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Volumn 29, Issue 2, 2008, Pages 404-410

Stromal resistance of fibroblasts against oxidative damage: Involvement of tumor cell-secreted platelet-derived growth factor (PDGF) and phosphoinositide 3-kinase (PI3K) activation

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR;

EID: 40549138777     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm296     Document Type: Article
Times cited : (12)

References (67)
  • 1
    • 0037899253 scopus 로고    scopus 로고
    • Role of tissue stroma in cancer cell invasion
    • de Wever,O. et al. (2003) Role of tissue stroma in cancer cell invasion. J. Pathol., 200, 429-447.
    • (2003) J. Pathol , vol.200 , pp. 429-447
    • de Wever, O.1
  • 2
    • 12344328353 scopus 로고    scopus 로고
    • Tumor-stroma interactions
    • Bhowmick,N.A. et al. (2005) Tumor-stroma interactions. Curr. Opin. Genet. Dev., 15, 97-101.
    • (2005) Curr. Opin. Genet. Dev , vol.15 , pp. 97-101
    • Bhowmick, N.A.1
  • 3
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta,L.A. et al. (2001) The microenvironment of the tumour-host interface. Nature, 411, 375-379.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1
  • 4
    • 33746886564 scopus 로고    scopus 로고
    • Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species
    • Cat,B. et al. (2006) Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species. J. Cell Sci., 119, 2727-2738.
    • (2006) J. Cell Sci , vol.119 , pp. 2727-2738
    • Cat, B.1
  • 5
    • 33646384428 scopus 로고    scopus 로고
    • Kalluri,R. et al. (2066) Fibroblasts in cancer. Nat. Rev. Cancer, 6, 392-401.
    • Kalluri,R. et al. (2066) Fibroblasts in cancer. Nat. Rev. Cancer, 6, 392-401.
  • 6
    • 0342646934 scopus 로고    scopus 로고
    • Autocrine and paracrine regulation by cytokines and growth factors in melanoma
    • Lazar-Molnar,E. et al. (2000) Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine, 12, 547-554.
    • (2000) Cytokine , vol.12 , pp. 547-554
    • Lazar-Molnar, E.1
  • 7
    • 33745107179 scopus 로고    scopus 로고
    • A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes
    • Gotzmann,J. et al. (2006) A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes. Oncogene, 25, 3170-3185.
    • (2006) Oncogene , vol.25 , pp. 3170-3185
    • Gotzmann, J.1
  • 8
    • 2642574125 scopus 로고    scopus 로고
    • Paracrine effect of TGF-beta1 on downregulation of gap junctional intercellular communication between human dermal fibroblasts
    • Stuhlmann,D. et al. (2004) Paracrine effect of TGF-beta1 on downregulation of gap junctional intercellular communication between human dermal fibroblasts. Biochem. Biophys. Res. Commun., 319 321-326.
    • (2004) Biochem. Biophys. Res. Commun , vol.319 , pp. 321-326
    • Stuhlmann, D.1
  • 9
    • 0036005960 scopus 로고    scopus 로고
    • Role of myofibroblasts at the invasion front
    • de Wever,O. et al. (2002) Role of myofibroblasts at the invasion front. Biol. Chem., 383, 55-67.
    • (2002) Biol. Chem , vol.383 , pp. 55-67
    • de Wever, O.1
  • 10
    • 0034987702 scopus 로고    scopus 로고
    • Malignant glioma: Genetics and biology of a grave matter
    • Maher,E.A. et al. (2001) Malignant glioma: Genetics and biology of a grave matter. Genes Dev., 15, 1311-1333.
    • (2001) Genes Dev , vol.15 , pp. 1311-1333
    • Maher, E.A.1
  • 11
    • 33645287685 scopus 로고    scopus 로고
    • Akt/PKB signaling in cancer: A function in cell motility and invasion
    • Yoeli-Lerner,M. et al. (2006) Akt/PKB signaling in cancer: A function in cell motility and invasion. Cell Cycle, 5, 603-605.
    • (2006) Cell Cycle , vol.5 , pp. 603-605
    • Yoeli-Lerner, M.1
  • 12
    • 33744931651 scopus 로고    scopus 로고
    • Increased sensitivity to the platelet-derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF-BB-mediated signaling and STI571-induced Akt inactivation
    • Servidei,T. et al. (2006) Increased sensitivity to the platelet-derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF-BB-mediated signaling and STI571-induced Akt inactivation. J. Cell. Physiol., 208, 220-228.
    • (2006) J. Cell. Physiol , vol.208 , pp. 220-228
    • Servidei, T.1
  • 13
    • 33744903661 scopus 로고    scopus 로고
    • PTEN/Akt signaling through epidermal growth factor receptor is prerequisite for angiogenesis by hepatocellular carcinoma cells that is susceptible to inhibition by gefitinib
    • Ueda,S. et al. (2006) PTEN/Akt signaling through epidermal growth factor receptor is prerequisite for angiogenesis by hepatocellular carcinoma cells that is susceptible to inhibition by gefitinib. Cancer Res., 66, 5346-5353.
    • (2006) Cancer Res , vol.66 , pp. 5346-5353
    • Ueda, S.1
  • 14
    • 26444560222 scopus 로고    scopus 로고
    • Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways
    • Davies,M. et al. (2005) Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways. J. Cell. Biochem. 95, 918-931.
    • (2005) J. Cell. Biochem , vol.95 , pp. 918-931
    • Davies, M.1
  • 15
    • 0036116860 scopus 로고    scopus 로고
    • Tumor-associated fibroblasts (part II): Functional impact on tumor tissue
    • Kunz-Schughart,L.A. et al. (2002) Tumor-associated fibroblasts (part II): Functional impact on tumor tissue. Histol. Histopathol. 17, 623-637.
    • (2002) Histol. Histopathol , vol.17 , pp. 623-637
    • Kunz-Schughart, L.A.1
  • 16
    • 0027090432 scopus 로고    scopus 로고
    • Bayreuther,K. et al. (1992) Terminal differentiation, aging, apoptosis, and spontaneous transformation in fibroblast stem cell systems in vivo and in vitro. Ann. N. Y. Acad. Sci., 663 167-179.
    • Bayreuther,K. et al. (1992) Terminal differentiation, aging, apoptosis, and spontaneous transformation in fibroblast stem cell systems in vivo and in vitro. Ann. N. Y. Acad. Sci., 663 167-179.
  • 17
    • 0015759232 scopus 로고
    • In vitro cultivation of human tumors: Establishment of cell lines derived from a series of solid tumors
    • Giard,D.J. et al. (1973) In vitro cultivation of human tumors: Establishment of cell lines derived from a series of solid tumors. J. Natl Cancer Inst., 51, 1417-1423.
    • (1973) J. Natl Cancer Inst , vol.51 , pp. 1417-1423
    • Giard, D.J.1
  • 18
    • 0020084137 scopus 로고
    • Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin
    • Boukamp,P. et al. (1982) Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin. J. Natl Cancer Inst., 68, 415-427.
    • (1982) J. Natl Cancer Inst , vol.68 , pp. 415-427
    • Boukamp, P.1
  • 19
    • 0029990997 scopus 로고    scopus 로고
    • Multiparameter flow cytometric characterization of epidermal cell suspensions prepared from normal and hyperproliferative human skin using an optimized thermolysin-trypsin protocol
    • Glade,C.P. et al. (1996) Multiparameter flow cytometric characterization of epidermal cell suspensions prepared from normal and hyperproliferative human skin using an optimized thermolysin-trypsin protocol. Arch. Dermatol. Res., 288, 203-210.
    • (1996) Arch. Dermatol. Res , vol.288 , pp. 203-210
    • Glade, C.P.1
  • 20
    • 0021287698 scopus 로고
    • Rapid colorimetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines
    • Green,L.M. et al. (1984) Rapid colorimetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines. J. Immunol. Methods, 70, 257-268.
    • (1984) J. Immunol. Methods , vol.70 , pp. 257-268
    • Green, L.M.1
  • 21
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli,U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 22
    • 0022428152 scopus 로고
    • Oxidative stress: Damage to intact cells and organs
    • Sies,H. et al. (1985) Oxidative stress: Damage to intact cells and organs. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 311, 617-631.
    • (1985) Philos. Trans. R. Soc. Lond., B, Biol. Sci , vol.311 , pp. 617-631
    • Sies, H.1
  • 23
    • 84985570313 scopus 로고
    • Biochemistry of oxidative stress
    • Sies,H. (1986) Biochemistry of oxidative stress. Angew. Chem. Int. Ed. Engl., 25, 1058-1071.
    • (1986) Angew. Chem. Int. Ed. Engl , vol.25 , pp. 1058-1071
    • Sies, H.1
  • 24
    • 33845656037 scopus 로고    scopus 로고
    • Oxidative burst of neutrophils against melanoma B16-F10
    • Zivkovic,M. et al. (2007) Oxidative burst of neutrophils against melanoma B16-F10. Cancer Lett., 246, 100-108.
    • (2007) Cancer Lett , vol.246 , pp. 100-108
    • Zivkovic, M.1
  • 25
    • 34248396033 scopus 로고    scopus 로고
    • Dual role of hydrogen peroxide in cancer: Possible relevance to cancer chemoprevention and therapy
    • Lopez-Lazaro,M. (2007) Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy. Cancer Lett., 252, 1-8.
    • (2007) Cancer Lett , vol.252 , pp. 1-8
    • Lopez-Lazaro, M.1
  • 26
    • 0242392017 scopus 로고    scopus 로고
    • Modulation of homologous gap junctional intercellular communication of human dermal fibroblasts via a paracrine factors generated by squamous tumor cells
    • Stuhlmann,D. et al. (2003) Modulation of homologous gap junctional intercellular communication of human dermal fibroblasts via a paracrine factors generated by squamous tumor cells. Carcinogenesis, 24 1737-1748.
    • (2003) Carcinogenesis , vol.24 , pp. 1737-1748
    • Stuhlmann, D.1
  • 27
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta,S.R. et al. (1999) Cellular survival: A play in three Akts. Genes Dev., 13, 2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1
  • 28
    • 17144395975 scopus 로고    scopus 로고
    • The activation of Akt/PKB signaling pathway and cell survival
    • Song,G. et al. (2005) The activation of Akt/PKB signaling pathway and cell survival. J. Cell. Mol. Med., 9, 59-71.
    • (2005) J. Cell. Mol. Med , vol.9 , pp. 59-71
    • Song, G.1
  • 29
    • 0035920145 scopus 로고    scopus 로고
    • Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: Critical roles for kinase activity and amino acids arginine 211 and serine 343
    • Persad,S. et al. (2001) Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: Critical roles for kinase activity and amino acids arginine 211 and serine 343. J. Biol. Chem. 276, 27462-27469.
    • (2001) J. Biol. Chem , vol.276 , pp. 27462-27469
    • Persad, S.1
  • 30
    • 0029986938 scopus 로고    scopus 로고
    • Phosphoinositide kinases
    • Carpenter,C.L. et al. (1996) Phosphoinositide kinases. Curr. Opin. Cell Biol., 8, 153-158.
    • (1996) Curr. Opin. Cell Biol , vol.8 , pp. 153-158
    • Carpenter, C.L.1
  • 31
    • 0023245094 scopus 로고    scopus 로고
    • Coffey,R.J.Jr et al. (1987) Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2B cells. J. Cell. Physiol. 132, 143-148.
    • Coffey,R.J.Jr et al. (1987) Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2B cells. J. Cell. Physiol. 132, 143-148.
  • 32
    • 0024593227 scopus 로고
    • Suramin: An anticancer drug with a unique mechanism of action
    • Stein,C.A. et al. (1989) Suramin: An anticancer drug with a unique mechanism of action. J. Clin. Oncol., 7, 499-508.
    • (1989) J. Clin. Oncol , vol.7 , pp. 499-508
    • Stein, C.A.1
  • 33
    • 0025000170 scopus 로고
    • Suramin alters phosphoinositide synthesis and inhibits growth factor receptor binding in HT-29 cells
    • Kopp,R. et al. (1990) Suramin alters phosphoinositide synthesis and inhibits growth factor receptor binding in HT-29 cells. Cancer Res., 50, 6490-6496.
    • (1990) Cancer Res , vol.50 , pp. 6490-6496
    • Kopp, R.1
  • 34
    • 0029833752 scopus 로고    scopus 로고
    • Oxidative stress induces tyrosine phosphorylation of PDGF alpha-and beta-receptors and pp60c-src in mesangial cells
    • Gonzalez-Rubio,M. et al. (1996) Oxidative stress induces tyrosine phosphorylation of PDGF alpha-and beta-receptors and pp60c-src in mesangial cells. Kidney Int., 50, 164-173.
    • (1996) Kidney Int , vol.50 , pp. 164-173
    • Gonzalez-Rubio, M.1
  • 35
    • 0033061032 scopus 로고    scopus 로고
    • Protein tyrosine kinase inhibitors as novel therapeutic agents
    • Levitzki,A. (1999) Protein tyrosine kinase inhibitors as novel therapeutic agents. Pharmacol. Ther., 82, 231-239.
    • (1999) Pharmacol. Ther , vol.82 , pp. 231-239
    • Levitzki, A.1
  • 36
    • 0032546643 scopus 로고    scopus 로고
    • PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swine
    • Banai,S. et al. (1998) PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swine. Circulation, 97, 1960-1969.
    • (1998) Circulation , vol.97 , pp. 1960-1969
    • Banai, S.1
  • 37
    • 0033997473 scopus 로고    scopus 로고
    • Nanoparticulate delivery system of a tyrphostin for the treatment of restenosis
    • Fishbein,I. et al. (2000) Nanoparticulate delivery system of a tyrphostin for the treatment of restenosis. J. Control. Release, 65, 221-229.
    • (2000) J. Control. Release , vol.65 , pp. 221-229
    • Fishbein, I.1
  • 38
    • 33646067098 scopus 로고    scopus 로고
    • Involvement of selenoprotein P in protection of human astrocytes from oxidative damage
    • Steinbrenner,H. et al. (2006) Involvement of selenoprotein P in protection of human astrocytes from oxidative damage. Free Radic. Biol. Med., 40, 1513-1523.
    • (2006) Free Radic. Biol. Med , vol.40 , pp. 1513-1523
    • Steinbrenner, H.1
  • 39
    • 0027160663 scopus 로고
    • Relationship between the critical level of oxidative stresses and the glutathione peroxidase activity
    • Toussaint,O. et al. (1993) Relationship between the critical level of oxidative stresses and the glutathione peroxidase activity. Toxicology, 81, 89-101.
    • (1993) Toxicology , vol.81 , pp. 89-101
    • Toussaint, O.1
  • 40
    • 0348049803 scopus 로고    scopus 로고
    • Reactive oxygen species in oncogenic transformation
    • Behrend,L. et al. (2003) Reactive oxygen species in oncogenic transformation. Biochem. Soc. Trans., 31, 1441-1444.
    • (2003) Biochem. Soc. Trans , vol.31 , pp. 1441-1444
    • Behrend, L.1
  • 42
    • 33744962865 scopus 로고    scopus 로고
    • Redefining oxidative stress
    • Jones,D.P. (2006) Redefining oxidative stress. Antioxid. Redox Signal., 8, 1865-1879.
    • (2006) Antioxid. Redox Signal , vol.8 , pp. 1865-1879
    • Jones, D.P.1
  • 43
    • 0025987977 scopus 로고
    • Oxidative stress: From basic research to clinical application
    • Sies,H. (1991) Oxidative stress: From basic research to clinical application. Am. J. Med., 91, 31S-38S.
    • (1991) Am. J. Med , vol.91
    • Sies, H.1
  • 44
    • 33748165596 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer cells: Live by the sword, die by the sword
    • Schumacker,P.T. (2006) Reactive oxygen species in cancer cells: Live by the sword, die by the sword. Cancer Cell, 10, 175-176.
    • (2006) Cancer Cell , vol.10 , pp. 175-176
    • Schumacker, P.T.1
  • 45
    • 33748146888 scopus 로고    scopus 로고
    • Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate
    • Trachootham,D. et al. (2006) Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer Cell, 10, 241-252.
    • (2006) Cancer Cell , vol.10 , pp. 241-252
    • Trachootham, D.1
  • 46
    • 34248582844 scopus 로고    scopus 로고
    • Novel action of paclitaxel against cancer cells: Bystander effect mediated by reactive oxygen species
    • Alexandre,J. et al. (2007) Novel action of paclitaxel against cancer cells: Bystander effect mediated by reactive oxygen species. Cancer Res., 67, 3512-3517.
    • (2007) Cancer Res , vol.67 , pp. 3512-3517
    • Alexandre, J.1
  • 47
    • 23644441924 scopus 로고    scopus 로고
    • Enhancement of radiation-induced oxidative stress and cytotoxicity in tumor cells by ellagic acid
    • Bhosle,S.M. et al. (2005) Enhancement of radiation-induced oxidative stress and cytotoxicity in tumor cells by ellagic acid. Clin. Chim. Acta, 359, 89-100.
    • (2005) Clin. Chim. Acta , vol.359 , pp. 89-100
    • Bhosle, S.M.1
  • 48
    • 2442549623 scopus 로고    scopus 로고
    • Tumor intracellular redox status and drug resistance-serendipity or a causal relationship?
    • Pervaiz,S. et al. (2004) Tumor intracellular redox status and drug resistance-serendipity or a causal relationship? Curr. Pharm. Des. 10, 1969-1977.
    • (2004) Curr. Pharm. Des , vol.10 , pp. 1969-1977
    • Pervaiz, S.1
  • 49
    • 13544257464 scopus 로고    scopus 로고
    • Gefitinib therapy for non-small cell lung cancer
    • Birnbaum,A. et al. (2005) Gefitinib therapy for non-small cell lung cancer. Curr. Treat. Options Oncol., 6, 75-81.
    • (2005) Curr. Treat. Options Oncol , vol.6 , pp. 75-81
    • Birnbaum, A.1
  • 50
    • 0033712619 scopus 로고    scopus 로고
    • Gemcitabine and paclitaxel associated pneumonitis in non-small cell lung cancer: Report of a phase I/II dose-escalating study
    • Thomas,A.L. et al. (2000) Gemcitabine and paclitaxel associated pneumonitis in non-small cell lung cancer: Report of a phase I/II dose-escalating study. Eur J. Cancer, 36, 2329-2334.
    • (2000) Eur J. Cancer , vol.36 , pp. 2329-2334
    • Thomas, A.L.1
  • 51
    • 7944223434 scopus 로고    scopus 로고
    • Increased expression of antioxidant enzymes in radioresistant variant from U251 human glioblastoma cell line
    • Lee,H.C. et al. (2004) Increased expression of antioxidant enzymes in radioresistant variant from U251 human glioblastoma cell line. Int. J. Mol. Med., 13, 883-887.
    • (2004) Int. J. Mol. Med , vol.13 , pp. 883-887
    • Lee, H.C.1
  • 52
    • 0032030989 scopus 로고    scopus 로고
    • Role of antioxidant enzyme on ionizing radiation resistance
    • Sun,J. et al. (1998) Role of antioxidant enzyme on ionizing radiation resistance. Free Radic. Biol. Med., 24, 586-592.
    • (1998) Free Radic. Biol. Med , vol.24 , pp. 586-592
    • Sun, J.1
  • 53
    • 33745518361 scopus 로고    scopus 로고
    • Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells
    • Mochizuki,T. et al. (2006) Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells. Oncogene, 25, 3699-3707.
    • (2006) Oncogene , vol.25 , pp. 3699-3707
    • Mochizuki, T.1
  • 54
    • 33751170050 scopus 로고    scopus 로고
    • Inhibition of the CaM-kinases augments cell death in response to oxygen radicals and oxygen radical inducing cancer therapies in MCF-7 human breast cancer cells
    • Rodriguez-Mora,O.G. et al. (2006) Inhibition of the CaM-kinases augments cell death in response to oxygen radicals and oxygen radical inducing cancer therapies in MCF-7 human breast cancer cells. Cancer Biol. Ther., 5, 1022-1030.
    • (2006) Cancer Biol. Ther , vol.5 , pp. 1022-1030
    • Rodriguez-Mora, O.G.1
  • 55
    • 11144347718 scopus 로고    scopus 로고
    • Origins and evolution of cell phenotypes in breast tumors
    • Tozeren,A. et al. (2005) Origins and evolution of cell phenotypes in breast tumors. J. Theor Biol., 233, 43-54.
    • (2005) J. Theor Biol , vol.233 , pp. 43-54
    • Tozeren, A.1
  • 56
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin,C.H. et al. (1999) Mechanism of action and in vivo role of platelet-derived growth factor. Physiol. Rev., 79, 1283-1316.
    • (1999) Physiol. Rev , vol.79 , pp. 1283-1316
    • Heldin, C.H.1
  • 57
    • 0027361809 scopus 로고
    • Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells
    • Shamah,S.M. et al. (1993) Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells. Mol. Cell. Biol., 13, 7203-7212.
    • (1993) Mol. Cell. Biol , vol.13 , pp. 7203-7212
    • Shamah, S.M.1
  • 58
    • 10544233369 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor (PDGF)-A, PDGF-B and the PDGF-alpha receptor, but not the PDGF-beta receptor, in human malignant melanoma in vivo
    • Barnhill,R.L. et al. (1996) Expression of platelet-derived growth factor (PDGF)-A, PDGF-B and the PDGF-alpha receptor, but not the PDGF-beta receptor, in human malignant melanoma in vivo. Br. J. Dermatol., 135, 898-904.
    • (1996) Br. J. Dermatol , vol.135 , pp. 898-904
    • Barnhill, R.L.1
  • 59
    • 34250017806 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells
    • Lederle,W. et al. (2006) Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells. Am. J. Pathol., 169, 1767-1783.
    • (2006) Am. J. Pathol , vol.169 , pp. 1767-1783
    • Lederle, W.1
  • 60
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: Navigating downstream
    • Manning,B.D. et al. (2007) AKT/PKB signaling: Navigating downstream. Cell, 129, 1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1
  • 61
    • 20344396383 scopus 로고    scopus 로고
    • Different activation of mitogen-activated protein kinase and Akt signaling is associated with aggressive phenotype of human meningiomas
    • Mawrin,C. et al. (2005) Different activation of mitogen-activated protein kinase and Akt signaling is associated with aggressive phenotype of human meningiomas. Clin. Cancer Res., 11, 4074-4082.
    • (2005) Clin. Cancer Res , vol.11 , pp. 4074-4082
    • Mawrin, C.1
  • 62
    • 21544483506 scopus 로고    scopus 로고
    • Functional and therapeutic significance of Akt deregulation in malignant melanoma
    • Robertson,G.P. (2005) Functional and therapeutic significance of Akt deregulation in malignant melanoma. Cancer Metastasis Rev., 24 273-285.
    • (2005) Cancer Metastasis Rev , vol.24 , pp. 273-285
    • Robertson, G.P.1
  • 63
    • 0034888532 scopus 로고    scopus 로고
    • Role of phosphoinositide 3OH-kinase in autocrine transformation by PDGF-BB
    • Rosenmuller,T. et al. (2001) Role of phosphoinositide 3OH-kinase in autocrine transformation by PDGF-BB. J. Cell. Physiol., 188 369-382.
    • (2001) J. Cell. Physiol , vol.188 , pp. 369-382
    • Rosenmuller, T.1
  • 64
    • 14944381154 scopus 로고    scopus 로고
    • PI3K/AKT is involved in mediating survival signals that rescue Ewing tumour cells from fibroblast growth factor 2-induced cell death
    • Hotfilder,M. et al. (2005) PI3K/AKT is involved in mediating survival signals that rescue Ewing tumour cells from fibroblast growth factor 2-induced cell death. Br. J. Cancer, 92, 705-710.
    • (2005) Br. J. Cancer , vol.92 , pp. 705-710
    • Hotfilder, M.1
  • 65
    • 29344435297 scopus 로고    scopus 로고
    • Tea polyphenol epigallocatechin 3-gallate impedes the anti-apoptotic effects of low-grade repetitive stress through inhibition of Akt and NFkappaB survival pathways
    • Sen,P. et al. (2006) Tea polyphenol epigallocatechin 3-gallate impedes the anti-apoptotic effects of low-grade repetitive stress through inhibition of Akt and NFkappaB survival pathways. FEBS Lett. 580, 278-284.
    • (2006) FEBS Lett , vol.580 , pp. 278-284
    • Sen, P.1
  • 66
    • 20144371449 scopus 로고    scopus 로고
    • Deletion of the PDGFR-beta gene affects key fibroblast functions important for wound healing
    • Gao,Z. et al. (2005) Deletion of the PDGFR-beta gene affects key fibroblast functions important for wound healing. J. Biol. Chem., 280, 9375-9389.
    • (2005) J. Biol. Chem , vol.280 , pp. 9375-9389
    • Gao, Z.1
  • 67
    • 33645458952 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: Modulatory effect of cellular G6PD status
    • Ho,H.Y. et al. (2006) Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: Modulatory effect of cellular G6PD status. J. Agric. Food Chem., 54, 1638-1645.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 1638-1645
    • Ho, H.Y.1


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