Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response

Hypertension

Volumn 37, Issue 2 II, 2001, Pages 781-786

  Beswick, Richard A ^a,b   Zhang, Hanfang ^a   Marable, Dawnyetta ^c   Catravas, John D ^a   Hill, William D ^a   Clinton Webb, R ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c FORT VALLEY STATE UNIVERSITY   (United States)

Author keywords

Hypertension; Mineralocorticoid; Monocyte macrophage; Nuclear factor B; Pyrrolidinedithiocarbamate; Tempol

Indexed keywords

ANTIOXIDANT; DEOXYCORTICOSTERONE ACETATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MINERALOCORTICOID; PYRROLIDINEDITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TEMPOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; BLOOD PRESSURE REGULATION; CELL INFILTRATION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG PROTEIN BINDING; HYPERTENSION; IMMUNOPATHOLOGY; MACROPHAGE ACTIVATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RENOVASCULAR HYPERTENSION; SYSTOLIC BLOOD PRESSURE;

EID: 0035095743     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.37.2.781     Document Type: Conference Paper

References (31)

1. Remodeling of the rat right and left ventricle in experimental hypertension
2. Studies on the mechanism of glucocorticoid hypertension in humans
3. Vascular superoxide production and vasomotor function in hypertension induced by deoxy-corticosterone acetate-salt
4. Oxidative stress in the Dahl hypertensive rat
5. Superoxide anion production is increased in a model of genetic hypertension
6. Oxidative stress and nuclear factor-κB activation
7. Mechanism of disease: Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
8. Mechanism of disease: Atherosclerosis: An inflammatory disease
9. Evidence for activation of endothelium and monocytes in hypertensive rats
10. Oxidative stress and gene regulation
11. Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats
12. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: Contribution to alteration of vasomotor tone
13. NF-κB inhibition ameliorates angiotensin II-induced inflammatory damage in rats
14. Lead-induced hypertension: Interplay of nitric oxide and reactive oxygen species
15. 2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
16. 2
17. Effects of tempol, a membrane permeable radical scavenger, in a gerbil model of brain injury
18. Inhibition of oxygen dependent radiation-induced damage by nitroxide superoxide dismutase mimetic, tempol
19. Oxygen free radicals in essential hypertension
20. NF-κB inhibition lowers blood pressure in mineralocorticoid hypertensive rats
21. Hypercholesterolemia increases endothelial superoxide anion production
22. Dietary correction of hypercholesterolemia in the rabbit normalizes endothelial superoxide anion production
23. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems
24. Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: Evidence for involvement of the renin-angiotensin system
25. Different mechanisms control signal-induced degradation and basal turnover of the NF-κB inhibitor 1κβα in vivo
26. Non-NF-κB elements are required for full induction of the rat type II nitric oxide synthase in vascular smooth muscle cells
27. Interaction between NO and reactive oxygen species: Pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure
28. NAD(P)H oxidase role in cardiovascular biology and disease
29. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
30. Hypertension-induced end-organ damage: A new transgenic approach to an old problem
31. Are renal hemodynamics a key factor in the development and maintenance of arterial hypertension?