The role of cyclooxygenases and prostanoid receptors in furosemide-like salt losing tubulopathy: The hyperprostaglandin E syndrome

Acta Physiologica Scandinavica

Volumn 181, Issue 4, 2004, Pages 523-528

  Nusing R M ^a   Seyberth, H W ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Cyclooxygenase; Electrolyte; Kidney; Prostaglandin; Receptor; Tubulopathy

Indexed keywords

ALDOSTERONE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; POTASSIUM CHANNEL; PROSTAGLANDIN E2; PROSTANOID; PROSTANOID RECEPTOR; RENIN; SODIUM POTASSIUM CHLORIDE COTRANSPORTER;

ALDOSTERONE BLOOD LEVEL; CLINICAL FEATURE; CONFERENCE PAPER; DIURESIS; GENE MUTATION; HUMAN; HYPERALDOSTERONISM; HYPERPROSTAGLANDIN E SYNDROME; HYPERRENINEMIA; ION TRANSPORT; KIDNEY HYPERTROPHY; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE DISORDER; MALABSORPTION; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROSTAGLANDIN URINE LEVEL; SODIUM DEPLETION; TRANSPORT KINETICS;

BARTTER SYNDROME; DIURESIS; HUMANS; KIDNEY; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS E; RECEPTORS, PROSTAGLANDIN E;

EID: 4043089217     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-201X.2004.01326.x     Document Type: Conference Paper

References (41)

1. Bartter, F.C., Pronove, P., Gill, J.R. & MacCardle, R.C. 1962. Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis: a new syndrome. Am J Med 33, 811-828.
2. Fernandez-Llama, P., Ecelbarger, C.A., Ware, J.A. et al. 1999. Cyclooxygenase inhibitors increase Na-K-2Cl cotransporter abundance in thick ascending limb of Henle's loop. Am J Physiol 277, F219-F226.
3. Harding, P., Sigmon, D.H., Alfie, M.E. et al. 1997. Cyclooxygenase-2 mediates increased renal renin content induced by low-sodium diet. Hypertension 29, 297-302.
4. Harris, R.C., McKanna, J.A., Akai, Y., Jacobson, H.R., Dubois, R.N. & Breyer, M.D. 1994. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest 94, 2504-2510.
5. Imig, J.D., Breyer, M.D. & Breyer, R.M. 2002. Contribution of prostaglandin EP(2) receptors to renal microvascular reactivity in mice. Am J Physiol Renal Physiol 283, F415-F422.
6. Jensen, B.L., Stubbe, J., Hansen, P.E., Andreasen, D. & Skott, O. 2001. Localization of prostaglandin E(2) EP2 and EP4 receptors in the rat kidney. Am J Physiol Renal Physiol 280, F1001-F1009.
7. Kaji, D.M., Chase, H.S., Eng, J.P. & Diaz, J. 1996. Prostaglandin E(2) inhibits Na-K-2Cl cotransport in medullary thick ascending limb cells. Am J Physiol 271, C354-C361.
8. Kammerl, M.C., Nüsing, R.M., Richthammer, W., Kramer, B.K. & Kurtz, A. 2001. Inhibition of COX-2 counteracts the effects of diuretics in rats. Kidney Int 60, 1684-1691.
9. Karolyi, L., Konrad, M., Köckerling, A. et al. 1997. Mutations in the gene encoding the inwardly-rectifying renal potassium channel, ROMK, cause the antenatal variant of Bartter syndrome: evidence for genetic heterogeneity. Hum Mol Genet 6, 17-26.
10. Kennedy, C.R., Zhang, Y., Brandon, S. et al. 1999. Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor. Nat Med 5, 217-220.
11. Kirchner, K.A. 1985. Prostaglandin inhibitors alter loop segment chloride uptake during furosemide diuresis. Am J Physiol 248, F698-F704.
12. Kobayashi, T. & Narumiya, S. 2002. Function of prostanoid receptors: studies on knockout mice. Prostaglandins Other Lipid Mediat 68-69, 557-573.
13. Kömhoff, M., Gröne, H.J., Klein, T., Seyberth, H.W. & Nüsing, R.M. 1997. Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: implication for renal function. Am J Physiol 272, F460-F468.
14. Kömhoff, M., Jeck, N.D., Seyberth, H.W., Gröne, H.J., Nüsing, R.M. & Breyer, M.D. 2000. Cyclooxygenase-2 expression is associated with the renal macula densa of patients with bartter-like syndrome. Kidney Int 58, 2420-2424.
15. Kömhoff, M., Reinalter, S.C., Grone, H.J. & Seyberth, H.W. 2003. Induction of microsomal prostaglandin E2 synthase in the macula densa in children with hypokalemic salt-losing tubulopathies. Pediatr Res 19, 19.
16. Konrad, M., Leonhardt, A., Hensen, P., Seyberth, H.W. & Köckerling, A. 1999. Prenatal and postnatal management of hyperprostaglandin E syndrome after genetic diagnosis from amniocytes. Pediatrics 103, 678-683.
17. Lane, P.H. 1995. Furosemide treatment, angiotensin II, and renal growth and development in the rat. Pediatr Res 37, 747-754.
18. Lane, P.H. 1999. Long-term furosemide treatment in the normal rat: dissociation of glomerular hypertrophy and glomerulosclerosis. Am J Kidney Dis 33, 1058-1063.
19. Liu, H.J., Wei, Y., Ferreri, N.R., Nasjletti, A., Wang, W.H. & Fererri, N.R. 2000. Vasopressin and PGE(2) regulate activity of apical 70 pS K(+) channel in thick ascending limb of rat kidney. Am J Physiol Cell Physiol 278, C905-C913.
20. Lorenz, J.N., Baird, N.R., Judd, L.M. et al. 2002. Impaired renal NaCl absorption in mice lacking the ROMK potassium channel, a model for type II Bartter's syndrome. J Biol Chem 16, 16.
21. Lu, M., Wang, T., Yan, Q. et al. 2002. Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. J Biol Chem 277, 37881-37887.
22. Morath, R., Klein, T., Seyberth, H.W. & Nüsing, R.M. 1999. Immunolocalization of the four prostaglandin E2 receptor proteins EP1, EP2, EP3, and EP4 in human kidney. J Am Soc Nephrol 10, 1851-1860.
23. Narumiya, S., Sugimoto, Y. & Ushikubi, F. 1999. Prostanoid receptors: structures, properties, and functions. Physiol Rev 79, 1193-1226.
24. Nüsing, R.M., Reinalter, S. & Seyberth, H.W. 1999. Use of nimesulide, a cyclooxygenase-2 inhibitor, for treatment of hyperprostaglandin E syndrome. Eur J Clin Pharmacol 55, A10.
25. Peters, M., Jeck, N., Reinalter, S. et al. 2002. Clinical presentation of genetically defined patients with hypokalemic salt-losing tubulopathies. Am J Med 112, 183-190.
26. Reinalter, S.C., Grone, H.J., Konrad, M., Seyberth, H.W. & Klaus, G. 2001. Evaluation of long-term treatment with indomethacin in hereditary hypokalemic salt-losing tubulopathies. J Pediatr 139, 398-406.
27. Reinalter, S.C., Jeck, N., Brochhausen, C. et al. 2002. Role of cyclooxygenase-2 in hyperprostaglandin E syndrome/antenatal Bartter syndrome. Kidney Int 62, 253-260.
28. Schnermann, J. 1998. Juxtaglomerular cell complex in the regulation of renal salt excretion. Am J Physiol 274, R263-R279.
29. Seidel, C., Reinalter, S., Seyberth, H.W. & Schärer, K. 1995. Pre-pubertal growth in the hyperprostaglandin E syndrome. Pediatr Nephrol 9, 723-728.
30. Seyberth, H.W., Rascher, W., Schweer, H., Kühl, P.G., Mehls, O. & Schärer, K. 1985. Congenital hypokalemia with hypercalciuria in preterm infants: a hyperprostaglandinuric tubular syndrome different from Bartter syndrome. J Pediatr 107, 694-701.
31. Seyberth, H.W., Königer, S.J., Rascher, W., Kühl, P.G. & Schweer, H. 1987. Role of prostaglandins in hyperprostaglandine E syndrome and in selected renal tubular disorders. Pediatr Nephrol 1, 491-497.
32. Seyberth, H.W., Soergel, M. & Köckerling, A. 1998. Hypokalaemic tubular disorders: the hyperprostaglandin E syndrome and the Gitelman-Bartter syndrome. In: A.M. Davison, J.S. Cameron, J.-P. Grünfeld, D.N.S. Kerr & E. Ritz (eds) Oxford Textbook of Clinical Nephrology, pp. 1085-1094. Oxford University Press, Oxford.
33. Simon, D.B., Karet, F.E., Hamdan, J.M., Dipietro, A., Sanjad, S.A. & Lifton, R.P. 1996a. Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2. Nat Genet 13, 183-188.
34. Simon, D.B., Karet, F.E., Rodriguezsoriano, J. et al. 1996b. Genetic heterogeneity of Bartter's syndrome revealed by mutations in the K+ channel, ROMK. Nat Genet 14, 152-156.
35. Sugimoto, Y., Namba, T., Shigemoto, R., Negishi, M., Ichikawa, A. & Narumiya, S. 1994. Distinct cellular localization of mRNAs for three subtypes of prostaglandin E receptor in kidney. Am J Physiol 266, F823-F828.
36. Takahashi, N., Chernavvsky, D.R., Gomez, R.A., Igarashi, P., Gitelman, H.J. & Smithies, O. 2000. Uncompensated polyuria in a mouse model of Bartter's syndrome. Proc Natl Acad Sci USA 97, 5434-5439.
37. Tang, L., Loutzenhiser, K. & Loutzenhiser, R. 2000. Biphasic actions of prostaglandin E(2) on the renal afferent arteriole: role of EP(3) and EP(4) receptors. Circ Res 86, 663-670.
38. Taugner, R., Waldherr, R., Seyberth, H.W., Erdos, E.G., Menard, J. & Schneider, D. 1988. The juxtaglomerular apparatus in Bartter's syndrome and related tubulopathies. An immunocytochemical and electron microscopic study. Virchows Arch A Pathol Anat Histopathol 412, 459-470.
39. Vane, J.R., Bakhle, Y.S. & Botting, R.M. 1998. Cyclooxygenases 1 and 2. Annu Rev Pharmacol Toxicol 38, 97-120.
40. Wang, J.L., Cheng, H.F. & Harris, R.C. 1999. Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension. Hypertension 34, 96-101.
41. Wilson, D.R., Honrath, U. & Sonnenberg, H. 1983. Furosemide action on collecting ducts: effect of prostaglandin synthesis inhibition. Am J Physiol 244, F666-F673.