메뉴 건너뛰기




Volumn 93, Issue 3, 2008, Pages 1020-1029

Protein kinase A-independent inhibition of proliferation and induction of apoptosis in human thyroid cancer cells by 8-Cl-adenosine

Author keywords

[No Author keywords available]

Indexed keywords

8 CL ADENOSINE; 8 CL CYCLIC AMP; ANTINEOPLASTIC AGENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOBUTYLMETHYLXANTHINE; UNCLASSIFIED DRUG;

EID: 40849104803     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-2331     Document Type: Article
Times cited : (23)

References (40)
  • 1
    • 13444292976 scopus 로고    scopus 로고
    • Definition of poorly differentiated carcinoma of the thyroid: The Japanese experience
    • Sakamoto A 2004 Definition of poorly differentiated carcinoma of the thyroid: the Japanese experience. Endocr Pathol 15:307-311
    • (2004) Endocr Pathol , vol.15 , pp. 307-311
    • Sakamoto, A.1
  • 2
    • 13444311710 scopus 로고    scopus 로고
    • Genetic alterations involved in the transition from well-differentiated to poorly differentiated and anaplastic thyroid carcinomas
    • Nikiforov YE 2004 Genetic alterations involved in the transition from well-differentiated to poorly differentiated and anaplastic thyroid carcinomas. Endocr Pathol 15:319-327
    • (2004) Endocr Pathol , vol.15 , pp. 319-327
    • Nikiforov, Y.E.1
  • 4
    • 33644866495 scopus 로고    scopus 로고
    • Thyroid tumors: Histological classification and genetic factors involved in the development of thyroid cancer
    • Liska J, Altanerova V, Galbavy S, Stvrtina S, Brtko J 2005 Thyroid tumors: histological classification and genetic factors involved in the development of thyroid cancer. Endocr Res 39:73-83
    • (2005) Endocr Res , vol.39 , pp. 73-83
    • Liska, J.1    Altanerova, V.2    Galbavy, S.3    Stvrtina, S.4    Brtko, J.5
  • 5
    • 0031752682 scopus 로고    scopus 로고
    • Anaplastic thyroid carcinoma: Behavior, biology and therapeutic approaches
    • Ain KB 1998 Anaplastic thyroid carcinoma: behavior, biology and therapeutic approaches. Thyroid 8:715-726
    • (1998) Thyroid , vol.8 , pp. 715-726
    • Ain, K.B.1
  • 6
    • 0036293732 scopus 로고    scopus 로고
    • Protein kinase A signaling: "cross talk" with other pathways in endocrine cells
    • Robinson-White A, Stratakis CA 2002 Protein kinase A signaling: "cross talk" with other pathways in endocrine cells. Ann NY Acad Sci 968:256-270
    • (2002) Ann NY Acad Sci , vol.968 , pp. 256-270
    • Robinson-White, A.1    Stratakis, C.A.2
  • 9
    • 0025810398 scopus 로고
    • Cyclic nucleotide-dependent protein kinase
    • Scott JD 1991 Cyclic nucleotide-dependent protein kinase. Pharmacol Ther 50:123-145
    • (1991) Pharmacol Ther , vol.50 , pp. 123-145
    • Scott, J.D.1
  • 10
    • 33751301602 scopus 로고    scopus 로고
    • PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes
    • Robinson-White AJ, Leitner WW, Aleem E, Kaldis P, Bossis I, Stratakis CA 2006 PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes. Cancer Res 66:10603-10612
    • (2006) Cancer Res , vol.66 , pp. 10603-10612
    • Robinson-White, A.J.1    Leitner, W.W.2    Aleem, E.3    Kaldis, P.4    Bossis, I.5    Stratakis, C.A.6
  • 12
    • 0023714205 scopus 로고
    • Selective modulation of protein kinase isozymes by the site-selective analog 8-chloroadensoine 3′,5′-cyclic monophosphate provides a biological means for control of human colon cancer cell growth
    • Ally S, Tortora G, Clair T, Grieco D, Merlo G, Katsaros D, Ogreid D, Doskeland SO, Jahnsen T, Cho-Chung YS 1988 Selective modulation of protein kinase isozymes by the site-selective analog 8-chloroadensoine 3′,5′-cyclic monophosphate provides a biological means for control of human colon cancer cell growth. Proc Natl Acad Sci USA 85:6319-6322
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6319-6322
    • Ally, S.1    Tortora, G.2    Clair, T.3    Grieco, D.4    Merlo, G.5    Katsaros, D.6    Ogreid, D.7    Doskeland, S.O.8    Jahnsen, T.9    Cho-Chung, Y.S.10
  • 13
    • 0027456590 scopus 로고
    • 8-Cl-cAMP induces truncation and downregulation of the RI α-subunit and up-regulation of the RII β-subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells
    • Rohlff C, Clair T, Cho-Chung YS 1993 8-Cl-cAMP induces truncation and downregulation of the RI α-subunit and up-regulation of the RII β-subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells. J Biol Chem 268:5774-5782
    • (1993) J Biol Chem , vol.268 , pp. 5774-5782
    • Rohlff, C.1    Clair, T.2    Cho-Chung, Y.S.3
  • 15
    • 0035878796 scopus 로고    scopus 로고
    • 8-Chloro-cAMP and 8-chloro-adenosine act by the same mechanism in multiple myeloma cells
    • Gandhi V, Ayers M, Halgren RG, Krett NL, Newman RA, Rosen ST 2001 8-Chloro-cAMP and 8-chloro-adenosine act by the same mechanism in multiple myeloma cells. Cancer Res 61:5474-5479
    • (2001) Cancer Res , vol.61 , pp. 5474-5479
    • Gandhi, V.1    Ayers, M.2    Halgren, R.G.3    Krett, N.L.4    Newman, R.A.5    Rosen, S.T.6
  • 16
    • 0031021259 scopus 로고    scopus 로고
    • The antiproliferative effect of 8-chloro-adenosine, an active metabolite of 8-chloro-cyclic adenosine monophosphate and disturbances in nucleic acid synthesis and cell cycle kinetics
    • Langeveld CH, Jongenelen CAM, Theeuwes JWM, Baak JPA, Heimans JJ, Stoff JC, Peters GJ 1997 The antiproliferative effect of 8-chloro-adenosine, an active metabolite of 8-chloro-cyclic adenosine monophosphate and disturbances in nucleic acid synthesis and cell cycle kinetics. Biochem Pharm 53:141-148
    • (1997) Biochem Pharm , vol.53 , pp. 141-148
    • Langeveld, C.H.1    Jongenelen, C.A.M.2    Theeuwes, J.W.M.3    Baak, J.P.A.4    Heimans, J.J.5    Stoff, J.C.6    Peters, G.J.7
  • 17
    • 0026764144 scopus 로고
    • Growth inhibition of human glioma cells induced by 8-chloroadenosine, an active metabolite of 8-chloro adenosine 3′:5′-monophosphate
    • Langeveld CH, Jongenelen CAM, Heimans JJ, Stoff JC 1992 Growth inhibition of human glioma cells induced by 8-chloroadenosine, an active metabolite of 8-chloro adenosine 3′:5′-monophosphate. Cancer Res 52:3994-3999
    • (1992) Cancer Res , vol.52 , pp. 3994-3999
    • Langeveld, C.H.1    Jongenelen, C.A.M.2    Heimans, J.J.3    Stoff, J.C.4
  • 18
    • 0035206293 scopus 로고    scopus 로고
    • 8-Cl-adenosine is an active metabolite of 8-Cl-cAMP responsible for its in vitro antiproliferative effects on CHO mutants hypersensitive to cytostatic drugs
    • Robbins SK, Houlbrook S, Priddle JD, Harris AL 2001 8-Cl-adenosine is an active metabolite of 8-Cl-cAMP responsible for its in vitro antiproliferative effects on CHO mutants hypersensitive to cytostatic drugs. Cancer Chemother Pharmacol 48:451-458
    • (2001) Cancer Chemother Pharmacol , vol.48 , pp. 451-458
    • Robbins, S.K.1    Houlbrook, S.2    Priddle, J.D.3    Harris, A.L.4
  • 19
    • 0032532354 scopus 로고    scopus 로고
    • 8 Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine
    • Halgren RG, Traynor AE, Pillay S, Zell JL, Heller KF, Krett NL, Rosen ST 1998 8 Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine. Blood 92:2893-2898
    • (1998) Blood , vol.92 , pp. 2893-2898
    • Halgren, R.G.1    Traynor, A.E.2    Pillay, S.3    Zell, J.L.4    Heller, K.F.5    Krett, N.L.6    Rosen, S.T.7
  • 20
    • 0018288468 scopus 로고
    • Maximum activities, properties and distribution of 5′-nucleotidase, adenosine kinase and adenosine deaminase in rat and human brain
    • Phillips E, Newsholme EA 1979 Maximum activities, properties and distribution of 5′-nucleotidase, adenosine kinase and adenosine deaminase in rat and human brain. J Neurochem 33:553-558
    • (1979) J Neurochem , vol.33 , pp. 553-558
    • Phillips, E.1    Newsholme, E.A.2
  • 21
    • 0345275863 scopus 로고    scopus 로고
    • RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells
    • Stellrecht CM, Rodriguez Jr CO, Ayres M, Gandhi V 2003 RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells. Cancer Res 63:7968-7974
    • (2003) Cancer Res , vol.63 , pp. 7968-7974
    • Stellrecht, C.M.1    Rodriguez Jr, C.O.2    Ayres, M.3    Gandhi, V.4
  • 23
    • 0031960074 scopus 로고    scopus 로고
    • 8 Chloro-adenosine induced apoptosis in various human tumor cell lines]
    • Zhang S, Zheng D, Liu S 1998 [8 Chloro-adenosine induced apoptosis in various human tumor cell lines]. Zhonghua Zhong Liu Za Zhi (Chinese) 20:88-89
    • (1998) Zhonghua Zhong Liu Za Zhi (Chinese) , vol.20 , pp. 88-89
    • Zhang, S.1    Zheng, D.2    Liu, S.3
  • 24
    • 0035069874 scopus 로고    scopus 로고
    • 8-Cl-adenosine mediated cytotoxicity and sensitization of T-lymphoblast leukemia cells to TNFα-induced apoptosis is via inactivation of NF-kB
    • Yin Y, Allen PD, Jia I, Kelsey SM, Newland AC 2001 8-Cl-adenosine mediated cytotoxicity and sensitization of T-lymphoblast leukemia cells to TNFα-induced apoptosis is via inactivation of NF-kB. Leukemia Res 25:423-431
    • (2001) Leukemia Res , vol.25 , pp. 423-431
    • Yin, Y.1    Allen, P.D.2    Jia, I.3    Kelsey, S.M.4    Newland, A.C.5
  • 25
    • 0035674541 scopus 로고    scopus 로고
    • 8 Cl-adenosine induces growth arrest without differentiation of primary mouse epidermal keratinocytes
    • Dransfield DT, Griner RD, Ray S, Keskintepe M, Bollag WB 2001 8 Cl-adenosine induces growth arrest without differentiation of primary mouse epidermal keratinocytes. J Invest Dermatol 117:1588-1593
    • (2001) J Invest Dermatol , vol.117 , pp. 1588-1593
    • Dransfield, D.T.1    Griner, R.D.2    Ray, S.3    Keskintepe, M.4    Bollag, W.B.5
  • 28
    • 0028942106 scopus 로고
    • Human neutrophils lose their surface FcγRIII and acquire annexin V binding sites during apoptosis in vitro
    • Homburg CH, deHass M, von dem Borne AE, Verhoeven AJ, Reutelingsperger CP, Roo SD 1995 Human neutrophils lose their surface FcγRIII and acquire annexin V binding sites during apoptosis in vitro. Blood 85:532-540
    • (1995) Blood , vol.85 , pp. 532-540
    • Homburg, C.H.1    deHass, M.2    von dem3    Borne, A.E.4    Verhoeven, A.J.5    Reutelingsperger, C.P.6    Roo, S.D.7
  • 31
    • 0036301305 scopus 로고    scopus 로고
    • Anti-proliferative effects of 8-Chloro-cAMP and other cAMP analogs are unrelated to their effects on protein kinase A regulatory subunit expression
    • Lamb D, Steinberg RA 2002 Anti-proliferative effects of 8-Chloro-cAMP and other cAMP analogs are unrelated to their effects on protein kinase A regulatory subunit expression. J Cell Physiol 192:216-224
    • (2002) J Cell Physiol , vol.192 , pp. 216-224
    • Lamb, D.1    Steinberg, R.A.2
  • 32
    • 0026782535 scopus 로고
    • Inhibition of colon tumor cell growth by 8-chloro-cAMP is dependent upon its conversion to 8-chloro-adenosine
    • Taylor CW, Yeoman LC 1992 Inhibition of colon tumor cell growth by 8-chloro-cAMP is dependent upon its conversion to 8-chloro-adenosine. Anticancer Drugs 3:485-491
    • (1992) Anticancer Drugs , vol.3 , pp. 485-491
    • Taylor, C.W.1    Yeoman, L.C.2
  • 34
    • 0028971416 scopus 로고
    • 3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis. Tetrazolium assays provide markedly enhanced sensitivity
    • 3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis. Tetrazolium assays provide markedly enhanced sensitivity. J Immunol Methods 187:85-93
    • (1995) J Immunol Methods , vol.187 , pp. 85-93
    • Gieni, R.S.1    Li, Y.2    HayGlass, K.T.3
  • 35
    • 0027509430 scopus 로고
    • 8-Chloroadenosine mediates 8-chloro-cyclic AMP-induced down-regulation of cyclic AMP-dependent protein kinase in normal and neoplastic mouse lung epithelial cells by a cyclic AMP-independent mechanism
    • Lange-Carter CA, Vuillequez JJ, Malkinson AM 1993 8-Chloroadenosine mediates 8-chloro-cyclic AMP-induced down-regulation of cyclic AMP-dependent protein kinase in normal and neoplastic mouse lung epithelial cells by a cyclic AMP-independent mechanism. Cancer Res 53:393-400
    • (1993) Cancer Res , vol.53 , pp. 393-400
    • Lange-Carter, C.A.1    Vuillequez, J.J.2    Malkinson, A.M.3
  • 36
    • 0027490967 scopus 로고
    • Proliferation of nontransformed cells is inhibited by adenosine metabolite of but not by parental 8-Cl-cyclic AMP
    • Han Z, Chatterjee D, Wyche JH 1993 Proliferation of nontransformed cells is inhibited by adenosine metabolite of but not by parental 8-Cl-cyclic AMP. J Pharmacol Exp Ther 265:790-794
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 790-794
    • Han, Z.1    Chatterjee, D.2    Wyche, J.H.3
  • 37
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expressiononearly apoptotic cells using fluorescein labeled annexin V
    • Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C 1995 A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expressiononearly apoptotic cells using fluorescein labeled annexin V. J Immunol Methods 184:39-51
    • (1995) J Immunol Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 38
    • 0023154076 scopus 로고
    • Characterization of adenosine receptors in the PC12 pheochromocytoma cell line using radioligand binding: Evidence for A-2 selectivity
    • Williams M, Abreu M, Jarvis MF, Noronha-Blob L 1987 Characterization of adenosine receptors in the PC12 pheochromocytoma cell line using radioligand binding: evidence for A-2 selectivity. J Neurochem 48:498-502
    • (1987) J Neurochem , vol.48 , pp. 498-502
    • Williams, M.1    Abreu, M.2    Jarvis, M.F.3    Noronha-Blob, L.4
  • 39
    • 0029002725 scopus 로고
    • Growth inhibition by 8-chlorocyclic AMP of human HT29 colorectal and ZR-75-1 breast carcinoma xenographs is associated with selective modulation of protein kinaseA isozymes
    • Ramage AD, Langdon SP, Ritchie AA, Burn DJ, Miller WR 1995 Growth inhibition by 8-chlorocyclic AMP of human HT29 colorectal and ZR-75-1 breast carcinoma xenographs is associated with selective modulation of protein kinaseA isozymes. Eur J Cancer 31A:969-973
    • (1995) Eur J Cancer , vol.31 A , pp. 969-973
    • Ramage, A.D.1    Langdon, S.P.2    Ritchie, A.A.3    Burn, D.J.4    Miller, W.R.5
  • 40
    • 20044380158 scopus 로고    scopus 로고
    • Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: Regulation of p27kip1 expression and localization
    • Motti ML, Califano D, Troncone G, De Marco C, Migliaccio I, Palmieri E, Pezzullo L, Palombini L, Fusco A, Viglietto G 2005 Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localization. Am J Pathol 166:737-749
    • (2005) Am J Pathol , vol.166 , pp. 737-749
    • Motti, M.L.1    Califano, D.2    Troncone, G.3    De Marco, C.4    Migliaccio, I.5    Palmieri, E.6    Pezzullo, L.7    Palombini, L.8    Fusco, A.9    Viglietto, G.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.