Enhanced immunogenicity of multiple-epitopes of foot-and-mouth disease virus fused with porcine interferon α in mice and protective efficacy in guinea pigs and swine

Journal of Virological Methods

Volumn 149, Issue 1, 2008, Pages 144-152

  Du, Yijun ^a   Li, Yufeng ^a   He, Hairong ^b   Qi, Jing ^c   Jiang, Wenming ^a   Wang, Xinglong ^a   Tang, Bo ^a   Cao, Jun ^a   Wang, Xianwei ^a   Jiang, Ping ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

^b Qianyuanhao Biological Co Ltd   (China)

^c SHANDONG PEANUT RESEARCH INSTITUTE   (China)

Author keywords

Epitope; Foot and mouth disease virus; Interferon ; Recombinant adenovirus

Indexed keywords

ALPHA INTERFERON; AMINO ACID; EPITOPE; FOOT AND MOUTH DISEASE VACCINE; GAMMA INTERFERON; PROTEIN VP1;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GUINEA PIG; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNOGENICITY; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SWINE; TH1 CELL; TH2 CELL; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; ANTIBODIES, VIRAL; CAPSID PROTEINS; CELL LINE; CYTOKINES; EPITOPES; FEMALE; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; GUINEA PIGS; HUMANS; INTERFERON-ALPHA; MICE; RECOMBINANT FUSION PROTEINS; SWINE; SWINE DISEASES; T-LYMPHOCYTES, HELPER-INDUCER; VACCINES, SYNTHETIC; VIRAL VACCINES;

ADENOVIRIDAE; ANIMALIA; CAVIA; FOOT-AND-MOUTH DISEASE VIRUS; MUS; SUIDAE; SUS;

EID: 40849102257     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2007.12.018     Document Type: Article

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