Synthesis and screening for antiacetylcholinesterase activity of (1-benzyl-4-oxopiperidin-3-ylidene)methylindoles and -pyrroles related to donepezil

Journal of Medicinal Chemistry

Volumn 44, Issue 23, 2001, Pages 4011-4014

  Andreani, A ^a   Cavalli, A ^a   Granaiola, M ^a   Guardigli, M ^a   Leoni, A ^a   Locatelli, A ^a   Morigi, R ^a   Rambaldi, M ^a   Recanatini, M ^a   Roda, A ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

(1 BENZYL 4 OXOPIPERIDIN 3 YLIDENE)METHYLINDOLE DERIVATIVE; CHOLINESTERASE INHIBITOR; DONEPEZIL; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHEMOLUMINESCENCE; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; MOLECULAR DYNAMICS; SIMULATION;

ACETYLCHOLINESTERASE; CHEMILUMINESCENT MEASUREMENTS; DRUG EVALUATION, PRECLINICAL; INDANS; INDOLES; MODELS, MOLECULAR; NOOTROPIC AGENTS; PIPERIDINES; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035829449     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0109356     Document Type: Article

References (8)

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