Inhibition of COX-2 counteracts the effects of diuretics in rats

Kidney International

Volumn 60, Issue 5, 2001, Pages 1684-1691

  Kammerl, Martin C ^a,b   Nüsing, Rolf M ^a,b   Richthammer, Wolfgang ^a,b   Krämer, Bernhard K ^a,b   Kurtz, Armin ^a,b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Bartter disease; Furosemide; Gitelman disease; Hydrochlorothiazide; Loop diuretics; Prostaglandins; Renin system; Salt and water wasting; Saluresis; Urinary excretion

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DIURETIC AGENT; FUROSEMIDE; HYDROCHLOROTHIAZIDE; MESSENGER RNA; PROSTANOID; ROFECOXIB;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIURESIS; DOSE RESPONSE; ENZYME INDUCTION; ENZYME INHIBITION; KIDNEY DISTAL TUBULE; MALE; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SALT LOSING NEPHRITIS; SALURESIS; URINARY EXCRETION;

EID: 0034779539     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.00988.x     Document Type: Article

References (31)

1. Renal vascular and excretory responses to prostaglandin endoperoxides in the dog
2. Prostaglandins stimulate renin secretion and renin mRNA in mouse renal juxtaglomerular cells
3. Effects of nonsteroidal anti-inflammatory drugs (NSAID) on renal excretion of sodium and water, and on body fluid volume in rats
4. Suppression of plasma renin activity by indomethacin in man
5. Nitric oxide and prostaglandins are involved in the macula densa control of the renin system
6. Prostaglandins are overproduced by the kidneys and mediate hyperreninemia in Bartter's syndrome
7. Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: Implication for renal function
8. Interspecies differences in renal localization of cyclooxygenase isoforms: Implications in nonsteroidal antiinflammatory drug-related nephrotoxicity
9. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
10. Regulation of cyclooxygenase expression in the kidney by dietary salt intake
11. Effect of selective inhibition of the inducible cyclooxygenase on renin release in healthy volunteers
12. Low chloride stimulation of prostaglandin E2 release and cyclooxygenase-2 expression in a mouse macula densa cell line
13. Inhibition of macula densa-stimulated renin secretion by pharmacological blockade of cyclooxygenase-2
14. Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension
15. Chronic cyclooxygenase-2 inhibition blunts low sodium-stimulated renin without changing renal haemodynamics
16. Furosemide stimulates macula densa cyclooxygenase-2 expression in rats
17. Cyclooxygenase-2 expression is associated with the renal macula densa of patients with Bartter-like syndrome
18. NaCl transport deficiencies: Hemodynamics to the rescue
19. Thiazide-sensitive sodium chloride cotransport in early distal tubule
20. Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor: Pharmacological and biochemical profiles
21. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
22. Differential regulation of renal cyclooxygenase mRNA by dietary salt intake
23. Differential effects of kinase inhibitors on erythropoietin and vascular endothelial growth factor gene expression in rat hepatocytes
24. Determination of seven prostanoids in 1 ml of urine by gas chromatography-negative ion chemical ionization triple stage quadruple mass spectrometry
25. Cyclooxygenase-2 in rat nephron development
26. Inhibition of the renin-angiotensin system upregulates cyclooxygenase-2 expression in the macula densa
27. Role of p38 in the regulation of renal cortical cyclooxygenase-2 expression by extracellular chloride
28. Microinjection studies on the effect of furosemide on the rat nephron
29. Effects of alterations in urine flow rate on prostaglandin E excretion in conscious dogs
30. Cyclooxygenase inhibitors increase Na-K-2Cl cotransporter abundance in thick ascending limb of Henle's loop
31. Body fluid homeostasis in man: A contemporary overview