The cys-loop ligand-gated ion channel gene superfamily of the nematode, Caenorhabditis elegans

Invertebrate Neuroscience

Volumn 8, Issue 1, 2008, Pages 41-47

  Jones, Andrew K ^a   Sattelle, David B ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Acetylcholine; Caenorhabditis elegans; GABA; Glutamate; Ion channel; Serotonin

Indexed keywords

ION CHANNEL;

ARTICLE; CAENORHABDITIS ELEGANS; MULTIGENE FAMILY; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CYSTEINE; ION CHANNELS; LIGANDS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 40149101376     PISSN: 13542516     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10158-008-0068-4     Document Type: Article

References (49)

1. Bamber BA, Beg AA, Twyman RE, Jorgensen EM (1999) The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor. J Neurosci 19:5348-5359
2. Bargmann CI (1998) Neurobiology of the Caenorhabditis elegans genome. Science 282:2028-2033
3. Beg AA, Jorgensen EM (2003) EXP-1 is an excitatory GABA-gated cation channel. Nat Neurosci 6:1145-1152
4. Benner SA, Cohen MA, Gonnet GH (1994) Amino acid substitution during functionally constrained divergent evolution of protein sequences. Protein Eng 7:1323-1332
5. Bocquet N, Prado de Carvalho L, Cartaud J, Neyton J, Le Poupon C, Taly A, Grutter T, Changeux JP, Corringer PJ (2007) A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature 445:116-119
6. Bormann J (2000) The 'ABC' of GABA receptors. Trends Pharmacol Sci 21:16-19
7. Brown LA, Jones AK, Buckingham SD, Mee CJ, Sattelle DB (2006) Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study. Int J Parasitol 36:617-624
8. Buckingham SD, Biggin PC, Sattelle BM, Brown LA, Sattelle DB (2005) Insect GABA receptors: splicing, editing, and targeting by antiparasitics and insecticides. Mol Pharmacol 68:942-951
9. Chalasani SH, Chronis N, Tsunozaki M, Gray JM, Ramot D, Goodman MB, Bargmann CI (2007) Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans. Nature 450:63-70
10. Cook A, Aptel N, Portillo V, Siney E, Sihota R, Holden-Dye L, Wolstenholme A (2006) Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors. Mol Biochem Parasitol 147:118-125
11. Corringer PJ, Le Novere N, Changeux JP (2000) Nicotinic receptors at the amino acid level. Annu Rev Pharmacol Toxicol 40:431-458
12. Darlison MG, Pahal I, Thode C (2005) Consequences of the evolution of the GABA(A) receptor gene family. Cell Mol Neurobiol 25:607-624
13. Dent JA (2006) Evidence for a diverse cys-loop ligand-gated ion channel superfamily in early bilateria. J Mol Evol 62:523-535
14. Dent JA, Davis MW, Avery L (1997) avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans. EMBO J 16:5867-5879
15. Feng XP, Hayashi J, Beech RN, Prichard RK (2002) Study of the nematode putative GABA type-A receptor subunits: evidence for modulation by ivermectin. J Neurochem 83:870-878
16. Gisselmann G, Pusch H, Hovemann BT, Hatt H (2002) Two cDNAs coding for histamine-gated ion channels in D. melanogaster. Nat Neurosci 5:11-12
17. Green WN, Wanamaker CP (1997) The role of the cystine loop in acetylcholine receptor assembly. J Biol Chem 272:20945-20953
18. Grutter T, de Carvalho LP, Dufresne V, Taly A, Edelstein SJ, Changeux JP (2005) Molecular tuning of fast gating in pentameric ligand-gated ion channels. Proc Natl Acad Sci U S A 102:18207-18212
19. Gupta BP, Johnsen R, Chen N (2007) Genomics and biology of the nematode Caenorhabditis briggsae. WormBook 1-16
20. Jensen ML, Schousboe A, Ahring PK (2005) Charge selectivity of the Cys-loop family of ligand-gated ion channels. J Neurochem 92:217-225
21. Jones AK, Davis P, Hodgkin J, Sattelle DB (2007) The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature. Invert Neurosci 7:129-131
22. Jones AK, Sattelle DB (2004) Functional genomics of the nicotinic acetylcholine receptor gene family of the nematode, Caenorhabditis elegans. Bioessays 26:39-49
23. Jones AK, Sattelle DB (2006) The cys-loop ligand-gated ion channel superfamily of the honeybee, Apis mellifera. Invert Neurosci 6:123-132
24. Jones AK, Sattelle DB (2007) The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum. BMC Genomics 8:327
25. Kalamida D, Poulas K, Avramopoulou V, Fostieri E, Lagoumintzis G, Lazaridis K, Sideri A, Zouridakis M, Tzartos SJ (2007) Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity. FEBS J 274:3799-3845
26. Kirsch J (2006) Glycinergic transmission. Cell Tissue Res 326:535-540
27. Laughton DL, Lunt GG, Wolstenholme AJ (1997) Reporter gene constructs suggest that the Caenorhabditis elegans avermectin receptor beta-subunit is expressed solely in the pharynx. J Exp Biol 200:1509-1514
28. Littleton JT, Ganetzky B (2000) Ion channels and synaptic organization: analysis of the Drosophila genome. Neuron 26:35-43
29. Mongan NP, Baylis HA, Adcock C, Smith GR, Sansom MS, Sattelle DB (1998) An extensive and diverse gene family of nicotinic acetylcholine receptor alpha subunits in Caenorhabditis elegans. Recept Channels 6:213-228
30. Page RD (1996) TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 12:357-358
31. Pemberton DJ, Franks CJ, Walker RJ, Holden-Dye L (2001) Characterization of glutamate-gated chloride channels in the pharynx of wild-type and mutant Caenorhabditis elegans delineates the role of the subunit GluCl-alpha2 in the function of the native receptor. Mol Pharmacol 59:1037-1043
32. Putrenko I, Zakikhani M, Dent JA (2005) A family of acetylcholine-gated chloride channel subunits in Caenorhabditis elegans. J Biol Chem 280:6392-6398
33. Ranganathan R, Cannon SC, Horvitz HR (2000) MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans. Nature 408:470-475
34. Reeves DC, Lummis SC (2002) The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review). Mol Membr Biol 19:11-26
35. Richmond JE, Jorgensen EM (1999) One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction. Nat Neurosci 2:791-797
36. Saitou N, Nei M (1987) The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4:406-425
37. Sattelle DB, Jones AK, Sattelle BM, Matsuda K, Reenan R, Biggin PC (2005) Edit, cut and paste in the nicotinic acetylcholine receptor gene family of Drosophila melanogaster. Bioessays 27:366-376
38. Schuske K, Beg AA, Jorgensen EM (2004) The GABA nervous system in C. elegans. Trends Neurosci 27:407-414
39. Sine SM, Engel AG (2006) Recent advances in Cys-loop receptor structure and function. Nature 440:448-455
40. Stein LD, Bao Z, Blasiar D, Blumenthal T, Brent MR, Chen N, Chinwalla A, Clarke L, Clee C, Coghlan A, Coulson A, D'Eustachio P, Fitch DH, Fulton LA, Fulton RE, Griffiths-Jones S, Harris TW, Hillier LW, Kamath R, Kuwabara PE, Mardis ER, Marra MA, Miner TL, Minx P, Mullikin JC, Plumb RW, Rogers J, Schein JE, Sohrmann M, Spieth J, Stajich JE, Wei C, Willey D, Wilson RK, Durbin R, Waterston RH (2003) The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol 1:E45
41. Tasneem A, Iyer LM, Jakobsson E, Aravind L (2005) Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels. Genome Biol 6:R4
42. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876-4882
43. van Nierop P, Keramidas A, Bertrand S, van Minnen J, Gouwenberg Y, Bertrand D, Smit AB (2005) Identification of molluscan nicotinic acetylcholine receptor (nAChR) subunits involved in formation of cation- and anion-selective nAChRs. J Neurosci 25:10617-10626
44. Vassilatis DK, Elliston KO, Paress PS, Hamelin M, Arena JP, Schaeffer JM, Van der Ploeg LH, Cully DF (1997) Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate-gated chloride channels. J Mol Evol 44:501-508
45. Williamson SM, Walsh TK, Wolstenholme AJ (2007) The cys-loop ligand-gated ion channel gene family of Brugia malayi and Trichinella spiralis: a comparison with Caenorhabditis elegans. Invert Neurosci 7:219-226
46. Wolstenholme AJ, Rogers AT (2005) Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics. Parasitology 131(Suppl):S85-95
47. Wotring VE, Weiss DS (2008) Charge scan reveals an extended region at the intracellular end of the GABA receptor pore that can influence ion selectivity. J Gen Physiol 131:87-97
48. Yates DM, Wolstenholme AJ (2004) Dirofilaria immitis: identification of a novel ligand-gated ion channel-related polypeptide. Exp Parasitol 108:182-185
49. Zheng Y, Hirschberg B, Yuan J, Wang AP, Hunt DC, Ludmerer SW, Schmatz DM, Cully DF (2002) Identification of two novel Drosophila melanogaster histamine-gated chloride channel subunits expressed in the eye. J Biol Chem 277:2000-2005