-
1
-
-
33746152372
-
Adipose tissue as a secretory organ: from adipogenesis to the metabolic syndrome
-
[discussion 653-575]
-
Ailhaud G. Adipose tissue as a secretory organ: from adipogenesis to the metabolic syndrome. C R Biol 329 (2006) 570-577 [discussion 653-575]
-
(2006)
C R Biol
, vol.329
, pp. 570-577
-
-
Ailhaud, G.1
-
2
-
-
33645280927
-
Childhood obesity: trends and potential causes
-
Anderson P.M., and Butcher K.E. Childhood obesity: trends and potential causes. Future Child 16 (2006) 19-45
-
(2006)
Future Child
, vol.16
, pp. 19-45
-
-
Anderson, P.M.1
Butcher, K.E.2
-
3
-
-
0036827697
-
Evidence for the existence of distinct central appetite and energy expenditure pathways and stimulation of ghrelin as revealed by hypothalamic site-specific leptin gene therapy
-
Bagnasco M., Dube M.G., Kalra P.S., and Kalra S.P. Evidence for the existence of distinct central appetite and energy expenditure pathways and stimulation of ghrelin as revealed by hypothalamic site-specific leptin gene therapy. Endocrinology 143 (2002) 4409-4421
-
(2002)
Endocrinology
, vol.143
, pp. 4409-4421
-
-
Bagnasco, M.1
Dube, M.G.2
Kalra, P.S.3
Kalra, S.P.4
-
4
-
-
2142687620
-
Leptin expression in hypothalamic PVN reverses dietary obesity and hyperinsulinemia but stimulates ghrelin
-
Bagnasco M., Dube M.G., Katz A., Kalra P.S., and Kalra S.P. Leptin expression in hypothalamic PVN reverses dietary obesity and hyperinsulinemia but stimulates ghrelin. Obes Res. 11 (2003) 1463-1470
-
(2003)
Obes Res.
, vol.11
, pp. 1463-1470
-
-
Bagnasco, M.1
Dube, M.G.2
Katz, A.3
Kalra, P.S.4
Kalra, S.P.5
-
5
-
-
0036963628
-
Leptin-from a signal of adiposity to a hormonal mediator in peripheral tissues
-
Baratta M. Leptin-from a signal of adiposity to a hormonal mediator in peripheral tissues. Med Sci Monit 8 (2002) RA282-RA292
-
(2002)
Med Sci Monit
, vol.8
-
-
Baratta, M.1
-
6
-
-
85047681825
-
Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: effects on serum ghrelin and appetite-regulating genes
-
Beretta E., Dube M.G., Kalra P.S., and Kalra S.P. Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: effects on serum ghrelin and appetite-regulating genes. Pediatr Res 52 (2002) 189-198
-
(2002)
Pediatr Res
, vol.52
, pp. 189-198
-
-
Beretta, E.1
Dube, M.G.2
Kalra, P.S.3
Kalra, S.P.4
-
7
-
-
33750948987
-
Hypothalamic clamp on insulin release by leptin-transgene expression
-
Boghossian S., Dube M.G., Torto R., Kalra P.S., and Kalra S.P. Hypothalamic clamp on insulin release by leptin-transgene expression. Peptides 27 (2006) 3245-3254
-
(2006)
Peptides
, vol.27
, pp. 3245-3254
-
-
Boghossian, S.1
Dube, M.G.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
8
-
-
22544464405
-
Suppression of fat deposition for the life time of rodents with gene therapy
-
Boghossian S., Lecklin A.H., Torto R., Kalra P.S., and Kalra S.P. Suppression of fat deposition for the life time of rodents with gene therapy. Peptides 26 (2005) 1512-1519
-
(2005)
Peptides
, vol.26
, pp. 1512-1519
-
-
Boghossian, S.1
Lecklin, A.H.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
9
-
-
34547770365
-
Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin
-
Boghossian S., Ueno N., Dube M.G., Kalra P., and Kalra S. Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin. Neurobiol Aging 28 (2007) 1594-1604
-
(2007)
Neurobiol Aging
, vol.28
, pp. 1594-1604
-
-
Boghossian, S.1
Ueno, N.2
Dube, M.G.3
Kalra, P.4
Kalra, S.5
-
10
-
-
2942683422
-
Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk
-
Carr M.C., and Brunzell J.D. Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk. J Clin Endocrinol Metab 89 (2004) 2601-2607
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2601-2607
-
-
Carr, M.C.1
Brunzell, J.D.2
-
11
-
-
33645746168
-
Induction of leptin resistance through direct interaction of C-reactive protein with leptin
-
Chen K., Li F., Li J., Cai H., Strom S., Bisello A., et al. Induction of leptin resistance through direct interaction of C-reactive protein with leptin. Nat Med 12 (2006) 425-432
-
(2006)
Nat Med
, vol.12
, pp. 425-432
-
-
Chen, K.1
Li, F.2
Li, J.3
Cai, H.4
Strom, S.5
Bisello, A.6
-
12
-
-
0034714042
-
Long-term differential modulation of genes encoding orexigenic and anorexigenic peptides by leptin delivered by rAAV vector in ob/ob mice. Relationship with body weight change
-
Dhillon H., Ge Y., Minter R.M., Prima V., Moldawer L.L., Muzyczka N., et al. Long-term differential modulation of genes encoding orexigenic and anorexigenic peptides by leptin delivered by rAAV vector in ob/ob mice. Relationship with body weight change. Regul Pept 92 (2000) 97-105
-
(2000)
Regul Pept
, vol.92
, pp. 97-105
-
-
Dhillon, H.1
Ge, Y.2
Minter, R.M.3
Prima, V.4
Moldawer, L.L.5
Muzyczka, N.6
-
13
-
-
0034882656
-
Dose-dependent effects of central leptin gene therapy on genes that regulate body weight and appetite in the hypothalamus
-
Dhillon H., Kalra S.P., and Kalra P.S. Dose-dependent effects of central leptin gene therapy on genes that regulate body weight and appetite in the hypothalamus. Mol Ther 4 (2001) 139-145
-
(2001)
Mol Ther
, vol.4
, pp. 139-145
-
-
Dhillon, H.1
Kalra, S.P.2
Kalra, P.S.3
-
14
-
-
0035876708
-
Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study
-
Dhillon H., Kalra S.P., Prima V., Zolotukhin S., Scarpace P.J., Moldawer L.L., et al. Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study. Regul Pept 99 (2001) 69-77
-
(2001)
Regul Pept
, vol.99
, pp. 69-77
-
-
Dhillon, H.1
Kalra, S.P.2
Prima, V.3
Zolotukhin, S.4
Scarpace, P.J.5
Moldawer, L.L.6
-
15
-
-
0036263327
-
Central leptin gene therapy blocks high fat diet-induced weight gain, hyperleptinemia and hyperinsulinemia: effects on serum ghrelin levels
-
Dube M.G., Beretta E., Dhillon H., Ueno N., Kalra P.S., and Kalra S.P. Central leptin gene therapy blocks high fat diet-induced weight gain, hyperleptinemia and hyperinsulinemia: effects on serum ghrelin levels. Diabetes 51 (2002) 1729-1736
-
(2002)
Diabetes
, vol.51
, pp. 1729-1736
-
-
Dube, M.G.1
Beretta, E.2
Dhillon, H.3
Ueno, N.4
Kalra, P.S.5
Kalra, S.P.6
-
16
-
-
18144408371
-
Adipose tissue, adipokines, and inflammation
-
Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 115 (2005) 911-919
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 911-919
-
-
Fantuzzi, G.1
-
17
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman J.M., and Halaas J.L. Leptin and the regulation of body weight in mammals. Nature 395 (1998) 763-770
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
18
-
-
10044289719
-
Role of adipocytokines in metabolism and disease
-
Fruhbeck G., and Salvador J. Role of adipocytokines in metabolism and disease. Nutr Res 24 (2004) 803-826
-
(2004)
Nutr Res
, vol.24
, pp. 803-826
-
-
Fruhbeck, G.1
Salvador, J.2
-
19
-
-
2942675088
-
Obesity, metabolic syndrome, and cardiovascular disease
-
Grundy S.M. Obesity, metabolic syndrome, and cardiovascular disease. J Clin Endocrinol Metab 89 (2004) 2595-2600
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2595-2600
-
-
Grundy, S.M.1
-
20
-
-
0032577404
-
Environmental contributions to the obesity epidemic
-
Hill J.O., and Peters J.C. Environmental contributions to the obesity epidemic. Science 280 (1998) 1371-1374
-
(1998)
Science
, vol.280
, pp. 1371-1374
-
-
Hill, J.O.1
Peters, J.C.2
-
21
-
-
1942440850
-
Leptin and the proinflammatory state associated with human obesity
-
Hukshorn C.J., Lindeman J.H., Toet K.H., Saris W.H., Eilers P.H., Westerterp-Plantenga M.S., et al. Leptin and the proinflammatory state associated with human obesity. J Clin Endocrinol Metab 89 (2004) 1773-1778
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1773-1778
-
-
Hukshorn, C.J.1
Lindeman, J.H.2
Toet, K.H.3
Saris, W.H.4
Eilers, P.H.5
Westerterp-Plantenga, M.S.6
-
22
-
-
34247546688
-
Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice
-
Iwaniec U.T., Boghossian S., Lapke P.D., Turner R.T., and Kalra S.P. Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice. Peptides 28 (2007) 1012-1019
-
(2007)
Peptides
, vol.28
, pp. 1012-1019
-
-
Iwaniec, U.T.1
Boghossian, S.2
Lapke, P.D.3
Turner, R.T.4
Kalra, S.P.5
-
23
-
-
37249046860
-
Central leptin insufficiency syndrome: An interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions
-
Kalra S.P. Central leptin insufficiency syndrome: An interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions. Peptides 29 (2008) 127-138
-
(2008)
Peptides
, vol.29
, pp. 127-138
-
-
Kalra, S.P.1
-
24
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra S.P., Dube M.G., Pu S., Xu B., Horvath T.L., and Kalra P.S. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20 (1999) 68-100
-
(1999)
Endocr Rev
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
Dube, M.G.2
Pu, S.3
Xu, B.4
Horvath, T.L.5
Kalra, P.S.6
-
25
-
-
25144507707
-
Gene transfer technology: a preventive neurotherapy to curb obesity, ameliorate metabolic syndrome and extend life-expectancy
-
Kalra S.P., and Kalra P.S. Gene transfer technology: a preventive neurotherapy to curb obesity, ameliorate metabolic syndrome and extend life-expectancy. Trends Pharmacol Sci 26 (2005) 488-495
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 488-495
-
-
Kalra, S.P.1
Kalra, P.S.2
-
26
-
-
0041733148
-
Keeping obesity and metabolic syndrome at bay with central leptin and cytokine gene therapy
-
Hamilton I. (Ed), Bentham Science Publishers Ltd., San Francisco, CA
-
Kalra S.P., and Kalra P.S. Keeping obesity and metabolic syndrome at bay with central leptin and cytokine gene therapy. In: Hamilton I. (Ed). Current medicinal chemistry-central nervous system agent (2003), Bentham Science Publishers Ltd., San Francisco, CA 189-199
-
(2003)
Current medicinal chemistry-central nervous system agent
, pp. 189-199
-
-
Kalra, S.P.1
Kalra, P.S.2
-
27
-
-
33646529141
-
Serum C-reactive protein as a marker for wellness assessment
-
Kao P.C., Shiesh S.C., and Wu T.J. Serum C-reactive protein as a marker for wellness assessment. Ann Clin Lab Sci 36 (2006) 163-169
-
(2006)
Ann Clin Lab Sci
, vol.36
, pp. 163-169
-
-
Kao, P.C.1
Shiesh, S.C.2
Wu, T.J.3
-
28
-
-
0141459376
-
C-reactive protein in young, apparently healthy men: associations with serum leptin, QTc interval, and high-density lipoprotein-cholesterol
-
Kazumi T., Kawaguchi A., Hirano T., and Yoshino G. C-reactive protein in young, apparently healthy men: associations with serum leptin, QTc interval, and high-density lipoprotein-cholesterol. Metabolism 52 (2003) 1113-1116
-
(2003)
Metabolism
, vol.52
, pp. 1113-1116
-
-
Kazumi, T.1
Kawaguchi, A.2
Hirano, T.3
Yoshino, G.4
-
30
-
-
33748420067
-
Biomarkers of outcome from cardiovascular disease
-
Khuseyinova N., and Koenig W. Biomarkers of outcome from cardiovascular disease. Curr Opin Crit Care 12 (2006) 412-419
-
(2006)
Curr Opin Crit Care
, vol.12
, pp. 412-419
-
-
Khuseyinova, N.1
Koenig, W.2
-
31
-
-
32644451260
-
Tracing from fat tissue, liver, and pancreas: a neuroanatomical framework for the role of the brain in type 2 diabetes
-
Kreier F., Kap Y.S., Mettenleiter T.C., van Heijningen C., van der Vliet J., Kalsbeek A., et al. Tracing from fat tissue, liver, and pancreas: a neuroanatomical framework for the role of the brain in type 2 diabetes. Endocrinology 147 (2006) 1140-1147
-
(2006)
Endocrinology
, vol.147
, pp. 1140-1147
-
-
Kreier, F.1
Kap, Y.S.2
Mettenleiter, T.C.3
van Heijningen, C.4
van der Vliet, J.5
Kalsbeek, A.6
-
32
-
-
20444421276
-
Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation
-
Lecklin A.H., Dube M.G., Torto R., Kalra P.S., and Kalra S.P. Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation. Peptides 26 (2005) 1176-1187
-
(2005)
Peptides
, vol.26
, pp. 1176-1187
-
-
Lecklin, A.H.1
Dube, M.G.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
33
-
-
0038577223
-
Minireview: adiposity, inflammation, and atherogenesis
-
Lyon C.J., Law R.E., and Hsueh W.A. Minireview: adiposity, inflammation, and atherogenesis. Endocrinology 144 (2003) 2195-2200
-
(2003)
Endocrinology
, vol.144
, pp. 2195-2200
-
-
Lyon, C.J.1
Law, R.E.2
Hsueh, W.A.3
-
34
-
-
0035431169
-
The effects of leptin administration in non-obese human subjects
-
Mackintosh R.M., and Hirsch J. The effects of leptin administration in non-obese human subjects. Obes Res 9 (2001) 462-469
-
(2001)
Obes Res
, vol.9
, pp. 462-469
-
-
Mackintosh, R.M.1
Hirsch, J.2
-
35
-
-
0030735542
-
Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo
-
Mohamed-Ali V., Goodrick S., Rawesh A., Katz D.R., Miles J.M., Yudkin J.S., et al. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J Clin Endocrinol Metab 82 (1997) 4196-4200
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 4196-4200
-
-
Mohamed-Ali, V.1
Goodrick, S.2
Rawesh, A.3
Katz, D.R.4
Miles, J.M.5
Yudkin, J.S.6
-
36
-
-
34247622463
-
Role of novel biomarkers of inflammation in patients with stable coronary heart disease
-
Oren H., Erbay A.R., Balci M., and Cehreli S. Role of novel biomarkers of inflammation in patients with stable coronary heart disease. Angiology 58 (2007) 148-155
-
(2007)
Angiology
, vol.58
, pp. 148-155
-
-
Oren, H.1
Erbay, A.R.2
Balci, M.3
Cehreli, S.4
-
37
-
-
27944502118
-
Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight
-
Otukonyong E.E., Dube M.G., Torto R., Kalra P.S., and Kalra S.P. Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight. Peptides 26 (2005) 2559-2566
-
(2005)
Peptides
, vol.26
, pp. 2559-2566
-
-
Otukonyong, E.E.1
Dube, M.G.2
Torto, R.3
Kalra, P.S.4
Kalra, S.P.5
-
38
-
-
20444480549
-
Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-alpha and IL-6
-
Park H.S., Park J.Y., and Yu R. Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-alpha and IL-6. Diabetes Res Clin Pract 69 (2005) 29-35
-
(2005)
Diabetes Res Clin Pract
, vol.69
, pp. 29-35
-
-
Park, H.S.1
Park, J.Y.2
Yu, R.3
-
39
-
-
0037469232
-
Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association
-
Pearson T.A., Mensah G.A., Alexander R.W., Anderson J.L., Cannon III R.O., Criqui M., et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 107 (2003) 499-511
-
(2003)
Circulation
, vol.107
, pp. 499-511
-
-
Pearson, T.A.1
Mensah, G.A.2
Alexander, R.W.3
Anderson, J.L.4
Cannon III, R.O.5
Criqui, M.6
-
40
-
-
33646448307
-
Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss
-
Poirier P., Giles T.D., Bray G.A., Hong Y., Stern J.S., Pi-Sunyer F.X., et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss. Arterioscler Thromb Vasc Biol 26 (2006) 968-976
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 968-976
-
-
Poirier, P.1
Giles, T.D.2
Bray, G.A.3
Hong, Y.4
Stern, J.S.5
Pi-Sunyer, F.X.6
-
41
-
-
0041374029
-
Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha
-
Ruan H., and Lodish H.F. Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha. Cytokine Growth Factor Rev 14 (2003) 447-455
-
(2003)
Cytokine Growth Factor Rev
, vol.14
, pp. 447-455
-
-
Ruan, H.1
Lodish, H.F.2
-
42
-
-
2442581240
-
Independent association between plasma leptin and C-reactive protein in healthy humans
-
Shamsuzzaman A.S., Winnicki M., Wolk R., Svatikova A., Phillips B.G., Davison D.E., et al. Independent association between plasma leptin and C-reactive protein in healthy humans. Circulation 109 (2004) 2181-2185
-
(2004)
Circulation
, vol.109
, pp. 2181-2185
-
-
Shamsuzzaman, A.S.1
Winnicki, M.2
Wolk, R.3
Svatikova, A.4
Phillips, B.G.5
Davison, D.E.6
-
44
-
-
0035161705
-
Neuroanatomical specificity of the circuits controlling sympathetic outflow to different targets
-
Sved A.F., Cano G., and Card J.P. Neuroanatomical specificity of the circuits controlling sympathetic outflow to different targets. Clin Exp Pharmacol Physiol 28 (2001) 115-119
-
(2001)
Clin Exp Pharmacol Physiol
, vol.28
, pp. 115-119
-
-
Sved, A.F.1
Cano, G.2
Card, J.P.3
-
45
-
-
27844545767
-
Signalling role of adipose tissue: adipokines and inflammation in obesity
-
Trayhurn P., and Wood I.S. Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem Soc Trans 33 (2005) 1078-1081
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 1078-1081
-
-
Trayhurn, P.1
Wood, I.S.2
-
46
-
-
4344675633
-
Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy
-
Ueno N., Dube M.G., Inui A., Kalra P.S., and Kalra S.P. Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy. Endocrinology 145 (2004) 4176-4184
-
(2004)
Endocrinology
, vol.145
, pp. 4176-4184
-
-
Ueno, N.1
Dube, M.G.2
Inui, A.3
Kalra, P.S.4
Kalra, S.P.5
-
47
-
-
33746886648
-
Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice
-
Ueno N., Inui A., Kalra S.P., and Kalra P.S. Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice. Peptides 27 (2006) 2332-2342
-
(2006)
Peptides
, vol.27
, pp. 2332-2342
-
-
Ueno, N.1
Inui, A.2
Kalra, S.P.3
Kalra, P.S.4
-
49
-
-
0037133285
-
Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year
-
Ziccardi P., Nappo F., Giugliano G., Esposito K., Marfella R., Cioffi M., et al. Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation 105 (2002) 804-809
-
(2002)
Circulation
, vol.105
, pp. 804-809
-
-
Ziccardi, P.1
Nappo, F.2
Giugliano, G.3
Esposito, K.4
Marfella, R.5
Cioffi, M.6
|