Expression and enzyme activity determination of human cyclooxygenase-1 and -2 in a baculovirus-insect cell system

Acta Pharmacologica Sinica

Volumn 25, Issue 8, 2004, Pages 1000-1006

  Zhang, Wei Yu ^a   Yang, Xin Ning ^a,b   Jin, Dao Zhong ^a   Zhu, Xing Zu ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

Baculoviruses; Drug inhibition; Non steroidal anti inflammatory agents, prostaglandins; Prostaglandin endoperoxide synthase

Indexed keywords

ARACHIDONIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DICLOFENAC; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2;

ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INSECT CELL; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BACULOVIRIDAE; CELL LINE, TUMOR; CELLS, CULTURED; CLONING, MOLECULAR; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INDOMETHACIN; ISOENZYMES; LEUKEMIA, MYELOID; MEMBRANE PROTEINS; NITROBENZENES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECOMBINANT PROTEINS; SPODOPTERA; SULFONAMIDES;

EID: 4043166950     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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