Sodium selenite enhances glutathione peroxidase activity and DNA strand breaks in hepatoma induced by N-nitrosodiethylamine and promoted by phenobarbital

Molecular and Cellular Biochemistry

Volumn 310, Issue 1-2, 2008, Pages 129-139

  Thirunavukkarasu, C ^a,b   Premkumar, K ^a   Sheriff, A K ^c   Sakthisekaran, D ^a  

^a UNIVERSITY OF MADRAS   (India)

^b PERIYAR UNIVERSITY   (India)

^c ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Comet assay; DNA damage; Hepatoma; Selenite

Indexed keywords

DIETHYLNITROSAMINE; GLUTATHIONE PEROXIDASE; PHENOBARBITAL; SELENIUM; SODIUM SELENITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PREVENTION; CHEMOPROPHYLAXIS; COMET ASSAY; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVITY; KIDNEY INJURY; LIVER CELL; LIVER CELL CARCINOMA; LIVER NODULE; LUNG INJURY; MALE; NONHUMAN; RAT; SPLEEN INJURY;

ALANINE TRANSAMINASE; ANIMALS; BODY WEIGHT; CARCINOMA, HEPATOCELLULAR; COMET ASSAY; DIETHYLNITROSAMINE; DNA BREAKS, DOUBLE-STRANDED; DRINKING; FEEDING BEHAVIOR; GLUTATHIONE PEROXIDASE; LIVER; LIVER FUNCTION TESTS; LIVER NEOPLASMS; MALE; ORGAN SIZE; PHENOBARBITAL; RATS; RATS, WISTAR; SELENIUM; SERUM ALBUMIN; SODIUM SELENITE;

ANIMALIA; RATTUS;

EID: 39949085237     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9673-5     Document Type: Article

References (73)

1. Chemoprevention Working Group (21 members) (1999) Prevention of cancer in the next millennium: Report of the Chemoprevention Working Group to the American Association for Cancer Research. Cancer Res 59:4743-4758
2. De Flora S, Izzotti A, D'Agostini F, Balansky RM, Noonan D, Albini A (2001) Multiple points of intervention in the prevention of cancer and other mutation related diseases. Mutat Res 480-481:9-22
3. El-Bayoumy K (1991) The role of selenium in cancer prevention. In: DeVita VT, Hellman S, Rosenberg SA (eds) Cancer prevention. J. B. Lippincott, Philadelphia, PA, pp 1-15
4. Thirunavukkarasu C, Jagadeeswaran R, Babu E, Sakthisekaran D (2000) Inhibitory effect of selenium on N-nitrosodiethylamine and Phenobarbital - promoted rat liver carcinogenesis. J Clin Biochem Nutr 28:69-80
5. Yoshizawa K, Willett WC, Morris SJ, Stampfer MJ, Spiegelman D, Rimm EB, Giovannucci E (1998) Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer. J Natl Cancer Inst 90:1219-1224
6. Ghadirian P, Maisonneuve P, Perret C, Kennedy G, Boyle P, Krewski D Lacroix A (2000) A case-control study of toenail selenium and cancer of the breast, colon, and prostate. Cancer Detect Prev 24:305-313
7. Brooks JD, Metter EJ, Chan DW, Sokoll LJ, Landis P, Nelson WG, Muller D, Andres R, Carter HB (2001) Plasma selenium level before diagnosis and the risk of prostate cancer development. J Urol 166:2034-2038
8. Fernandez-Banares F, Cabre E, Esteve M, Mingorance MD, Abad-Lacruz A, Lachica M, Gil A, Gassull MA (2002) Serum selenium and risk of large size colorectal adenomas in a geographical area with a low selenium status. Am J Gastroenterol 97:2103-2108
9. Wang Z, Jiang C, Ganther H, Lu J (2001) Antimitogenic and proapoptotic activities of methylseleninic acid in vascular endothelial cells and associated effects on PI3K-AKT, ERK, JNK, and p38 MAPK Signaling. Cancer Res 61:7171-7178
10. Wang Z, Jiang C, Lu J (2002) Induction of caspase-mediated apoptosis and cell cycle G1 arrest by selenium metabolite methylselenol. Mol Carcinog 34:113-120
11. Gudkov A (2002) Converting p53 from a killer into a healer. Nat Med 8:1196-1198
12. Baines A, Taylor-Parker M, Goulet A, Renaud C, Gerner E, Nelson M (2002) Selenomethionine inhibits growth and suppresses cyclooxygenase-2 (COX-2) protein expression in human colon cancer cell lines. Cancer Biol Ther 4:370-374
13. Ip C, Dong Y (2001) Methylselenocysteine modulates proliferation and apoptosis biomarkers in premalignant lesions of the rat mammary gland. Anticancer Res 21:863-867
14. Lu J, Jiang C, Kaeck M, Ganther H, Vadhanavikit S, Ip C, Thompson H (1995) Dissociation of the genotoxic and growth inhibitory effects of selenium. Biochem. Pharmacol 50:213-221
15. Lipinski B (2005) Rationale for the treatment of cancer with sodium selenite. Med Hypotheses 64:806-810
16. Wycherly BJ, Moak MA, Christensen MJ (2004) High dietary intake of sodium selenite induces oxidative DNA damage in rat liver. Nutr Cancer 48:78-83
17. Al-Taie OH, Seufert J, Karvar S, Adolph C, Mork H, Scheurlen M, Kohrle J, Jakob F (2003) Selenium supplementation enhances low selenium levels and stimulates glutathione peroxidase activity in peripheral blood and distal colon mucosa in past and present carriers of colon adenomas. Nutr Cancer 46:125-130
18. Thirunavukkarasu C, Sakthisekaran D (2001) Effect of selenium on N-nitrosodiethylamine-induced multistage hepatocarcinogenesis with reference to lipid peroxidation and enzymic antioxidants. Cell Biochem Funct 19:27-35
19. Thirunavukkarasu C, Babu E, Ebrahim AS, Chandramohan N, Sakthisekaran D (2004) Antioxidant-associated chemoprevention by sodium selenite in N-nitrosodiethylamine-induced and phenobarbital-promoted hepatocarcinogenesis in rats. Cell Biochem Funct 22:265-271
20. Ip C (1998) Lessons from basic research in selenium and cancer prevention. J Nutr 128:1845-1854
21. Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guigo R, Gladyshev VN (2003) Characterization of mammalian selenoproteomes. Science 300:1439-1443
22. Raich PC, Lu J, Thompson HJ, Combs GF Jr (2001) Selenium in cancer prevention: Clinical issues and implications. Cancer Invest 19:540-553
23. Martinet W, Knaapen MW, De Meyer GR, Herman AG, Kockx MM (2001) Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering. Circ Res 88:733-739
24. Kockx MM, Muhring J, Knaapen MW, de Meyer GR (1998) RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis. Am J Pathol 152:885-888
25. Shen H, Ong C (2000) Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility. Free Radic Biol Med 28:529-536
26. Halliwell B (2000) Why and how should we measure oxidative DNA damage in nutritional studies? How far have we come? Am J Clin Nutr 72:1082-1087
27. Lindahl T, Wood RD (1999) Quality control by DNA repair. Science 286:1897-1905
28. Rehman A, Nourooz-Zadeh J, Moller W, Tritschler H, Pereira P, Halliwell B (1999) Increased oxidative damage to all DNA bases in patients with type II diabetes mellitus. FEBS Lett 448:120-122
29. Collins AR (2002) Comet assay - principles, applications, and limitations. Methods Mol Biol 203:163-177
30. Abt G, Vaghef H, Gebhart E, Dahlgren CV, Hellman B (1997) The role of N-acetylcysteine as a putative radioprotective agent on X-ray-induced DNA damage as evaluated by alkaline single-cell gel electrophoresis. Mutat Res 384:55-64
31. Olive PL, Wlodek D, Banath JP (1991) DNA double-strand breaks measured in individual cells subjected to gel electrophoresis. Cancer Res 51:4671-4676
32. Barbouti A, Doulias PT, Nousis L, Tenopoulou M, Galaris D (2002) DNA damage and apoptosis in hydrogen peroxide-exposed Jurkat cells: Bolus addition versus continuous generation of H(2)O(2). Free Radic Biol Med 33:691-702
33. Godard T, Deslandes E, Lebailly P, Vigreux C, Sichel F, Poul JM, Gauduchon P (1999) Early detection of staurosporine-induced apoptosis by comet and annexin V assays. Histochem Cell Biol 112:155-161
34. Kindzelskii AL, Petty HR (2002) Ultrasensitive detection of DNA damage by the combination of the comet and TUNEL assays. Methods Mol Biol 203:195-201
35. Newberne PM, Bieri JG, Briggs GM, Nesheim MC (1978) Control of diets in laboratory animal experimentation. Inst Lab Anim Resou News 21:A1-A12
36. Dhawan A, Mathur N, Seth PK (2001) The effect of smoking and eating habit on DNA damage in Indian populations as measured in the comet assay. Mutat Res 474:121-128
37. Singh NP, McCoy MT, Tice RR, Schnider EL (1988) A simple technique for the quanitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191
38. Olson OE, Palmer SI, Carey EE (1975) Modification of the official fluorometric method for selenium in plants. J Assoc Off Anal Chem 58:117-121
39. Rotruck JT, Pope AL, Ganther EH, Swanson AB, Hafeman GD, Hoekstra GW (1973) Selenium biochemical role as a component of glutathione peroxidase. Science 179:588-590
40. King J (1965) The dehydrogenases or oxido reductase-lactate dehydrogenase. In: King J (ed) Practical clinical enzymology. D Van Nostrand Company Ltd., London, pp 83-93
41. King J (1965) The transferase-alanine and aspartate transaminase. In: King J (ed) Practical clinical enzymology. D Van Nostrand Company Ltd., London, pp 121-138
42. Massey V, Williams CH (1965) On the reaction mechanism of yeast glutathione reductase. J Biol Chem 240:4470-4480
43. Reinhold JG (1953) Manual determination of serum total protein albumin and globulin fractions by Buiret method. In: Reiner M (ed) Standard methods in clinical chemistry, vol 1. Academic Press, New York, p 88
44. Meuillet E, Stratton S, Cherukuri DP, Goulet AC, Kagey J, Porterfield B, Nelson MA (2004) Chemoprevention of prostate cancer with selenium: An update on current clinical trials and preclinical findings. J Cell Biochem 91:443-458
45. Leist M, Maurer S, Schultz M, Elsner A, Gawlik D, Brigelius-Flohe R (1999) Cytoprotection against lipid hydroperoxides correlates with increased glutathione peroxidase activities, but not selenium uptake from different selenocompounds. Biol Trace Elem Res 68:159-174
46. Thompson HJ, Ip C (1991) Temporal changes in tissue glutathione in response to chemical form, dose, and duration of selenium treatment. Relevance to cancer chemoprevention by selenium. Biol Trace Elem Res 30:163-173
47. Thirunavukkarasu C, Sakthisekaran D (2003) Effect of dietary selenite on N-nitrosodiethylamine-induced and phenobarbital promoted multistage hepatocarcinogenesis in rat: Reflection in some minerals. Biomed Pharmacother 57:416-421
48. Keyer K, Imlay A (1996) Superoxide accelerates DNA damage by elevating free-iron levels. Proc Natl Acad Sci USA 93:13635-13640
49. Zheng QS, Zheng RL (2002) Effects of ascorbic acid and sodium selenite on growth and redifferentiation in human hepatoma cells and its mechanisms. Pharmazie 57:265-269
50. Thirunavukkarasu C, Sakthisekaran D (2003) Stabilization of membrane bound enzyme profiles by sodium selenite in N-nitrosodiethylamine induced and phenobarbital promoted hepatocarcinogenesis in rats. Biomed Pharmacother 57:117-123
51. Halliwell B, Aruoma OI (1991) DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian cells. FEBS Lett 281:9-19
52. Jackson SP (2002) Sensing and repairing DNA double-strand breaks. Carcinogenesis 23:687-696
53. Samarasinghe DA, Tapner M, Farrell GC (2000) Role of oxidative stress in hypoxia-reoxygenation injury to cultured rat hepatic sinusoidal endothelial cells. Hepatology 31:160-165
54. Younes M, Kayser E, Strubelt O (1992) Effect of antioxidants on hypoxia/ reoxygenation-induced injury in isolated perfused rat liver. Pharmacol Toxicol 71:278-283
55. Lipinski B (2005) Rationale for the treatment of cancer with sodium selenite. Med Hypotheses 64:806-810
56. Tarze A, Dauplais M, Grigoras I, Lazard M, Ha-Duong NT, Barbier F, Blanquet S, Plateau P (2007) Extracellular production of hydrogen selenide accounts for thiol-assisted toxicity of selenite against Saccharomyces cerevisiae. J Biol Chem 282:8759-8767
57. Drake EN (2006) Cancer chemoprevention: Selenium as a prooxidant, not an antioxidant. Med Hypotheses 67:318-322
58. Chakrabarti S, Brodeur J (1985) Influence of selenium on the metabolism of bromobenzene and a possible relationship to its hepatotoxicity. Environ Res 37:327-339
59. Yin SA, Sato I, Hosokawa Y, Niizeki S, Tojo H, Yamaguchi K (1991) Effects of dietary zinc and cadmium on tissue selenium concentration and glutathione peroxidase activity in rats fed DL-selenomethionine or sodium selenite. J Nutr Sci Vitaminol 37:29-37
60. Bell RR, Nonavinakere VK, Soliman MR, Early JL (1991) Effect of in vitro treatment of rat hepatocytes with selenium, and/or cadmium on cell viability, glucose output, and cellular glutathione. Toxicology 69:111-119
61. Chung AS, Maines MD, Reynolds WA (1982) Inhibition of the enzymes of glutathione metabolism by mercuric chloride in the rat kidney: Reversal by selenium. Biochem Pharmacol 31:3093-3100
62. Anundi I, Hogberg J, Stahl A (1982) Involvement of glutathione reductase in selenite metabolism and toxicity, studied in isolated rat hepatocytes. Arch Toxicol 50:113-123
63. Rayman MP (2000) The importance of selenium to human health. Lancet 356:233-241
64. Hatfield DL, Gladyshev VN (2002) How selenium has altered our understanding of the genetic code. Mol Cell Biol 22:3565-3576
65. Tapiero H, Townsend DM, Tew KD (2003) The antioxidant role of selenium and seleno-compounds. Biomed Pharmacother 57:134-144
66. Ip C, Thompson HJ, Zhu Z, Ganther HE (2000) In vitro and in vivo studies of methylseleninic acid: Evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention. Cancer Res 60:2882-2886
67. Menter DG, Sabichi AL, Lippman SM (2000) Selenium effects on prostate cell growth. Cancer Epidemiol Biomarkers Prev 9:1171-1182
68. Zhong W, Oberley TD (2001) Redox-mediated effects of selenium on apoptosis and cell cycle in the LNCaP human prostate cancer cell line. Cancer Res 61:7071-7078
69. Jiang C, Wang Z, Ganther H, Lu J (2001) Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells. Cancer Res 61:3062-3070
70. Venkateswaran V, Klotz LH, Fleshner NE (2002) Selenium modulation of cell proliferation and cell cycle biomarkers in human prostate carcinoma cell lines. Cancer Res 62:2540-2545
71. Dong Y, Lee SO, Zhang H, Marshall J, Gao AC, Ip C (2004) Prostate specific antigen expression is down-regulated by selenium through disruption of androgen receptor signaling. Cancer Res 64:19-22
72. Gallegos A, Berggren M, Gasdaska JR, Powis G (1997) Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium. Cancer Res 57:4965-4970
73. Anestal K, Arner ES (2003) Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocytsteine. J Biol Chem 278:15966-15972