The antiproliferative effect of 8-chloro-adenosine, an active metabolite of 8-chloro-cyclic adenosine monophosphate, and disturbances in nucleic acid synthesis and cell cycle kinetics

Biochemical Pharmacology

Volumn 53, Issue 2, 1997, Pages 141-148

  Langeveld, Cornelis H ^a   Jongenelen, Cornelis A M ^a   Theeuwes, Johannes Wilhelmus M ^b   Baak, Johannes P A ^b   Heimans, Johannes J ^a   Stoof, Johannes C ^a   Peters, Godefridus J ^b  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

8 chloro adenosine; 8 chloro cyclic AMP; cell cycle kinetics; DNA incorporation; human glioma cells; RNA incorporation

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; 8 CHLOROADENOSINE; 8 CHLOROADENOSINE 3',5' PHOSPHATE; ADENOSINE DEAMINASE; DRUG METABOLITE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; CELL PROLIFERATION; DNA SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NUCLEIC ACID SYNTHESIS; PRIORITY JOURNAL; RNA SYNTHESIS;

2-CHLOROADENOSINE; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL DIVISION; DNA; FLOW CYTOMETRY; HUMANS; RNA; TUMOR CELLS, CULTURED;

EID: 0031021259     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00593-X     Document Type: Article

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