A PP2A active site mutant impedes growth and causes misregulation of native catalytic subunit expression

Journal of Cellular Biochemistry

Volumn 103, Issue 4, 2008, Pages 1309-1325

  Lizotte, Donna L ^a,b   Blakeslee, Joshua J ^a   Siryaporn, Albert ^a,c   Heath, Jeffrey T ^a   DeLong, Alison ^a,d  

^a BROWN UNIVERSITY   (United States)

^b BRYANT UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d Sidney Frank Hall for the Life Sciences ^*  (United States)

Author keywords

Catalytic site mutant; G1 phase delay; Protein phosphatase 2A; Regulated protein turnover

Indexed keywords

PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEASOME;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENE;

CATALYTIC DOMAIN; CELL CYCLE; CELL LINE; CELL PROLIFERATION; FIBROBLASTS; HUMANS; MUTATION; PROTEIN PHOSPHATASE 2; PROTEIN SUBUNITS;

EID: 40349114503     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21514     Document Type: Article

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