DNA-functionalized nanotube, membranes with single-base mismatch selectivity

Science

Volumn 305, Issue 5686, 2004, Pages 984-986

  Kohli, Punit ^a   Harrell, C Chad ^a   Cao, Zehui ^a   Gasparac, Raheta ^a   Tan, Weihong ^a   Martin, Charles R ^a  

^a University of Florida ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GOLD; PERMSELECTIVE MEMBRANES;

MOLECULAR RECOGNITIONS; SELECTIVE PERMEATION;

NANOTUBES;

NANOTUBE;

BIOLOGY; DNA;

ARTICLE; BASE MISPAIRING; DNA HYBRIDIZATION; DNA STRAND; DNA STRUCTURE; DNA TRANSFER; MEMBRANE; MEMBRANE TRANSPORT; MOLECULAR RECOGNITION; PRIORITY JOURNAL;

BASE PAIR MISMATCH; BIOLOGICAL TRANSPORT; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; GOLD; MEMBRANES, ARTIFICIAL; NANOTUBES; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION;

EID: 4043104957     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1100024     Document Type: Article

References (19)

1. D. A. Doyle et al., Science 280, 69 (1998).
2. J. Abramson et al., Science 301, 610 (2003).
3. B. Hille, Ion Channels of Excitable Membranes (Sinauer, Sunderland, MA, ed. 3, 2001), pp. 441-470.
4. S. B. Lee et al., Science 296, 2198 (2002).
5. B. B. Lakshmi, C. R. Martin, Nature 388, 758 (1997).
6. An interesting example of attaching a single-stranded DNA molecule to a protein channel to make a new type of DNA sensor has been reported (18).
7. H. Fried, U. Kutay, Cell. Mol. Life Sci. 60, 1659 (2003).
8. G. Bonnet, S. Tyagi, A. Libchaber, F. R. Kramer, Proc. Natl. Acad. Sci. U.S.A. 96, 6171 (1999).
9. B. Dubertret, M. Calame, A. J. Libchaber, Nature Biotechnol. 19, 365 (2001).
10. C. R. Martin, M. Nishizawa, K. Jirage, M. Kang, J. Phys. Chem. B 105, 1925 (2001).
11. K. B. Jirage, J. C. Hulteen, C. R. Martin, Science 278, 655 (1997).
12. C. R. Martin, Science 266, 1961 (1994).
13. Materials and methods are available as supporting material art Science Online.
14. M. Mulder, Basic Principles of Membrane Technology (Kluwer, Dordrecht, Netherlands, 1996), pp. 342-351.
15. Y. Osada, T. Nakagawa, in Membrane Science and Technology, Y. Osada, T. Nakagawa, Eds. (Marcel Dekker, New York, 1992), pp. 377-391.
16. A fluorescence-based method was used to provide direct evidence for clipping of the double-stranded DNA by the restriction enzyme (13).
17. M. C. Hall, H. Wang, D. A. Erie, T. A. Kunkel, J. Mol. Biol. 312, 637 (2001).
18. S. Howorka, S. Cheley, H. Bayley, Nature Biotech. 19, 636 (2001).
19. Supported by the National Science Foundation and by the Defense Advanced Research Projects Agency.