Impact of chicken thrombopoietin and its receptor c-Mpl on hematopoietic cell development

Experimental Hematology

Volumn 36, Issue 4, 2008, Pages 495-505

  Bartunek, Petr ^a   Karafiat, Vit ^a   Bartunkova, Jana ^a   Pajer, Petr ^a   Dvorakova, Marta ^a   Kralova, Jarmila ^a   Zenke, Martin ^b   Dvorak, Michal ^a  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; PROTEIN C MPL; RECEPTOR PROTEIN; RNA; THROMBOPOIETIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BONE MARROW; C MPL GENE; CELL FATE; CELL PROLIFERATION; CHICK EMBRYO; CHICKEN; CONTROLLED STUDY; EMBRYO; ERYTHROBLASTOSIS; GENE; GENE OVEREXPRESSION; GROWTH STIMULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LIVER; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SPLEEN; TISSUE DISTRIBUTION; TPO GENE;

ANIMALIA;

EID: 40649108513     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2007.12.001     Document Type: Article

References (66)

1. S.H. Orkin L.I. Zon Hematopoiesis and stem cells: plasticity versus developmental heterogeneity Nat Immunol 3 2002 323 328
2. K. Kaushansky Lineage-specific hematopoietic growth factors N Engl J Med 354 2006 2034 2045
3. M. Loose R. Patient Global genetic regulatory networks controlling hematopoietic cell fates Curr Opin Hematol 13 2006 229 236
4. K. Akashi D. Traver T. Miyamoto I.L. Weissman A clonogenic common myeloid progenitor that gives rise to all myeloid lineages Nature 404 2000 193 197
5. J. Adolfsson R. Mansson N. Buza-Vidas Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment Cell 121 2005 295 306
6. D. Metcalf The molecular control of hematopoiesis: progress and problems with gene manipulation Stem Cells 16 Suppl 2 1998 1 9
7. S.H. Orkin Diversification of haematopoietic stem cells to specific lineages Nat Rev Genet 1 2000 57 64
8. T. Graf Differentiation plasticity of hematopoietic cells Blood 99 2002 3089 3101
9. E.M. Cramer Megakaryocyte structure and function Curr Opin Hematol 6 1999 354 361
10. H. Schulze R.A. Shivdasani Mechanisms of thrombopoiesis J Thromb Haemost 3 2005 1717 1724
11. L. Pang M.J. Weiss M. Poncz Megakaryocyte biology and related disorders J Clin Invest 115 2005 3332 3338
12. S.R. Patel J.H. Hartwig J.E. Italiano Jr. The biogenesis of platelets from megakaryocyte proplatelets J Clin Invest 115 2005 3348 3354
13. K. Kaushansky Thrombopoietin: the primary regulator of platelet production Blood 86 1995 419 431
14. T. Kato A. Matsumoto K. Ogami T. Tahara H. Morita H. Miyazaki Native thrombopoietin: structure and function Stem Cells 16 1998 322 328
15. T.D. Bartley J. Bogenberger P. Hunt Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl Cell 77 1994 1117 1124
16. F.J. de Sauvage P.E. Hass S.D. Spencer Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand Nature 369 1994 533 538
17. S. Lok K. Kaushansky R.D. Holly Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo Nature 369 1994 565 568
18. F. Wendling E. Maraskovsky N. Debili cMpl ligand is a humoral regulator of megakaryocytopoiesis Nature 369 1994 571 574
19. I. Vigon J.P. Mornon L. Cocault Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily Proc Natl Acad Sci U S A 89 1992 5640 5644
20. G.P. Solar W.G. Kerr F.C. Zeigler Role of c-mpl in early hematopoiesis Blood 92 1998 4 10
21. E. Sitnicka N. Lin G.V. Priestley The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells Blood 87 1996 4998 5005
22. J.L. Abkowitz J. Chen Studies of c-Mpl function distinguish the replication of hematopoietic stem cells from the expansion of differentiating clones Blood 109 2007 5186 5190
23. W.S. Alexander Thrombopoietin and the c-Mpl receptor: insights from gene targeting Int J Biochem Cell Biol 31 1999 1027 1035
24. M. Murone D.A. Carpenter F.J. de Sauvage Hematopoietic deficiencies in c-mpl and TPO knockout mice Stem Cells 16 1998 1 6
25. S. Bunting R. Widmer T. Lipari Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin Blood 90 1997 3423 3429
26. S.T. Avecilla K. Hattori B. Heissig Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis Nat Med 10 2004 64 71
27. W.S. Alexander A.W. Roberts N.A. Nicola R. Li D. Metcalf Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl Blood 87 1996 2162 2170
28. S. Kimura A.W. Roberts D. Metcalf W.S. Alexander Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin Proc Natl Acad Sci U S A 95 1998 1195 1200
29. K. Kaushansky The molecular mechanisms that control thrombopoiesis J Clin Invest 115 2005 3339 3347
30. I. Hadji-Azimi V. Coosemans C. Canicatti Atlas of adult Xenopus laevis laevis hematology Dev Comp Immunol 11 1987 807 874
31. E. Maurer-Spurej Circulating serotonin in vertebrates Cell Mol Life Sci 62 2005 1881 1889
32. A.S. Lacoste-Eleaume C. Bleux P. Quere F. Coudert C. Corbel C. Kanellopoulos-Langevin Biochemical and functional characterization of an avian homolog of the integrin GPIIb-IIIa present on chicken thrombocytes Exp Cell Res 213 1994 198 209
33. R.A. DaMatta L. Manhaes E. Lassounskaia W. de Souza Chicken thrombocytes in culture: lymphocyte-conditioned medium delays apoptosis Tissue Cell 31 1999 255 263
34. P. Jagadeeswaran J.P. Sheehan F.E. Craig D. Troyer Identification and characterization of zebrafish thrombocytes Br J Haematol 107 1999 731 738
35. G. Soslau P.J. Prest R. Class R. George F. Paladino G. Violetta Comparison of sea turtle thrombocyte aggregation to human platelet aggregation in whole blood Comp Biochem Physiol B Biochem Mol Biol 142 2005 353 360
36. T. Graf K. McNagny G. Brady J. Frampton Chicken “erythroid” cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent Cell 70 1992 201 213
37. M. Garcia J. Samarut v-jun cooperates with v-erbB to transform the thrombocytic/megakaryocytic lineage Proc Natl Acad Sci U S A 90 1993 8837 8841
38. J. Frampton K. McNagny M. Sieweke A. Philip G. Smith T. Graf v-Myb DNA binding is required to block thrombocytic differentiation of Myb-Ets-transformed multipotent haematopoietic progenitors EMBO J 14 1995 2866 2875
39. H. Kulessa J. Frampton T. Graf GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts Genes Dev 9 1995 1250 1262
40. P. Bartunek V. Karafiat M. Dvorakova The Myb leucine zipper is essential for leukemogenicity of the v-Myb protein Oncogene 15 1997 2939 2949
41. K.M. McNagny F. Lim S. Grieser T. Graf Cell surface proteins of chicken hematopoietic progenitors, thrombocytes and eosinophils detected by novel monoclonal antibodies Leukemia 6 1992 975 984
42. H. Beug P. Steinlein P. Bartunek M.J. Hayman Avian hematopoietic cell culture: in vitro model systems to study oncogenic transformation of hematopoietic cells Methods Enzymol 254 1995 41 76
43. P. Bartunek L. Pichlikova G. Stengl Avian stem cell factor (SCF): production and characterization of the recombinant His-tagged SCF of chicken and its neutralizing antibody Cytokine 8 1996 14 20
44. P.E. Boardman J. Sanz-Ezquerro I.M. Overton A comprehensive collection of chicken cDNAs Curr Biol 12 2002 1965 1969
45. P. Steinlein E. Deiner A. Leutz H. Beug Recombinant murine erythropoietin receptor expressed in avian erythroid progenitors mediates terminal erythroid differentiation in vitro Growth Factors 10 1994 1 16
46. K. Vranovsky P. Bartunek V. Cermakova J. Forstova M. Dvorak J. Doskocil Production of v-Myb and c-Myb in insect cells infected with recombinant baculoviruses Gene 117 1992 233 235
47. P. Bartunek P. Pajer V. Karafiat G. Blendinger M. Dvorak M. Zenke bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors Oncogene 21 2002 400 410
48. E. Birney D. Andrews M. Caccamo Ensembl 2006 Nucleic Acids Res 34 2006 D556 D561
49. D. Foster S. Lok Biological roles for the second domain of thrombopoietin Stem Cells 14 suppl 1 1996 102 107
50. H.M. Linden K. Kaushansky The glycan domain of thrombopoietin enhances its secretion Biochemistry 39 2000 3044 3051
51. V. Mignotte I. Vigon E. Boucher de Crevecoeur P.H. Romeo V. Lemarchandel S. Chretien Structure and transcription of the human c-mpl gene (MPL) Genomics 20 1994 5 12
52. W.S. Alexander A.R. Dunn Structure and transcription of the genomic locus encoding murine c-Mpl, a receptor for thrombopoietin Oncogene 10 1995 795 803
53. H.F. Lin D. Traver H. Zhu Analysis of thrombocyte development in CD41-GFP transgenic zebrafish Blood 106 2005 3803 3810
54. W.S. Alexander A.B. Maurer U. Novak M. Harrison-Smith Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation EMBO J 15 1996 6531 6540
55. H. Park S.S. Park E.H. Jin Identification of functionally important residues of human thrombopoietin J Biol Chem 273 1998 256 261
56. L. Cocault D. Bouscary C. Le Bousse Kerdiles Ectopic expression of murine TPO receptor (c-mpl) in mice is pathogenic and induces erythroblastic proliferation Blood 88 1996 1656 1665
57. X.Q. Yan D.L. Lacey C. Saris Ectopic overexpression of c-mpl by retroviral-mediated gene transfer suppressed megakaryopoiesis but enhanced erythropoiesis in mice Exp Hematol 27 1999 1409 1417
58. W. Zhou C.F. Toombs T. Zou J. Guo M.O. Robinson Transgenic mice overexpressing human c-mpl ligand exhibit chronic thrombocytosis and display enhanced recovery from 5-fluorouracil or antiplatelet serum treatment Blood 89 1997 1551 1559
59. R.G. Andrews A. Winkler D. Myerson Recombinant human ligand for MPL, megakaryocyte growth and development factor (MGDF), stimulates thrombopoiesis in vivo in normal and myelosuppressed baboons Stem Cells 14 1996 661 677
60. K. Kabaya H. Akahori K. Shibuya In vivo effects of pegylated recombinant human megakaryocyte growth and development factor on hematopoiesis in normal mice Stem Cells 14 1996 651 660
61. W.S. Alexander Thrombopoietin Growth Factors 17 1999 13 24
62. D. Metcalf L. Di Rago S. Mifsud Synergistic and inhibitory interactions in the in vitro control of murine megakaryocyte colony formation Stem Cells 20 2002 552 560
63. H. Dolznig P. Bartunek K. Nasmyth E.W. Mullner H. Beug Terminal differentiation of normal chicken erythroid progenitors: shortening of G1 correlates with loss of D-cyclin/cdk4 expression and altered cell size control Cell Growth Differ 6 1995 1341 1352
64. A.B. Cantor S.H. Orkin Transcriptional regulation of erythropoiesis: an affair involving multiple partners Oncogene 21 2002 3368 3376
65. K. Kirito K. Kaushansky Transcriptional regulation of megakaryopoiesis: thrombopoietin signaling and nuclear factors Curr Opin Hematol 13 2006 151 156
66. R.A. Shivdasani Molecular and transcriptional regulation of megakaryocyte differentiation Stem Cells 19 2001 397 407