메뉴 건너뛰기




Volumn 18, Issue 1, 2008, Pages 39-43

Growth hormone therapy and risk of malignancy

Author keywords

Gowth hormone; Malignancy; Tumor

Indexed keywords

GROWTH HORMONE;

EID: 40049095676     PISSN: 10512144     EISSN: None     Source Type: Journal    
DOI: 10.1097/TEN.0b013e3181652369     Document Type: Review
Times cited : (1)

References (96)
  • 2
    • 0035115801 scopus 로고    scopus 로고
    • The somatomedin hypothesis: 2001
    • Le Roith D, Bondy C, Yakar S, et al. The somatomedin hypothesis: 2001. Endocr Rev. 2001;22:53-74.
    • (2001) Endocr Rev , vol.22 , pp. 53-74
    • Le Roith, D.1    Bondy, C.2    Yakar, S.3
  • 3
    • 0034907888 scopus 로고    scopus 로고
    • Signal transduction via the growth hormone receptor
    • Zhu T, Goh EL, Graichen R, et al. Signal transduction via the growth hormone receptor. Cell Signal. 2001;13:599-616.
    • (2001) Cell Signal , vol.13 , pp. 599-616
    • Zhu, T.1    Goh, E.L.2    Graichen, R.3
  • 4
    • 0025368959 scopus 로고
    • Effects of human growth hormone in men over 60 years old
    • Rudman D, Feller AG, Nagraj HS, et al. Effects of human growth hormone in men over 60 years old. N Engl J Med. 1990;323:1-6.
    • (1990) N Engl J Med , vol.323 , pp. 1-6
    • Rudman, D.1    Feller, A.G.2    Nagraj, H.S.3
  • 5
    • 27244440102 scopus 로고    scopus 로고
    • Provision or distribution of growth hormone for "antiaging": Clinical and legal issues
    • Perls TT, Reisman NR, Olshansky SJ. Provision or distribution of growth hormone for "antiaging": clinical and legal issues. JAMA. 2005; 294:2086-2090.
    • (2005) JAMA , vol.294 , pp. 2086-2090
    • Perls, T.T.1    Reisman, N.R.2    Olshansky, S.J.3
  • 6
    • 0038121116 scopus 로고    scopus 로고
    • Growth hormone therapy in adults
    • Cummings DE, Merriam GR. Growth hormone therapy in adults. Annu Rev Med. 2003;54:513-533.
    • (2003) Annu Rev Med , vol.54 , pp. 513-533
    • Cummings, D.E.1    Merriam, G.R.2
  • 7
    • 0030319373 scopus 로고    scopus 로고
    • Effects of physiologic growth hormone therapy on bone density and body composition in patients with adult-onset growth hormone deficiency. A randomized, placebo-controlled trial
    • Baum HB, Biller BM, Finkelstein JS, et al. Effects of physiologic growth hormone therapy on bone density and body composition in patients with adult-onset growth hormone deficiency. A randomized, placebo-controlled trial. Ann Intern Med. 1996;125:883-890.
    • (1996) Ann Intern Med , vol.125 , pp. 883-890
    • Baum, H.B.1    Biller, B.M.2    Finkelstein, J.S.3
  • 8
    • 0034453773 scopus 로고    scopus 로고
    • Withdrawal of long-term physiological growth hormone (GH) administration: Differential effects on bone density and body composition in men with adult-onset GH deficiency
    • Biller BM, Sesmilo G, Baum HB, et al. Withdrawal of long-term physiological growth hormone (GH) administration: differential effects on bone density and body composition in men with adult-onset GH deficiency. J Clin Endocrinol Metab. 2000;85:970-976.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 970-976
    • Biller, B.M.1    Sesmilo, G.2    Baum, H.B.3
  • 9
    • 2642536109 scopus 로고    scopus 로고
    • Aspects of growth hormone deficiency and replacement in elderly hypopituitary adults
    • Feldt-Rasmussen U, Wilton P, Jonsson P. Aspects of growth hormone deficiency and replacement in elderly hypopituitary adults. Growth Horm IGF Res. 2004;14(Suppl A):S51-S58.
    • (2004) Growth Horm IGF Res , vol.14 , Issue.SUPPL. A
    • Feldt-Rasmussen, U.1    Wilton, P.2    Jonsson, P.3
  • 10
    • 0038301176 scopus 로고    scopus 로고
    • Long-term experience with GH replacement therapy: Efficacy and safety
    • Monson JP. Long-term experience with GH replacement therapy: efficacy and safety. Eur J Endocrinol. 2003;148(Suppl 2):S9-S14.
    • (2003) Eur J Endocrinol , vol.148 , Issue.SUPPL. 2
    • Monson, J.P.1
  • 11
    • 33644543118 scopus 로고    scopus 로고
    • Growth hormone for antiaging
    • Hertoghe T, Schuder S. Growth hormone for "antiaging." JAMA. 2006; 295:888-890.
    • (2006) JAMA , vol.295 , pp. 888-890
    • Hertoghe, T.1    Schuder, S.2
  • 12
    • 33846901379 scopus 로고    scopus 로고
    • Systematic review: The safety and efficacy of growth hormone in the healthy elderly
    • Liu H, Bravata DM, Olkin I, et al. Systematic review: the safety and efficacy of growth hormone in the healthy elderly. Ann Intern Med. 2007;146:104-115.
    • (2007) Ann Intern Med , vol.146 , pp. 104-115
    • Liu, H.1    Bravata, D.M.2    Olkin, I.3
  • 13
    • 0027373309 scopus 로고
    • Carpal tunnel syndrome and gynaecomastia during growth hormone treatment of elderly men with low circulating IGF-I concentrations
    • Cohn L, Feller AG, Draper MW, et al. Carpal tunnel syndrome and gynaecomastia during growth hormone treatment of elderly men with low circulating IGF-I concentrations. Clin Endocrinol (Oxf). 1993;39: 417-425.
    • (1993) Clin Endocrinol (Oxf) , vol.39 , pp. 417-425
    • Cohn, L.1    Feller, A.G.2    Draper, M.W.3
  • 14
    • 0028146277 scopus 로고
    • Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women
    • Holloway L, Butterfield G, Hintz RL, et al. Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women. J Clin Endocrinol Metab. 1994;79:470-479.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 470-479
    • Holloway, L.1    Butterfield, G.2    Hintz, R.L.3
  • 16
    • 0033023320 scopus 로고    scopus 로고
    • GH replacement in 1034 growth hormone deficient hypopituitary adults: Demographic and clinical characteristics, dosing and safety
    • Abs R, Bengtsson BA, Hernberg-Stahl E, et al. GH replacement in 1034 growth hormone deficient hypopituitary adults: demographic and clinical characteristics, dosing and safety. Clin Endocrinol (Oxf). 1999;50: 703-713.
    • (1999) Clin Endocrinol (Oxf) , vol.50 , pp. 703-713
    • Abs, R.1    Bengtsson, B.A.2    Hernberg-Stahl, E.3
  • 17
    • 26644463217 scopus 로고    scopus 로고
    • Improvement in insulin sensitivity without concomitant changes in body composition and cardiovascular risk markers following fixed administration of a very low growth hormone (GH) dose in adults with severe GH deficiency
    • Yuen KC, Frystyk J, White DK, et al. Improvement in insulin sensitivity without concomitant changes in body composition and cardiovascular risk markers following fixed administration of a very low growth hormone (GH) dose in adults with severe GH deficiency. Clin Endocrinol (Oxf). 2005;63:428-436.
    • (2005) Clin Endocrinol (Oxf) , vol.63 , pp. 428-436
    • Yuen, K.C.1    Frystyk, J.2    White, D.K.3
  • 18
    • 0014772012 scopus 로고
    • Heart muscle disease in acromegaly
    • Pepine CJ, Aloia J. Heart muscle disease in acromegaly. Am J Med. 1970;48:530-534.
    • (1970) Am J Med , vol.48 , pp. 530-534
    • Pepine, C.J.1    Aloia, J.2
  • 19
    • 0034455408 scopus 로고    scopus 로고
    • Cardiovascular effects of short-term growth hormone hypersecretion
    • Fazio S, Cittadini A, Biondi B, et al. Cardiovascular effects of short-term growth hormone hypersecretion. J Clin Endocrinol Metab. 2000;85: 179-182.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 179-182
    • Fazio, S.1    Cittadini, A.2    Biondi, B.3
  • 20
    • 0033799471 scopus 로고    scopus 로고
    • Cardiac dysfunction in acromegaly: Evidence by pulsed wave tissue Doppler imaging
    • Mercuro G, Zoncu S, Colonna P, et al. Cardiac dysfunction in acromegaly: evidence by pulsed wave tissue Doppler imaging. Eur J Endocrinol. 2000;143:363-369.
    • (2000) Eur J Endocrinol , vol.143 , pp. 363-369
    • Mercuro, G.1    Zoncu, S.2    Colonna, P.3
  • 21
    • 0018891451 scopus 로고
    • Epidemiology of acromegaly in the Newcastle region
    • Alexander L, Appleton D, Hall R, et al. Epidemiology of acromegaly in the Newcastle region. Clin Endocrinol (Oxf). 1980;12:71-79.
    • (1980) Clin Endocrinol (Oxf) , vol.12 , pp. 71-79
    • Alexander, L.1    Appleton, D.2    Hall, R.3
  • 22
    • 0023886723 scopus 로고
    • Epidemiology and long-term survival in acromegaly: A study of 166 cases diagnosed between 1955 and 1984
    • Bengtsson BA, Eden S, Ernest I, et al. Epidemiology and long-term survival in acromegaly: a study of 166 cases diagnosed between 1955 and 1984. Acta Med Scand. 1988;223:327-335.
    • (1988) Acta Med Scand , vol.223 , pp. 327-335
    • Bengtsson, B.A.1    Eden, S.2    Ernest, I.3
  • 23
    • 0032884082 scopus 로고    scopus 로고
    • Growth hormone, IGF-I and cancer: Less intervention to avoid cancer? More intervention to prevent cancer?
    • Holly JM, Gunnell DJ, Davey Smith G. Growth hormone, IGF-I and cancer: less intervention to avoid cancer? More intervention to prevent cancer? J Endocrinol. 1999;162:321-330.
    • (1999) J Endocrinol , vol.162 , pp. 321-330
    • Holly, J.M.1    Gunnell, D.J.2    Davey Smith, G.3
  • 24
    • 0032499440 scopus 로고    scopus 로고
    • Circulating concentrations of insulin-like growth factor-I and risk of breast cancer
    • Hankinson SE, Willett WC, Colditz GA, et al. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet. 1998;351:1393-1396.
    • (1998) Lancet , vol.351 , pp. 1393-1396
    • Hankinson, S.E.1    Willett, W.C.2    Colditz, G.A.3
  • 25
    • 0032559272 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study
    • Chan JM, Stampfer MJ, Giovannucci E, et al. Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science. 1998;279: 563-566.
    • (1998) Science , vol.279 , pp. 563-566
    • Chan, J.M.1    Stampfer, M.J.2    Giovannucci, E.3
  • 26
    • 0034527640 scopus 로고    scopus 로고
    • Serum levels of insulinlike growth factor I (IGF-I), IGF-II, IGF-binding protein-3, and prostatespecific antigen as predictors of clinical prostate cancer
    • Harman SM, Metter EJ, Blackman MR, et al. Serum levels of insulinlike growth factor I (IGF-I), IGF-II, IGF-binding protein-3, and prostatespecific antigen as predictors of clinical prostate cancer. J Clin Endocrinol Metab. 2000;85:4258-4265.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4258-4265
    • Harman, S.M.1    Metter, E.J.2    Blackman, M.R.3
  • 27
    • 0033531765 scopus 로고    scopus 로고
    • Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
    • Ma J, Pollak MN, Giovannucci E, et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst. 1999;91:620-625.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 620-625
    • Ma, J.1    Pollak, M.N.2    Giovannucci, E.3
  • 28
    • 0035160628 scopus 로고    scopus 로고
    • Insulin, insulin-like growth factors and colon cancer: A review of the evidence
    • Giovannucci E. Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J Nutr. 2001;131:3109S-3120S.
    • (2001) J Nutr , vol.131
    • Giovannucci, E.1
  • 29
    • 17344367528 scopus 로고    scopus 로고
    • Long-term monitoring of insulin-like growth factor I in adult growth hormone deficiency: A critical appraisal
    • Gibney J, Johannsson G. Long-term monitoring of insulin-like growth factor I in adult growth hormone deficiency: a critical appraisal. Horm Res. 2004;62(Suppl 1):66-72.
    • (2004) Horm Res , vol.62 , Issue.SUPPL. 1 , pp. 66-72
    • Gibney, J.1    Johannsson, G.2
  • 30
    • 0027378414 scopus 로고
    • Growth hormone dose regimens in adult GH deficiency: Effects on biochemical growth markers and metabolic parameters
    • Moller J, Jorgensen JO, Lauersen T, et al. Growth hormone dose regimens in adult GH deficiency: effects on biochemical growth markers and metabolic parameters. Clin Endocrinol (Oxf). 1993;39:403-408.
    • (1993) Clin Endocrinol (Oxf) , vol.39 , pp. 403-408
    • Moller, J.1    Jorgensen, J.O.2    Lauersen, T.3
  • 31
    • 0024267957 scopus 로고
    • Pulsatile intravenous growth hormone (GH) infusion to hypophysectomized rats increases insulin-like growth factor I messenger ribonucleic acid in skeletal tissues more effectively than continuous GH infusion
    • Isgaard J, Carlsson L, Isaksson OG, et al. Pulsatile intravenous growth hormone (GH) infusion to hypophysectomized rats increases insulin-like growth factor I messenger ribonucleic acid in skeletal tissues more effectively than continuous GH infusion. Endocrinology. 1988;123:2605-2610.
    • (1988) Endocrinology , vol.123 , pp. 2605-2610
    • Isgaard, J.1    Carlsson, L.2    Isaksson, O.G.3
  • 32
    • 0028348279 scopus 로고
    • Diagnosis of growth-hormone deficiency in adults
    • Hoffman DM, O'Sullivan AJ, Baxter RC, et al. Diagnosis of growth-hormone deficiency in adults. Lancet. 1994;343:1064-1068.
    • (1994) Lancet , vol.343 , pp. 1064-1068
    • Hoffman, D.M.1    O'Sullivan, A.J.2    Baxter, R.C.3
  • 33
    • 0036169179 scopus 로고    scopus 로고
    • Which patients do not require a GH stimulation test for the diagnosis of adult GH deficiency?
    • Hartman ML, Crowe BJ, Biller BM, et al. Which patients do not require a GH stimulation test for the diagnosis of adult GH deficiency? J Clin Endocrinol Metab. 2002;87:477-485.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 477-485
    • Hartman, M.L.1    Crowe, B.J.2    Biller, B.M.3
  • 34
    • 0035662227 scopus 로고    scopus 로고
    • Oral estrogen antagonizes the metabolic actions of growth hormone in growth hormone-deficient women
    • Wolthers T, Hoffman DM, Nugent AG, et al. Oral estrogen antagonizes the metabolic actions of growth hormone in growth hormone-deficient women. Am J Physiol Endocrinol Metab. 2001;281:E1191-E1196.
    • (2001) Am J Physiol Endocrinol Metab , vol.281
    • Wolthers, T.1    Hoffman, D.M.2    Nugent, A.G.3
  • 35
    • 0029922124 scopus 로고    scopus 로고
    • The individual responsiveness to growth hormone (GH) treatment in GH-deficient adults is dependent on the level of GH-binding protein, body mass index, age, and gender
    • Johannsson G, Bjarnason R, Bramnert M, et al. The individual responsiveness to growth hormone (GH) treatment in GH-deficient adults is dependent on the level of GH-binding protein, body mass index, age, and gender. J Clin Endocrinol Metab. 1996;81:1575-1581.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1575-1581
    • Johannsson, G.1    Bjarnason, R.2    Bramnert, M.3
  • 36
    • 14444278299 scopus 로고    scopus 로고
    • Optimizing growth hormone replacement therapy by dose titration in hypopituitary adults
    • Drake WM, Coyte D, Camacho-Hubner C, et al. Optimizing growth hormone replacement therapy by dose titration in hypopituitary adults. J Clin Endocrinol Metab. 1998;83:3913-3919.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3913-3919
    • Drake, W.M.1    Coyte, D.2    Camacho-Hubner, C.3
  • 37
    • 0033323802 scopus 로고    scopus 로고
    • The effects of treatment and the individual responsiveness to growth hormone (GH) replacement therapy in 665 GH-deficient adults: KIMS Study Group and the KIMS International Board
    • Bengtsson BA, Abs R, Bennmarker H, et al. The effects of treatment and the individual responsiveness to growth hormone (GH) replacement therapy in 665 GH-deficient adults: KIMS Study Group and the KIMS International Board. J Clin Endocrinol Metab. 1999;84:3929-3935.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3929-3935
    • Bengtsson, B.A.1    Abs, R.2    Bennmarker, H.3
  • 38
    • 0034749231 scopus 로고    scopus 로고
    • A prospective study of 5 years of GH replacement therapy in GH-deficient adults: Sustained effects on body composition, bone mass, and metabolic indices
    • Gotherstrom G, Svensson J, Koranyi J, et al. A prospective study of 5 years of GH replacement therapy in GH-deficient adults: sustained effects on body composition, bone mass, and metabolic indices. J Clin Endocrinol Metab. 2001;86:4657-4665.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4657-4665
    • Gotherstrom, G.1    Svensson, J.2    Koranyi, J.3
  • 39
    • 0037693145 scopus 로고    scopus 로고
    • Five years of growth hormone replacement therapy in adults: Age- and gender-related changes in isometric and isokinetic muscle strength
    • Svensson J, Sunnerhagen KS, Johannsson G. Five years of growth hormone replacement therapy in adults: age- and gender-related changes in isometric and isokinetic muscle strength. J Clin Endocrinol Metab. 2003;88:2061-2069.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2061-2069
    • Svensson, J.1    Sunnerhagen, K.S.2    Johannsson, G.3
  • 40
    • 0035033682 scopus 로고    scopus 로고
    • Liver-specific IGF-1 gene deletion leads to muscle insulin insensitivity
    • Yakar S, Liu JL, Fernandez AM, et al. Liver-specific IGF-1 gene deletion leads to muscle insulin insensitivity. Diabetes. 2001;50:1110-1118.
    • (2001) Diabetes , vol.50 , pp. 1110-1118
    • Yakar, S.1    Liu, J.L.2    Fernandez, A.M.3
  • 41
    • 13044294029 scopus 로고    scopus 로고
    • Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice
    • Sjogren K, Liu JL, Blad K, et al. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice. Proc Natl Acad Sci. 1999;96:7088-7092.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 7088-7092
    • Sjogren, K.1    Liu, J.L.2    Blad, K.3
  • 42
    • 0015431771 scopus 로고
    • Age-related change in the twenty-four-hour spontaneous secretion of growth hormone
    • Finkelstein JW, Roffwarg HP, Boyar RM, et al. Age-related change in the twenty-four-hour spontaneous secretion of growth hormone. J Clin Endocrinol Metab. 1972;35:665-670.
    • (1972) J Clin Endocrinol Metab , vol.35 , pp. 665-670
    • Finkelstein, J.W.1    Roffwarg, H.P.2    Boyar, R.M.3
  • 43
    • 0022447036 scopus 로고
    • Cluster analysis: A simple, versatile, and robust algorithm for endocrine pulse detection
    • Veldhuis JD, Johnson ML. Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection. Am J Physiol. 1986;250: E486-E493.
    • (1986) Am J Physiol , vol.250
    • Veldhuis, J.D.1    Johnson, M.L.2
  • 44
    • 0020043737 scopus 로고
    • Effect of frequency of growth hormone administration on longitudinal bone growth and body weight in hypophysectomized rats
    • Jansson JO, Albertsson-Wikland K, Eden S, et al. Effect of frequency of growth hormone administration on longitudinal bone growth and body weight in hypophysectomized rats. Acta Physiol Scand. 1982;114:261-265.
    • (1982) Acta Physiol Scand , vol.114 , pp. 261-265
    • Jansson, J.O.1    Albertsson-Wikland, K.2    Eden, S.3
  • 45
    • 0021948915 scopus 로고
    • Intravenous growth hormone: Growth responses to patterned infusions in hypophysectomized rats
    • Clark RG, Jansson JO, Isaksson O, et al. Intravenous growth hormone: growth responses to patterned infusions in hypophysectomized rats. J Endocrinol. 1985;104:53-61.
    • (1985) J Endocrinol , vol.104 , pp. 53-61
    • Clark, R.G.1    Jansson, J.O.2    Isaksson, O.3
  • 46
    • 0025292432 scopus 로고
    • Pulsatile versus continuous intravenous administration of growth hormone (GH) in GH-deficient patients: Effects on circulating insulin-like growth factor-I and metabolic indices
    • Jorgensen JO, Moller N, Lauritzen T, et al. Pulsatile versus continuous intravenous administration of growth hormone (GH) in GH-deficient patients: effects on circulating insulin-like growth factor-I and metabolic indices. J Clin Endocrinol Metab. 1990;70:1616-1623.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 1616-1623
    • Jorgensen, J.O.1    Moller, N.2    Lauritzen, T.3
  • 47
    • 0002126250 scopus 로고
    • Metabolic response to growth hormone (GH) administration in GH-deficient patients: Effects on circulating insulin-like growth factor-1 and metabolic indices
    • Laursen T, Jorgensen JO, Christiansen JS. Metabolic response to growth hormone (GH) administration in GH-deficient patients: effects on circulating insulin-like growth factor-1 and metabolic indices. Endocrinol Metab. 1994;1:33-40.
    • (1994) Endocrinol Metab , vol.1 , pp. 33-40
    • Laursen, T.1    Jorgensen, J.O.2    Christiansen, J.S.3
  • 48
    • 0021355526 scopus 로고
    • The effect of small but sustained elevations in circulating growth hormone on fuel metabolism in growth hormone deficiency
    • Tamborlane WV, Genel M, Gianfredi S, et al. The effect of small but sustained elevations in circulating growth hormone on fuel metabolism in growth hormone deficiency. Pediatr Res. 1984;18:212-215.
    • (1984) Pediatr Res , vol.18 , pp. 212-215
    • Tamborlane, W.V.1    Genel, M.2    Gianfredi, S.3
  • 50
  • 51
    • 0019950213 scopus 로고
    • Colonic polyps in patients with acromegaly
    • Klein I, Parveen G, Gavaler JS, et al. Colonic polyps in patients with acromegaly. Ann Intern Med. 1982;97:27-30.
    • (1982) Ann Intern Med , vol.97 , pp. 27-30
    • Klein, I.1    Parveen, G.2    Gavaler, J.S.3
  • 52
    • 0021987088 scopus 로고
    • Gastrointestinal tumors in acromegalic patients
    • Pines A, Rozen P, Ron E, et al. Gastrointestinal tumors in acromegalic patients. Am J Gastroenterol. 1985;80:266-269.
    • (1985) Am J Gastroenterol , vol.80 , pp. 266-269
    • Pines, A.1    Rozen, P.2    Ron, E.3
  • 53
    • 0026341594 scopus 로고
    • Acromegaly and gastrointestinal cancer
    • Ron E, Gridley G, Hrubec Z, et al. Acromegaly and gastrointestinal cancer. Cancer. 1991;68:1673-1677.
    • (1991) Cancer , vol.68 , pp. 1673-1677
    • Ron, E.1    Gridley, G.2    Hrubec, Z.3
  • 54
    • 0025906737 scopus 로고
    • Clinical review 18: Are patients with acromegaly at increased risk for neoplasia?
    • Ezzat S, Melmed S. Clinical review 18: are patients with acromegaly at increased risk for neoplasia? J Clin Endocrinol Metab. 1991;72:245-249.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 245-249
    • Ezzat, S.1    Melmed, S.2
  • 55
    • 0034928043 scopus 로고    scopus 로고
    • Clinical perspective: Acromegaly and cancer - a problem
    • Jenkins PJ, Besser M. Clinical perspective: acromegaly and cancer - a problem. J Clin Endocrinol Metab. 2001;86:2935-2941.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2935-2941
    • Jenkins, P.J.1    Besser, M.2
  • 56
    • 0033977954 scopus 로고    scopus 로고
    • Modern approaches to treating acromegaly
    • Turner HE, Wass JA. Modern approaches to treating acromegaly. Q J Med. 2000;93:1-6.
    • (2000) Q J Med , vol.93 , pp. 1-6
    • Turner, H.E.1    Wass, J.A.2
  • 57
    • 33750080457 scopus 로고    scopus 로고
    • Cancers associated with acromegaly
    • Jenkins PJ. Cancers associated with acromegaly. Neuroendocrinology. 2006;83:218-223.
    • (2006) Neuroendocrinology , vol.83 , pp. 218-223
    • Jenkins, P.J.1
  • 58
    • 0022526845 scopus 로고
    • Osteosarcoma of the mandible arising in fibrous dysplasia: A case report
    • Present D, Bertoni F, Enneking WF. Osteosarcoma of the mandible arising in fibrous dysplasia: a case report. Clin Orthop Relat Res. 1986;204:238-244.
    • (1986) Clin Orthop Relat Res , vol.204 , pp. 238-244
    • Present, D.1    Bertoni, F.2    Enneking, W.F.3
  • 59
    • 0024669221 scopus 로고
    • Fibrous dysplasia of the skull with acromegaly and sarcomatous transformation: Two cases with a review of the literature
    • Mortensen A, Bojsen-Moller M, Rasmussen P. Fibrous dysplasia of the skull with acromegaly and sarcomatous transformation: two cases with a review of the literature. J Neurooncol. 1989;7:25-29.
    • (1989) J Neurooncol , vol.7 , pp. 25-29
    • Mortensen, A.1    Bojsen-Moller, M.2    Rasmussen, P.3
  • 60
    • 33846982969 scopus 로고    scopus 로고
    • Osteosarcoma and acromegaly: A case report and review of the literature
    • Lima GA, Gomes EM, Nunes RC, et al. Osteosarcoma and acromegaly: a case report and review of the literature. J Endocrinol Invest. 2006;29:1006-1011.
    • (2006) J Endocrinol Invest , vol.29 , pp. 1006-1011
    • Lima, G.A.1    Gomes, E.M.2    Nunes, R.C.3
  • 61
    • 0025333249 scopus 로고
    • Premature mortality due to cardiovascular disease in hypopituitarism
    • Rosen T, Bengtsson BA. Premature mortality due to cardiovascular disease in hypopituitarism. Lancet. 1990;336:285-288.
    • (1990) Lancet , vol.336 , pp. 285-288
    • Rosen, T.1    Bengtsson, B.A.2
  • 62
    • 3242712491 scopus 로고    scopus 로고
    • The incidence of malignant disease and cardiovascular morbidity in hypopituitary patients with or without growth hormone replacement therapy
    • Svensson J, Bengtsson B, Rosen T, et al. The incidence of malignant disease and cardiovascular morbidity in hypopituitary patients with or without growth hormone replacement therapy. J Clin Endocrinol Metab. 2004;89:3306-3312.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3306-3312
    • Svensson, J.1    Bengtsson, B.2    Rosen, T.3
  • 63
    • 0026767794 scopus 로고
    • High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice
    • Tornell J, Carlsson B, Pohjanen P, et al. High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice. J Steroid Biochem Mol Biol. 1992;43:237-242.
    • (1992) J Steroid Biochem Mol Biol , vol.43 , pp. 237-242
    • Tornell, J.1    Carlsson, B.2    Pohjanen, P.3
  • 64
    • 0021869257 scopus 로고
    • Elevated growth hormone levels in sera from breast cancer patients
    • Emerman JT, Leahy M, Gout PW, et al. Elevated growth hormone levels in sera from breast cancer patients. Horm Metab Res. 1985;17:421-424.
    • (1985) Horm Metab Res , vol.17 , pp. 421-424
    • Emerman, J.T.1    Leahy, M.2    Gout, P.W.3
  • 65
    • 4444360468 scopus 로고    scopus 로고
    • Increased fasting serum levels of growth hormone and gastrin in patients with gastric and large bowel cancer
    • Triantafillidis JK, Merikas E, Govosdis V, et al. Increased fasting serum levels of growth hormone and gastrin in patients with gastric and large bowel cancer. Hepatogastroenterology. 2003;50(Suppl 2):cclvi-cclx
    • (2003) Hepatogastroenterology , vol.50 , Issue.SUPPL. 2
    • Triantafillidis, J.K.1    Merikas, E.2    Govosdis, V.3
  • 66
    • 0033065792 scopus 로고    scopus 로고
    • Decreased serum levels of insulin-like growth factor (IGF)-I in patients with lung cancer: Temporal relationship with growth hormone (GH) levels
    • Mazzoccoli G, Giuliani A, Bianco G, et al. Decreased serum levels of insulin-like growth factor (IGF)-I in patients with lung cancer: temporal relationship with growth hormone (GH) levels. Anticancer Res. 1999;19:1397-1399.
    • (1999) Anticancer Res , vol.19 , pp. 1397-1399
    • Mazzoccoli, G.1    Giuliani, A.2    Bianco, G.3
  • 67
    • 22544461679 scopus 로고    scopus 로고
    • The role of the growth hormone/insulin-like growth factor axis in tumor growth and progression: Lessons from animal models
    • Yakar S, Leroith D, Brodt P. The role of the growth hormone/insulin-like growth factor axis in tumor growth and progression: lessons from animal models. Cytokine Growth Factor Rev. 2005;16:407-420.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 407-420
    • Yakar, S.1    Leroith, D.2    Brodt, P.3
  • 69
    • 0034453098 scopus 로고    scopus 로고
    • The effects of insulin-like growth factors on tumorigenesis and neoplastic growth
    • Khandwala HM, McCutcheon IE, Flyvbjerg A, et al. The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev. 2000;21:215-244.
    • (2000) Endocr Rev , vol.21 , pp. 215-244
    • Khandwala, H.M.1    McCutcheon, I.E.2    Flyvbjerg, A.3
  • 70
    • 0026014578 scopus 로고
    • Prolactin and growth hormone levels in premenopausal women with breast cancer and healthy women with a strong family history of breast cancer
    • Love RR, Rose DR, Surawicz TS, et al. Prolactin and growth hormone levels in premenopausal women with breast cancer and healthy women with a strong family history of breast cancer. Cancer. 1991;68:1401-1405.
    • (1991) Cancer , vol.68 , pp. 1401-1405
    • Love, R.R.1    Rose, D.R.2    Surawicz, T.S.3
  • 71
    • 20344380164 scopus 로고    scopus 로고
    • Basal growth hormone concentrations in blood and the risk for prostate cancer: A case-control study
    • Fuhrman B, Barba M, Schunemann HJ, et al. Basal growth hormone concentrations in blood and the risk for prostate cancer: a case-control study. Prostate. 2005;64:109-115.
    • (2005) Prostate , vol.64 , pp. 109-115
    • Fuhrman, B.1    Barba, M.2    Schunemann, H.J.3
  • 72
    • 29144508886 scopus 로고    scopus 로고
    • Association of polymorphisms and haplotypes in the human growth hormone 1 (GH1) gene with breast cancer
    • Wagner K, Hemminki K, Israelsson E, et al. Association of polymorphisms and haplotypes in the human growth hormone 1 (GH1) gene with breast cancer. Endocr Relat Cancer. 2005;12:917-928.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 917-928
    • Wagner, K.1    Hemminki, K.2    Israelsson, E.3
  • 73
    • 0037240296 scopus 로고    scopus 로고
    • Human growth hormone 1 (GH1) gene expression: Complex haplotype-dependent influence of polymorphic variation in the proximal promoter and locus control region
    • Horan M, Millar DS, Hedderich J, et al. Human growth hormone 1 (GH1) gene expression: complex haplotype-dependent influence of polymorphic variation in the proximal promoter and locus control region. Hum Mutat. 2003;21:408-423.
    • (2003) Hum Mutat , vol.21 , pp. 408-423
    • Horan, M.1    Millar, D.S.2    Hedderich, J.3
  • 74
    • 0037139518 scopus 로고    scopus 로고
    • Association of a common polymorphism in the human GH1 gene with colorectal neoplasia
    • Le Marchand L, Donlon T, Seifried A, et al. Association of a common polymorphism in the human GH1 gene with colorectal neoplasia. J Natl Cancer Inst. 2002;94:454-460.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 454-460
    • Le Marchand, L.1    Donlon, T.2    Seifried, A.3
  • 75
    • 3042785734 scopus 로고    scopus 로고
    • Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma
    • Ren Z, Cai Q, Shu XO, et al. Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma. Cancer. 2004;101:251-257.
    • (2004) Cancer , vol.101 , pp. 251-257
    • Ren, Z.1    Cai, Q.2    Shu, X.O.3
  • 76
    • 33646363047 scopus 로고    scopus 로고
    • Polymorphisms in the growth hormone receptor: A case-control study in breast cancer
    • Wagner K, Hemminki K, Grzybowska E, et al. Polymorphisms in the growth hormone receptor: a case-control study in breast cancer. Int J Cancer. 2006;118:2903-2906.
    • (2006) Int J Cancer , vol.118 , pp. 2903-2906
    • Wagner, K.1    Hemminki, K.2    Grzybowska, E.3
  • 77
    • 33744785962 scopus 로고    scopus 로고
    • Variants in the GH-IGF axis confer susceptibility to lung cancer
    • Rudd MF, Webb EL, Matakidou A, et al. Variants in the GH-IGF axis confer susceptibility to lung cancer. Genome Res. 2006;16:693-701.
    • (2006) Genome Res , vol.16 , pp. 693-701
    • Rudd, M.F.1    Webb, E.L.2    Matakidou, A.3
  • 78
    • 26444620298 scopus 로고    scopus 로고
    • Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: Results from the European prospective investigation into cancer and nutrition study
    • Canzian F, McKay JD, Cleveland RJ, et al. Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study. Cancer Epidemiol Biomarkers Prev. 2005;14:2316-2325.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 2316-2325
    • Canzian, F.1    McKay, J.D.2    Cleveland, R.J.3
  • 79
    • 33747892640 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in GH1 release and their association with breast cancer risk
    • Wagner K, Hemminki K, Grzybowska E, et al. Polymorphisms in genes involved in GH1 release and their association with breast cancer risk. Carcinogenesis. 2006;27:1867-1875.
    • (2006) Carcinogenesis , vol.27 , pp. 1867-1875
    • Wagner, K.1    Hemminki, K.2    Grzybowska, E.3
  • 80
    • 0029020253 scopus 로고
    • Relationship of growth hormone deficiency and leukemia
    • Rapaport R, Oberfield SE, Robison L, et al. Relationship of growth hormone deficiency and leukemia. J Pediatr. 1995;126:759-761.
    • (1995) J Pediatr , vol.126 , pp. 759-761
    • Rapaport, R.1    Oberfield, S.E.2    Robison, L.3
  • 81
    • 0030659547 scopus 로고    scopus 로고
    • Risk of leukemia in children treated with human growth hormone: Review and reanalysis
    • Allen DB, Rundle AC, Graves DA, et al. Risk of leukemia in children treated with human growth hormone: review and reanalysis. J Pediatr. 1997;131:S32-S36.
    • (1997) J Pediatr , vol.131
    • Allen, D.B.1    Rundle, A.C.2    Graves, D.A.3
  • 82
    • 0023943180 scopus 로고
    • Leukemia in patients treated with growth hormone
    • Watanabe S, Tsuenematsu Y, Fujimoto J, et al. Leukemia in patients treated with growth hormone. Lancet. 1988;1(8595):1159-1160.
    • (1988) Lancet , vol.1 , Issue.8595 , pp. 1159-1160
    • Watanabe, S.1    Tsuenematsu, Y.2    Fujimoto, J.3
  • 83
    • 0033304591 scopus 로고    scopus 로고
    • Recent status in the occurrence of leukemia in growth hormone-treated patients in Japan: GH Treatment Study Committee of the Foundation for Growth Science, Japan
    • Nishi Y, Tanaka T, Takano K, et al. Recent status in the occurrence of leukemia in growth hormone-treated patients in Japan: GH Treatment Study Committee of the Foundation for Growth Science, Japan. J Clin Endocrinol Metab. 1999;84:1961-1965.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1961-1965
    • Nishi, Y.1    Tanaka, T.2    Takano, K.3
  • 84
    • 0037183320 scopus 로고    scopus 로고
    • Risk of cancer in patients treated with human pituitary growth hormone in the UK, 1959-85: A cohort study
    • Swerdlow AJ, Higgins CD, Adlard P, et al. Risk of cancer in patients treated with human pituitary growth hormone in the UK, 1959-85: a cohort study. Lancet. 2002;360:273-277.
    • (2002) Lancet , vol.360 , pp. 273-277
    • Swerdlow, A.J.1    Higgins, C.D.2    Adlard, P.3
  • 85
    • 33845953901 scopus 로고    scopus 로고
    • Neoplasms reported during growth hormone replacement in KIMS
    • Presented at: June 20, Philadelphia, PA. Abstract
    • Wilton P, Mattsson A, Abs R, et al. Neoplasms reported during growth hormone replacement in KIMS. Presented at: The Endocrine Society's 85th Annual Meeting; June 20, 2003; Philadelphia, PA. Abstract OR20-6.
    • (2003) The Endocrine Society's 85th Annual Meeting
    • Wilton, P.1    Mattsson, A.2    Abs, R.3
  • 86
    • 15444340668 scopus 로고    scopus 로고
    • Increased incidence of neoplasia in patients with pituitary adenomas: The Pituitary Study Group
    • Popovic V, Damjanovic S, Micic D, et al. Increased incidence of neoplasia in patients with pituitary adenomas: the Pituitary Study Group. Clin Endocrinol (Oxf). 1998;49:441-445.
    • (1998) Clin Endocrinol (Oxf) , vol.49 , pp. 441-445
    • Popovic, V.1    Damjanovic, S.2    Micic, D.3
  • 87
    • 0034457364 scopus 로고    scopus 로고
    • Pituitary adenomas in Sweden between 1958 and 1991: Incidence, survival, and mortality
    • Nilsson B, Gustavasson-Kadaka E, Bengtsson BA, et al. Pituitary adenomas in Sweden between 1958 and 1991: incidence, survival, and mortality. J Clin Endocrinol Metab. 2000;85:1420-1425.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1420-1425
    • Nilsson, B.1    Gustavasson-Kadaka, E.2    Bengtsson, B.A.3
  • 88
    • 17744387904 scopus 로고    scopus 로고
    • Growth hormone treatment of children with brain tumors and risk of tumor recurrence
    • Swerdlow AJ, Reddingius RE, Higgins CD, et al. Growth hormone treatment of children with brain tumors and risk of tumor recurrence. J Clin Endocrinol Metab. 2000;85:4444-4449.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4444-4449
    • Swerdlow, A.J.1    Reddingius, R.E.2    Higgins, C.D.3
  • 89
    • 0035863507 scopus 로고    scopus 로고
    • Growth hormone replacement therapy in children with medulloblastoma: Use and effect on tumor control
    • Packer RJ, Boyett JM, Janss AJ, et al. Growth hormone replacement therapy in children with medulloblastoma: use and effect on tumor control. J Clin Oncol. 2001;19:480-487.
    • (2001) J Clin Oncol , vol.19 , pp. 480-487
    • Packer, R.J.1    Boyett, J.M.2    Janss, A.J.3
  • 90
    • 0036312704 scopus 로고    scopus 로고
    • Risk of disease recurrence and second neoplasms in survivors of childhood cancer treated with growth hormone: A report from the Childhood Cancer Survivor Study
    • Sklar CA, Mertens AC, Mitby P, et al. Risk of disease recurrence and second neoplasms in survivors of childhood cancer treated with growth hormone: a report from the Childhood Cancer Survivor Study. J Clin Endocrinol Metab. 2002;87:3136-3141.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3136-3141
    • Sklar, C.A.1    Mertens, A.C.2    Mitby, P.3
  • 91
    • 0036645443 scopus 로고    scopus 로고
    • Outcomes of growth hormone replacement therapy in survivors of childhood acute lymphoblastic leukemia
    • Leung W, Rose SR, Zhou Y, et al. Outcomes of growth hormone replacement therapy in survivors of childhood acute lymphoblastic leukemia. J Clin Oncol. 2002;20:2959-2964.
    • (2002) J Clin Oncol , vol.20 , pp. 2959-2964
    • Leung, W.1    Rose, S.R.2    Zhou, Y.3
  • 92
    • 0035170784 scopus 로고    scopus 로고
    • Hypothalamo-pituitary surveillance imaging in hypopituitary patients receiving long-term GH replacement therapy
    • Frajese G, Drake WM, Loureiro RA, et al. Hypothalamo-pituitary surveillance imaging in hypopituitary patients receiving long-term GH replacement therapy. J Clin Endocrinol Metab. 2001;86:5172-5175.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5172-5175
    • Frajese, G.1    Drake, W.M.2    Loureiro, R.A.3
  • 93
    • 0036306366 scopus 로고    scopus 로고
    • Does GH replacement therapy in adult GH-deficient patients result in recurrence or increase in size of pituitary tumours?
    • Hatrick AG, Boghalo P, Bingham JB, et al. Does GH replacement therapy in adult GH-deficient patients result in recurrence or increase in size of pituitary tumours? Eur J Endocrinol. 2002;146:807-811.
    • (2002) Eur J Endocrinol , vol.146 , pp. 807-811
    • Hatrick, A.G.1    Boghalo, P.2    Bingham, J.B.3
  • 94
    • 8044255242 scopus 로고    scopus 로고
    • Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment: Adult Growth Hormone Deficiency Study Group
    • Attanasio AF, Lamberts SW, Matranga AM, et al. Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment: Adult Growth Hormone Deficiency Study Group. J Clin Endocrinol Metab. 1997;82:82-88.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 82-88
    • Attanasio, A.F.1    Lamberts, S.W.2    Matranga, A.M.3
  • 95
    • 14444282422 scopus 로고    scopus 로고
    • The Australian Multicenter Trial of Growth Hormone (GH) Treatment in GH-Deficient Adults
    • Cuneo RC, Judd S, Wallace JD, et al. The Australian Multicenter Trial of Growth Hormone (GH) Treatment in GH-Deficient Adults. J Clin Endocrinol Metab. 1998;83:107-116.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 107-116
    • Cuneo, R.C.1    Judd, S.2    Wallace, J.D.3
  • 96
    • 0036488604 scopus 로고    scopus 로고
    • Second cancers in survivors of childhood cancer
    • Bhatia S, Sklar C. Second cancers in survivors of childhood cancer. Nat Rev Cancer. 2002;2:124-132.
    • (2002) Nat Rev Cancer , vol.2 , pp. 124-132
    • Bhatia, S.1    Sklar, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.