Anticancer activity of botanical alkyl hydroquinones attributed to topoisomerase II poisoning

Toxicology and Applied Pharmacology

Volumn 227, Issue 3, 2008, Pages 331-338

  Huang, Cheng Po ^a   Fang, Woei Horng ^a,b   Lin, Liang In ^a,b   Chiou, Robin Y ^c   Kan, Lou Sing ^d   Chi, Nai Hui ^a   Chen, Yun Ru ^a   Lin, Tin Yu ^a   Lin, Shwu Bin ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^d INSTITUTE OF CHEMISTRY   (Taiwan)

Author keywords

Alkyl hydroquinone; Anticancer drug; Topoisomerase II poison

Indexed keywords

ACETYLCYSTEINE; BOTANICAL HYDROQUINONE; DNA TOPOISOMERASE (ATP HYDROLYSING); HERBACEOUS AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CHROMOSOME BREAKAGE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA SYNTHESIS; DRUG STRUCTURE; DRUG TARGETING; LEUKEMIA; MALE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; RAT;

ANACARDIACEAE; RATTUS; TOXICODENDRON SUCCEDANEUM;

EID: 39849096557     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.11.014     Document Type: Article

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