Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids

Journal of Endocrinology

Volumn 182, Issue 1, 2004, Pages 11-21

  Robichaud, M ^a   Debonnel, Guy ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 METHOXY 3 (2 PHENYLETHOXY)PHENYL] N,N DIPROPYLETHYLAMINE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3BETA HYDROXY 5ALPHA PREGNAN 20 ONE; 5ALPHA PREGNANE 3,20 DIONE; ANTIDEPRESSANT AGENT; ELTANOLONE; FINASTERIDE; NEUROSTEROID; PRASTERONE; PREGNANEDIONE; PREGNENOLONE; PROGESTERONE; SEROTONIN; TRILOSTANE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DORSAL RAPHE NUCLEUS; DOSE RESPONSE; DRUG EFFECT; DRUG STRUCTURE; EVIDENCE BASED MEDICINE; FEMALE; IN VIVO STUDY; MOOD DISORDER; NERVE CELL MEMBRANE POTENTIAL; NEUROMODULATION; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT; SEROTONINERGIC NERVE CELL; SEROTONINERGIC SYSTEM; SEX DIFFERENCE;

5-ALPHA-DIHYDROPROGESTERONE; ANIMALS; ANISOLES; ANTIPSYCHOTIC AGENTS; DEHYDROEPIANDROSTERONE; DIHYDROTESTOSTERONE; FEMALE; FINASTERIDE; GENDER IDENTITY; GONADAL STEROID HORMONES; NEURONS; OVARIECTOMY; PREGNENOLONE; PROGESTERONE; PROPYLAMINES; PROTEIN ISOFORMS; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SIGMA; SEROTONIN; SYNAPTIC TRANSMISSION; TIME FACTORS;

EID: 4043114928     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1820011     Document Type: Article

References (62)

1. Armitage M, Nooney JM & Evans S 2003 Recent concerns surrounding HRT. Clinical Endocrinology 59 145-155.
2. Bergeron R, De Montigny C & Debonnel G 1996 Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. Journal of Neuroscience 16 1193-1202.
3. Bermack JE & Debonnel G 2001 Modulation of serotonergic neurotransmission by short- and long-term treatments with sigma ligands. British Journal of Pharmacology 134 691-699.
4. Bethea CL, Pecins-Thompson M, Schutzer WE, Gundlah C & Lu ZN 1999 Ovarian steroids and serotonin neural function. Molecular Neurobiology 18 87-123.
5. A receptor function. Pharmacology, Biochemistry, and Behavior 45 423-428.
6. Blier P & de Montigny C 1999 Serotonin and drug-induced therapeutic responses in major depression, obsessive-compulsive and panic disorders. Neuropsychopharmacology 21 91S-98S.
7. Celotti F, Melcangi RC & Martini L 1992 The 5α-reductase in the brain: molecular aspects and relation to brain function. Frontiers in Neuroendocrinology 13 163-215.
8. Compagnone NA & Mellon SH 2000 Neurosteroids: biosynthesis and function of these novel neuromodulators. Frontiers in Neuroendocrinology 21 1-56.
9. Concas A, Mostallino MC, Porcu P, Follesa P, Barbaccia ML, Trabucchi M, Purdy RH, Grisenti P & Biggio G 1998 Role of brain allopregnanolone in the plasticity of γ-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery. PNAS 95 13284-13289.
10. Corpéchot C, Young J, Calvel C, Veltz JN, Touyer G, Mouren M, Prasad VVK, Banner C, Sjovall J, Baulieu EE & Robel P 1993 Neurosteroids: 3α-hydroxy-5α-pregnan-20-one and its precursors in the brain, plasma, and steroidogenic glands of male andfemale rats. Endocrinology 133 1003-1009.
11. 3 region of the rat dorsal hippocampus: an effect mediated via sigma receptors. Journal of Endocrinology 150 S33-S42.
12. Dong E, Matsumoto K, Uzunova V, Sugaya I, Takahata H, Nomura H, Watanabe H, Costa E & Guidotti A 2001 Brain 5α -dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation. PNAS 98 2849-2854.
13. Endicott J 1993 The menstrual cycle and mood disorders. Journal of Affective Disorders 29 193-200.
14. A receptor regulation: chronic treatment with pregnanolone uncouples allosteric interactions between steroid and benzodiazepine recognition sites. Molecular Pharmacology 44 191-197.
15. Gervasoni D, Peyron C, Rampon C, Barbagli B, Chouvet G, Urbain N, Fort P & Luppi P-H 2000 Role and origin of the GABAergic innervation of dorsal raphe nucleus serotonergic neurons. Journal of Neuroscience 20 4217-4225.
16. Griffin LD & Mellon SH 1999 Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. PNAS 96 13512-13517.
17. 4-isomerase (3β-HSD), is expressed in rat brain. Molecular Brain Research 30 287-300.
18. A receptor subunit levels in association with increased anxiety in the female rat. Brain Research 910 55-66.
19. Hamilton JA 1993 Special aspects of neuropsychiatric illness in women: with a focus on depression. Annual Reviews of Medicine 44 355-364.
20. A receptor complex. Journal of Pharmacology and Experimental Therapeutics 241 346-353.
21. B receptor-mediated inhibition of serotonergic neurons. European Journal of Pharmacology 143 195-204.
22. Joffe H & Cohen LS 1998 Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge. Biological Psychiatry 44 798-811.
23. Kaminska M, Harris J, Gijsbers K & Dubrovsky B 2000 Dehydroepiandrosterone sulfate (DHEAS) counteracts decremental effects of corticosterone on dentate gyrus LTP. Implications for depression. Brain Research Bulletin 52 229-234.
24. Karavolas HJ & Hodges DR 1991 Metabolism of progesterone and related steroids by neural and neuroendocrine structures. In Neurosteroids and Brain Functions, pp 135-145. Eds E Costa & SM Paul. New York: Theine.
25. Karishma KK & Herbert J 2002 Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone-induced suppression. European Journal of Neuroscience 16 445-453.
26. 3 H to 5β-pregnane-3,20-dione by brain tissue. Steroids 25 459-463.
27. Kessler RC, Mcgonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen H-U & Kendler KS 1994 Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the united states. Archives of General Psychiatry 51 8-19.
28. Klink R, Robichaud M & Debonnel G 2002 Gender and gonadal status modulation of dorsal raphe nucleus serotonergic neurons. Part I: Effects of gender and pregnancy. Neuropharmacology 43 1119-1128.
29. Korneyev A, Guidotti A & Costa E 1993 Regional and interspecies differences in brain progesterone metabolism. Journal of Neurochemistry 61 2041-2047.
30. Kornstein SG 1997 Gender differences in depression: implications for treatment. Journal of Clinical Psychiatry 58 12-18.
31. A receptor modulators. American Journal of Physiology 271 E763-E772.
32. Maes M, De Ruyter M, Hobin P & Suy E 1986 The dexamethasone suppression test, the Hamilton depression rating scale and the DSM-III depression categories. Journal of Affective Disorders 10 207-214.
33. McCauley LD, Liu V, Chen J-S, Hawkinson JE, Lan NC & Gee KW 1995 Selective actions of certain neuroactive pregnanediols at the γ-aminobutyric acid type A receptor complex in rat brain. Molecular Pharmacology 47 354-362.
34. McEwen BS, Alves SE, Bulloch K & Weiland NG 1998 Clinically relevant basic science studies of gender differences and sex hormone effects. Psychopharmacology Bulletin 34 251-259.
35. Micevych P, Sinchak K, Mills RH, Tao L, Lapolt P & Lu JKH 2003 The luteinizing hormone surge is preceded by an estrogen-induced increase of hypothalamic progesterone in ovariectomized and adrenalectomized rats. Neuroendocrinology 78 29-35.
36. Morrow AL, Pace JR, Purdy RH & Paul SM 1989 Characterization of steroid interactions with γ-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites. Molecular Pharmacology 37 263-270.
37. Nappi RE, Petraglia F, Luisi S, Polatti F, Farina C & Genazzani AR 2001 Serum allopregnanolone in women with postpartum 'blues'. Obstetrics and Gynecology 97 77-80.
38. Pajer KP 1995 New strategies in the treatment of depression in women. Journal of Clinical Psychiatry 56 30-37.
39. Parry BL 1989 Reproductive factors affecting the course of affective illness in women. Psychiatric Clinics of North America 12 207-220.
40. 1 receptor-mediated behaviour in mice. European Journal of Neuroscience 11 2385-2396.
41. Potts GO, Creange JE, Harding HR & Schane HP 1978 Trilostane, an orally active inhibitor of steroid biosynthesis. Steroids 32 257-267.
42. A receptors. Neuron 4 759-765.
43. Racagni G & Brunello N 1999 Physiology to functionality: the brain and neurotransmitter activity. International Journal of Psychopharmacology 14 S3-S7.
44. Rapkin AJ, Morgan M, Goldman L, Brann DW, Simone D & Mahesh VB 1997 Progesterone metabolite allopregnanolone in women with premenstrual syndrome. Obstetrics and Gynecology 90 709-714.
45. 1) receptor mediated antidepressant-like effects of neurosteroids in the Porsolt forced swim test. Neuroreport 9 3069-3073.
46. Robichaud M, Klink R & Debonnel G 2002 Gender and gonadal status modulation of dorsal raphe nucleus serotonergic neurons. Part II: Regulatory mechanisms. Neuropharmacology 43 1129-1138.
47. Romeo E, Ströhle A, Spalletta G, Di Michele F, Hermann B, Holsboer F, Pasini A & Rupprecht R 1998 Effects of antidepressant treatment on neuroactive steroids in major depression. American Journal of Psychiatry 155 910-913.
48. Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, Dulawa S, Weisstaub N, Lee J, Duman R, Arancio O, Belzung C & Hen R 2003 Requirements of hippocampal neurogenesis for the behavioral effects of antidepressants: Science 301 805-809.
49. Serra M, Pisu MG, Muggironi M, Parodo, V, Papi G, Sari R, Dazzi L, Spiga F, Purdy RH & Biggio G 2001 Opposite effects of short-versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain. Psychopharmacology 158 48-54.
50. Smith D & Gallager DW 1987 GABA, benzodiazepine and serotonergic receptor development in the dorsal raphe nucleus: electrophysiological studies. Brain Research 432 191-198.
51. Ströhle A, Romeo E, Hermann B, Pasini A, Spalletta G, Di Michele F, Holsboer F & Rupprecht R 1999 Concentrations of 3α -reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery. Biological Psychiatry 45 274-277.
52. Urani A, Roman FJ, Phan V-L, Su T-P & Maurice T 2001 The antidepressant-like effect induced by sigma(1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test. Journal of Pharmacology and Experimental Therapeutics 298 1269-1279.
53. Uzunov DP, Cooper TB, Costa E & Guidotti A 1996 Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography. PNAS 93 12599-12604.
54. Uzunova V, Sheline Y, Davis JM, Rasmusson A, Uzunov DP, Costa E & Guidotti A 1998 Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. PNAS 95 3239-3244.
55. Weissman MM & Klerman GL 1977 Sex differences and the epidemiology of depression. Archives of General Psychiatry 34 98-111.
56. Weissman MM & Klerman GL 1985 Gender and depression. Trends in Neuroscience 8 416-420.
57. Weissman MM, Bland RC, Canino GJ, Faravelli C, Greenwald S, Hwu H-G, Joyce PR, Karam EG, Lee C-K, Lellouch J, Lépine J-P, Newman SC, Rubio-Stipec M, Wells JE, Wickramaratne PJ, Wittchen H-U & Yeh E-K 1996 Cross-national epidemiology of major depression and bipolar disorder. Journal of the American Medical Association 276 293-299.
58. Wolkowitz OM, Reus VI, Roberts E, Manfredi F, Chan T, Raum WJ, Orniston S, Johnson R, Canick J, Brizendine L & Weingartner H 1997 Dehydroepiandrosterone (DHEA) treatment of depression. Biological Psychiatry 41 305-310.
59. Young J, Corpéchot C, Perché F, Haug M, Baulieu EE & Robel P 1994 Neurosteroids: pharmacological effects of a 3β-hydroxysteroid dehydrogenase inhibitor. Endocrine 2 505-509.
60. Yu R & Ticku MK 1995a Chronic neurosteroid treatment produces functional heterologous uncoupling at the γ-aminobutyric acid type A/benzodiazepine receptor complex in mammalian cortical neurons. Molecular Pharmacology 47 603-610.
61. A receptor complex in mammalian cortical neurons. Journal of Pharmacology and Experimental Therapeutics 275 784-789.
62. A response and its potentiation by modulators in cortical neurons. Brain Research 706 160-162.