Diacylglycerol kinase ζ inhibits myocardial atrophy and restores cardiac dysfunction in streptozotocin-induced diabetes mellitus

Cardiovascular Diabetology

Volumn 7, Issue , 2008, Pages

  Bilim, Olga ^a   Takeishi, Yasuchika ^a   Kitahara, Tatsuro ^a   Arimoto, Takanori ^a   Niizeki, Takeshi ^a   Sasaki, Toshiki ^a   Goto, Kaoru ^a   Kubota, Isao ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL KINASE; DIACYLGLYCEROL KINASE ZETA; PROTEIN KINASE B; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; STREPTOZOCIN; UNCLASSIFIED DRUG; DIACYLGLYCEROL KINASE ZETA, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; BODY WEIGHT; CARDIOMYOPATHY; CELL SIZE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG TARGETING; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME REGULATION; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE SEPTUM; HEART WEIGHT; HISTOPATHOLOGY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; TISSUE SPECIFICITY; TRANSGENIC MOUSE; WESTERN BLOTTING; WILD TYPE; ANIMAL; DIABETIC ANGIOPATHY; ECHOGRAPHY; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; HEART; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HISTOLOGY; METABOLISM; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; ATROPHY; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC ANGIOPATHIES; DIACYLGLYCEROL KINASE; ECHOCARDIOGRAPHY; HEART; MICE; MICE, TRANSGENIC; MYOCARDIUM; ORGAN SIZE; STREPTOZOCIN; VENTRICULAR DYSFUNCTION, LEFT;

EID: 40749103728     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-7-2     Document Type: Article

References (42)

1. Kannel WB Hjortland M Castelli WP Role of diabetes in congestive heart failure: The Framingham study Am J Cardiol 1974, 34:29-34. 10.1016/ 0002-9149(74)90089-7 4835750
2. Arikawa E Ma RC Isshiki K Luptak I He Z Yasuda Y Maeno Y Patti ME Weir GC Harris RA Zammit VA Tian R King GL Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats Diabetes 2007, 56:1410-1420. 10.2337/db06-0655 17363743
3. Guo M Wu MH Korompai F Yuan SY Upregulation of PKC genes and isozymes in cardiovascular tissues during early stages of experimental diabetes Physiol Genomics 2003, 12:139-146. 12441406
4. Kang N Alexander G Park JK Maasch C Buchwalow I Luft FC Haller H Differential expression of protein kinase C isoforms in streptozotocin-induced diabetic rats Kidney Int 1999, 56:1737-1750. 10.1046/j.1523-1755.1999.00725.x 10571782
5. Topham MK Prescott SM Diacylglycerol kinases: Regulation and signaling roles Thromb Haemost 2002, 88:912-918. 12529738
6. Kanoh H Yamada K Sakane F Diacylglycerol kinases: Emerging downstream regulators in cell signaling systems J Biochem (Tokyo) 2002, 131:629-633.
7. Takeda M Kagaya Y Takahashi J Sugie T Ohta J Watanabe J Shirato K Kondo H Goto K Gene expression and in situ localization of diacylglycerol kinase isozymes in normal and infarcted rat hearts: Effects of captopril treatment Circ Res 2001, 89:265-272. 10.1161/hh1501.094185 11485977
8. Niizeki T Takeishi Y Arimoto T Takahashi H Shishido T Koyama Y Goto K Walsh RA Kubota I Cardiac-specific overexpression of diacylglycerol kinase zeta attenuates left ventricular remodeling and improves survival after myocardial infarction Am J Physiol Heart Circ Physiol 2007, 292:H1105-1112. 10.1152/ajpheart.00927.2006 17071729
9. Arimoto T Takeishi Y Takahashi H Shishido T Niizeki T Koyama Y Shiga R Nozaki N Nakajima O Nishimaru K Abe J Endoh M Walsh RA Goto K Kubota I Cardiac-specific overexpression of diacylglycerol kinase zeta prevents Gq protein-coupled receptor agonist-induced cardiac hypertrophy in transgenic mice Circulation 2006, 113:60-66. 10.1161/ CIRCULATIONAHA.105.560771 16380548
10. Harada M Takeishi Y Arimoto T Niizeki T Kitahara T Goto K Walsh RA Kubota I Diacylglycerol kinase zeta attenuates pressure overload-induced cardiac hypertrophy Circ J 2007, 71:276-282. 10.1253/circj.71.276 17251681
11. Nozaki N Shishido T Takeishi Y Kubota I Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice Circulation 2004, 110:2869-2874. 10.1161/01.CIR.0000146889.46519.27 15505089
12. Shishido T Nozaki N Yamaguchi S Shibata Y Nitobe J Miyamoto T Takahashi H Arimoto T Maeda K Yamakawa M Takeuchi O Akira S Takeishi Y Kubota I Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction Circulation 2003, 108:2905-2910. 10.1161/ 01.CIR.0000101921.93016.1C 14656915
13. Harada K Sugaya T Murakami K Yazaki Y Komuro I Angiotensin II type 1A receptor knockout mice display less left ventricular remodeling and improved survival after myocardial infarction Circulation 1999, 100:2093-209. 10562266
14. Takeishi Y Abe J Lee JD Kawakatsu H Walsh RA Berk BC Differential regulation of p90 ribosomal S6 kinase and big mitogen-activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts Circ Res 1999, 85:1164-1172. 10590243
15. Takeishi Y Huang Q Abe J Glassman M Che W Lee JD Kawakatsu H Lawrence EG Hoit BD Berk BC Walsh RA Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: Comparison with acute mechanical stretch J Mol Cell Cardiol 2001, 33:1637-1648. 10.1006/jmcc.2001.1427 11549343
16. Takahashi H Takeishi Y Miyamoto T Shishido T Arimoto T Konta T Miyashita T Ito M Kubota I Protein kinase C and extracellular signal regulated kinase are involved in cardiac hypertrophy of rats with progressive renal injury Eur J Clin Invest 2004, 34:85-93. 10.1111/ j.1365-2362.2004.01304.x 14764070
17. Cai F Helke CJ Abnormal PI3 kinase/Akt signal pathway in vagal afferent neurons and vagus nerve of streptozotocin-diabetic rats Brain Res Mol Brain Res 2003, 110:234-244. 10.1016/S0169-328X(02)00652-6 12591159
18. Shiojima I Yefremashvili M Luo Z Kureishi Y Takahashi A Tao J Rosenzweig A Kahn CR Abel ED Walsh K Akt signaling mediates postnatal heart growth in response to insulin and nutritional status J Biol Chem 2002, 277:37670-37677. 10.1074/jbc.M204572200 12163490
19. Kobayashi T Matsumoto T Kamata K The PI3-K/Akt pathway: Roles related to alterations in vasomotor responses in diabetic models J Smooth Muscle Res 2005, 41:283-302. 10.1540/jsmr.41.283 16557003
20. O'Neill BT Abel ED Akt1 in the cardiovascular system: Friend or foe? J Clin Invest 2005, 115:2059-2064. 1180557 16075047 10.1172/JCI25900
21. Huisamen B Protein kinase B in the diabetic heart Mol Cell Biochem 2003, 249:31-38. 10.1023/A:1024749614222 12956395
22. Inoguchi T Battan R Handler E Sportsman JR Heath W King GL Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: Differential reversibility to glycemic control by islet cell transplantation Proc Natl Acad Sci USA 1992, 89:11059-11063. 50483 1438315 10.1073/pnas.89.22.11059
23. Davidoff AJ Davidson MB Carmody MW Davis ME Ren J Diabetic cardiomyocyte dysfunction and myocyte insulin resistance: Role of glucose-induced PKC activity Mol Cell Biochem 2004, 262:155-163. 10.1023/ B:MCBI.0000038231.68078.4b 15532720
24. Way KJ Isshiki K Suzuma K Yokota T Zvagelsky D Schoen FJ Sandusky GE Pechous PA Vlahos CJ Wakasaki H King GL Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes Diabetes 2002, 51:2709-2718. 10.2337/diabetes.51.9.2709 12196463
25. Aiello LP Davis MD Girach A Kles KA Milton RC Sheetz MJ Vignati L Zhi XE Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy Ophthalmology 2006, 113:2221-2230. 10.1016/ j.ophtha.2006.07.032 16989901
26. Takahashi H Takeishi Y Seidler T Arimoto T Akiyama H Hozumi Y Koyama Y Shishido T Tsunoda Y Niizeki T Nozaki N Abe J Hasenfuss G Goto K Kubota I Adenovirus-mediated overexpression of diacylglycerol kinase-zeta inhibits endothelin-1-induced cardiomyocyte hypertrophy Circulation 2005, 111:1510-1516. 10.1161/01.CIR.0000159339.00703.22 15781737
27. Hayat SA Patel B Khattar RS Malik RA Diabetic cardiomyopathy: mechanisms, diagnosis and treatment Clin Sci (Lond) 2004, 107:539-557. 15341511
28. Shindler DM Kostis JB Yusuf S Quinones MA Pitt B Stewart D Pinkett T Ghali JK Wilson AC Diabetes mellitus, a predictor of morbidity and mortality in the Studies of Left Ventricular Dysfunction (SOLVD) Trials and Registry Am J Cardiol 1996, 77:1017-1020. 10.1016/ S0002-9149(97)89163-1 8644628
29. Poornima IG Parikh P Shannon RP Diabetic cardiomyopathy: The search for a unifying hypothesis Circ Res 2006, 98:596-605. 10.1161/ 01.RES.0000207406.94146.c2 16543510
30. Nemoto O Kawaguchi M Yaoita H Miyake K Maehara K Maruyama Y Left ventricular dysfunction and remodeling in streptozotocin-induced diabetic rats Circ J 2006, 70:327-334. 10.1253/circj.70.327 16501301
31. Depre C Young ME Ying J Ahuja HS Han Q Garza N Davies PJ Taegtmeyer H Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction J Mol Cell Cardiol 2000, 32:985-996. 10.1006/jmcc.2000.1139 10888252
32. Kawaguchi M Asakura T Saito F Nemoto O Maehara K Miyake K Sugai N Maruyama Y Changes in diameter size and F-actin expression in the myocytes of patients with diabetes and streptozotocin-induced diabetes model rats J Cardiol 1999, 34:333-339. 10642930
33. Rodrigues B Cam MC McNeill JH Metabolic disturbances in diabetic cardiomyopathy Mol Cell Biochem 1998, 180:53-57. 10.1023/A:1006882805197 9546630
34. Naruse K Rask-Madsen C Takahara N Ha SW Suzuma K Way KJ Jacobs JR Clermont AC Ueki K Ohshiro Y Zhang J Goldfine AB King GL Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance Diabetes 2006, 55:691-698. 10.2337/diabetes.55.03.06.db05-0771 16505232
35. Li L Sampat K Hu N Zakari J Yuspa SH Protein kinase C regatively regulates Akt activity and modifies UVC-induced apoptosis in mouse keratinocytes J Biol Chem 2006, 281:3237-3243. 10.1074/jbc.M512167200 16338928
36. Wen HC Huang WC Ali A Woodgett JR Lin WW Negative regulation of phosphatidylinositol 3-kinase and Akt signaling pathway by PKC Cell Signal 2002, 15:37-45. 10.1016/S0898-6568(02)00047-5
37. Goto K Kondo H A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus Proc Natl Acad Sci USA 1996, 93:11196-11201. 38307 8855332 10.1073/pnas.93.20.11196
38. Goto K Hozumi Y Kondo H Diacylglycerol, phosphatidic acid, and the converting enzyme, diacylglycerol kinase, in the nucleus Biochim Biophys Acta 2006, 1761:535-541. 16731035
39. Takeishi Y Goto K Kubota I Role of diacylglycerol kinase in cellular regulatory processes Pharmacol Ther 2007, 115:352-359. 10.1016/ j.pharmthera.2007.04.010 17659347
40. Jones DR Sanjuan MA Merida I Type Ialpha phosphatidylinositol 4-phosphate 5-kinase is a putative target for increased intracellular phosphatidic acid FEBS Lett 2000, 476:160-165. 10.1016/ S0014-5793(00)01702-6 10913605
41. Czech MP PIP2 and PIP3: Complex roles at the cell surface Cell 2000, 100:603-606. 10.1016/S0092-8674(00)80696-0 10761925
42. Condorelli G Drusco A Stassi G Bellacosa A Roncarati R Iaccarino G Russo MA Gu Y Dalton N Chung C Latronico MV Napoli C Sadoshima J Croce CM Ross J Jr Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice Proc Natl Acad Sci USA 2002, 99:12333-12338. 129445 12237475 10.1073/pnas.172376399