Dehydroepiandrosterone sulfate (DHEAS) counteracts decremental effects of corticosterone on dentate gyrus LTP. implications for depression

Brain Research Bulletin

Volumn 52, Issue 3, 2000, Pages 229-234

  Kaminska, M ^a   Harris, J ^a   Gijsbers, K ^b   Dubrovsky, B ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF STIRLING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; PRASTERONE SULFATE; SIGMA OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; DEPRESSION; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ACTION POTENTIALS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CORTICOSTERONE; DEHYDROEPIANDROSTERONE SULFATE; DENTATE GYRUS; DEPRESSION; EXCITATORY POSTSYNAPTIC POTENTIALS; LONG-TERM POTENTIATION; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034059006     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(00)00251-3     Document Type: Article

References (74)

1. Armstrong E. The limbic system and culture. Hum. Nat. 2:1991;117-136.
2. Backstrom T., Dubrovsky B., Landgren S. Brain excitability, steroid hormones, and menstrual cycle. Dennerstein I., Fraser T. Hormones and behavior. 1986;137-142 Elsevier, New York.
3. Baulieu E.E., Robel P. Dehydroepiandrosterone and dehydro-epiandrosterone sulfate as neuroactive neurosteroids. J. Endocrinol. 150:1996;S221-S239.
4. Bennett M.C., Diamond D.M., Fleshner M., Rose G.M. Serum corticosterone level predicts the magnitude of hippocampal primed burst potentiation and depression in urethane-anesthetized rats. Psychobiology. 19:1991;301-307.
5. Bliss T.V.P., Collingridge G.L. A synaptic model of memory Long term potentiation in the hippocampus . Nature. 31:1993;361.
6. Bloch M., Schmidt P.J., Danaceau M.A., Adams L.F., Rubinow D.R. Dehydroepiandrosterone treatment of midlife dysthymia. Biol. Psychiatry. 45:1999;1533-1541.
7. Browne E.C., Wright B.E., Porter J.R., Svec F. Dehydroepiandrosterone anti-glucocorticoid action in mice. Ann. J. Med. Sci. 303:1992;366-374.
8. Carette B., Poulain P. Excitatory effect of dihydroepiandro-sterone, its sulfate ester and pregnenolone sulfate, applied by iontophoresis and pressure on single neurons in the septopreoptic area of the guineau pig. Neurosci. Lett. 45:1984;205-210.
9. Chen Y.Z., Hua S.Y., Wang C.A., Wu L., Gu Q., Xing B.R. An electrophysiological study on the membrane receptor-mediated action of glucocorticoid in mammalian neurons. Neuroendocrinology. 53:1991;25-34.
10. Csaba G. Hormonal regulation. Morphogenetic and adaptive systems. Biol. Rev. 52:1977;295-303.
11. Csaba G. Phylogeny and ontogeny of hormone receptors The selection theory of receptor formation and hormonal imprinting . Biol. Rev. 55:1980;47-56.
12. Diamond D.M., Fleshner M., Rose Y. Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats. Behav. Brain Res. 62:1994;1-9.
13. Diamond D.M., Branch B.J., Fleshner M. The neurosteroid dehydroepiandrosterone sulfate (DHEAS) enhances hippocampal primed burst, but not long term potentiation. Neurosci. Lett. 202:1996;204-208.
14. Dubrovsky B., Williams D., Kraulis I. Effects of corticosterone and 5α dihydrocorticosterone on brain excitability in the rat. J. Neurosci. Res. 14:1985;118-127.
15. Dubrovsky B., Liquornik M., Noble P., Gijsbers K. Effects of 5α dihydrocorticosterone on evoked potentials and long term potentiation. Brain Res. Bull. 19:1987;635.
16. Dubrovsky, B.; Filipini, D. L.; Gijsbers, K.; Birmingham, M. K. Early and late effects of steroid hormones on the nervous system. In: Steroids and neural activity: Ciba Foundation Symposium (153). Chichester: Wiley; 1990:240-257.
17. Dubrovsky B. Adrenal steroids and the pathophysiology of a subset of depressive patients. J. Psychiatry Neurosci. 18:1993;1-13.
18. Dubrovsky B., Gijsbers K., Filipini D.L., Birmingham M.K. Effects of adrenocortical steroids on long term potentiation in the limbic system. Basic mechanisms and behavioral consequences. Cell. Mol. Neurobiol. 13:1993;399-414.
19. Dubrovsky B. Evolution of nervous systems and psychiatry. Consequences of the vertical and horizontal duality of the evolutionary process. J. Psychiatry Neurosci. 18:1993;245-259.
20. Dubrovsky B. Fundamental neuroscience and the classification of psychiatric disorders. Neurosci. Biobehav. Rev. 19:1995;511-518.
21. Dubrovsky B., Yoo A., Harris J. Electrophysiological effects of steroid hormones on nervous systems. Stone T. CNS neurotransmitters and neuromodulators. Neuroactive steroids. 1996;89-102 CRC Press, Boca Raton, FL.
22. Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system. Potential therapeutic benefits. Med. Hypotheses. 49:1997;51-55.
23. ffrench-Mullen J.M.H., Danks P., Spence K. Neurosteroids modulate calcium currents in hippocampal CA1 neurons via a pertussis toxin-sensitive G-protein-coupled mechanism. J. Neurosci. 14:1994;1963-1969.
24. Filipini D., Birmingham M.K., Dubrovsky B. Effects of adrenal steroids and their reduced metabolites on hippocampal long-term potentiation. J. Steroid Biochem. Mol. Biol. 40:1991;87-92.
25. Filipini D., Birmingham M.K., Kraulis I., Dubrovsky B. Modulatory actions of adrenal steroids on limbic structures. J. Steroid Biochem. Mol. Biol. 39:1991;245-252.
26. Fleshner M., Pugh C.R., Tremblay D., Rudy J.W. DHEA-S selectively impairs contextual-fear conditioning; support for the antiglucocorticoid hypothesis. Biobehav. Neurosci. 111:1997;512-517.
27. Flood J.F., Roberts E. Dehydroepiandrosterone sulfate improves memory in aging mice. Brain Res. 448:1988;178-181.
28. Frye A.A., Lacey E.H. The neurosteroids DHEA and DHEAS may influence cognitive performance by altering affective state. Physiol. Behav. 66:1999;85-92.
29. Gold P.W., Goodwin F.K., Chrousos G.P. Clinical and biochemical manifestations of depression Relation to the neurobiology of stress . N. Engl. J. Med. 319:1988;348-353.
30. Harlan-Meyer J., Gruol D.L. Dehydroepiandrosterone sulfate alters synaptic potentials in area CA1 of the hippocampal slice. Brain Res. 633:1994;253-261.
31. Hechter O., Grossman A., Chatterton R.T.J. Relationship of dehydroepiandrosterone and cortisol in disease. Med. Hypotheses. 49:1997;85-91.
32. Herbert J., Goodyear I.M., Altham P.M.E., Pearson J., Secher S.M., Shiers H.M. Adrenal secretion and major depression in 8 to 16 year olds. II. Influence of comorbidity at presenation. Psychol. Med. 26:1996;257-263.
33. Heuser G. Induction of anesthesia, seizures and sleep by steroid hormones. Anesthesiology. 28:1987;173-178.
34. Jeffcoate W.J., Silverstone J.T., Edward C.R., Besser G.M. Psychiatric manifestations of Cushing's syndrome Response to lowering of plasma cortisol . Q. J. Med. 48:1979;465-472.
35. Joels M., de Kloet E.R. Control of neuronal excitability by corticosteroid hormones. Trends Neurosci. 15:1991;25-30.
36. Kaminska M., Harris J., Dubrovsky B. Dehydroepiandrosterone sulfate (DHEAS) counteracts the decremental effects of corticosterone on dentate gyrus LTP. Soc. Neurosci. Abst. 23:1997;418.
37. Karst H., Joels M. The induction of corticosteroid actions on membrane properties of hippocampal CA1 neurons requires protein synthesis. Neurosci. Lett. 130:1991;27-32.
38. 1251 bovine serum albumin as a ligand. J. Neurochem. 54:1990;467-471.
39. Kelly W.F., Checkley S.A., Bender D.A., Mashiter K. Cushing's syndrome and depression A prospective study of 26 patients . Br. J. Psychiatry. 142:1983;16-91.
40. Kramlinger K.G., Peterson G.C., Watson P.K. Metyrapone for depression and delirium secondary to Cushing's syndrome. Psychosomatics. 26:1985;67-71.
41. Kraulis I., Dubrovsky B., Birmingham M. Distribution, metabolism and biological activity of deoxycorticosterone in rat central nervous system. Brain Res. 88:1975;1-14.
42. Krishnan K.R.R. Pituitary and adrenal changes in depression. Psychiatr. Ann. 23:1993;671-675.
43. Landgren S., Backstrom T., Dubrovsky B. The effect of progesterone and its metabolites on the inerictal epileptiform disharge in the cat's cerebral cortex. Acta Physiol. Scand. 131:1987;33-42.
44. Ledoux J.E. search of an emotional system in the brain: Leaping from fear to motion and consciousness. In: Gazzaniga M.S. The cognitive neurosciences. A Bradford book. 1995;1049-1061 The MIT Press, Cambridge, MA.
45. Luine V. Steroid homeone influences on spatial memory. Ann. N.Y. Acad. Sci. 743:1994;201-211.
46. Lupien S.J., Gaudreau S., Tchiteya B.M., Maheau F., Sharma S., Nair N.P., Hauger R.L., McEwen B.S., Meaney M.J. Stress-induced declarative memory impairment in healthy elderly subjects Relationship to cortisol reactivity . J. Clin. Endocrinol. Metab. 82:1997;2070-2075.
47. A receptor. Brain Res. 526:1990;143-146.
48. Majewska M.D. Neurosteroids Endogenous bimodal modulators of the GABA receptor. Mechanisms of action and physiological significance . Prog. Neurobiol. 38:1992;379.
49. Maren S. Sexually dimorphic perforant path long-term potentiation (LTP) in urethane-anesthetized rats. Neurosci. Lett. 196:1995;177-180.
50. Markowitz J.S., Carson W.J., Jackson Ch.W. Possible dehydro-epiandrosterone induced mania. Biol. Psychiatry. 45:1999;241-242.
51. McEwen B.S. Stressful experience, brain and emotions Developmental, genetic and hormonal influences . Gazzaniga M.S. The cognitive neurosciences. A Bradford book. 1995;1117-1136 The MIT Press, Cambridge, MA.
52. Newcomer J.W., Cratt S., Hershey T. Glucocorticoid-induced impairment in declarative memory performance in adult human. J. Neurosci. 14:1994;2047-2053.
53. Newcomer J.W., Selke G., Melson A.K., Hershey T., Craft S., Richards K., Alderson A. Decreased memory performance in healthy humans induced by stress-level cortisol treatment. Arch. Gen. Psychiatry. 56:1999;527-533.
54. Orchinik M., Murray T., Moore F.L. A corticosteroid receptor in neuronal membranes. Science. 152:1991;1848-1851.
55. Pavlides C., Watanabe T., McEwen B.S. Effects of glucocorticoids on hippocampal long-term potentiation. Hippocampus. 3:1993;183-192.
56. Pavlides C., Watanabe Y., Margarinos A.M., McEwen B.S. Opposing rules of type I and type II adrenal steroid receptors in hippocampal long term potentiation. Neuroscience. 68:1995;387-394.
57. Post R.M., Weiss S.R.B., Smith M., Rosen J., Frye M. Stress conditioning and the tempral aspects of affective disorders. Ann. N.Y. Acad. Sci. 771:1995;677-696.
58. Price L.H., Mahson R.T., McDougle C. Antiglucocorticoids as treatments for depression. Rationale for use and therapeutic potentials. CNS Drugs. 5:1996;311-320.
59. Ravaris L.C., Sateira M.J., Beroza K.N., Nordsy D.L., Brinck-Johnsen T. Effect of ketoconazole on a hypophysectomized, hyper-cortisolemic, psychotically depressed woman (letter). Arch. Gen. Psychiatry. 45:1988;966-967.
60. Reddy D.S., Kaur O., Kulkarni S.K. Sigma (σ1) receptor mediated antidepressant-like effects of neurosteroids in the Porsolt forced swim test. NeuroReport. 9:1998;3069-3073.
61. Roberts E. Guides through the labyrinth of AD Dehydroepi-androsterone, potassium channels and the C4 component of complement . Crook T., Bartus R.T., Ferris S., Gershon S. Treatment development strategies for Alzheimer's disease. 1986;173-219 Prowley, Madison, CT.
62. Rubinow D.R., Post R.M., Savard R., Gold P.W. Cortisol hyper-secretion and cognitive impairment in depression. Arch. Gen. Psychiatry. 41:1984;279-383.
63. Scharfman H., Sarvey J.M. Postsynaptic firing during repetitive stimulation is required for long term potentiation in hippocampus. Brain Res. 331:1985;267-274.
64. Shirasaka Y., Wasterlain C.G. The effects of urethane anesthesia on evoked potentials in dentate gyrus. Eur. J. Pharmacol. 282:1995;11-17.
65. Silberman E.K., Weingartner H., Targum S.D., Byrnes S. Cognitive functioning in biological subtypes of depression. Biol. Psychiatry. 20:1985;654-661.
66. Squire L.S., Kandel E.R. Memory From molecules to memory. Scientific American Library . 1999;Freeman Press, New York.
67. Starkman N.M., Schteingart D.E., Schorck M.A. Depressed mood and other psychiatric manifestations of Cushing's syndrome relationship to hormone levels. Psychosomat. Med. 43:1981;3-18.
68. Starkman N.M., Schteingart D.E., Schorck M.A. Cushing's syndrome after treatment. Changes in cortisol and ACTH levels and amelioration of the depressive syndrome. Psychiatric Res. 19:1986;177-188.
69. Urbanoski, K.; Harris, J.; Dubrovsky, B. Androsterone sulfate enhances population spike in the hippocampus after tetanic stimulation of perforant path. Physiol. Behav. In press.
70. Weiss N.A., Hassett M.J. Introductory statistics. 1991;Addison-Wesley, New York.
71. Wolkowitz O.M., Heus V.I., Weingartner H., Thompson K., Breier A., Doran A., Rubinow D., Picar D. Cognitive effects of corticosteroids. Am. J. Psychiatry. 147:1990;1297-1303.
72. Wolkowitz O.M., Reus M.D., Keebler A., Nelson N., Friedland M., Brizendine M.D., Roberts E. Double blind treatment of major depression with dehydroepiandrostrone. Am. J. Psychiatry. 156:1999;646-649.
73. Yoo A., Harris J., Dubrovsky B. Dose response study of dehydroepiandrosterone sulfate on dentate gyrus LTP. Exp. Neurol. 137:1996;151-156.
74. Young E.A. DHEA Mood, memory and aging . Biol. Psychiatry. 45:1999;1531-1532.