Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction

Journal of Molecular and Cellular Cardiology

Volumn 44, Issue 3, 2008, Pages 486-495

  Perin, Emerson C ^a   Silva, Guilherme V ^a   Assad, Joao A R ^a   Vela, Deborah ^a,b   Buja, L Maximilian ^a,b   Sousa, Andre L S ^a   Litovsky, Silvio ^a   Lin, Jing ^a   Vaughn, William K ^a   Coulter, Stephanie ^a   Fernandes, Marlos R ^a,b   Willerson, James T ^a,b  

^a ST LUKE S EPISCOPAL HOSPITAL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Acute myocardial infarction; Intracoronary delivery; Mesenchymal stem cell; Stem cell injection; Stem cell therapy; Transendocardial delivery

Indexed keywords

ACUTE HEART INFARCTION; ANGIOCARDIOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DENSITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOG; ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE EJECTION FRACTION; HEMATOPOIETIC STEM CELL; HISTOPATHOLOGY; INTERMETHOD COMPARISON; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; VASCULAR FIBROSIS;

ANIMALS; CORONARY VESSELS; DOGS; ENDOCARDIUM; FOLLOW-UP STUDIES; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MYOCARDIAL INFARCTION; TRANSPLANTATION, HOMOLOGOUS;

EID: 40649104145     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2007.09.012     Document Type: Article

References (34)

1. Assmus B., Schachinger V., Teupe C., Britten M., Lehmann R., Dobert N., et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 106 (2002) 3009-3017
2. Britten M.B., Abolmaali N.D., Assmus B., Lehmann R., Honold J., Schmitt J., et al. Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation 108 (2003) 2212-2218
3. Chen S.L., Fang W.W., Ye F., Liu Y.H., Qian J., Shan S.J., et al. Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. Am J Cardiol 94 (2004) 92-95
4. Janssens S., Dubois C., Bogaert J., Theunissen K., Deroose C., Desmet W., et al. Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet 367 (2006) 113-121
5. Strauer B.E., Brehm M., Zeus T., Kostering M., Hernandez A., Sorg R.V., et al. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 106 (2002) 1913-1918
6. Wollert K.C., Meyer G.P., Lotz J., Ringes-Lichtenberg S., Lippolt P., Breidenbach C., et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 364 (2004) 141-148
7. Schachinger V., Erbs S., Elsasser A., Haberbosch W., Hambrecht R., Holschermann H., et al. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 355 (2006) 1210-1221
8. Vulliet P.R., Greeley M., Halloran S.M., MacDonald K.A., and Kittleson M.D. Intra-coronary arterial injection of mesenchymal stromal cells and microinfarction in dogs. Lancet 363 (2004) 783-784
9. Chazaud B., Hittinger L., Sonnet C., Champagne S., Le Corvoisier P., Benhaiem-Sigaux N., et al. Endoventricular porcine autologous myoblast transplantation can be successfully achieved with minor mechanical cell damage. Cardiovasc Res 58 (2003) 444-450
10. Forrester J.S., Price M.J., and Makkar R.R. Stem cell repair of infarcted myocardium: an overview for clinicians. Circulation 108 (2003) 1139-1145
11. Orlic D., Kajstura J., Chimenti S., Jakoniuk I., Anderson S.M., Li B., et al. Bone marrow cells regenerate infarcted myocardium. Nature 410 (2001) 701-705
12. Perin E.C., Dohmann H.F., Borojevic R., Silva S.A., Sousa A.L., Silva G.V., et al. Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy. Circulation 110 (2004) II213-II218
13. Kornowski R., and Fuchs S. Catheter-based transendocardial gene delivery for therapeutic myocardial angiogenesis. Int J Cardiovasc Intervent 3 (2000) 67-70
14. Perin E.C., Silva G.V., and Sarmento-Leite R. Assessing myocardial viability and infarct transmurality with left ventricular electromechanical mapping in patients with stable coronary artery disease: validation by delayed-enhancement magnetic resonance imaging. Circulation 106 (2002) 957-961
15. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., et al. Multilineage potential of adult human mesenchymal stem cells. Science 284 (1999) 143-147
16. Vale P.R., Losordo D.W., Milliken C.E., Maysky M., Esakof D.D., Symes J.F., et al. Left ventricular electromechanical mapping to assess efficacy of phVEGF(165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia. Circulation 102 (2000) 965-974
17. Kawamoto A., Tkebuchava T., Yamaguchi J., Nishimura H., Yoon Y.S., Milliken C., et al. Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemia. Circulation 107 (2003) 461-468
18. Morillo C.A., Klein G.J., Jones D.L., and Guiraudon C.M. Chronic rapid atrial pacing. Structural, functional, and electrophysiological characteristics of a new model of sustained atrial fibrillation. Circulation 91 (1995) 1588-1595
19. Sahn D.J., DeMaria A., Kisslo J., and Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 58 (1978) 1072-1083
20. Bush L.R., Buja L.M., Samowitz W., Rude R.E., Wathen M., Tilton G.D., et al. Recovery of left ventricular segmental function after long-term reperfusion following temporary coronary occlusion in conscious dogs. Comparison of 2- and 4-hour occlusions. Circ Res 53 (1983) 248-263
21. Shake J.G., Gruber P.J., Baumgartner W.A., Senechal G., Meyers J., Redmond J.M., et al. Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects. Ann Thorac Surg 73 (2002) 1919-1925 [discussion 1926]
22. Walter D.H., Haendeler J., Reinhold J., Rochwalsky U., Seeger F., Honold J., et al. Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease. Circ Res 97 (2005) 1142-1151
23. Pittenger M.F., and Martin B.J. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 95 (2004) 9-20
24. Dai W., Hale S.L., Martin B.J., Kuang J.Q., Dow J.S., Wold L.E., et al. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation 112 (2005) 214-223
25. Müller-Ehmsen J., Krausgrill B., Burst V., Schenk K., Neisen U.C., Fries J.W., et al. Effective engraftment but poor mid-term persistence of mononuclear and mesenchymal bone marrow cells in acute and chronic rat myocardial infarction. J Mol Cell Cardiol 41 (2006) 876-884
26. Hu X., Wang J., Chen J., Luo R., He A., Xie X., et al. Optimal temporal delivery of bone marrow mesenchymal stem cells in rats with myocardial infarction. Eur J Cardiothorac Surg 31 (2007) 438-443
27. Amado L.C., Saliaris A.P., Schuleri K.H., St John M., Xie J.S., Cattaneo S., et al. Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction. Proc Natl Acad Sci U S A 102 (2005) 11474-11479
28. Hou D., Youssef E.A., Brinton T.J., Zhang P., Rogers P., Price ET., et al. Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials. Circulation 112 (2005) I150-I156
29. Freyman T., Polin G., Osman H., Crary J., Lu M., Cheng L., et al. A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. Eur Heart J 27 (2006) 1114-1122
30. Agbulut O., Vandervelde S., Al Attar N., Larghero J., Ghostine S., Leobon B., et al. Comparison of human skeletal myoblasts and bone marrow-derived CD133+ progenitors for the repair of infarcted myocardium. J Am Coll Cardiol 44 (2004) 458-463
31. Kinnaird T., Stabile E., Burnett M.S., Shou M., Lee C.W., Barr S., et al. Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation 109 (2004) 1543-1549
32. Kelly R.V., Cohen M.G., Runge M.S., and Stouffer G.A. The no-reflow phenomenon in coronary arteries. J Thromb Haemost 2 (2004) 1903-1907
33. Willerson J.T., Watson J.T., Hutton I., Templeton G.H., and Fixler D.E. Reduced myocardial reflow and increased coronary vascular resistance following prolonged myocardial ischemia in the dog. Circ Res 36 (1975) 771-781
34. Yoon Y.S., Park J.S., Tkebuchava T., Luedeman C., and Losordo D.W. Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarction. Circulation 109 (2004) 3154-3157