Mutation variants generated from nonvirulent coxsackievirus B3 acquire virulence phenotypes by active virus replication

Intervirology

Volumn 50, Issue 6, 2008, Pages 447-453

  Seo, Ilseon ^a   Jee, Youngmee ^b   Ahn, Jeonghyun ^a   Jun, Eun Jung ^a   Kim, Donghou ^a   Joo, Chul Hyun ^a   Kim, Yoo Kyum ^a   Lee, Heuiran ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Korea Centers for Disease Control and Prevention   (South Korea)

Author keywords

Coxsackievirus B3; Genotype analysis; Mutagenesis; Virus replication

Indexed keywords

NUCLEOTIDE;

5' UNTRANSLATED REGION; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS B3; DISEASE SEVERITY; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HISTOPATHOLOGY; IN VIVO STUDY; MORTALITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS VIRULENCE;

5' UNTRANSLATED REGIONS; ANIMALS; COXSACKIEVIRUS INFECTIONS; DNA, VIRAL; ENTEROVIRUS B, HUMAN; GENOME, VIRAL; HELA CELLS; HUMANS; MICE; PHENOTYPE; VIRULENCE; VIRUS REPLICATION;

COXSACKIEVIRUS;

EID: 39749196721     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000115950     Document Type: Article

References (40)

1. Rotbart HA: Meningitis and encephalitis; in Rotbart HA (ed): Human Enterovirus Infections. Washington, American Society for Microbiology, 1995, pp 271-289.
2. Ramsingh AI: Coxsackieviruses and pancreatitis. Front Biosci 1997;2:e53-e62.
3. Bowles NE, Richardson PJ, Olsen EG, Archard LC: Detection of coxsackie-B-virus-specific RNA sequences in myocardial biopsy samples from patients with myocarditis and dilated cardiomyopathy. Lancet 1986;1:1120-1123.
4. Baboonian C, Davies MJ, Booth JC, McKenna WJ: Coxsackie B viruses and human heart disease. Curr Top Microbiol Immunol 1997;223:31-52.
5. Modlin JF, Rotbart HA: Group B coxsackie disease in children. Curr Top Microbiol Immunol 1997;223:53-80.
6. Racaniello VR: Picornaviridae: the viruses and their replication; in Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (eds): Fields Virology, ed 4. Philadelphia, Lippincott Williams & Wilkins, 2001, pp 685-722.
7. Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krithivas A, Hong JS, Horwitz MS, Crowell RL, Finberg RW: Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5. Science 1997;275:1320-1323.
8. Bergelson JM, Mohanty JG, Crowell RL, St John NF, Lublin DM, Finberg RW: Coxsackievirus B3 adapted to growth in RD cells binds to decay-accelerating factor (CD55). J Virol 1995;69:1903-1906.
9. Coyne CB, Bergelson JM: Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions. Cell 2006;124:119-131.
10. Ahn J, Joo CH, Seo I, Kim D, Hong HN, Kim YK, Lee H: Characteristics of apoptotic cell death induced by coxsackievirus B in permissive Vero cells. Intervirology 2003;46:245-251.
11. Ahn J, Choi J, Joo CH, Seo I, Kim D, Yoon SY, Kim YK, Lee H: Susceptibility of mouse primary cortical neuronal cells to coxsackievirus B. J Gen Virol 2004;85(Pt 6):1555-1564.
12. Ahn J, Joo CH, Seo I, Kim D, Kim YK, Lee H: All CVB serotypes and clinical isolates induce irreversible cytopathic effects in primary cardiomyocytes. J Med Virol 2005;75:290-294.
13. Gauntt C, Huber S: Coxsackievirus experimental heart diseases. Front Biosci 2003;8:e23-e35.
14. Klingel K, Selinka HC, Huber M, Sauter M, Leube M, Kandolf R: Molecular pathology and structural features of enteroviral replication. Toward understanding the pathogenesis of viral heart disease. Herz 2000;25:216-220.
15. Lee C, Maull E, Chapman N, Tracy S, Wood J, Gauntt C: Generation of an infectious cDNA of a highly cardiovirulent coxsackievirus B3(CVB3m) and comparison to other infectious CVB3 cDNAs. Virus Res 1997;50:225-235.
16. Tracy S, Chapman N, Tu Z: Coxsackievirus B3 from an infectious cDNA copy of the genome is cardiovirulent in mice. Arch Virol 1992;122:399-409.
17. Chapman N, Tu Z, Tracy S, Gauntt C: An infectious cDNA copy of the genome of a non-cardiovirulent coxsackievirus B3 strain: its complete sequence analysis and comparison to the genomes of cardiovirulent coxsackieviruses. Arch Virol 1994;135:115-130.
18. Joo CH, Hong HN, Kim EO, Im JO, Yoon SY, Ye JS, Moon MS, Kim D, Lee H, Kim YK: Coxsackievirus B3 induces apoptosis in the early phase of murine myocarditis: a comparative analysis of cardiovirulent and non-cardiovirulent strains. Intervirology 2003;46:135-140.
19. Tu Z, Chapman N, Hufnagel G, Tracy S, Romero JR, Barry WH, Zhao L, Currey K, Shapiro B: The cardiovirulent phenotype of coxsackievirus B3 is determined at a single site in the genomic 5′ nontranslated region. J Virol 1995;69:4607-4618.
20. Harvala H, Kalimo H, Dahllund L, Santti J, Hughes P, Hyypiä T, Stanway G: Mapping of tissue tropism determinants in coxsackievirus genomes. J Gen Virol 2002;83(Pt 7):1697-1706.
21. Dan M, Chantler JK: A genetically engineered attenuated coxsackievirus B3 strain protects mice against lethal infection. J Virol 2005;79:9285-9295.
22. Halim S, Ramsingh AI: A point mutation in VP1 of coxsackievirus B4 alters antigenicity. Virology 2000;269:86-94.
23. Mena I, Fischer C, Gebhard JR, Perry CM, Harkins S, Whitton JL: Coxsackievirus infection of the pancreas: evaluation of receptor expression, pathogenesis, and immunopathology. Virology 2000;271:276-288.
24. Anderson DR, Wilson JE, Carthy CM, Yang D, Kandolf R, McManus BM: Direct interactions of coxsackievirus B3 with immune cells in the splenic compartment of mice susceptible or resistant to myocarditis. J Virol 1996;70:4632-4645.
25. Moon MS, Joo CH, Hwang IS, Ye JS, Jun EJ, Lee HS, Kim D, Lee MJ, Lee H, Kim YK: Distribution of viral RNA in mouse tissues during acute phase of coxsackievirus B5 infection. Intervirology 2005;48:153-160.
26. Chow LH, Beisel KW, McManus BM: Enteroviral infection of mice with severe combined immunodeficiency. Evidence for direct viral pathogenesis of myocardial injury. Lab Invest 1992;66:24-31.
27. Klingel K, Rieger P, Mall G, Selinka HC, Huber M, Kandolf R: Visualization of enteroviral replication in myocardial tissue by ultrastructural in situ hybridization: identification of target cells and cytopathic effects. Lab Invest 1998;78:1227-1237.
28. Leipner C, Grün K, Borchers M, Stelzner A: The outcome of coxsackievirus B3-(CVB3-) induced myocarditis is influenced by the cellular immune status. Herz 2000;25:245-248.
29. Henke A, Huber S, Stelzner A, Whitton JL: The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis. J Virol 1995;69:6720-6728.
30. van Ooij MJ, Vogt DA, Paul A, Castro C, Kuijpers J, van Kuppeveld FJ, Cameron CE, Wimmer E, Andino R, Melchers WJ: Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis. J Gen Virol 2006;87(Pt 1):103-113.
31. Lee C, Maull E, Chapman N, Tracy S, Gauntt C: Genomic regions of coxsackievirus B3 associated with cardiovirulence. J Med Virol 1997;52:341-347.
32. Dunn JJ, Bradrick SS, Chapman NM, Tracy SM, Romero JR: The stem loop II within the 5′ nontranslated region of clinical coxsackievirus B3 genomes determines cardiovirulence phenotype in a murine model. J Infect Dis 2003;187:1552-1561.
33. Suhy DA, Giddings TH Jr, Kirkegaard K: Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. J Virol 2000;74:8953-8965.
34. Banerjee R, Echeverri A, Dasgupta A: Poliovirus-encoded 2C polypeptide specifically binds to the 3′-terminal sequences of viral negative-strand RNA. J Virol 1997;71:9570-9578.
35. Wessels E, Duijsings D, Notebaart RA, Melchers WJ, van Kuppeveld FJ: A proline-rich region in the coxsackievirus 3A protein is required for the protein to inhibit endoplasmic reticulum-to-Golgi transport. J Virol 2005;79:5163-5173.
36. Doedens JR, Giddings TH Jr, Kirkegaard K: Inhibition of endoplasmic reticulum-to-Golgi traffic by poliovirus protein 3A: genetic and ultrastructural analysis. J Virol 1997;71:9054-9064.
37. Teterina NL, Rinaudo MS, Ehrenfeld E: Strand-specific RNA synthesis defects in a poliovirus with a mutation in protein 3A. J Virol 2003;77:12679-12691.
38. Yang Y, Liang Y, Qu L, Chen Z, Yi M, Li K, Lemon SM: Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor. Proc Natl Acad Sci USA 2007;104:7253-7258.
39. Pasch A, Küpper JH, Wolde A, Kandolf R, Selinka HC: Comparative analysis of virus-host cell interactions of haemagglutinating and non-haemagglutinating strains of coxsackievirus B3. J Gen Virol 1999;80(Pt 12):3153-3158.
40. Selinka HC, Wolde A, Pasch A, Klingel K, Schnorr JJ, Küpper JH, Lindberg AM, Kandolf R: Comparative analysis of two coxsackievirus B3 strains: putative influence of virus-receptor interactions on pathogenesis. J Med Virol 2002;67:224-233.