The Brugada Syndrome**Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.

Journal of the American College of Cardiology

Volumn 51, Issue 12, 2008, Pages 1176-1180

  Chen, Peng Sheng ^a   Priori, Silvia G ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AJMALINE; FLECAINIDE; ISOPRENALINE; PROCAINAMIDE; PROTEIN SCN5A; QUINIDINE; QUINIDINE ACID SULFATE; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ARRHYTHMOGENESIS; BRUGADA SYNDROME; CALCIUM CURRENT; CIRCADIAN RHYTHM; CLINICAL FEATURE; DEFIBRILLATOR; EDITORIAL; ELECTROCARDIOGRAM; ELECTROPHYSIOLOGY; GENE MUTATION; GENETIC DISORDER; HEART ARREST; HEART FUNCTION TEST; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE FIBRILLATION; HUMAN; NERVE CONDUCTION; P WAVE; PHENOTYPE; PRACTICE GUIDELINE; PRIORITY JOURNAL; QT INTERVAL; SODIUM CURRENT; ST SEGMENT ELEVATION; SUDDEN DEATH; SYMPATHETIC NERVE; SYNCOPE; T WAVE; VAGUS NERVE; ELECTROCARDIOGRAPHY; ENDOCARDIUM; GENETICS; HEART ATRIUM FIBRILLATION; NOTE; PATHOPHYSIOLOGY; PERICARDIUM; PREVALENCE;

ATRIAL FIBRILLATION; BRUGADA SYNDROME; ELECTROCARDIOGRAPHY; ENDOCARDIUM; HUMANS; PERICARDIUM; PREVALENCE; VENTRICULAR FIBRILLATION;

EID: 40749121331     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2007.12.006     Document Type: Editorial

References (46)

1. Brugada P., and Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. J Am Coll Cardiol 20 (1992) 1391-1396
2. Gang E.S., Priori S.S., and Chen P.S. Short coupled premature ventricular contraction initiating ventricular fibrillation in a patient with Brugada syndrome. J Cardiovasc Electrophysiol 15 (2004) 837
3. Hayashi M., Takatsuki S., Maison-Blanche P., et al. Ventricular repolarization restitution properties in patients exhibiting type 1 Brugada electrocardiogram with and without inducible ventricular fibrillation. J Am Coll Cardiol 51 (2008) 1162-1168
4. Kusano K.F., Taniyama M., Nakamura K., et al. Atrial fibrillation in patients with Brugada syndrome: relationships of gene mutation, electrophysiology, and clinical backgrounds. J Am Coll Cardiol 51 (2008) 1169-1175
5. Nagase S., Kusano K.F., Morita H., et al. Longer repolarization in the epicardium at the right ventricular outflow tract causes type 1 electrocardiogram in patients with Brugada syndrome. J Am Coll Cardiol 51 (2008) 1154-1161
6. Nademanee K., Veerakul G., Nimmannit S., et al. Arrhythmogenic marker for the sudden unexplained death syndrome in Thai men. Circulation 96 (1997) 2595-2600
7. Kirschner R.H., Eckner F.A.O., and Baron R.C. The cardiac pathology of sudden, unexplained nocturnal death in Southeast Asian refugees. JAMA 256 (1986) 2700-2705
8. Matsuo K., Akahoshi M., Nakashima E., et al. The prevalence, incidence and prognostic value of the Brugada-type electrocardiogram: a population-based study of four decades. J Am Coll Cardiol 38 (2001) 765-770
9. Miyasaka Y., Tsuji H., Yamada K., et al. Prevalence and mortality of the Brugada-type electrocardiogram in one city in Japan. J Am Coll Cardiol 38 (2001) 771-774
10. Priori S.G., Napolitano C., Gasparini M., et al. Clinical and genetic heterogeneity of right bundle branch block and ST-segment elevation syndrome: a prospective evaluation of 52 families. Circulation 102 (2000) 2509-2515
11. Morita H., Kusano-Fukushima K., Nagase S., et al. Atrial fibrillation and atrial vulnerability in patients with Brugada syndrome. J Am Coll Cardiol 40 (2002) 1437-1444
12. Chen Q., Kirsch G.E., Zhang D., et al. Genetic basis and molecular mechanism for idiopathic ventricular fibrillation. Nature 392 (1998) 293-296
13. Antzelevitch C. Genetic basis of Brugada syndrome. Heart Rhythm 4 (2007) 756-757
14. Mohler P.J., Rivolta I., Napolitano C., et al. Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes. Proc Natl Acad Sci U S A 101 (2004) 17533-17538
15. London B., Michalec M., Mehdi H., et al. Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias. Circulation 116 (2007) 2260-2268
16. Antzelevitch C., Pollevick G.D., Cordeiro J.M., et al. Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death. Circulation 115 (2007) 442-449
17. Martini B., Nava A., Thiene G., et al. Ventricular fibrillation without apparent heart disease: description of six cases. Am Heart J 118 (1989) 1203-1209
18. Antzelevitch C. Brugada syndrome. Pacing Clin Electrophysiol 29 (2006) 1130-1159
19. Ikeda T., Abe A., Yusu S., et al. The full stomach test as a novel diagnostic technique for identifying patients at risk of Brugada syndrome. J Cardiovasc Electrophysiol 17 (2006) 602-607
20. Brugada R., Brugada J., Antzelevitch C., et al. Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts. Circulation 101 (2000) 510-515
21. 3. Circulation 105 (2002) 73-78
22. Priori S.G., Napolitano C., Gasparini M., et al. Natural history of Brugada syndrome: insights for risk stratification and management. Circulation 105 (2002) 1342-1347
23. Fish J.M., and Antzelevitch C. Role of sodium and calcium channel block in unmasking the Brugada syndrome. Heart Rhythm 1 (2004) 210-217
24. Frustaci A., Priori S.G., Pieroni M., et al. Cardiac histological substrate in patients with clinical phenotype of Brugada syndrome. Circulation 112 (2005) 3680-3687
25. Yamada T., Watanabe I., Okumura Y., et al. Atrial electrophysiological abnormality in patients with Brugada syndrome assessed by P-wave signal-averaged ECG and programmed atrial stimulation. Circ J 70 (2006) 1574-1579
26. Yokokawa M., Noda T., Okamura H., et al. Comparison of long-term follow-up of electrocardiographic features in Brugada syndrome between the SCN5A-positive probands and the SCN5A-negative probands. Am J Cardiol 100 (2007) 649-655
27. Bigi M.A., Aslani A., and Shahrzad S. Clinical predictors of atrial fibrillation in Brugada syndrome. Europace 9 (2007) 947-950
28. Ogawa M., Zhou S., Tan A.Y., et al. Left stellate ganglion and vagal nerve activity and cardiac arrhythmias in ambulatory dogs with pacing-induced congestive heart failure. J Am Coll Cardiol 50 (2007) 335-343
29. Yan G.X., and Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation 100 (1999) 1660-1666
30. Nolasco J.B., and Dahlen R.W. A graphic method for the study of alternation in cardiac action potentials. J Appl Physiol 25 (1968) 191-196
31. Garfinkel A., Chen P.-S., Walter D.O., et al. Quasiperiodicity and chaos in cardiac fibrillation. J Clin Invest 99 (1997) 305-314
32. Riccio M.L., Koller M.L., and Gilmour R.F.J. Electrical restitution and spatiotemporal organization during ventricular fibrillation. Circ Res 84 (1999) 955-963
33. Nash M.P., Bradley C.P., Sutton P.M., et al. Whole heart action potential duration restitution properties in cardiac patients: a combined clinical and modelling study. Exp Physiol 91 (2006) 339-354
34. Pastore J.M., Laurita K.R., and Rosenbaum D.S. Importance of spatiotemporal heterogeneity of cellular restitution in mechanism of arrhythmogenic discordant alternans. Heart Rhythm 3 (2006) 711-719
35. Weiss J.N., Karma A., Shiferaw Y., Chen P.S., Garfinkel A., and Qu Z. From pulsus to pulseless: the saga of cardiac alternans. Circ Res 98 (2006) 1244-1253
36. Wu T.-J., Lin S.-F., Weiss J.N., Ting C.-T., and Chen P.-S. Two types of ventricular fibrillation in isolated rabbit hearts: importance of excitability and action potential duration restitution. Circulation 106 (2002) 1859-1866
37. Rossenbacker T., and Priori S.G. The Brugada syndrome. Curr Opin Cardiol 22 (2007) 163-170
38. Burashnikov A., and Antzelevitch C. Late-phase 3 EAD. A unique mechanism contributing to initiation of atrial fibrillation. Pacing Clin Electrophysiol 29 (2006) 290-295
39. Patterson E., Po S.S., Scherlag B.J., and Lazzara R. Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation. Heart Rhythm 2 (2005) 624-631
40. 2+ transient: an arrhythmia trigger within pulmonary veins. J Am Coll Cardiol 47 (2006) 1196-1206
41. Maury P., Couderc P., Delay M., Boveda S., and Brugada J. Electrical storm in Brugada syndrome successfully treated using isoprenaline. Europace 6 (2004) 130-133
42. Zipes D.P., Camm A.J., Borggrefe M., et al. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death). J Am Coll Cardiol 48 (2006) e247-e346
43. Nademanee K., Veerakul G., Mower M., et al. Defibrillator Versus beta-Blockers for Unexplained Death in Thailand (DEBUT): a randomized clinical trial. Circulation 107 (2003) 2221-2226
44. Belhassen B., Glick A., and Viskin S. Efficacy of quinidine in high-risk patients with Brugada syndrome. Circulation 110 (2004) 1731-1737
45. Mizusawa Y., Sakurada H., Nishizaki M., and Hiraoka M. Effects of low-dose quinidine on ventricular tachyarrhythmias in patients with Brugada syndrome: low-dose quinidine therapy as an adjunctive treatment. J Cardiovasc Pharmacol 47 (2006) 359-364
46. Ohgo T., Okamura H., Noda T., et al. Acute and chronic management in patients with Brugada syndrome associated with electrical storm of ventricular fibrillation. Heart Rhythm 4 (2007) 695-700