Absence of Poly(ADP-ribose) Polymerase-1 Alters Nuclear Factor-κB Activation and Gene Expression of Apoptosis Regulators after Reperfusion Injury

Molecular Medicine

Volumn 9, Issue 5-8, 2003, Pages 143-153

  Zingarelli, Basilia ^a   Hake, Paul W ^a   O'Connor, Michael ^a   Denenberg, Alvin ^a   Kong, Sue ^a   Aronow, Bruce J ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE 3; CREATINE KINASE; DNA; DNA FRAGMENT; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DEVICE; DNA BINDING; DNA MICROARRAY; ENZYME ACTIVATION; GENE EXPRESSION; GENOTYPE; HEART INFARCTION; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MEASUREMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; REPERFUSION INJURY; WESTERN BLOTTING; WILD TYPE;

EID: 0142240271     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03402179     Document Type: Article

References (53)

1. Ferrari R et al. (1998) Oxidative stress during myocardial ischaemia and heart failure. Eur. Heart J. 19:B2-11.
2. Grisham MB, Granger DN, Lefer DJ. (1998) Modulation of leukocyte-endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease. Free Radic. Biol. Med. 25:404-33.
3. Colucci WS. (1996) Apoptosis in the heart. N. Engl. J. Med. 335:1224-6.
4. Baeuerle PA. (1998) IκB-NF-κB structures: at the interface of inflammation control. Cell. 11:729-31.
5. Maulik N, Goswami S, Galang N, Das DK (1999). Differential regulation of Bcl-2, AP-1 and NF-κB on cardiomyocyte apoptosis during myocardial ischemic stress adaptation. FEBS Lett. 443:331-6.
6. Karin M, Delhase M. (2000) The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signaling. Semin. Immunol. 12:85-98.
7. Zingarelli B, O'Connor M, Wong H, Salzman AL, Szabó C. (1996) Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J. Immunol. 156:350-8.
8. Althaus FR, Richter C. (1987) ADP-ribosylation of proteins. Enzymology and biological significance. Mol. Biol. Biochem. Biophys. 37:1-237.
9. Lautier D, Lagueux J, Thibodeau J, Ménard L, Poirier GG. (1993) Molecular and biochemical features of poly (ADP-ribose) metabolism. Mol. Cell Biochem. 122:171-93.
10. Cochrane CG. (1991) Mechanisms of oxidant injury of cells. Molec. Aspects Med. 12:137-47.
11. Zhang J, Dawson VL, Dawson TM, Snyder SH. (1994) Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity. Science 263:687-9.
12. Kasid UN, Halligan B, Liu LF, Dritschilo A, Smulson ME. (1989) Poly (ADP-ribose) mediated post-translational modification of chromatin-associated human topoisomerase I. Inhibitory effects on catalytic activity. J. Biol. Chem. 264:18687-92.
13. Desmarais Y, Ménard L, Lagueux J, Poirier GG. (1991) Enzymological properties of poly (ADP-ribose) polymerase: Characterization of automodification sites and of its NADase activity. Biochem. Biophys. Acta. 1078:179-86.
14. D'Amours D, Desnoyers S, D'Silva I, Poirier GG. (1999) Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J. 342:249-68.
15. D'Silva I et al. (1999) Relative affinities of poly (ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions. Biochim. Biophys. Acta. 1430:119-26.
16. Szabó C, Dawson VL. (1998) Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion. Trends Pharmacol. Sci. 19:287-98.
17. ZingarelliB, Cuzzocrea S, Zsengeller Z, Salzman AL, Szabó C. (1997) Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase. Cacdiovasc. Res. 36:205-12.
18. Zingarelli B, Salzman AL, Szabó C. (1998) Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. Circ. Res. 83:85-94.
19. Yang Z, Zingarelli B, Szabó C. (2000) Effect of genetic disruption of poly (ADP-ribose) synthetase on delayed production of inflammatory mediators and delayed necrosis during myocardial ischemia-reperfusion injury. Shock 13:60-6.
20. Liaudet L, Soriano FG, Szabó E, Virag L, Mabley JG, Salzman AL, Szabó C. (2000) Protection against hemorrhagic shock in mice genetically deficient in poly (ADP-ribose)polymerase. Proc. Natl. Acad. Sci. U.S.A. 97:10203-8.
21. Eliasson M et al. (1997) Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat. Med. 3:1089-95.
22. Pieper AA et al. (1999) Poly (ADP-ribose) polymerase deficient mice are protected from streptozotocin-induced diabetes. Proc. Natl. Acad. Sci. U.S.A. 96:3059-64.
23. Szabó C et al. (1998) Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly (ADP-ribose) synthase. Proc. Natl. Acad. Sci. U.S.A. 95:3867-72.
24. Zingarelli B, Szabó C, Salzman AL. (1999) Blockade of poly (ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis. Gastroenterology 116:335-45.
25. Zingarelli B, Hake PW, Yang Z, O'Connor M, Denenberg A, Wong HR. (2002) Absence of inducible nitric oxide synthase modulates early reperfusion-induced NF-κB and AP-1 activation and enhances myocardial damage. FASE8 J. 16:327-42.
26. Vanags DM, Orrenius S, Aguilar-Santelises M. (1997) Alterations in Bcl-2/Bax protein levels in platelets form part of an ionomycin-induced process that resembles apoptosis. 8r. J. Haematol. 99:824-31.
27. Byrne MC, Whitley MZ, Follettie MT. (2000) Preparation of mRNA for expression monitoring. In: Current protocols in molecular biology. 4th ed. Ausubel FM (ed.) John Wiley and Sons, Inc., New York, N.Y. p. 22.2.1-22.2.13.
28. Zhang J, Xu M, Aronow B. (2002) Expression profiles of 109 apoptosis pathway-related genes in 82 mouse tissues and experimental conditions. Biochem. Biophys. Res. Commun. 297:537-44.
29. Villa P, Kaufmann SH, Earnshaw WC. (1997) Caspases and caspase inhibitors. Trends Biochem. Sci. 22:388-93.
30. Duan H, Orth K, Chinnaiyan AM, Poirier GG, Froelich CJ, He WW, Dixit VM. (1996) ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B. J. Biol. Chem. 271:16720-4.
31. Casciola-Rosen L, Nicholson DW, Chang T, Rowan KR, Thornberry NA, Miller DK, Rosen A. (1996) Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. J. Exp. Med. 183:1957-64.
32. Tewari M et al (1995). Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81:801-9.
33. Pieper AA, Verma A, Zhang J, Snyder SH (1999). Poly (ADP-ribose) polymerase, nitric oxide and cell death. Trends Phacmacol. Sci. 20:171-81.
34. Oliver FJ, de la Rubia G, Rolli V, Ruiz-Ruiz MC, de Murcia G, Murcia JM (1998). Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from on uncleavable mutant. J. Biol. Chem. 273:33533-9.
35. Plas DR, Thompson CB. (2002) Cell metabolism in the regulation of programmed cell death. Trends Endocrinol. Metab. 13:75-8.
36. Kroemer G. (1997) The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 3:614-20.
37. Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ (2001). BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell. 8:705-11.
38. Wei MC et al. (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science. 292:727-30.
39. Bais R, Edwards JB. (1982) Creatine kinase. Crit. Rev. Clin. Lab. Sci. 16:291-335.
40. Chandrasekar B, Freeman GL. (1997) Induction of nuclear foctor-κB and activation protein 1 in postischemic myocordium. FEBS Lett. 401:30-4.
41. Valen G, Hansson GK, Dumitrescu A, Vaage J. (2000) Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factors NF-κB and AP-1. Cardiovasc. Res. 47:49-56.
42. Schwartz GG. (2000) Exploring new strategies for the management of acute coronary syndromes. Am. J. Cardiol. 86:44J-9J.
43. Hassa PO, Hottiger MO. (1999) A role of poly (ADP-ribose) polymerase in NF-κB transcriptional activation. Biol. Chem. 380:953-9.
44. Oliver FJ et al. (1999) Resistance to endotoxic shock as a consequence of defective NF-κB activation in poly (ADP-ribose) polymerase-1 deficient mice. EMBO J. 18:4446-54.
45. Andreone TL, Denenberg A, O'Connor M, Hake PW, Zingarelli B. (2003) Poly (ADP-ribose) polymerase-1 regulates activation of activator protein-1 in murine fibroblasts. J. Immunol. 170:2113-20.
46. Zingarelli B, Hake PW, O'Connor M, Denenberg A. (2002) Absence of poly (ADP-ribose) polymerase-1 reduces apoptosis by modulation of activator protein-1 and heat shock factor-1 pathways during myocardial ischemia and reperfusion in mice. Circulation 106(Suppl.):11-91 (abs. 461), 2002.
47. Ha HC, Hester LD, Snyder SH. (2002) Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia. Proc. Natl. Acad. Sci. U.S.A. 99:3270-5.
48. Kameoka M, Ota K, Tetsuka T, Tanaka Y, Itaya A, Okamoto T, Yoshihara K. (2000) Evidence for regulation of NF-κB by poly(ADP-ribose) polymerase. Biochem. J. 346:641-9.
49. Kannan P, Yu Y, Wankhade S, Tainsky MA. (1999) PolyADP-ribose polymerase is a cooctivator for AP-2-mediated transcriptional activation. Nucleic Acids Res. 27:866-74.
50. Nie J, Sakamoto S, Song D, Qu Z, Ota K, Taniguchi T. (1998) Interaction of Oct-1 and automodification domain of poly(ADP-ribose) synthetase. FEBS Lett. 424: 27-32.
51. Oei SL, Griesenbeck J, Schweiger M, Babich V, Kropotov A, Tomilin N. (1997) Interaction of the transcription factor YY1 with human poly(ADP-ribosyl) transferase. Biochem. Biophys. Res. Commun. 240:108-11.
52. Butler AJ, Ordahl CP. (1999) Poly(ADP-ribose) polymerase binds with transcription enhancer factor 1 to MCAT1 elements to regulate muscle-specific transcription. Mol. Cell Biol. 19:296-306.
53. Hassa PO, Covic M, Hason S, Imhof R, Hottiger MO. (2001) The enzymatic and DNA binding activity of PARP-1 are not required for NF-κB coactivator function. J. Biol. Chem. 276:45588-97.