Artemin activates axonal growth via SFK and ERK-dependent signalling pathways in mature dorsal root ganglia neurons

Cell Biochemistry and Function

Volumn 26, Issue 2, 2008, Pages 210-220

  Doc, Gyun Jeong ^a   Wyun, Kon Park ^a   Park, Seyeon ^b  

^a Yonsei University College of Medicine   (South Korea)

^b Dongduk Women's University   (South Korea)

Author keywords

Artemin; Axonal growth; ERK; SH3 binding partner; Src family kinase

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATASE; ARTEMIN; HEMATOPOIETIC CELL KINASE; MITOGEN ACTIVATED PROTEIN KINASE; NCK PROTEIN; PROTEIN TYROSINE KINASE; ZINC FINGER PROTEIN;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MICROTUBULE; NERVE CELL; NERVE FIBER GROWTH; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RAT; SPINAL GANGLION;

ACTINS; ANIMALS; AXONS; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GANGLIA, SPINAL; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE TISSUE PROTEINS; NEURONS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; SRC-FAMILY KINASES;

EID: 40649103883     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1436     Document Type: Article

References (56)

1. Brown MT, Cooper JA. Regulation substrates and functions of Src. Biochim Biophys Acta 1996; 1287: 121-149.
2. Bolen JB. Nonreceptor tyrosine protein kinases. Oncogene 1993; 8: 2025-2031.
3. Sichert F, Kuriyan J. Structures of Src-family tyrosine kinases. Curr Opin Struct Biol 1997; 7: 777-785.
4. France MC, Fincham VJ, Carragher NO, Wyke JA. V-Src's hold over actin and cell adhesions. Nat Rev Mol Cell Biol 2001; 3: 233-245.
5. Bjorge JD, Jakymiw A, Fujita DJ. Selected glimpses into the activation and function of Src kinase. Oncogene 2000; 19: 5620-5635.
6. Thomas SM, Brugge JS. Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 1997; 13: 513-609.
7. Scott MP, Zappacosta F, Kim EY, Annan RS, Miller WT. Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and EL MO1. J Biol Chem 2002; 277: 28238-28246.
8. Ralston R, Bishop JM. The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor. Proc Natl Acad Sci U S A 1985; 82: 7845-7849.
9. Clark EA, Brugge JS. Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets. Mol Cell Biol 1993; 13: 1863-1871.
10. Wong S, Reynolds AB, Papkoff J. Platelet activation leads to increased c-src kinase activity and association of c-src with an 85-kDa tyrosine phosphoprotein. Oncogene 1992; 7: 2407-2415.
11. Chen YH, Pouyssegur J, Courtneidge SA, Van Obberghen-Schilling E. Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts. J Biol Chem 1994; 269: 27372-27377.
12. Simonson MS, Herman WH. Protein kinase C and protein tyrosine kinase activity contribute to mitogenic signaling by endothelin-1. Cross-talk between G protein- coupled receptors and pp60c-src. J Biol Chem 1993; 268: 9347-9357.
13. Ptasznik A, Traynor-Kaplan A, Bokoch GM. G Protein- coupled chemoattractant receptors regulate Lyn tyrosine kinase Src adapter protein signaling complexes. J Biol Chem 1995; 270: 19969-19973.
14. Devary Y, Gottlieb RA, Smeal T, Karin M. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 1992; 71: 1081-1091.
15. Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS, Sukhatme VP. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 1995; 375: 577-581.
16. Rusanescu G, Qi H, Thomas SM, Brugge JS, Halegoua S. Calcium influx induces neurite growth through a Src-Ras signaling cassette. Neuron 1995; 15: 1415-1425.
17. Andres R, Forgie A, Wyatt S, Chen Q, de Sauvage FJ, Davies AM. Multiple effects of artemin on sympathetic neurone generation, survival and growth. Development 2001; 128: 3685-3695.
18. Yan H, Newgreen DF, Young HM. Developmental changes in neurite outgrowth responses of dorsal root and sympathetic ganglia to GDNF, neurturin, and artemin. Dev Dyn 2003; 227: 395-401.
19. Baudet C, Mikaels A, Westphal H, Johansen J, Johansen TE, Ernfors P. Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development 2000; 127: 4335-4344.
20. Arighi E, Borrello MG, Sariola H. RET tyrosine kinase signaling in development and cancer. Cytokine Growth Factor Rev 2005; 16: 441-467.
21. Park S, Hong Y. Transcriptional regulation of artemin is related to neurite outgrowth and actin polymerization in mature DRG neurons. Neuro Lett 2006; 404: 61-66.
22. Birge RB, Knudsen BS, Besser D, Hanafusa H. SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction. Genes Cells 1996; 1: 595-613.
23. Mayer BJ, Baltimore D. Signaling through SH2 and SH3 domains. Trends Cell Biol 1993; 3: 8-13.
24. Miyamoto Y, Yamauchi J, Mizuno N, Itoh H. The adaptor protein Nck1 mediates endothelin A receptor-regulated cell migration through the Cdc42-dependent c-Jun N-terminal kinase pathway. J Biol Chem 2004; 279: 34336-34342.
25. Piccardoni P, Sideri R, Manarini S, et al. Platelet/polymorpho- nuclear leukocyte adhesion: a new role for SRC kinases in Mac-1 adhesive function triggered by P-selectin. Blood 2001; 98: 108-116.
26. Nair KS, Zingde SM. Adhesion of neutrophils to fibronectin: role of the cd66 antigens. Cell Immunol 2001; 208: 96-106.
27. Kumar P, Hosaka S, Koch AESoluble. E-selectin induces monocyte Chemotaxis through Src family tyrosine kinases. J Biol Chem 2001; 276: 21039-21045.
28. Baloh RH, Tansy MG, Lampe PA, et al. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRα3-RET receptor complex. Neuron 1998; 21: 1291-1302.
29. Wang CY, Tang F, He XP, et al. Regualation of neuromuscular synapse development by glial cell line-derived neurotrophic factor and neurturin. J Biol Chem 2002; 277: 10614-10625.
30. Dent EW, Barnes AM, Tang F, Kalil K. Netrin-1 and Semaphorin 3A promote or inhibit cortical axon branching, respectively, by reorganization of the cytoskeleton. J Neurosci 2004; 24: 3002-3012.
31. Enomoto H, Crawford PA, Gorodinsky A, Heuckeroth RO, Johnson EM, Jr, Milbrandt J. RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons. Development 2001; 128: 3963-3974.
32. Paveliev M, Airksinen MS, Saarma M. GDNF family ligands activate multiple events during axonal growth in mature sensory neurons. Mol Cell Neurosci 2004; 25: 453-459.
33. Poteryaev D, Titievsky A, Sun YF, et al. GDNF triggers a novel ret-independent Src kinase family-coupled signaling via a GPI-linked GDNF receptor alphal. FEBS Lett 1999; 463: 63-66.
34. Blake RA, Broome MA, Liu X, et al. SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol Cell Biol 2000; 20: 9018-9027.
35. Mueller BK. Growth cone guidance: first steps towards a deeper understanding. Anu Rev Neurosci 1999; 22: 351-388.
36. McCarty JH. The Nek SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events. Bioessays 1998; 20: 913-921.
37. Ducraya A, Krebsa SH, Schallera B, Seilera RW, Meyerb M, Widmera HR. GDNF family ligands display distinct action profiles on cultured GABAergic and serotonergic neurons of rat ventral mesencephalon. Brain Res 2006; 1069: 104-112.
38. Zihlmanna KB, Ducraya AD, Schallera B, et al. The GDNF family members neurturin, artemin and persephin promote the morphological differentiation of cultured ventral mesencephalic dopaminergic neurons. Brain Res Bull 2005; 68: 42-53.
39. Da Silva JS, Dotti CG. Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis. Nat Rev Neurosci 2002; 3: 694-704.
40. Rauvaia H, Peng HB. HB-GAM (heparin-binding growth-associated molecule) and heparin-type glycans in the development and plasticity of neuron-target contacts. Prog Neurobiol 1997; 52: 127-144.
41. Melillo RM, Barone MV, Lupoli G, et al. Ret-mediated mitogenesis requires src kinase activity. Cancer Res 1999; 59: 1120-1126.
42. Robles E, Woo S, Gomez TM. Src-dependent tyrosine phosphorylation at the tips of growth cone filopodia promotes extension. J Neurosci 2005; 25: 7669-7681.
43. Vaillancourt RR, Heasley LE, Zamarripa J, et al. Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation. Mol Cell Biol 1995; 15: 3644-3653.
44. Chierzi S, Ratto GM, Verma P, Fawcett JW. The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK. Eur J Neurosci 2005; 21: 2051-2062.
45. Waetzig V, Herdegen T. MEKK1 controls neurite regrowth after experimental injury by balancing ERK1/2 and JNK2 signaling. Mol Cell Neurosci 2005; 30: 67-78.
46. Higuchi M, Onishi K, Masuyama N, Gotoh Y. The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells. Genes Cells 2003; 8: 657-669.
47. Ramesh N, Antón IM, Martínez-Quiles N, Geha RS. Waltzing with WASP. Trends Cell Biol 1999; 9: 15-19.
48. Rohatgi R, Ma L, Miki H, et al. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell 1999; 97: 221-231.
49. Chang AN, Cantor AB, Fujiwara Y, et al. GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis. Proc Natl Acad Sci USA 2002; 99: 9237-9242.
50. Crispino JD, Lodish MB, MacKay JP, Orkin SH. Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: the GATA-1: FOG complex. Mol Cell 1999; 3: 219-228.
51. Freson K, Devriendt K, Matthijs G, et al. Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation. Blood 2001; 98: 85-92.
52. Olson MF, Pasteris NG, Gorski JL, Hall A. Faciogenital dysplasia protein(FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases. Curr Biol 1996; 6: 1628-1633.
53. Gillooly DJ, Simonsen A, Stenmark H. Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins. Biochem J 2001; 355: 249-258.
54. Pasteris NG, Nagata K, Hall A, Gorski JL. Isolation, characterization, and mapping of the mouse Fgd3 gene, a new faciogenital dysplasia (FGD1; Aarskog Syndrome) gene homologue. Gene 2000; 242: 237-247.
55. Ono Y, Nakanishi H, Nishimura M, et al. Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac. Oncogene 2000; 19: 3050-3058.
56. Abdelhaleem M. RNA helicases: regulators of differentiation. Clin Biochem 2005; 38: 499-503.