GluR4c, an alternative splicing isoform of GluR4, is abundantly expressed in the adult human brain

Molecular Brain Research

Volumn 127, Issue 1-2, 2004, Pages 150-155

  Kawahara, Yukio ^a   Ito, Kyoko ^a   Sun, Hui ^a   Ito, Masayuki ^b   Kanazawa, Ichiro ^a,c   Kwak, Shin ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Alternative splicing; AMPA receptor; Excitatory amino acid receptors: structure, function and expression; GluR subunit; Neurotransmitters, modulators, transporters, and receptors; PDZ domain; Quantitative RT PCR

Indexed keywords

AMPA RECEPTOR; GLUTAMATE RECEPTOR 4; GLUTAMATE RECEPTOR 4C; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRAIN; BRAIN CORTEX; CARBOXY TERMINAL SEQUENCE; CEREBELLUM; CHICKEN; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; FETUS; GENE CONTROL; HUMAN; HUMAN TISSUE; INFANT; MALE; MOLECULAR CLONING; NEWBORN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RODENT; STOP CODON; UPREGULATION;

ADULT; AGED; ALTERNATIVE SPLICING; ANIMALS; BRAIN; CHICKENS; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IN SITU HYBRIDIZATION; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; POSTMORTEM CHANGES; PROTEIN ISOFORMS; RATS; RECEPTORS, AMPA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA;

RODENTIA;

EID: 4043112668     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2004.05.020     Document Type: Article

References (28)

1. Carvalho A.L., Kameyama K., Huganir R.L. Characterization of phosphorylation sites on the glutamate receptor 4 subunit of the AMPA receptors. J. Neurosci. 19:1999;4748-4754
2. Dev K.K., Nishimune A., Henley J.M., Nakanishi S. The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits. Neuropharmacology. 38:1999;635-644
3. Esteban J.A., Shi S.H., Wilson C., Nuriya M., Huganir R.L., Malinow R. PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nat. Neurosci. 6:2003;136-143
4. Gallo V., Upson L.M., Hayes W.P., Vyklicky L. Jr., Winters C.A., Buonanno A. Molecular cloning and development analysis of a new glutamate receptor subunit isoform in cerebellum. J. Neurosci. 12:1992;1010-1023
5. Hayashi Y., Shi S.H., Esteban J.A., Piccini A., Poncer J.C., Malinow R. Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science. 287:2000;2262-2267
6. Jakowec M.W., Yen L., Kalb R.G. In situ hybridization analysis of AMPA receptor subunit gene expression in the developing rat spinal cord. Neuroscience. 67:1995;909-920
7. Jespersen L.K., Kuusinen A., Orellana A., Keinänen K., Engberg J. Use of proteoliposomes to generate phage antibodies against native AMPA receptor. Eur. J. Biochem. 267:2000;1382-1389
8. Kawahara Y., Ito K., Sun H., Kanazawa I., Kwak S. Low editing efficiency of GluR2 mRNA is associated with a low relative abundance of ADAR2 mRNA in white matter of normal human brain. Eur. J. Neurosci. 18:2003;23-33
9. Kawahara Y., Ito K., Sun H., Ito M., Kanazawa I., Kwak S. Regulation of glutamate receptor RNA editing and ADAR mRNA expression in developing human normal and Down's syndrome brains. Dev. Brain Res. 148:2004;151-155
10. Keinänen K., Wisden W., Sommer B., Werner P., Herb A., Verdoorn T.A., Sakmann B., Seeburg P.H. A family of AMPA-selective glutamate receptors. Science. 249:1990;556-560
11. Köhler M., Kornau H.C., Seeburg P.H. The organization of the gene for the functionally dominant alpha-amino-3-hydroxy-5-methylisoxazole-4- propionic acid receptor subunit GluR-B. J. Biol. Chem. 269:1994;17367-17370
12. Kolleker A., Zhu J.J., Schupp B.J., Qin Y., Mack V., Borchardt T., Kohr G., Malinow R., Seeburg P.H., Osten P. Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors. Neuron. 40:2003;1199-1212
13. Leonard A.S., Davare M.A., Horne M.C., Garner C.C., Hell J.W. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit. J. Biol. Chem. 273:1998;19518-19524
14. Malinow R., Malenka R.C. AMPA receptor trafficking and synaptic plasticity. Annu. Rev. Neurosci. 25:2002;103-126
15. Monyer H., Seeburg P.H., Wisden W. Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing. Neuron. 6:1991;799-810
16. Mosbacher J., Schoepfer R., Monyer H., Burnashev N., Seeburg P.H., Ruppersberg J.P. A molecular determinant for submillisecond desensitization in glutamate receptors. Science. 266:1994;1059-1062
17. Page K.J., Everitt B.J. The distribution of neurons coexpressing immunoreactivity to AMPA-sensitive glutamate receptor subtypes (GluR1-4) and nerve growth factor receptor in the rat basal forebrain. Eur. J. Neurosci. 7:1995;1022-1033
18. Page K.J., Everitt B.J., Robbins T.W., Marston H.M., Wilkinson L.S. Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: differential dependence on cholinergic neuronal loss. Neuroscience. 43:1991;457-472
19. Puchalski R., Louis J., Brose N., Traynelis S., Egebjerg J., Kukekov V., Wenthold R., Rogers S., Lin F., Moran T., Morrison J.N., Heinemann S.F. Selective RNA editing and subunit assembly of native glutamate receptors. Neuron. 13:1994;131-147
20. Ravindranathan A., Parks T.N., Rao M.S. New isoforms of the chick glutamate receptor subunit GluR4: molecular cloning, regional expression and developmental analysis. Mol. Brain Res. 50:1997;143-153
21. Shi S., Hayashi Y., Esteban J.A., Malinow R. Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell. 105:2001;331-343
22. Siegel S.J., Janssen W.G., Tullai J.W., Rogers S.W., Moran T., Heinemann S.F., Morrison J.H. Distribution of the excitatory amino acid receptor subunits GluR2(4) in monkey hippocampus and colocalization with subunits GluR5-7 and NMDAR1. J. Neurosci. 15:1995;2707-2719
23. Song I., Huganir R.L. Regulation of AMPA receptors during synaptic plasticity. Trends Neurosci. 25:2002;578-588
24. Tomiyama M., Rodriguez-Puertas R., Cortes R., Christnacher A., Sommer B., Pazos A., Palacios J., Mengod G. Differential regional distribution of AMPA receptor subunit messenger RNAs in the human spinal cord as visualized by in situ hybridization. Neuroscience. 75:1996;901-915
25. Tomiyama M., Palacios J.M., Cortes R., Mengod G. Flip and flop variants of AMPA receptor subunits in the human cerebellum: implication for the selective vulnerability of Purkinje cells. Synapse. 31:1999;163-167
26. Tölle T.R., Berthele A., Zieglgänsberger W., Seeburg P.H., Wisden W. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. J. Neurosci. 13:1993;5009-5028
27. Wenthold R.J., Petralia R.S., Blahos J. II, Niedzielski A.S. Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons. J. Neurosci. 16:1996;1982-1989
28. Zhu J.J., Esteban J.A., Hayashi Y., Malinow R. Postnatal synaptic potentiation: delivery of GluR4-containing AMPA receptors by spontaneous activity. Nat. Neurosci. 3:2000;1098-1106