Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: A potential mechanism underlying the genotoxic and carcinogenic effects of benzene

Chemico-Biological Interactions

Volumn 153-154, Issue , 2005, Pages 207-216

  Eastmond, David A ^a   Mondrala, Scott T ^a   Hasegawa, Leslie ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Benzene; Genotoxicity; Hydroquinone; Leukemia; Myeloperoxidase; Topoisomerase II

Indexed keywords

DITHIOTHREITOL; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; HYDROGEN PEROXIDE; HYDROQUINONE; MYELOPEROXIDASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CARCINOGENICITY; DNA PURIFICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME ISOLATION; GENOTOXICITY; LEUKEMIA; MOLECULAR MECHANICS;

BENZENE; BENZOQUINONES; CARCINOGENS; DITHIOTHREITOL; DNA TOPOISOMERASES, TYPE II; DNA, KINETOPLAST; HL-60 CELLS; HUMANS; HYDROGEN PEROXIDE; HYDROQUINONES; LEUKEMIA; PEROXIDASE;

ANIMALIA;

EID: 20444414463     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2005.03.024     Document Type: Article

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