Viral vector-mediated 12/15-lipoxygenase overexpression in vascular smooth muscle cells enhances inflammatory gene expression and migration

Journal of Vascular Research

Volumn 45, Issue 2, 2008, Pages 132-142

  Dwarakanath, Roopashree S ^a   Sahar, Saurabh ^a   Lanting, Linda ^a   Wang, Nanping ^c   Stemerman, Michael B ^b   Natarajan, Rama ^a   Reddy, Marpadga A ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

12 15 Lipoxygenase; Adenoviruses; Atherosclerosis; Baculoviruses; Diabetes; Inflammatory genes; Nuclear factor B; Vascular smooth muscle cells; Viral vectors

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ADENOVIRUS VECTOR; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; BACULOVIRUS VECTOR; GREEN FLUORESCENT PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; ALOX15 PROTEIN, MOUSE; ANTIOXIDANT; AUTACOID; I KAPPA B; MULTIENZYME COMPLEX; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE; ADENOVIRUS; ANIMAL; BACULOVIRUS; CELL CULTURE; CELL MOTION; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; INFLAMMATION; METABOLISM; MOUSE; MUTATION; PATHOLOGY; RNA INTERFERENCE; SMOOTH MUSCLE FIBER; UPREGULATION;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ADENOVIRIDAE; ANIMALS; ANTIOXIDANTS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; BACULOVIRIDAE; CELL MOVEMENT; CELLS, CULTURED; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC VECTORS; HUMANS; I-KAPPA B PROTEINS; INFLAMMATION; INFLAMMATION MEDIATORS; MICE; MULTIENZYME COMPLEXES; MUSCLE, SMOOTH, VASCULAR; MUTATION; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR RELA; TRANSDUCTION, GENETIC; UP-REGULATION;

EID: 40749156301     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000109966     Document Type: Article

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