Association of MYO9B haplotype with type 1 diabetes

Human Immunology

Volumn 69, Issue 2, 2008, Pages 112-115

  Santiago, Jose Luis ^a   Martínez, Alfonso ^a   Núñez, Concepción ^a   de la Calle, Hermenegildo ^b   Fernández Arquero, Miguel ^a   de la Concha, Emilio G ^a   Urcelay, E ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^b HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Genetic susceptibility; MYO9B polymorphisms; Type 1 diabetes

Indexed keywords

MYOSIN; MYOSIN 9B; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA POLYMORPHISM; ETHNIC DIFFERENCE; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; POPULATION GENETIC PARAMETERS; PRIORITY JOURNAL; RISK FACTOR;

AUTOIMMUNE DISEASES; DIABETES MELLITUS, TYPE 1; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HLA ANTIGENS; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MYOSINS; POLYMORPHISM, GENETIC; RISK FACTORS; SPAIN;

EID: 40849097522     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2008.01.003     Document Type: Article

References (30)

1. Hirschhorn J.N. Genetic epidemiology of type 1 diabetes. Pediatr Diabetes 4 (2003) 87
2. Todd J.A., Walker N.M., Cooper J.D., Smyth D.J., Downes K., Plagnol V., et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 39 (2007) 857-864
3. Green A., and Patterson C.C. Trends in the incidence of childhood-onset diabetes in Europe 1989-1998. Diabetologia 44 Suppl 3 (2001) B3
4. Redondo M.J., Yu L., Hawa M., Mackenzie T., Pyke D.A., and Eisenbarth G.S. Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States. Diabetologia 44 (2001) 354
5. Carratu R., Secondulfo M., de Magistris L., Iafusco D., Urio A., and Carbone M.G. Altered intestinal permeability to mannitol in diabetes mellitus type I. J Pediatr Gastroenterol Nutr 28 (1999) 264
6. Damci T., Nuhoglu I., Devranoglu G., Osar Z., Demir M., and Ilkova H. Increased intestinal permeability as a cause of fluctuating postprandial blood glucose levels in type 1 diabetic patients. Eur J Clin Invest 33 (2003) 397
7. Kuitunen M., Saukkonen T., Ilonen J., Akerblom H.K., and Savilahti E. Intestinal permeability to mannitol and lactulose in children with type 1 diabetes with the HLA-DQB1*02 allele. Autoimmunity 35 (2002) 365
8. Secondulfo M., Iafusco D., Carratu R., deMagistris L., Sapone A., Generoso M., et al. Ultrastructural mucosal alterations and increased intestinal permeability in non-celiac, type I diabetic patients. Dig Liver Dis 36 (2004) 35
9. Hawkins B.T., Lundeen T.F., Norwood K.M., Brooks H.L., and Egleton R.D. Increased blood-brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases. Diabetologia 50 (2007) 202
10. Meddings J.B., Jarand J., Urbanski S.J., Hardin J., and Gall D.G. Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat. Am J Physiol 276 (1999) G951
11. Neu J., Reverte C.M., Mackey A.D., Liboni K., Tuhacek-Tenace L.M., Hatch M., et al. Changes in intestinal morphology and permeability in the biobreeding rat before the onset of type 1 diabetes. J Pediatr Gastroenterol Nutr 40 (2005) 589
12. Sapone A., de Magistris L., Pietzak M., Clemente M.G., Tripathi A., Cucca F., et al. Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives. Diabetes 55 (2006) 1443
13. Monsuur A.J., de Bakker P.I., Alizadeh B.Z., Zhernakova A., Bevova M.R., Strengman E., et al. Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat Genet 37 (2005) 1341
14. Nuñez C., Oliver J., Mendoza J.L., Gómez-García M., Piñero A., Taxonera C., et al. MYO9B polymorphisms in patients with inflammatory bowel disease. Gut 56 (2007) 1321-1322
15. van Bodegraven A.A., Curley C.R., Hunt K.A., Monsuur A.J., Linskens R.K., Onnie C.M., et al. Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology 131 (2006) 1768
16. Latiano A, Palmieri O, Valvano MR, D'Inca R, Caprilli R, Cucchiara S, et al. Association of myo9b gene in Italian patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2007 17 Oct [Epub ahead of print].
17. Sanchez E., Alizadeh B.Z., Valdigem G., Ortego-Centeno N., Jimenez-Alonso J., et al. MYO9B gene polymorphisms are associated with autoimmune diseases in Spanish population. Hum Immunol 68 (2007) 610
18. Wirth J.A., Jensen K.A., Post P.L., Bement W.M., and Mooseker M.S. Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail. J Cell Sci 109 (1996) 653
19. Matter K., Aijaz S., Tsapara A., and Balda M.S. Mammalian tight junctions in the regulation of epithelial differentiation and proliferation. Curr Opin Cell Biol 17 (2005) 453
20. Concannon P., Gogolin-Ewens K.J., Hinds D.A., Wapelhorst B., Morrison V.A., Stirling B., et al. A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus. Nat Genet 19 (1998) 292
21. Mein C.A., Esposito L., Dunn M.G., Johnson G.C., Timms A.E., Goy J.V., et al. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat Genet 19 (1998) 297
22. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 20 (1997) 1183
23. Schneider S., and Excoffier L. Arlequin: A software for population genetics data analysis (2000), University of Geneva, Geneva
24. Nunez C., Marquez A., Varade J., Martinez A., Polanco I., Maluenda C., et al. No evidence of association of the MYO9B polymorphisms with celiac disease in the Spanish population. Tissue Antigens 68 (2006) 489
25. Ahmad T., Armuzzi A., Bunce M., Mulcahy-Hawes K., Marshall S.E., Orchard T.R., et al. The molecular classification of the clinical manifestations of Crohn's disease. Gastroenterology 122 (2002) 854
26. Noble J.A., Valdes A.M., Cook M., Klitz W., Thomson G., and Erlich H.A. The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families. Am J Hum Genet 59 (1996) 1134
27. Kimchi-Sarfaty C., Oh J.M., Kim I.W., Sauna Z.E., Calcagno A.M., Ambudkar S.V., et al. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 315 (2007) 525
28. Bosi E., Molteni L., Radaelli M.G., Folini L., Fermo I., Bazzigaluppi E., et al. Increased intestinal permeability precedes clinical onset of type 1 diabetes. Diabetologia 49 (2006) 2824
29. Antonetti D.A., Barber A.J., Khin S., Lieth E., Tarbell J.M., and Gardner T.W. Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group. Diabetes 47 (1998) 1953
30. Chehade J.M., Haas M.J., and Mooradian A.D. Diabetes-related changes in rat cerebral occludin and zonula occludens-1 (ZO-1) expression. Neurochem Res 27 (2002) 249