Neutralization of the pharmacological effects of bothropstoxin-I from Bothrops jararacussu (jararacuçu) venom by crotoxin antiserum and heparin

Toxicon

Volumn 39, Issue 10, 2001, Pages 1477-1485

  Oshima Franco, Yoko ^a   Leite, Gildo B ^a   Silva, Gustavo H ^a   Cardoso, Diva F ^b   Hyslop, Stephen ^a   Giglio, José R ^c   Da Cruz Höfling, Maria Alice ^a   Rodrigues Simioni, Lea ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antiserum; Bothropstoxin I; Crotoxin; Myotoxicity; Neurotoxicity

Indexed keywords

BOTHROSTOXIN 1; CROTOXIN; HEPARIN; SNAKE VENOM; SNAKE VENOM ANTISERUM; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; INCUBATION TIME; MALE; MICROSCOPY; MOUSE; NERVE STIMULATION; NEUROMUSCULAR BLOCKING; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL;

ANIMALS; ANTIVENINS; BOTHROPS; CROTALID VENOMS; CROTOXIN; ELECTRIC STIMULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEPARIN; IMMUNOGLOBULIN G; INJECTIONS, SUBCUTANEOUS; MALE; MICE; MUSCLE, SKELETAL; NEUROMUSCULAR BLOCKADE; NEUROMUSCULAR JUNCTION; NEUTRALIZATION TESTS; PHRENIC NERVE; RABBITS; TIME FACTORS;

BOTHROPS JARARACUSSU;

EID: 0034898670     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(01)00107-6     Document Type: Article

References (37)

1. Binding of the asymmetric forms of acetylcholinesterase to heparin
2. Anchorage of collagen-tailed acetylcholinesterase to the extracellular matrix is mediated by heparan sulfate proteoglycans
3. Contribuição ao estudo do veneno ophidico. III. Tratamento das mordeduras de cobras
4. Nova contribuição ao estudo do envenenamento ophidico
5. Observations on the isolated phrenic nerve-diaphragm preparation of the rat
6. The action of snake venoms on nerve and muscle
7. An enzyme-linked immunosorbent assay (ELISA) that discriminates between the venoms of Brazilian Bothrops species and Crotalus durissus
8. Pesticide induced muscle necrosis: Mechanisms and prevention
9. Cross-reactivity of horse monovalent antivenoms to venoms of ten Bothrops species
10. A eficácia do antiveneno botrópico-crotálico na neutralização das principais atividades do veneno de Bothrops jararacussu
11. Purification and properties of crotamine
12. Myonecrosis hemorrhage and edema induced by Bothrops asper venom in white mice
13. Fractionation of Bothrops jararacussu snake venom: Partial chemical characterization and biological activity of bothropstoxin
14. 4
15. Crotoxin induces aggregation of human washed platelets
16. 2 from Bothrops asper snake venom
17. 2 from Bothrops asper snake venom by glycosaminoglycans of the heparin/heparan sulfate family
18. Antagonism of the myotoxic effects of Bothrops jararacussu venom and bothropstoxin by polyanions
19. 2 myotoxins
20. Release of creatine kinase from skeletal muscles by Bothrops venoms: Heparin potentiation of inhibition by antivenin
21. Release of sarcoplasmic enzymes from skeletal muscle by Bothrops jararacussu venom: Antagonism by heparin and by the serum of South American marsupials
22. Molecular immunology of snake toxins
23. Snake bites by the jararacuçu (Bothrops jararacussu): Clinicopathological studies of 29 proven cases in São Paulo State
24. Neutralizing capacity of antisera raised in horses and rabbits against Crotalus durissus terrificus (South American rattlesnake) venom and its main toxin, crotoxin
25. Neutralizing capacity of commercial bothropic antivenom against Bothrops jararacussu venom and bothropstoxin-I
26. Antigen-antibody reactions in gels
27. A simplification of the protein assay method of Lowry et al. which is more generally applicable
28. Heparin-induced skin reaction due to two different preparations of low molecular weight heparin
29. The effects of Bothrops jararacussu venom and its components on frog nerve-muscle preparation
30. Snake venom immunology: Historical and practical considerations
31. Heparin solubilizes asymmetric acetylcholinesterase from rat neuromuscular junction
32. Interaction of heparin with multimolecular aggregates of acetylcholinesterase
33. Heparin-induced skin reaction
34. Pharmacology of crystalline crotoxin. II. Neuromuscular blocking action
35. Treatment in a heparin-induced skin reaction with a low-molecular heparin analog