Atypical cytostatic mechanism of N-1-sulfonylcytosine derivatives determined by in vitro screening and computational analysis

Investigational New Drugs

Volumn 26, Issue 2, 2008, Pages 97-110

  Supek, Fran ^a   Kralj, Marijeta ^a   Marjanović, Marko ^a   Šuman, Lidija ^a   Šmuc, Tomislav ^a   Krizmanić, Irena ^b,c   Žinić, Biserka ^a  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b HERBOS Chem Industry   (Croatia)

^c PLIVA CROATIA LTD   (Croatia)

Author keywords

Antitumor agents; Bioinformatics; In vitro screening; Nucleobases; Random Forest

Indexed keywords

1 (4 TOLUENESULFONYL)CYTOSINE; CISPLATIN; COLCHICINE; CYTARABINE; CYTOSINE DERIVATIVE; ETOPOSIDE; FLUOROURACIL; HYDROXYUREA; METHOTREXATE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOINFORMATICS; CANCER INHIBITION; CELL CYCLE; CELL LINE; CONTROLLED STUDY; CYTOSTASIS; DRUG ACTIVITY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; RANDOM FOREST;

EID: 40549130066     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-007-9084-1     Document Type: Article

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