The presynaptic activity of bothropstoxin-I, a myotoxin from Bothrops jararacussu snake venom

Basic and Clinical Pharmacology and Toxicology

Volumn 95, Issue 4, 2004, Pages 175-182

  Oshima Franco, Yoko ^a   Leite, Gildo Bernardo ^a   Dal Belo, Cháriston André ^a   Hyslop, Stephen ^a   Prado Franceschi, Júlia ^a   Cintra, Adélia Cristina Oliveira ^b   Giglio, José Roberto ^b   Da Cruz Höfling, Maria Alice ^a   Rodrigues Simioni, Léa ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BOTHROPSTOXIN I; LYSINE; MANGANESE; PHOSPHOLIPASE A2; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BOTHROPS JARARACUSSU; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DRUG ACTIVITY; DRUG MECHANISM; ELECTROPHYSIOLOGY; ENDPLATE POTENTIAL; MALE; MEMBRANE STEADY POTENTIAL; MINIATURE ENDPLATE POTENTIAL; MOUSE; MUSCLE TWITCH; NEUROMUSCULAR BLOCKING; NEUROTOXICITY; NONHUMAN; PHRENIC NERVE; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SNAKE;

ANIMALIA; BOTHROPS; BOTHROPS JARARACUSSU; SERPENTES;

EID: 4043082217     PISSN: 17427835     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2004.pto_950405.x     Document Type: Article

References (42)

1. Balnave, R. J. & P. W. Gage: The inhibitory effect of manganese on transmitter release at the neuromuscular junction of the toad. Brit. J. Pharmacol. 1973, 47, 339-352.
2. Bülbring, E.: Observation on the isolated phrenic nerve diaphragm preparation of the rat. Brit. J. Pharmacol. 1946, 1, 38-61.
3. Campbell, J. A. & W. W. Lamar: The venomous reptiles of Latin America. Comstock Publishing Associates/Cornell University Press, Ithaca, NY, 1989.
4. Chang, C. C., S. T. Chang, C. Y. Lee & J. W. Wei: Role of cardiotoxin and phospholipase A in the blockade of nerve conduction and depolarization of skeletal muscle induced by cobra venom. Brit. J. Pharmacol. 1972, 44, 752-764.
5. Cintra, A. C. O., S. Marangoni, B. Oliveira & J. R. Giglio: Bothropstoxin-I: amino acid sequence and function. J. Protein Chem. 1993, 12, 57-64.
6. Dal Belo, C. A., G. B. Leite, M. D. Fontana, A. P. Corrado, A. C. Z. Baso, C. S. N. Moreno-Serra, A. C. Oliveira & L. Rodrigues-Simioni: New evidence for a presynaptic action of prednisolone at neuromuscular junctions. Muscle Nerve 2002, 26, 37-43.
7. 2, anticoagulant and myotoxic activities. Biochim. Biophys. Acta 1991, 1070, 455-60.
8. Earl, J. E. & B. J. Excell: The action of a depolarizing fraction from Naja nivea venom on frog skeletal muscle. J. Physiol. 1971, 214, 27-28.
9. Elmqvist, D. & D. M. J. Quastel: A quantitative study of end-plate potentials in isolated human muscle. J. Physiol. 1965, 178, 505-529.
10. Fatt, P. & B. Katz: Analysis of the end-plate potential with an intracellular electrode. J. Physiol. 1951, 115, 320-370.
11. Fatt, P. & B. Katz: Spontaneous subthreshold activity at motor nerve endings. J. Physiol. 1952, 117, 109-128.
12. 2 from Naja nigricollis snake venom: phospholipid hydrolysis and effects on electrical and contractile activity of the rat heart. Toxicol. Appl. Pharmacol. 1982, 66, 39-54.
13. Getz, D., J. F. Gibson, R. N. Sheppard, K. J. Micklem & C. A. Pasternak: Manganese as a calcium probe: electron paramagnetic resonance and nuclear magnetic resonance spectroscopy of intact cells. J. Memb. Biol. 1979, 50, 311-329.
14. 2 myotoxins from Bothrops snake venoms. Toxicon 1995, 33, 1405-1424.
15. Heluany, N. F., M. I. Homsi-Brandeburgo, J. R. Giglio, J. Prado-Franceschi & L. Rodrigues-Simioni: Effects induced by bothropstoxin, a component from Bothrops jararacussu snake venom, on mouse and chick muscle preparations. Toxicon 1992, 30, 1203-1210.
16. Homsi-Brandeburgo, M. I., L. S. Queiroz, H. Santo-Neto, L. Rodrigues-Simioni & J. R. Giglio: Fractionation of Bothrops jararacussu snake venom: partial chemical characterization and biological activity of bothropstoxin. Toxicon 1988, 26, 615-627.
17. Impraim, C. C., K. J. Micklem & C. A. Pasternak: Calcium, cells and virus: alterations caused by paramyxoviruses. Biochem. Pharmacol 1979, 28, 1963-1969.
18. Kriebel, M. E., J. Vautrin & J. Holsapple: Transmitter release: pre-packaging and random mechanism or dynamic and deterministic process. Brain Res. Rev. 1990, 15, 167-178.
19. Lewis, B. A., J.-M. Freyssinet & J. J. Holbrook: An equilibrium study of metal ion binding to human plasma coagulation factor XIII. Biochem. J. 1978, 169, 397-402.
20. 2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-49. Biochemistry 1994, 33, 14714-14722.
21. Lin Shiau, S. Y., N. C. Huang & C. Y. Lee: Mechanism of action of cobra cardiotoxin in the skeletal muscle. J. Pharmacol. Exp. Therap. 1976, 196, 758-770.
22. Ling, G. & R. W. Gerard: The normal membrane potential of frog sartorius fibres. J. Cell Physiol. 1949, 34, 383-396.
23. 2 from the venom of Agkistrodon piscivorus piscivorus. J. Biol. Chem. 1986, 261, 4797-4804.
24. Martin, A. R.: A further study of the statistical composition of the end-plate potential. J. Physiol. 1955, 130, 114-122.
25. Meiri, U. & R. Rahamimoff: Neuromuscular transmission: inhibition by manganese ions. Science 1972, 176, 308-309.
26. ++ accumulation in mitochondria. Biochemistry 1968, 7, 4059-4063.
27. Melo, P. A., M. I. Homsi-Brandeburgo, J. R. Giglio & G. Suarez-Kurtz: Antagonism of the myotoxic effects of Bothrops jararacussu venom and bothropstoxin by polyanions. Toxicon 1993, 31, 285-291.
28. Milani Jr., R., M. T. Jorge, F. P. de Campos, F. P. Martins, A. Bousso, J. L. Cardoso, L. A. Ribeiro, H. W. Fan, F. O. França, I. S. Sano-Martins, D. Cardoso, C. Ide Fernandez, J. C. Fernandes, V. L. Aldred, M. P. Sandoval, G. Puorto, R. D. Theakston & D. A. Warrell: Snake bites by the jararacuçu (Bothrops jararacussu): clinicopathological studies of 29 proven cases in São Paulo State, Brazil. Q. J. Med. 1997, 90, 323-334.
29. Mildvan, A. S. & M. Cohn: Aspects of enzyme mechanisms studied by nuclear spin relaxation induced by paramagnetic probes. Adv. Enzymol. 1970, 33, 1-70.
30. Miyamoto, M.: Binomial analysis of quantal transmitter release at glycerol treated frog neuromuscular junction. J. Physiol. 1975, 250, 121-142.
31. Nachshen, D. A.: Selectivity of the Ca binding site in synaptosome Ca channels: inhibition of Ca influx by multivalent metal cations. J. Gen. Physiol. 1984, 83, 941-967.
32. Oshima-Franco, Y., S. Hyslop, A. C. O. Cintra, J. R. Giglio, M. A. Cruz-Höfling & L. Rodrigues-Simioni: Neutralizing capacity of commercial bothropic antivenom against Bothrops jararacussu venom and bothropstoxin-I. Muscle Nerve 2000, 23, 1832-1839.
33. Oshima-Franco, Y., G. B. Leite, G. H. Silva, D.F. Cardoso, S. Hyslop, J. R. Giglio, M. A. Cruz-Höfling & L. Rodrigues-Simioni: Neutralization of the pharmacological effects of bothropstoxin-I from Bothrops jararacussu (jararacuçu) venom by crotoxin anti-serum and heparin. Toxicon 2001, 39, 1477-1485.
34. 2 proteins. Toxicon 1999, 37, 411-445.
35. Rasgado-Flores, H., S. Sanches-Armass, M. P. Blaustein, & D. A. Nachshen: Strontium, barium, and manganese metabolism in isolated presynaptic nerve terminals. Amer. J. Physiol. 1987, 252, C604-C610.
36. Rodrigues-Simioni, L., N. Borgese & B. Ceccarelli: The effects of Bothrops jararacussu venom and its components on frog nerve-muscle preparation. Neuroscience 1983, 10, 475-489.
37. 2 myotoxin. Toxicon 1995, 33, 1479-1489.
38. Rufini, S., P. Cesaroni, A. Desideri, R. Farias, F. Gubensek, J. M. Gutiérrez, R. Uly, R. Massoud, R. Moreno & J. Z. Pederson: Calcium ion independent membrane leakage induced by phospholipase-like myotoxins. Biochemistry 1992, 31, 12424-12430.
39. Sellin, L. C., J. Molgó, K. Törnquist, B. Hansson & S. Thesleff: On the possible origin of "giant or slow-rising" miniature end-plate potentials at the neuromuscular junction. Eur. J. Physiol. 1996, 431, 325-334.
40. 2 homologue from Bothrops jararacussu snake venom. Int. J. Biochem. Cell Biol. 2002, 34, 668-677.
41. Toister, A. & A. Loyter: The mechanism of cell fusion. II. Formation of chicken erythrocyte polykaryons. J. Biol. Chem. 1973, 248, 422-432.
42. 2 from Agkistrodon piscivorus piscivorus venom. Eur. J. Biochem. 1988, 176, 353-357.