N-Methyl d-Aspartate Receptor Antagonists Ketamine and MK-801 Induce Wake-Related Aberrant γ Oscillations in the Rat Neocortex

Biological Psychiatry

Volumn 63, Issue 8, 2008, Pages 730-735

  Pinault, Didier ^a  

^a INSERM   (France)

Author keywords

Apomorphine; d amphetamine; electrocorticogram; glutamate; neural synchrony; schizophrenia

Indexed keywords

APOMORPHINE; DEXAMPHETAMINE; DIZOCILPINE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHYSOSTIGMINE; SODIUM CHLORIDE;

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CORTICAL SYNCHRONIZATION; DOPAMINERGIC SYSTEM; ELECTROCORTICOGRAPHY; GAMMA RHYTHM; HALLUCINATION; MALE; NEOCORTEX; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR INTRINSIC ACTIVITY; SCHIZOPHRENIA; SCHIZOPHRENIFORM DISORDER; SINGLE DRUG DOSE; WAKEFULNESS;

EID: 40849105357     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2007.10.006     Document Type: Article

References (32)

1. Friston K.J. Dysfunctional connectivity in schizophrenia. World Psychiatry 1 (2002) 66-71
2. Tononi G., and Edelman G.M. Schizophrenia and the mechanisms of conscious integration. Brain Res Brain Res Rev 31 (2000) 391-400
3. Moghaddam B. Bringing order to the glutamate chaos in schizophrenia. Neuron 40 (2003) 881-884
4. Pilowsky L.S., Bressan R.A., Stone J.M., Erlandsson K., Mulligan R.S., Krystal J.H., et al. First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients. Mol Psychiatry 11 (2006) 118-119
5. Rujescu D., Bender A., Keck M., Hartmann A.M., Ohl F., Raeder H., et al. A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: Molecular, cellular, functional and behavioral abnormalities. Biol Psychiatry 59 (2006) 721-729
6. Woo T.U., Walsh J.P., and Benes F.M. Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder. Arch Gen Psychiatry 61 (2004) 649-657
7. Adler C.M., Goldberg T.E., Malhotra A.K., Pickar D., and Breier A. Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers. Biol Psychiatry 43 (1998) 811-816
8. Hetem L.A., Danion J.M., Diemunsch P., and Brandt C. Effect of a subanesthetic dose of ketamine on memory and conscious awareness in healthy volunteers. Psychopharmacology 152 (2000) 283-288 (Berl)
9. Krystal J.H., Karper L.P., Seibyl J.P., Freeman G.K., Delaney R., Bremner J.D., et al. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 51 (1994) 199-214
10. Newcomer J.W., Farber N.B., Jevtovic-Todorovic V., Selke G., Melson A.K., Hershey T., et al. Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis. Neuropsychopharmacology 20 (1999) 106-118
11. Joliot M., Ribary U., and Llinas R. Human oscillatory brain activity near 40 Hz coexists with cognitive temporal binding. Proc Natl Acad Sci U S A 91 (1994) 11748-11751
12. Spencer K.M., Nestor P.G., Niznikiewicz M.A., Salisbury D.F., Shenton M.E., and McCarley R.W. Abnormal neural synchrony in schizophrenia. J Neurosci 23 (2003) 7407-7411
13. Kapur S., and Seeman P. NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2) receptors-implications for models of schizophrenia. Mol Psychiatry 7 (2002) 837-844
14. Olney J.W., Newcomer J.W., and Farber N.B. NMDA receptor hypofunction model of schizophrenia. J Psychiatr Res 33 (1999) 523-533
15. Tomitaka S., Tomitaka M., Tolliver B.K., and Sharp F.R. Bilateral blockade of NMDA receptors in anterior thalamus by dizocilpine (MK-801) injures pyramidal neurons in rat retrosplenial cortex. Eur J Neurosci 12 (2000) 1420-1430
16. Becker A., Peters B., Schroeder H., Mann T., Huether G., and Grecksch G. Ketamine-induced changes in rat behaviour: A possible animal model of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 27 (2003) 687-700
17. Hunt M.J., Raynaud B., and Garcia R. Ketamine dose-dependently induces high-frequency oscillations in the nucleus accumbens in freely moving rats. Biol Psychiatry 60 (2006) 1206-1214
18. Skuza G., and Rogoz Z. The synergistic effect of selective sigma receptor agonists and uncompetitive NMDA receptor antagonists in the forced swim test in rats. J Physiol Pharmacol 57 (2006) 217-229
19. Grunze H.C., Rainnie D.G., Hasselmo M.E., Barkai E., Hearn E.F., McCarley R.W., et al. NMDA-dependent modulation of CA1 local circuit inhibition. J Neurosci 16 (1996) 2034-2043
20. Bartos M., Vida I., and Jonas P. Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat Rev Neurosci 8 (2007) 45-56
21. Lewis D.A., Hashimoto T., and Volk D.W. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci 6 (2005) 312-324
22. Abekawa T., Ito K., Nakagawa S., and Koyama T. Prenatal exposure to an NMDA receptor antagonist, MK-801 reduces density of parvalbumin-immunoreactive GABAergic neurons in the medial prefrontal cortex and enhances phencyclidine-induced hyperlocomotion but not behavioral sensitization to methamphetamine in postpubertal rats. Psychopharmacology 192 (2007) 303-316 (Berl)
23. Cunningham M.O., Hunt J., Middleton S., LeBeau F.E., Gillies M.J., Davies C.H., et al. Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness. J Neurosci 26 (2006) 2767-2776
24. Keilhoff G., Becker A., Grecksch G., Wolf G., and Bernstein H.G. Repeated application of ketamine to rats induces changes in the hippocampal expression of parvalbumin, neuronal nitric oxide synthase and cFOS similar to those found in human schizophrenia. Neuroscience 126 (2004) 591-598
25. Olney J.W., and Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry 52 (1995) 998-1007
26. Jackson M.E., Homayoun H., and Moghaddam B. NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. Proc Natl Acad Sci U S A 101 (2004) 8467-8472
27. Suzuki Y., Jodo E., Takeuchi S., Niwa S., and Kayama Y. Acute administration of phencyclidine induces tonic activation of medial prefrontal cortex neurons in freely moving rats. Neuroscience 114 (2002) 769-779
28. Behrendt R.P. Hallucinations: Synchronisation of thalamocortical gamma oscillations underconstrained by sensory input. Conscious Cogn 12 (2003) 413-451
29. Herrmann C.S., and Demiralp T. Human EEG gamma oscillations in neuropsychiatric disorders. Clin Neurophysiol 116 (2005) 2719-2733
30. Lee K.H., Williams L.M., Haig A., and Gordon E. "Gamma (40 Hz) phase synchronicity" and symptom dimensions in schizophrenia. Cognit Neuropsychiatry 8 (2003) 57-71
31. Spencer K.M., Nestor P.G., Perlmutter R., Niznikiewicz M.A., Klump M.C., Frumin M., et al. Neural synchrony indexes disordered perception and cognition in schizophrenia. Proc Natl Acad Sci U S A 101 (2004) 17288-17293
32. Baldeweg T., Spence S., Hirsch S.R., and Gruzelier J. Gamma-band electroencephalographic oscillations in a patient with somatic hallucinations. Lancet 352 (1998) 620-621