Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane

Apoptosis

Volumn 13, Issue 3, 2008, Pages 423-436

  Šímová, Šárka ^a   Klíma, Martin ^a   Cermak, Lukas ^a   Šourková, Vladimíra ^a   Anděra, Ladislav ^a  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

Author keywords

Apoptosis; Interaction; Receptor; Signaling; Trafficking; TRAIL

Indexed keywords

ADAPTOR PROTEIN; AMINO ACID; ARAP1 PROTEIN; ARF PROTEIN; DEATH RECEPTOR 4; DEATH RECEPTOR 5; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE; CELL SURFACE; CELL TRANSPORT; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOSOME; GENETIC TRANSFECTION; GOLGI COMPLEX; HELA CELL; HUMAN; HUMAN CELL; INTRACELLULAR MEMBRANE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; TUMOR CELL LINE; TWO HYBRID SYSTEM;

EID: 40049092624     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-007-0171-8     Document Type: Article

References (52)

1. 1. SR Wiley K Schooley PJ Smolak 1995 Identification and characterization of a new member of the TNF family that induces apoptosis Immunity 3 673 682 8777713 10.1016/1074-7613(95)90057-8 1:CAS:528:DyaK28XhtF2iug%3D%3D Wiley SR, Schooley K, Smolak PJ et al (1995) Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3:673–682
2. 2. H Walczak PH Krammer 2000 The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems Exp Cell Res 256 58 66 10739652 10.1006/excr.2000.4840 1:CAS:528:DC%2BD3cXitVajsb4%3D Walczak H, Krammer PH (2000) The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 256:58–66
3. 3. A Ashkenazi RC Pai S Fong 1999 Safety and antitumor activity of recombinant soluble Apo2 ligand J Clin Invest 104 155 162 10411544 10.1172/JCI6926 1:CAS:528:DyaK1MXkslSmsbw%3D Ashkenazi A, Pai RC, Fong S et al (1999) Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 104:155–162
4. 4. H Walczak RE Miller K Ariail 1999 Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo Nat Med 5 157 163 9930862 10.1038/5517 1:CAS:528:DyaK1MXntlSrug%3D%3D Walczak H, Miller RE, Ariail K et al (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5:157–163
5. 5. G Pan K O’Rourke AM Chinnaiyan 1997 The receptor for the cytotoxic ligand TRAIL Science 276 111 113 9082980 10.1126/science.276.5309.111 1:CAS:528:DyaK2sXitl2jsL4%3D Pan G, O’Rourke K, Chinnaiyan AM et al (1997) The receptor for the cytotoxic ligand TRAIL. Science 276:111–113
6. 6. H Walczak MA Degli-Esposti RS Johnson 1997 TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL Embo J 16 5386 5397 9311998 10.1093/emboj/16.17.5386 1:CAS:528:DyaK2sXmsVGlsLo%3D Walczak H, Degli-Esposti MA, Johnson RS et al (1997) TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. Embo J 16:5386–5397
7. 7. MA Degli-Esposti PJ Smolak H Walczak 1997 Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family J Exp Med 186 1165 1170 9314565 10.1084/jem.186.7.1165 1:CAS:528:DyaK2sXmsFaqs70%3D Degli-Esposti MA, Smolak PJ, Walczak H et al (1997) Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J Exp Med 186:1165–1170
8. 8. MA Degli-Esposti WC Dougall PJ Smolak 1997 The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain Immunity 7 813 820 9430226 10.1016/S1074-7613(00)80399-4 1:CAS:528:DyaK1cXjsFWgtQ%3D%3D Degli-Esposti MA, Dougall WC, Smolak PJ et al (1997) The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 7:813–820
9. 9. JG Emery P McDonnell MB Burke 1998 Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL J Biol Chem 273 14363 14367 9603945 10.1074/jbc.273.23.14363 1:CAS:528:DyaK1cXjs1Oru70%3D Emery JG, McDonnell P, Burke MB et al (1998) Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 273:14363–14367
10. 10. BR Chaudhari RF Murphy DK Agrawal 2006 Following the TRAIL to apoptosis Immunol Res 35 249 262 17172650 10.1385/IR:35:3:249 1:CAS:528:DC%2BD28Xht1OjsbnF Chaudhari BR, Murphy RF, Agrawal DK (2006) Following the TRAIL to apoptosis. Immunol Res 35:249–262
11. 11. LA Tartaglia TM Ayres GH Wong DV Goeddel 1993 A novel domain within the 55 kd TNF receptor signals cell death Cell 74 845 853 8397073 10.1016/0092-8674(93)90464-2 1:CAS:528:DyaK2cXhvV2gsrc%3D Tartaglia LA, Ayres TM, Wong GH, Goeddel DV (1993) A novel domain within the 55 kd TNF receptor signals cell death. Cell 74:845–853
12. 12. FC Kischkel S Hellbardt I Behrmann 1995 Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor Embo J 14 5579 5588 8521815 1:CAS:528:DyaK2MXpslamtr4%3D Kischkel FC, Hellbardt S, Behrmann I et al (1995) Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. Embo J 14:5579–5588
13. 13. MR Sprick MA Weigand E Rieser 2000 FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 Immunity 12 599 609 10894160 10.1016/S1074-7613(00)80211-3 1:CAS:528:DC%2BD3cXkslagtb8%3D Sprick MR, Weigand MA, Rieser E et al (2000) FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12:599–609
14. 14. GS Salvesen VM Dixit 1999 Caspase activation: the induced-proximity model Proc Natl Acad Sci USA 96 10964 10967 10500109 10.1073/pnas.96.20.10964 1:CAS:528:DyaK1MXmvVCnt7k%3D Salvesen GS, Dixit VM (1999) Caspase activation: the induced-proximity model. Proc Natl Acad Sci USA 96:10964–10967
15. 15. BC Barnhart EC Alappat ME Peter 2003 The CD95 type I/type II model Semin Immunol 15 185 193 14563117 10.1016/S1044-5323(03)00031-9 1:CAS:528:DC%2BD3sXmsl2rtb8%3D Barnhart BC, Alappat EC, Peter ME (2003) The CD95 type I/type II model. Semin Immunol 15:185–193
16. 16. X Luo I Budihardjo H Zou 1998 Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors Cell 94 481 490 9727491 10.1016/S0092-8674(00)81589-5 1:CAS:528:DyaK1cXlslOrsbw%3D Luo X, Budihardjo I, Zou H et al (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481–490
17. 17. BB Aggarwal U Bhardwaj Y Takada 2004 Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors Vitam Horm 67 453 483 15110190 1:CAS:528:DC%2BD2cXltlKgtb8%3D Aggarwal BB, Bhardwaj U, Takada Y (2004) Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors. Vitam Horm 67:453–483
18. 18. FC Kimberley GR Screaton 2004 Following a TRAIL: update on a ligand and its five receptors Cell Res 14 359 372 15538968 10.1038/sj.cr.7290236 1:CAS:528:DC%2BD2MXhsFekt7g%3D Kimberley FC, Screaton GR (2004) Following a TRAIL: update on a ligand and its five receptors. Cell Res 14:359–372
19. 19. XD Zhang AV Franco T Nguyen 2000 Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells J Immunol 164 3961 3970 10754286 1:CAS:528:DC%2BD3cXis1Wlur4%3D Zhang XD, Franco AV, Nguyen T et al (2000) Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells. J Immunol 164:3961–3970
20. 20. M Bennett K Macdonald SW Chan 1998 Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis Science 282 290 293 9765154 10.1126/science.282.5387.290 1:CAS:528:DyaK1cXmsF2ju70%3D Bennett M, Macdonald K, Chan SW et al (1998) Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis. Science 282:290–293
21. 21. SJ Jones EC Ledgerwood JB Prins 1999 TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1 J Immunol 162 1042 1048 9916731 1:CAS:528:DyaK1MXovFyisg%3D%3D Jones SJ, Ledgerwood EC, Prins JB et al (1999) TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1. J Immunol 162:1042–1048
22. 22. H Storey A Stewart P Vandenabeele JP Luzio 2002 The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail Biochem J 366 15 22 11985495 1:CAS:528:DC%2BD3sXptFOhsbk%3D Storey H, Stewart A, Vandenabeele P, Luzio JP (2002) The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail. Biochem J 366:15–22
23. 23. Z Nie DS Hirsch R Luo 2006 A BAR domain in the N terminus of the Arf GAP ASAP1 affects membrane structure and trafficking of epidermal growth factor receptor Curr Biol 16 130 139 16431365 10.1016/j.cub.2005.11.069 1:CAS:528:DC%2BD28Xosl2msw%3D%3D Nie Z, Hirsch DS, Luo R et al (2006) A BAR domain in the N terminus of the Arf GAP ASAP1 affects membrane structure and trafficking of epidermal growth factor receptor. Curr Biol 16:130–139
24. 24. Randazzo PA, Nie Z, Miura K, Hsu VW (2000) Molecular aspects of the cellular activities of ADP-ribosylation factors. Sci STKE 2000:RE1
25. 25. PA Randazzo DS Hirsch 2004 Arf GAPs: multifunctional proteins that regulate membrane traffic and actin remodelling Cell Signal 16 401 413 14709330 10.1016/j.cellsig.2003.09.012 1:CAS:528:DC%2BD2cXptVGr Randazzo PA, Hirsch DS (2004) Arf GAPs: multifunctional proteins that regulate membrane traffic and actin remodelling. Cell Signal 16:401–413
26. 26. J Dai J Li E Bos 2004 ACAP1 promotes endocytic recycling by recognizing recycling sorting signals Dev Cell 7 771 776 15525538 10.1016/j.devcel.2004.10.002 1:CAS:528:DC%2BD2cXhtVWgsLbE Dai J, Li J, Bos E et al (2004) ACAP1 promotes endocytic recycling by recognizing recycling sorting signals. Dev Cell 7:771–776
27. 27. I Majoul M Straub SW Hell 2001 KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET Dev Cell 1 139 153 11703931 10.1016/S1534-5807(01)00004-1 1:CAS:528:DC%2BD3MXltlarur0%3D Majoul I, Straub M, Hell SW et al (2001) KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET. Dev Cell 1:139–153
28. 28. K Miura KM Jacques S Stauffer 2002 ARAP1: a point of convergence for Arf and Rho signaling Mol Cell 9 109 119 11804590 10.1016/S1097-2765(02)00428-8 1:CAS:528:DC%2BD38XhtVyjsL0%3D Miura K, Jacques KM, Stauffer S et al (2002) ARAP1: a point of convergence for Arf and Rho signaling. Mol Cell 9:109–119
29. 29. M Plasilova J Zivny J Jelinek 2002 TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors Leukemia 16 67 73 11840265 10.1038/sj.leu.2402338 1:CAS:528:DC%2BD38Xht1yrsrs%3D Plasilova M, Zivny J, Jelinek J et al (2002) TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors. Leukemia 16:67–73
30. 30. D Matsuda Y Nakayama S Horimoto 2006 Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress Exp Cell Res 312 1205 1217 16527271 10.1016/j.yexcr.2006.02.003 1:CAS:528:DC%2BD28XivV2rtLg%3D Matsuda D, Nakayama Y, Horimoto S et al (2006) Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress. Exp Cell Res 312:1205–1217
31. 31. U Schaefer O Voloshanenko D Willen H Walczak 2007 TRAIL: a multifunctional cytokine Front Biosci 12 3813 3824 17485341 10.2741/2354 1:CAS:528:DC%2BD2sXms1Kmu7w%3D Schaefer U, Voloshanenko O, Willen D, Walczak H (2007) TRAIL: a multifunctional cytokine. Front Biosci 12:3813–3824
32. 32. A Thorburn 2007 Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway signaling J Thorac Oncol 2 461 465 17545839 10.1097/JTO.0b013e31805fea64 Thorburn A (2007) Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway signaling. J Thorac Oncol 2:461–465
33. 33. Y Lin A Devin A Cook 2000 The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase Mol Cell Biol 20 6638 6645 10958661 10.1128/MCB.20.18.6638-6645.2000 1:CAS:528:DC%2BD3cXmsVamsr4%3D Lin Y, Devin A, Cook A et al (2000) The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase. Mol Cell Biol 20:6638–6645
34. 34. O Meurette A Rebillard L Huc 2007 TRAIL induces receptor-interacting protein 1-dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions Cancer Res 67 218 226 17210702 10.1158/0008-5472.CAN-06-1610 1:CAS:528:DC%2BD2sXisFSnsg%3D%3D Meurette O, Rebillard A, Huc L et al (2007) TRAIL induces receptor-interacting protein 1-dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions. Cancer Res 67:218–226
35. 35. N Mulherkar KV Prasad BS Prabhakar 2007 MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells J Biol Chem 282 11715 11721 17314102 10.1074/jbc.M701085200 1:CAS:528:DC%2BD2sXktFemurg%3D Mulherkar N, Prasad KV, Prabhakar BS (2007) MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells. J Biol Chem 282:11715–11721
36. 36. M Ramaswamy EV Efimova O Martinez 2004 IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC Oncogene 23 6083 6094 15208670 10.1038/sj.onc.1207804 1:CAS:528:DC%2BD2cXmsVKltrY%3D Ramaswamy M, Efimova EV, Martinez O et al (2004) IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC. Oncogene 23:6083–6094
37. 37. TJ Brett LM Traub DH Fremont 2002 Accessory protein recruitment motifs in clathrin-mediated endocytosis Structure 10 797 809 12057195 10.1016/S0969-2126(02)00784-0 1:CAS:528:DC%2BD38XksFOisr8%3D Brett TJ, Traub LM, Fremont DH (2002) Accessory protein recruitment motifs in clathrin-mediated endocytosis. Structure 10:797–809
38. 38. B Ritter AY Denisov J Philie 2007 The NECAP PHear domain increases clathrin accessory protein binding potential Embo J 26 4066 4077 17762867 10.1038/sj.emboj.7601836 1:CAS:528:DC%2BD2sXhtVKiu77J Ritter B, Denisov AY, Philie J et al (2007) The NECAP PHear domain increases clathrin accessory protein binding potential. Embo J 26:4066–4077
39. 39. LR Thomas RL Johnson JC Reed A Thorburn 2004 The C-terminal tails of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas receptors have opposing functions in Fas-associated death domain (FADD) recruitment and can regulate agonist-specific mechanisms of receptor activation J Biol Chem 279 52479 52486 15452120 10.1074/jbc.M409578200 1:CAS:528:DC%2BD2cXhtVCkurzE Thomas LR, Johnson RL, Reed JC, Thorburn A (2004) The C-terminal tails of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas receptors have opposing functions in Fas-associated death domain (FADD) recruitment and can regulate agonist-specific mechanisms of receptor activation. J Biol Chem 279:52479–52486
40. 40. S Krugmann KE Anderson SH Ridley 2002 Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices Mol Cell 9 95 108 11804589 10.1016/S1097-2765(02)00434-3 1:CAS:528:DC%2BD38XhtVyjsLw%3D Krugmann S, Anderson KE, Ridley SH et al (2002) Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. Mol Cell 9:95–108
41. 41. JI Elliott A Surprenant FM Marelli-Berg 2005 Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes Nat Cell Biol 7 808 816 16025105 10.1038/ncb1279 1:CAS:528:DC%2BD2MXmvVClur4%3D Elliott JI, Surprenant A, Marelli-Berg FM et al (2005) Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes. Nat Cell Biol 7:808–816
42. 42. D Smrz L Draberova P Draber 2007 Non-apoptotic phosphatidylserine externalization induced by engagement of glycosylphosphatidylinositol-anchored proteins J Biol Chem 282 10487 10497 17284440 10.1074/jbc.M611090200 1:CAS:528:DC%2BD2sXjs1Siu74%3D Smrz D, Draberova L, Draber P (2007) Non-apoptotic phosphatidylserine externalization induced by engagement of glycosylphosphatidylinositol-anchored proteins. J Biol Chem 282:10487–10497
43. 43. TTI Stacey Z Nie A Stewart 2004 ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner J Cell Sci 117 6071 6084 10.1242/jcs.01526 1:CAS:528:DC%2BD2MXnvFansA%3D%3D Stacey TTI, Nie Z, Stewart A et al (2004) ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner. J Cell Sci 117:6071–6084
44. 44. S Krugmann S Andrews L Stephens PT Hawkins 2006 ARAP3 is essential for formation of lamellipodia after growth factor stimulation J Cell Sci 119 425 432 16418224 10.1242/jcs.02755 1:CAS:528:DC%2BD28Xit1Klsbs%3D Krugmann S, Andrews S, Stephens L, Hawkins PT (2006) ARAP3 is essential for formation of lamellipodia after growth factor stimulation. J Cell Sci 119:425–432
45. 45. HY Yoon K Miura EJ Cuthbert 2006 ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP J Cell Sci 119 4650 4666 17077126 10.1242/jcs.03237 1:CAS:528:DC%2BD2sXkt1Sj Yoon HY, Miura K, Cuthbert EJ et al (2006) ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP. J Cell Sci 119:4650–4666
46. 46. K Kowanetz K Husnjak D Holler 2004 CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors Mol Biol Cell 15 3155 3166 15090612 10.1091/mbc.E03-09-0683 1:CAS:528:DC%2BD2cXlslWns7Y%3D Kowanetz K, Husnjak K, Holler D et al (2004) CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors. Mol Biol Cell 15:3155–3166
47. 47. Z Nie J Fei RT Premont PA Randazzo 2005 The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3 J Cell Sci 118 3555 3566 16079295 10.1242/jcs.02486 1:CAS:528:DC%2BD2MXpvFKmtLk%3D Nie Z, Fei J, Premont RT, Randazzo PA (2005) The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3. J Cell Sci 118:3555–3566
48. 48. Z Jin ER McDonald 3rd DT Dicker WS El-Deiry 2004 Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis J Biol Chem 279 35829 35839 15155747 10.1074/jbc.M405538200 1:CAS:528:DC%2BD2cXmsl2ht74%3D Jin Z, McDonald ER 3rd, Dicker DT, El-Deiry WS (2004) Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis. J Biol Chem 279:35829–35839
49. 49. YG Ren KW Wagner DA Knee 2004 Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle Mol Biol Cell 15 5064 5074 15356269 10.1091/mbc.E04-03-0184 1:CAS:528:DC%2BD2cXpslKnsb4%3D Ren YG, Wagner KW, Knee DA et al (2004) Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle. Mol Biol Cell 15:5064–5074
50. 50. VN Ivanov Z Ronai TK Hei 2006 Opposite roles of FAP-1 and dynamin in the regulation of Fas (CD95) translocation to the cell surface and susceptibility to Fas ligand-mediated apoptosis J Biol Chem 281 1840 1852 16306044 10.1074/jbc.M509866200 1:CAS:528:DC%2BD28XksFOrtQ%3D%3D Ivanov VN, Ronai Z, Hei TK (2006) Opposite roles of FAP-1 and dynamin in the regulation of Fas (CD95) translocation to the cell surface and susceptibility to Fas ligand-mediated apoptosis. J Biol Chem 281:1840–1852
51. 51. T Sodeman SF Bronk PJ Roberts 2000 Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas Am J Physiol Gastrointest Liver Physiol 278 G992 999 10859230 1:CAS:528:DC%2BD3cXks1Knu70%3D Sodeman T, Bronk SF, Roberts PJ et al (2000) Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. Am J Physiol Gastrointest Liver Physiol 278:G992–999
52. 52. C Voelkel-Johnson 2003 An antibody against DR4 (TRAIL-R1) in combination with doxorubicin selectively kills malignant but not normal prostate cells Cancer Biol Ther 2 283 290 12878867 1:CAS:528:DC%2BD3sXosFCgsbg%3D Voelkel-Johnson C (2003) An antibody against DR4 (TRAIL-R1) in combination with doxorubicin selectively kills malignant but not normal prostate cells. Cancer Biol Ther 2:283–290