINETOPLASTIDA MEMBRANE PROTEIN 11; MESSENGER RNA; PARAFLAGELLAR ROD PROTEIN 2; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 40849114492     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.01.042     Document Type: Article
Times cited : (56)

References (54)
  • 1
    • 25844450908 scopus 로고    scopus 로고
    • The current status of zoonotic leishmaniases and approaches to disease control
    • Gramiccia M., and Gradoni L. The current status of zoonotic leishmaniases and approaches to disease control. Int J Parasitol 35 11-12 (2005) 1169-1180
    • (2005) Int J Parasitol , vol.35 , Issue.11-12 , pp. 1169-1180
    • Gramiccia, M.1    Gradoni, L.2
  • 2
    • 0035122732 scopus 로고    scopus 로고
    • Prevalence of Leishmania infantum infection in dogs living in an area of canine leishmaniasis endemicity using PCR on several tissues and serology
    • Solano-Gallego L., Morell P., Arboix M., Alberola J., and Ferrer L. Prevalence of Leishmania infantum infection in dogs living in an area of canine leishmaniasis endemicity using PCR on several tissues and serology. J Clin Microbiol 39 2 (2001) 560-563
    • (2001) J Clin Microbiol , vol.39 , Issue.2 , pp. 560-563
    • Solano-Gallego, L.1    Morell, P.2    Arboix, M.3    Alberola, J.4    Ferrer, L.5
  • 3
    • 0034973071 scopus 로고    scopus 로고
    • Canine visceral leishmaniasis in Colombia: relationship between clinical and parasitologic status and infectivity for sand flies
    • Travi B.L., Tabares C.J., Cadena H., Ferro C., and Osorio Y. Canine visceral leishmaniasis in Colombia: relationship between clinical and parasitologic status and infectivity for sand flies. Am J Trop Med Hyg 64 3-4 (2001) 119-124
    • (2001) Am J Trop Med Hyg , vol.64 , Issue.3-4 , pp. 119-124
    • Travi, B.L.1    Tabares, C.J.2    Cadena, H.3    Ferro, C.4    Osorio, Y.5
  • 4
    • 0036838280 scopus 로고    scopus 로고
    • Infectiousness in a cohort of Brazilian dogs: why culling fails to control visceral leishmaniasis in areas of high transmission
    • Courtenay O., Quinnell R.J., Garcez L.M., Shaw J.J., and Dye C. Infectiousness in a cohort of Brazilian dogs: why culling fails to control visceral leishmaniasis in areas of high transmission. J Infect Dis 186 9 (2002) 1314-1320
    • (2002) J Infect Dis , vol.186 , Issue.9 , pp. 1314-1320
    • Courtenay, O.1    Quinnell, R.J.2    Garcez, L.M.3    Shaw, J.J.4    Dye, C.5
  • 5
    • 0032722008 scopus 로고    scopus 로고
    • The immune response and PBMC subsets in canine visceral leishmaniasis before, and after, chemotherapy
    • Moreno J., Nieto J., Chamizo C., Gonzalez F., Blanco F., Barker D.C., et al. The immune response and PBMC subsets in canine visceral leishmaniasis before, and after, chemotherapy. Vet Immunol Immunopathol 71 3-4 (1999) 181-195
    • (1999) Vet Immunol Immunopathol , vol.71 , Issue.3-4 , pp. 181-195
    • Moreno, J.1    Nieto, J.2    Chamizo, C.3    Gonzalez, F.4    Blanco, F.5    Barker, D.C.6
  • 6
    • 0037007944 scopus 로고    scopus 로고
    • Chemotherapy of canine leishmaniosis
    • Baneth G., and Shaw S.E. Chemotherapy of canine leishmaniosis. Vet Parasitol 106 4 (2002) 315-324
    • (2002) Vet Parasitol , vol.106 , Issue.4 , pp. 315-324
    • Baneth, G.1    Shaw, S.E.2
  • 7
    • 14644426496 scopus 로고    scopus 로고
    • Clinical and serological follow-up in dogs with visceral leishmaniosis treated with allopurinol and sodium stibogluconate
    • Pasa S., Toz S.O., Voyvoda H., and Ozbel Y. Clinical and serological follow-up in dogs with visceral leishmaniosis treated with allopurinol and sodium stibogluconate. Vet Parasitol 128 3-4 (2005) 243-249
    • (2005) Vet Parasitol , vol.128 , Issue.3-4 , pp. 243-249
    • Pasa, S.1    Toz, S.O.2    Voyvoda, H.3    Ozbel, Y.4
  • 8
    • 16344365616 scopus 로고    scopus 로고
    • Efficacy of the treatment of dogs with leishmaniosis with a combination of metronidazole and spiramycin
    • Pennisi M.G., De Majo M., Masucci M., Britti D., Vitale F., and Del Maso R. Efficacy of the treatment of dogs with leishmaniosis with a combination of metronidazole and spiramycin. Vet Rec 156 11 (2005) 346-349
    • (2005) Vet Rec , vol.156 , Issue.11 , pp. 346-349
    • Pennisi, M.G.1    De Majo, M.2    Masucci, M.3    Britti, D.4    Vitale, F.5    Del Maso, R.6
  • 9
    • 0028021421 scopus 로고
    • Canine leishmaniasis: clinical, parasitological and entomological follow-up after chemotherapy
    • Alvar J., Molina R., San Andres M., Tesouro M., Nieto J., Vitutia M., et al. Canine leishmaniasis: clinical, parasitological and entomological follow-up after chemotherapy. Ann Trop Med Parasitol 88 4 (1994) 371-378
    • (1994) Ann Trop Med Parasitol , vol.88 , Issue.4 , pp. 371-378
    • Alvar, J.1    Molina, R.2    San Andres, M.3    Tesouro, M.4    Nieto, J.5    Vitutia, M.6
  • 10
    • 0028914552 scopus 로고
    • Control of zoonotic visceral leishmaniasis: is it time to change strategies?
    • Tesh R.B. Control of zoonotic visceral leishmaniasis: is it time to change strategies?. Am J Trop Med Hyg 52 3 (1995) 287-292
    • (1995) Am J Trop Med Hyg , vol.52 , Issue.3 , pp. 287-292
    • Tesh, R.B.1
  • 11
    • 0031800124 scopus 로고    scopus 로고
    • Studies on control of visceral leishmaniasis: impact of dog control on canine and human visceral leishmaniasis in Jacobina, Bahia, Brazil
    • Ashford D.A., David J.R., Freire M., David R., Sherlock I., Eulalio M.C., et al. Studies on control of visceral leishmaniasis: impact of dog control on canine and human visceral leishmaniasis in Jacobina, Bahia, Brazil. Am J Trop Med Hyg 59 1 (1998) 53-57
    • (1998) Am J Trop Med Hyg , vol.59 , Issue.1 , pp. 53-57
    • Ashford, D.A.1    David, J.R.2    Freire, M.3    David, R.4    Sherlock, I.5    Eulalio, M.C.6
  • 12
    • 33846115054 scopus 로고    scopus 로고
    • Immunogenicity of the P-8 amastigote antigen in the experimental model of canine visceral leishmaniasis
    • Carrillo E., Ahmed S., Goldsmith-Pestana K., Nieto J., Osorio Y., Travi B., et al. Immunogenicity of the P-8 amastigote antigen in the experimental model of canine visceral leishmaniasis. Vaccine 25 8 (2007) 1534-1543
    • (2007) Vaccine , vol.25 , Issue.8 , pp. 1534-1543
    • Carrillo, E.1    Ahmed, S.2    Goldsmith-Pestana, K.3    Nieto, J.4    Osorio, Y.5    Travi, B.6
  • 13
    • 24944541478 scopus 로고    scopus 로고
    • Immunogenicity in dogs of three recombinant antigens (TSA LeIF and LmSTI1) potential vaccine candidates for canine visceral leishmaniasis
    • Fujiwara R.T., Vale A.M., Franca da Silva J.C., da Costa R.T., Quetz Jda S., Martins Filho O.A., et al. Immunogenicity in dogs of three recombinant antigens (TSA LeIF and LmSTI1) potential vaccine candidates for canine visceral leishmaniasis. Vet Res 36 5-6 (2005) 827-838
    • (2005) Vet Res , vol.36 , Issue.5-6 , pp. 827-838
    • Fujiwara, R.T.1    Vale, A.M.2    Franca da Silva, J.C.3    da Costa, R.T.4    Quetz Jda, S.5    Martins Filho, O.A.6
  • 15
    • 0034623973 scopus 로고    scopus 로고
    • A phase III trial of efficacy of the FML-vaccine against canine kala-azar in an endemic area of Brazil (Sao Goncalo do Amaranto RN)
    • da Silva V.O., Borja-Cabrera G.P., Correia Pontes N.N., de Souza E.P., Luz K.G., Palatnik M., et al. A phase III trial of efficacy of the FML-vaccine against canine kala-azar in an endemic area of Brazil (Sao Goncalo do Amaranto RN). Vaccine 19 9-10 (2000) 1082-1092
    • (2000) Vaccine , vol.19 , Issue.9-10 , pp. 1082-1092
    • da Silva, V.O.1    Borja-Cabrera, G.P.2    Correia Pontes, N.N.3    de Souza, E.P.4    Luz, K.G.5    Palatnik, M.6
  • 16
    • 0037456693 scopus 로고    scopus 로고
    • A Leishmania infantum multi-component antigenic protein mixed with live BCG confers protection to dogs experimentally infected with L. infantum
    • Molano I., Alonso M.G., Miron C., Redondo E., Requena J.M., Soto M., et al. A Leishmania infantum multi-component antigenic protein mixed with live BCG confers protection to dogs experimentally infected with L. infantum. Vet Immunol Immunopathol 92 1-2 (2003) 1-13
    • (2003) Vet Immunol Immunopathol , vol.92 , Issue.1-2 , pp. 1-13
    • Molano, I.1    Alonso, M.G.2    Miron, C.3    Redondo, E.4    Requena, J.M.5    Soto, M.6
  • 17
    • 15244360706 scopus 로고    scopus 로고
    • Protection against experimental visceral leishmaniasis infection in dogs immunized with purified excreted secreted antigens of Leishmania infantum promastigotes
    • Lemesre J.L., Holzmuller P., Cavaleyra M., Goncalves R.B., Hottin G., and Papierok G. Protection against experimental visceral leishmaniasis infection in dogs immunized with purified excreted secreted antigens of Leishmania infantum promastigotes. Vaccine 23 22 (2005) 2825-2840
    • (2005) Vaccine , vol.23 , Issue.22 , pp. 2825-2840
    • Lemesre, J.L.1    Holzmuller, P.2    Cavaleyra, M.3    Goncalves, R.B.4    Hottin, G.5    Papierok, G.6
  • 18
    • 34250853431 scopus 로고    scopus 로고
    • Immunization with H1, HASPB1 and MML Leishmania proteins in a vaccine trial against experimental canine leishmaniasis
    • Moreno J., Nieto J., Masina S., Canavate C., Cruz I., Chicharro C., et al. Immunization with H1, HASPB1 and MML Leishmania proteins in a vaccine trial against experimental canine leishmaniasis. Vaccine 25 29 (2007) 5290-5300
    • (2007) Vaccine , vol.25 , Issue.29 , pp. 5290-5300
    • Moreno, J.1    Nieto, J.2    Masina, S.3    Canavate, C.4    Cruz, I.5    Chicharro, C.6
  • 19
    • 26644448719 scopus 로고    scopus 로고
    • Failure of a multi-subunit recombinant leishmanial vaccine (MML) to protect dogs from Leishmania infantum infection and to prevent disease progression in infected animals
    • Gradoni L., Foglia Manzillo V., Pagano A., Piantedosi D., De Luna R., Gramiccia M., et al. Failure of a multi-subunit recombinant leishmanial vaccine (MML) to protect dogs from Leishmania infantum infection and to prevent disease progression in infected animals. Vaccine 23 45 (2005) 5245-5251
    • (2005) Vaccine , vol.23 , Issue.45 , pp. 5245-5251
    • Gradoni, L.1    Foglia Manzillo, V.2    Pagano, A.3    Piantedosi, D.4    De Luna, R.5    Gramiccia, M.6
  • 20
    • 0037726800 scopus 로고    scopus 로고
    • Protection in dogs against visceral leishmaniasis caused by Leishmania infantum is achieved by immunization with a heterologous prime-boost regime using DNA and vaccinia recombinant vectors expressing LACK
    • Ramiro M.J., Zarate J.J., Hanke T., Rodriguez D., Rodriguez J.R., Esteban M., et al. Protection in dogs against visceral leishmaniasis caused by Leishmania infantum is achieved by immunization with a heterologous prime-boost regime using DNA and vaccinia recombinant vectors expressing LACK. Vaccine 21 19-20 (2003) 2474-2484
    • (2003) Vaccine , vol.21 , Issue.19-20 , pp. 2474-2484
    • Ramiro, M.J.1    Zarate, J.J.2    Hanke, T.3    Rodriguez, D.4    Rodriguez, J.R.5    Esteban, M.6
  • 21
    • 21044441505 scopus 로고    scopus 로고
    • Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum
    • Rafati S., Nakhaee A., Taheri T., Taslimi Y., Darabi H., Eravani D., et al. Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum. Vaccine 23 28 (2005) 3716-3725
    • (2005) Vaccine , vol.23 , Issue.28 , pp. 3716-3725
    • Rafati, S.1    Nakhaee, A.2    Taheri, T.3    Taslimi, Y.4    Darabi, H.5    Eravani, D.6
  • 22
    • 33344478719 scopus 로고    scopus 로고
    • Vaccination with a preparation based on recombinant cysteine peptidases and canine IL-12 does not protect dogs from infection with Leishmania infantum
    • Poot J., Spreeuwenberg K., Sanderson S.J., Schijns V.E., Mottram J.C., Coombs G.H., et al. Vaccination with a preparation based on recombinant cysteine peptidases and canine IL-12 does not protect dogs from infection with Leishmania infantum. Vaccine 24 14 (2006) 2460-2468
    • (2006) Vaccine , vol.24 , Issue.14 , pp. 2460-2468
    • Poot, J.1    Spreeuwenberg, K.2    Sanderson, S.J.3    Schijns, V.E.4    Mottram, J.C.5    Coombs, G.H.6
  • 23
    • 0038737428 scopus 로고    scopus 로고
    • Role of heat shock proteins in protection from and pathogenesis of infectious diseases
    • Zugel U., and Kaufmann S.H. Role of heat shock proteins in protection from and pathogenesis of infectious diseases. Clin Microbiol Rev 12 1 (1999) 19-39
    • (1999) Clin Microbiol Rev , vol.12 , Issue.1 , pp. 19-39
    • Zugel, U.1    Kaufmann, S.H.2
  • 24
    • 0028980575 scopus 로고
    • Immune responses of leishmaniasis patients to heat shock proteins of Leishmania species and humans
    • Skeiky Y.A., Benson D.R., Guderian J.A., Whittle J.A., Bacelar O., Carvalho E.M., et al. Immune responses of leishmaniasis patients to heat shock proteins of Leishmania species and humans. Infect Immun 63 10 (1995) 4105-4114
    • (1995) Infect Immun , vol.63 , Issue.10 , pp. 4105-4114
    • Skeiky, Y.A.1    Benson, D.R.2    Guderian, J.A.3    Whittle, J.A.4    Bacelar, O.5    Carvalho, E.M.6
  • 25
    • 0033382112 scopus 로고    scopus 로고
    • Immunostimulatory properties of the Leishmania infantum heat shock proteins HSP70 and HSP83
    • Rico A.I., Angel S.O., Alonso C., and Requena J.M. Immunostimulatory properties of the Leishmania infantum heat shock proteins HSP70 and HSP83. Mol Immunol 36 17 (1999) 1131-1139
    • (1999) Mol Immunol , vol.36 , Issue.17 , pp. 1131-1139
    • Rico, A.I.1    Angel, S.O.2    Alonso, C.3    Requena, J.M.4
  • 26
    • 33846270351 scopus 로고    scopus 로고
    • The genetic immunization with paraflagellar rod protein-2 fused to the HSP70 confers protection against late Trypanosoma cruzi infection
    • Morell M., Thomas M.C., Caballero T., Alonso C., and Lopez M.C. The genetic immunization with paraflagellar rod protein-2 fused to the HSP70 confers protection against late Trypanosoma cruzi infection. Vaccine 24 49-50 (2006) 7046-7055
    • (2006) Vaccine , vol.24 , Issue.49-50 , pp. 7046-7055
    • Morell, M.1    Thomas, M.C.2    Caballero, T.3    Alonso, C.4    Lopez, M.C.5
  • 27
    • 0030298228 scopus 로고    scopus 로고
    • Trypanosoma cruzi: protective immunity in mice immunized with paraflagellar rod proteins is associated with a T-helper type 1 response
    • Miller M.J., Wrightsman R.A., and Manning J.E. Trypanosoma cruzi: protective immunity in mice immunized with paraflagellar rod proteins is associated with a T-helper type 1 response. Exp Parasitol 84 2 (1996) 156-167
    • (1996) Exp Parasitol , vol.84 , Issue.2 , pp. 156-167
    • Miller, M.J.1    Wrightsman, R.A.2    Manning, J.E.3
  • 28
    • 11144296349 scopus 로고    scopus 로고
    • Protective immunogenicity of the paraflagellar rod protein 2 of Leishmania mexicana
    • Saravia N.G., Hazbon M.H., Osorio Y., Valderrama L., Walker J., Santrich C., et al. Protective immunogenicity of the paraflagellar rod protein 2 of Leishmania mexicana. Vaccine 23 8 (2005) 984-995
    • (2005) Vaccine , vol.23 , Issue.8 , pp. 984-995
    • Saravia, N.G.1    Hazbon, M.H.2    Osorio, Y.3    Valderrama, L.4    Walker, J.5    Santrich, C.6
  • 29
    • 0028854812 scopus 로고
    • Isolation and structural characterization of the Leishmania donovani kinetoplastid membrane protein-11, a major immunoreactive membrane glycoprotein
    • Jardim A., Funk V., Caprioli R.M., and Olafson R.W. Isolation and structural characterization of the Leishmania donovani kinetoplastid membrane protein-11, a major immunoreactive membrane glycoprotein. Biochem J 305 Pt 1 (1995) 307-313
    • (1995) Biochem J , vol.305 , Issue.PART 1 , pp. 307-313
    • Jardim, A.1    Funk, V.2    Caprioli, R.M.3    Olafson, R.W.4
  • 30
    • 0028874164 scopus 로고
    • Cloning and structure-function analysis of the Leishmania donovani kinetoplastid membrane protein-11
    • Jardim A., Hanson S., Ullman B., McCubbin W.D., Kay C.M., and Olafson R.W. Cloning and structure-function analysis of the Leishmania donovani kinetoplastid membrane protein-11. Biochem J 305 Pt 1 (1995) 315-320
    • (1995) Biochem J , vol.305 , Issue.PART 1 , pp. 315-320
    • Jardim, A.1    Hanson, S.2    Ullman, B.3    McCubbin, W.D.4    Kay, C.M.5    Olafson, R.W.6
  • 31
    • 0031001121 scopus 로고    scopus 로고
    • Cloning of genes and expression and antigenicity analysis of the Leishmania infantum KMP-11 protein
    • Berberich C., Requena J.M., and Alonso C. Cloning of genes and expression and antigenicity analysis of the Leishmania infantum KMP-11 protein. Exp Parasitol 85 1 (1997) 105-108
    • (1997) Exp Parasitol , vol.85 , Issue.1 , pp. 105-108
    • Berberich, C.1    Requena, J.M.2    Alonso, C.3
  • 32
    • 0027515163 scopus 로고
    • Production of interferon-gamma and interleukin-4 by human T cells recognizing Leishmania lipophosphoglycan-associated protein
    • Kemp M., Kurtzhals J.A., Christensen C.B., Kharazmi A., Jardim A., Bendtzen K., et al. Production of interferon-gamma and interleukin-4 by human T cells recognizing Leishmania lipophosphoglycan-associated protein. Immunol Lett 38 2 (1993) 137-144
    • (1993) Immunol Lett , vol.38 , Issue.2 , pp. 137-144
    • Kemp, M.1    Kurtzhals, J.A.2    Christensen, C.B.3    Kharazmi, A.4    Jardim, A.5    Bendtzen, K.6
  • 33
    • 0028319021 scopus 로고
    • Dichotomy of the human T cell response to Leishmania antigens II. Absent or Th2-like response to gp63 and Th1-like response to lipophosphoglycan-associated protein in cells from cured visceral leishmaniasis patients
    • Kurtzhals J.A., Hey A.S., Jardim A., Kemp M., Schaefer K.U., Odera E.O., et al. Dichotomy of the human T cell response to Leishmania antigens II. Absent or Th2-like response to gp63 and Th1-like response to lipophosphoglycan-associated protein in cells from cured visceral leishmaniasis patients. Clin Exp Immunol 96 3 (1994) 416-421
    • (1994) Clin Exp Immunol , vol.96 , Issue.3 , pp. 416-421
    • Kurtzhals, J.A.1    Hey, A.S.2    Jardim, A.3    Kemp, M.4    Schaefer, K.U.5    Odera, E.O.6
  • 34
    • 18944378937 scopus 로고    scopus 로고
    • Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis
    • Basu R., Bhaumik S., Basu J.M., Naskar K., De T., and Roy S. Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis. J Immunol 174 11 (2005) 7160-7171
    • (2005) J Immunol , vol.174 , Issue.11 , pp. 7160-7171
    • Basu, R.1    Bhaumik, S.2    Basu, J.M.3    Naskar, K.4    De, T.5    Roy, S.6
  • 35
  • 36
    • 0036744994 scopus 로고    scopus 로고
    • Canine leishmaniasis: epidemiological risk and the experimental model
    • Moreno J., and Alvar J. Canine leishmaniasis: epidemiological risk and the experimental model. Trends Parasitol 18 9 (2002) 399-405
    • (2002) Trends Parasitol , vol.18 , Issue.9 , pp. 399-405
    • Moreno, J.1    Alvar, J.2
  • 37
    • 0031964659 scopus 로고    scopus 로고
    • Characterization of the immunostimulatory properties of Leishmania infantum HSP70 by fusion to the Escherichia coli maltose-binding protein in normal and nu/nu BALB/c mice
    • Rico A.I., Del Real G., Soto M., Quijada L., Martinez A.C., Alonso C., et al. Characterization of the immunostimulatory properties of Leishmania infantum HSP70 by fusion to the Escherichia coli maltose-binding protein in normal and nu/nu BALB/c mice. Infect Immun 66 1 (1998) 347-352
    • (1998) Infect Immun , vol.66 , Issue.1 , pp. 347-352
    • Rico, A.I.1    Del Real, G.2    Soto, M.3    Quijada, L.4    Martinez, A.C.5    Alonso, C.6
  • 38
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 4 (2001) 402-408
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 39
    • 0026793261 scopus 로고
    • Heat-shock proteins: immunity and autoimmunity
    • Young D.B. Heat-shock proteins: immunity and autoimmunity. Curr Opin Immunol 4 4 (1992) 396-400
    • (1992) Curr Opin Immunol , vol.4 , Issue.4 , pp. 396-400
    • Young, D.B.1
  • 40
    • 21644446582 scopus 로고    scopus 로고
    • Interleukin-12 augments a Th1-type immune response manifested as lymphocyte proliferation and interferon gamma production in Leishmania infantum-infected dogs
    • Strauss-Ayali D., Baneth G., Shor S., Okano F., and Jaffe C.L. Interleukin-12 augments a Th1-type immune response manifested as lymphocyte proliferation and interferon gamma production in Leishmania infantum-infected dogs. Int J Parasitol 35 1 (2005) 63-73
    • (2005) Int J Parasitol , vol.35 , Issue.1 , pp. 63-73
    • Strauss-Ayali, D.1    Baneth, G.2    Shor, S.3    Okano, F.4    Jaffe, C.L.5
  • 41
    • 11144322401 scopus 로고    scopus 로고
    • Semi-quantitative analysis of cytokine expression in asymptomatic canine leishmaniasis
    • Chamizo C., Moreno J., and Alvar J. Semi-quantitative analysis of cytokine expression in asymptomatic canine leishmaniasis. Vet Immunol Immunopathol 103 1-2 (2005) 67-75
    • (2005) Vet Immunol Immunopathol , vol.103 , Issue.1-2 , pp. 67-75
    • Chamizo, C.1    Moreno, J.2    Alvar, J.3
  • 42
    • 32844459122 scopus 로고    scopus 로고
    • Prime-boost vaccination using cysteine proteinases type I and II of Leishmania infantum confers protective immunity in murine visceral leishmaniasis
    • Rafati S., Zahedifard F., and Nazgouee F. Prime-boost vaccination using cysteine proteinases type I and II of Leishmania infantum confers protective immunity in murine visceral leishmaniasis. Vaccine 24 12 (2006) 2169-2175
    • (2006) Vaccine , vol.24 , Issue.12 , pp. 2169-2175
    • Rafati, S.1    Zahedifard, F.2    Nazgouee, F.3
  • 43
    • 0027979703 scopus 로고
    • J. Cellular and humoral immune responses in dogs experimentally and naturally infected with Leishmania infantum
    • Pinelli E., Killick-Kendrick R., Wagenaar J., Bernadina W., Del Real G., and Ruitenberg. J. Cellular and humoral immune responses in dogs experimentally and naturally infected with Leishmania infantum. Infect Immun 62 1 (1994) 229-235
    • (1994) Infect Immun , vol.62 , Issue.1 , pp. 229-235
    • Pinelli, E.1    Killick-Kendrick, R.2    Wagenaar, J.3    Bernadina, W.4    Del Real, G.5    Ruitenberg6
  • 44
    • 0029879714 scopus 로고    scopus 로고
    • During canine viscero-cutaneous leishmaniasis the anti-Hsp70 antibodies are specifically elicited by the parasite protein
    • Quijada L., Requena J.M., Soto M., and Alonso C. During canine viscero-cutaneous leishmaniasis the anti-Hsp70 antibodies are specifically elicited by the parasite protein. Parasitology 112 Pt 3 (1996) 277-284
    • (1996) Parasitology , vol.112 , Issue.PART 3 , pp. 277-284
    • Quijada, L.1    Requena, J.M.2    Soto, M.3    Alonso, C.4
  • 45
    • 0032190655 scopus 로고    scopus 로고
    • Analysis of the antigenic properties of the L. infantum Hsp70: design of synthetic peptides for specific serodiagnosis of human leishmaniasis
    • Quijada L., Requena J.M., Soto M., and Alonso C. Analysis of the antigenic properties of the L. infantum Hsp70: design of synthetic peptides for specific serodiagnosis of human leishmaniasis. Immunol Lett 63 3 (1998) 169-174
    • (1998) Immunol Lett , vol.63 , Issue.3 , pp. 169-174
    • Quijada, L.1    Requena, J.M.2    Soto, M.3    Alonso, C.4
  • 46
    • 0025346686 scopus 로고
    • Identification and characterisation of a Leishmania donovani antigen belonging to the 70-kDa heat-shock protein family
    • MacFarlane J., Blaxter M.L., Bishop R.P., Miles M.A., and Kelly J.M. Identification and characterisation of a Leishmania donovani antigen belonging to the 70-kDa heat-shock protein family. Eur J Biochem 190 2 (1990) 377-384
    • (1990) Eur J Biochem , vol.190 , Issue.2 , pp. 377-384
    • MacFarlane, J.1    Blaxter, M.L.2    Bishop, R.P.3    Miles, M.A.4    Kelly, J.M.5
  • 47
    • 0030730835 scopus 로고    scopus 로고
    • Association of Leishmania heat shock protein 83 antigen and immunoglobulin G4 antibody titers in Brazilian patients with diffuse cutaneous leishmaniasis
    • Skeiky Y.A., Benson D.R., Costa J.L., Badaro R., and Reed S.G. Association of Leishmania heat shock protein 83 antigen and immunoglobulin G4 antibody titers in Brazilian patients with diffuse cutaneous leishmaniasis. Infect Immun 65 12 (1997) 5368-5370
    • (1997) Infect Immun , vol.65 , Issue.12 , pp. 5368-5370
    • Skeiky, Y.A.1    Benson, D.R.2    Costa, J.L.3    Badaro, R.4    Reed, S.G.5
  • 48
    • 0036819236 scopus 로고    scopus 로고
    • The heat shock proteins, Hsp70 and Hsp83, of Leishmania infantum are mitogens for mouse B cells
    • Rico A.I., Girones N., Fresno M., Alonso C., and Requena J.M. The heat shock proteins, Hsp70 and Hsp83, of Leishmania infantum are mitogens for mouse B cells. Cell Stress Chaperones 7 4 (2002) 339-346
    • (2002) Cell Stress Chaperones , vol.7 , Issue.4 , pp. 339-346
    • Rico, A.I.1    Girones, N.2    Fresno, M.3    Alonso, C.4    Requena, J.M.5
  • 49
    • 0017234962 scopus 로고
    • Experimental Chagas' disease: protective activity in relation with subcellular fractions of the parasite
    • Segura E.L., Paulone I., Cerisola J., and Cappa S.M. Experimental Chagas' disease: protective activity in relation with subcellular fractions of the parasite. J Parasitol 62 1 (1976) 131-133
    • (1976) J Parasitol , vol.62 , Issue.1 , pp. 131-133
    • Segura, E.L.1    Paulone, I.2    Cerisola, J.3    Cappa, S.M.4
  • 50
    • 0017670474 scopus 로고
    • Antigens of the subcellular fractions of Trypanosoma cruzi. II. Flagellar and membrane fraction
    • Segura E.L., Vazquez C., Bronzina A., Campos J.M., Cerisola J.A., and Cappa S.M. Antigens of the subcellular fractions of Trypanosoma cruzi. II. Flagellar and membrane fraction. J Protozool 24 4 (1977) 540-543
    • (1977) J Protozool , vol.24 , Issue.4 , pp. 540-543
    • Segura, E.L.1    Vazquez, C.2    Bronzina, A.3    Campos, J.M.4    Cerisola, J.A.5    Cappa, S.M.6
  • 51
    • 0032497818 scopus 로고    scopus 로고
    • The expression of the Leishmania infantum KMP-11 protein is developmentally regulated and stage specific
    • Berberich C., Machado G., Morales G., Carrillo G., Jimenez-Ruiz A., and Alonso C. The expression of the Leishmania infantum KMP-11 protein is developmentally regulated and stage specific. Biochim Biophys Acta 1442 2-3 (1998) 230-237
    • (1998) Biochim Biophys Acta , vol.1442 , Issue.2-3 , pp. 230-237
    • Berberich, C.1    Machado, G.2    Morales, G.3    Carrillo, G.4    Jimenez-Ruiz, A.5    Alonso, C.6
  • 52
    • 0034214297 scopus 로고    scopus 로고
    • Evolutionarily conserved proteins as prominent immunogens during Leishmania infections
    • Requena J.M., Alonso C., and Soto M. Evolutionarily conserved proteins as prominent immunogens during Leishmania infections. Parasitol Today 16 6 (2000) 246-250
    • (2000) Parasitol Today , vol.16 , Issue.6 , pp. 246-250
    • Requena, J.M.1    Alonso, C.2    Soto, M.3
  • 53
    • 0027144786 scopus 로고    scopus 로고
    • Kemp M, Kurtzhals JA, Kharazmi A, Theander TG. Interferon-gamma and interleukin-4 in human Leishmania donovani infections. Immunol Cell Biol 1993;71(Pt 6):583-7.
    • Kemp M, Kurtzhals JA, Kharazmi A, Theander TG. Interferon-gamma and interleukin-4 in human Leishmania donovani infections. Immunol Cell Biol 1993;71(Pt 6):583-7.
  • 54
    • 0028999122 scopus 로고
    • Kinetoplastid membrane protein-11 (KMP-11) is differentially expressed during the life cycle of African trypanosomes and is found in a wide variety of kinetoplastid parasites
    • Stebeck C.E., Beecroft R.P., Singh B.N., Jardim A., Olafson R.W., Tuckey C., et al. Kinetoplastid membrane protein-11 (KMP-11) is differentially expressed during the life cycle of African trypanosomes and is found in a wide variety of kinetoplastid parasites. Mol Biochem Parasitol 71 1 (1995) 1-13
    • (1995) Mol Biochem Parasitol , vol.71 , Issue.1 , pp. 1-13
    • Stebeck, C.E.1    Beecroft, R.P.2    Singh, B.N.3    Jardim, A.4    Olafson, R.W.5    Tuckey, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.