Tempol improves renal hemodynamics and pressure natriuresis in hyperthyroid rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 294, Issue 3, 2008, Pages

  Moreno, Juan Manuel ^a   Gómez, Isabel Rodríguez ^b   Wangensteen, Rosemary ^b   Alvarez Guerra, Miriam ^b   Luna, Juan De Dios ^b   García Estañ, Joaquín ^c,d   Vargas, Félix ^b  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

^c UNIVERSITY OF JAÉN   (Spain)

^d UNIVERSITY OF MURCIA   (Spain)

Author keywords

Glomerular filtration rate; Hyperthyroidism; Renal blood flow

Indexed keywords

8 ISOPROSTANE; TEMPOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; GLOMERULUS FILTRATION RATE; HYPERTHYROIDISM; KIDNEY BLOOD FLOW; KIDNEY PERFUSION; KIDNEY TUBULE PRESSURE; KIDNEY VASCULAR RESISTANCE; MEAN ARTERIAL PRESSURE; NATRIURESIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SODIUM EXCRETION;

ANIMALS; ANTIOXIDANTS; BLOOD PRESSURE; CYCLIC N-OXIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLOMERULAR FILTRATION RATE; HEART RATE; HYPERTENSION; HYPERTHYROIDISM; MALE; NATRIURESIS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RENAL CIRCULATION; SPIN LABELS; THYROXINE; VASCULAR RESISTANCE;

EID: 40449088287     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00665.2007     Document Type: Article

References (40)

1. Beswick RA, Zhang H, Marabe D, Catravas JD, Hill WD, Webb RC. Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response. Hypertension 37: 781-786, 2001.
2. 1) receptor blockade in low-renin deoxycorticosterone acetate (DOCA)-treated spontaneously hypertensive rats. Clin Sci 106: 251-259, 2004.
3. Cowley AW Jr. Role of renal medulla in volume and arterial pressure regulation. Am J Physiol Regul Integr Comp Physiol 273: R1-R15, 1997.
4. Cowley AW. Long-term control of arterial pressure. Physiol Rev 72: 211-300, 1992.
5. Dutta UK, Jason Lane Roberts LJ, II, Majid DSA. Superoxide formation and interaction with nitric oxide modulate systemic arterial pressure and renal function in Salt-Depleted Dogs. Exp Biol Med 231: 269-276, 2006.
6. Esterbauer H, Cheeseman KH. Determination of aldehydic lipid peroxidation product: malonaldehyde and 4-hydroxynonenal. Methods Enzymol 186: 407-421, 1990.
7. Evans RG, Fitzgerald SM. Nitric oxide and superoxide in the renal medulla: a delicate balancing act. Curr Opin Nephrol Hypertens 14: 9-15, 2005.
8. Fam SS, Morrow JD. The isoprostanes: unique products of arachidonic acid oxidation-a review. Curr Med Chem 10: 1723-1740, 2003.
9. Feng MG, Dukacz SA, Kline RL. Selective effect of tempol on renal medullary hemodynamics in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol 281: R1420-R1425, 2001.
10. García del Río C, Moreno MR, Osuna A, Luna JD, García-Estañ J, Vargas F. Role of the renin-angiotensin system in the development of thyroxine-induced hypertension. Eur J Endocrinol 136: 656-660, 1997.
11. García-Estañ J, Atucha N, Quesada T, Vargas F. Involvement of the renin-angiotensin system in the reduced pressure-natriuresis response of hyperthyroid rats. Am J Physiol Endocrinol Metab 268: E897-E901, 1995.
12. Garvin JL, Ortiz PA. The role of reactive oxygen species in the regulation of tubular function. Acta Physiol Scand 179: 225-232, 2003.
13. Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86: 494-501, 2000.
14. Klein I. Thyroid hormone and the cardiovascular system. Am J Med 88: 631-637, 1990.
15. Kopkan L, Castillo A, Navar LG, Majid DSA. Enhanced superoxide generation modulates renal function in ANG II-induced hypertensive rats. Am J Physiol Renal Physiol 290: F80-F86, 2006.
16. Kopkan L, Majid DSA. Enhanced superoxide activity modulates renal function in NO-deficient hypertensive rats. Hypertension 47: 568-572, 2006.
17. Larsen PR, Davis TF, Hay ID. The thyroid gland. In: Williams Textbook of Endocrinology (6th ed.), edited by Wilson JD, Foster DW, Kronenberg HK, and Larsen PR. London: Saunders, 1998, p. 389-515.
18. Levey GS. Catecholamine sensitivity, thyroid hormone and the heart. Am J Med 50: 413-420, 1971.
19. Lopez B, Salom MG, Arregui B, Valero F, Fenoy FJ. Role of superoxide in modulating the renal effects of angiotensin II. Hypertension 42: 1150-1156, 2003.
20. + channels in the rat CCD. Am J Physiol Cell Physiol 275: C309-C316, 1998.
21. Majid DS, Nishiyama A, Jackson KE, Castillo A. Inhibition of nitric oxide synthase enhances superoxide activity in canine kidney. Am J Physiol Regul Integr Comp Physiol 287: R27-R32, 2004.
22. Mitchell JB, Samuni A, Krishna MC, DeGraff WG, Ahn MS, Samuni U, Russo A. Biologically active metal-independent superoxide dismutase mimetics. Biochemistry 29: 2802-2807, 1990.
23. Moreno JM, Rodríguez-Gómez I, Wangensteen R, Osuna A, Bueno P, Vargas F. Cardiac and renal antioxidant enzymes and effects of tempol in hyperthyroid rats. Am J Physiol Endocrinol Metab 289: E776-E783, 2005.
24. Mori T, Cowley AW Jr. Renal oxidative stress in medullary thick ascending limbs produced by elevated NaCl and glucose. Hypertension 43: 341-346, 2004.
25. - and NO in the thick ascending limb. Hypertension 39: 591-596, 2002.
26. Ortiz PA, Garvin JL. Superoxide stimulates NaCl absorption in the thick ascending limb. Am J Physiol Renal Physiol 283: F957-F962, 2002.
27. Rodríguez-Gómez I, Sainz J, Wangensteen R, Moreno JM, Duarte J, Osuna A, Vargas F. Increased pressor sensitivity to chronic nitric oxide deficiency in hyperthyroid rats. Hypertension 42: 220-225, 2003.
28. Sainz J, Wangensteen R, Rodríguez-Gómez I, Moreno JM, Chamorro V, Osuna A, Bueno P, Vargas F. Antioxidant enzymes and effects of tempol, a membrane permeable radical scavenger, on the development of NO inhibition induced-hypertension. Am J Hypertens 18: 871-877, 2005.
29. Schnackenberg CG, Welch WJ, Wilcox CS. Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: role of nitric oxide. Hypertension 32: 59-64, 1998.
30. 2α. Hypertension 33: 424-428, 1999.
31. Shokoji T, Nishiyama A, Fijisawa Y, Hitomi H, Kiyomoto H, Takahashi N, Kimura S, Kohno M, Abe Y. Renal sympathetic nerve responses to tempol in spontaneously hypertensive rats. Hypertension 41: 266-273, 2003.
32. Vargas F, Atucha N, Sabio JM, Quesada T, García-Estañ J. Pressure-diuresis-natriuresis response in hyper- and hypothyroid rats. Clin Sci 87: 323-328, 1994.
33. Vargas F, Baz MJ, Luna JD, Andrade J, Jodar E, Haro JM. Urinary excretion of digoxin-like immunoreactive factor and arginine vasopressin in hyper- and hypothyroid rats. Clin Sci 81: 471-476, 1991.
34. Vargas F, Fernández-Rivas A, García-Estañ J, García del Río C. Endothelium-dependent and endothelium-independent vasodilation in hyperthyroid and hypothyroid rats. Pharmacology 51: 308-314, 1995.
35. Vargas F, García del Río C, Luna JD, Haro JM. Osorio C. Studies on thyroid activity in deoxycorticosterone-salt and Goldblatt two-kidney, one-clip hypertensive rats. Acta Endocrinol 118: 22-30, 1988.
36. Vargas F, Moreno JM, Rodríguez-Gómez I, Wangensteen R, Alvarez-Guerra M, Osuna A, García-Estañ J. Vascular and renal function in experimental thyroid disorders. Eur J Endocrinol 154: 197-212, 2006.
37. Vaziri ND. Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension. Curr Opin Nephrol Hypertens 13: 93-99, 2004.
38. Welch WJ, Tojo A, Wilcox CS. Roles of NO and oxygen radicals in tubuloglomerular feed-back in SHR. Am J Physiol Renal Physiol 278: F769-F776, 2000.
39. Wilcox CS. Reactive oxygen species: roles in blood pressure and kidney function. Curr Hypertens Rep 4: 160-166, 2002.
40. Zou AP, Li N, Cowley AW Jr. Production and action of superoxide in renal medulla. Hypertension 37: 547-553, 2001.