Catheter-based transendocardial gene delivery for therapeutic myocardial angiogenesis

International Journal of Cardiovascular Interventions

Volumn 3, Issue 2, 2000, Pages 67-70

  Kornowski, R ^a   Fuchs, S ^a  

^a WASHINGTON HOSPITAL CENTER   (United States)

Author keywords

Angiogenesis; Gene therapy; Myocardium

Indexed keywords

ANGIOGENIC FACTOR; FIBROBLAST GROWTH FACTOR;

ANGIOGENESIS; CATHETERIZATION; ENDOCARDIAL DISEASE; GENE TARGETING; HEMODYNAMICS; INTRACORONARY INFUSION; PRIORITY JOURNAL; REVIEW; TRANSGENE; TREATMENT INDICATION;

EID: 0033781262     PISSN: 14628848     EISSN: None     Source Type: Journal    
DOI: 10.1080/14628840050516145     Document Type: Review

References (10)

1. Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for VEGF-12, improves myocardial perfusion and function in the ischemic porcine heart
2. Induction of neoangiogenesis in ischemic myocardium by human growth factors. First clinical results of a new treatment of coronary heart disease
3. Gene therapy for myocardial angiogenesis: Initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia
4. Angiogenesis gene therapy: Phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease
5. Percutaneous transluminal gene transfer into canine myocardium in vivo by replication-defective adenovirus
6. Percutaneous endocardial gene therapy: In vivo gene transfer and expression
7. Catheter-based myocardial gene-transfer utilizing nonfluoroscopic electromechanical left ventricular mapping
8. Successful gene transfer in a porcine ischemia model using the Biosense guided transendocardial injection catheter
9. Evaluation of the acute and chronic safety of the biosense injection catheter system in porcine hearts
10. Electromagnetic-guidance for catheter-based trans-endocardial injection: A platform for myocardial angiogenesis therapy: Results in normal and ischemic porcine model