메뉴 건너뛰기




Volumn 140, Issue 6, 2008, Pages 665-672

Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: Frequent late relapses but good overall survival

(16)  Forestier, Erik a   Heyman, Mats b   Andersen, Mette K c   Autio, Kirsi d   Blennow, Elisabeth e   Borgström, Georg d   Golovleva, Irina a   Heim, Sverre f,g   Heinonen, Kristina h   Hovland, Randi i   Johannsson, Johann H j   Kerndrup, Gitte k   Nordgren, Ann e   Rosenquist, Richard l   Swolin, Birgitta m   Johansson, Bertil n  


Author keywords

Acute lymphoblastic leukaemia; Childhood; ETV6 RUNX1; Prognosis; Relapse; t(12; 21)(p13; q22)

Indexed keywords

TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR RUNX1;

EID: 39749177335     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2008.06980.x     Document Type: Article
Times cited : (77)

References (53)
  • 2
    • 33947709535 scopus 로고    scopus 로고
    • Characteristics of patients with TEL-AML1-positive acute lymphoblastic leukemia with single or multiple fusions
    • Al-Sweedan, S.A., Neglia, J.P., Steiner, M.E., Bostrom, B.C., Casey, T. Hirsch, B.A. (2007) Characteristics of patients with TEL-AML1-positive acute lymphoblastic leukemia with single or multiple fusions. Pediatric Blood & Cancer, 48, 510 514.
    • (2007) Pediatric Blood & Cancer , vol.48 , pp. 510-514
    • Al-Sweedan, S.A.1    Neglia, J.P.2    Steiner, M.E.3    Bostrom, B.C.4    Casey, T.5    Hirsch, B.A.6
  • 4
    • 6344289461 scopus 로고    scopus 로고
    • Incidence and relevance of secondary chromosome abnormalities in childhood TEL/AML1 + acute lymphoblastic leukemia: An interphase FISH analysis
    • Attarbaschi, A., Mann, G., König, M., Dworzak, M.N., Trebo, M.M., Mühlegger, N., Gadner, H. Haas, O.A. (2004) Incidence and relevance of secondary chromosome abnormalities in childhood TEL/AML1 + acute lymphoblastic leukemia: an interphase FISH analysis. Leukemia, 18, 1611 1616.
    • (2004) Leukemia , vol.18 , pp. 1611-1616
    • Attarbaschi, A.1    Mann, G.2    König, M.3    Dworzak, M.N.4    Trebo, M.M.5    Mühlegger, N.6    Gadner, H.7    Haas, O.A.8
  • 8
    • 0031752848 scopus 로고    scopus 로고
    • Surface antigen phenotype can predict TEL-AML1 rearrangement in childhood B-precursor ALL: A Pediatric Oncology Group study
    • Borowitz, M.J., Rubnitz, J., Nash, M., Pullen, D.J. Camitta, B. (1998) Surface antigen phenotype can predict TEL-AML1 rearrangement in childhood B-precursor ALL: a Pediatric Oncology Group study. Leukemia, 12, 1764 1770.
    • (1998) Leukemia , vol.12 , pp. 1764-1770
    • Borowitz, M.J.1    Rubnitz, J.2    Nash, M.3    Pullen, D.J.4    Camitta, B.5
  • 10
    • 12944277156 scopus 로고    scopus 로고
    • Quantitative multiparametric immunophenotyping in acute lymphoblastic leukemia: Correlation with specific genotype. I. ETV6/AML1 ALLs identification
    • De Zen, L., Orfao, A., Cazzaniga, G., Masiero, L., Cocito, M.G., Spinelli, M., Rivolta, A., Biondi, A., Zanesco, L. Basso, G. (2000) Quantitative multiparametric immunophenotyping in acute lymphoblastic leukemia: correlation with specific genotype. I. ETV6/AML1 ALLs identification. Leukemia, 14, 1225 1231.
    • (2000) Leukemia , vol.14 , pp. 1225-1231
    • De Zen, L.1    Orfao, A.2    Cazzaniga, G.3    Masiero, L.4    Cocito, M.G.5    Spinelli, M.6    Rivolta, A.7    Biondi, A.8    Zanesco, L.9    Basso, G.10
  • 11
    • 0043165062 scopus 로고    scopus 로고
    • Persistence of TEL-AML1 transcript in acute lymphoblastic leukemia in long-term remission
    • Endo, C., Oda, M., Nishiuchi, R. Seino, Y. (2003) Persistence of TEL-AML1 transcript in acute lymphoblastic leukemia in long-term remission. Pediatrics International, 45, 275 280.
    • (2003) Pediatrics International , vol.45 , pp. 275-280
    • Endo, C.1    Oda, M.2    Nishiuchi, R.3    Seino, Y.4
  • 12
    • 0035437159 scopus 로고    scopus 로고
    • Origins of "late" relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes
    • Ford, A.M., Fasching, K., Panzer-Grümayer, E.R., Koenig, M., Haas, O.A. Greaves, M.F. (2001) Origins of "late" relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes. Blood, 98, 558 564.
    • (2001) Blood , vol.98 , pp. 558-564
    • Ford, A.M.1    Fasching, K.2    Panzer-Grümayer, E.R.3    Koenig, M.4    Haas, O.A.5    Greaves, M.F.6
  • 13
    • 33747468624 scopus 로고    scopus 로고
    • The incidence peaks of the childhood acute leukemias reflect specific cytogenetic aberrations
    • Forestier, E. Schmiegelow, K. (2006) The incidence peaks of the childhood acute leukemias reflect specific cytogenetic aberrations. Journal of Pediatric Hematology/Oncology, 28, 486 495.
    • (2006) Journal of Pediatric Hematology/Oncology , vol.28 , pp. 486-495
    • Forestier, E.1    Schmiegelow, K.2
  • 19
    • 0035021732 scopus 로고    scopus 로고
    • Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: Results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol
    • Hann, I., Vora, A., Harrison, G., Harrison, C., Eden, O., Hill, F., Gibson, B. Richards, S. (2001) Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol. British Journal of Haematology, 113, 103 114.
    • (2001) British Journal of Haematology , vol.113 , pp. 103-114
    • Hann, I.1    Vora, A.2    Harrison, G.3    Harrison, C.4    Eden, O.5    Hill, F.6    Gibson, B.7    Richards, S.8
  • 20
    • 0031440492 scopus 로고    scopus 로고
    • Incidence of TEL/AML1 fusion gene analyzed consecutively in children with acute lymphoblastic leukemia in relapse
    • Harbott, J., Viehmann, S., Borkhardt, A., Henze, G. Lampert, F. (1997) Incidence of TEL/AML1 fusion gene analyzed consecutively in children with acute lymphoblastic leukemia in relapse. Blood, 90, 4933 4937.
    • (1997) Blood , vol.90 , pp. 4933-4937
    • Harbott, J.1    Viehmann, S.2    Borkhardt, A.3    Henze, G.4    Lampert, F.5
  • 22
    • 0034667267 scopus 로고    scopus 로고
    • TEL/AML-1 fusion gene: Its frequency and prognostic significance in childhood acute lymphoblastic leukemia
    • Jamil, A., Theil, K.S., Kahwash, S., Ruymann, F.B. Klopfenstein, K.J. (2000) TEL/AML-1 fusion gene: its frequency and prognostic significance in childhood acute lymphoblastic leukemia. Cancer Genetics and Cytogenetics, 122, 73 78.
    • (2000) Cancer Genetics and Cytogenetics , vol.122 , pp. 73-78
    • Jamil, A.1    Theil, K.S.2    Kahwash, S.3    Ruymann, F.B.4    Klopfenstein, K.J.5
  • 23
    • 33749252172 scopus 로고    scopus 로고
    • High incidence of the ETV6/RUNX1 fusion gene in paediatric precursor B-cell acute lymphoblastic leukaemias with trisomy 21 as the sole cytogenetic change: A Nordic series of cases diagnosed 1989-2005
    • Karrman, K., Forestier, E., Andersen, M.K., Autio, K., Borgström, G., Heim, S., Heinonen, K., Hovland, R., Kerndrup, G. Johansson, B. (2006) High incidence of the ETV6/RUNX1 fusion gene in paediatric precursor B-cell acute lymphoblastic leukaemias with trisomy 21 as the sole cytogenetic change: a Nordic series of cases diagnosed 1989-2005. British Journal of Haematology, 135, 352 354.
    • (2006) British Journal of Haematology , vol.135 , pp. 352-354
    • Karrman, K.1    Forestier, E.2    Andersen, M.K.3    Autio, K.4    Borgström, G.5    Heim, S.6    Heinonen, K.7    Hovland, R.8    Kerndrup, G.9    Johansson, B.10
  • 24
    • 0033000862 scopus 로고    scopus 로고
    • An investigation of the t(12;21) rearrangement in children with B-precursor acute lymphoblastic leukaemia using cytogenetic and molecular methods
    • Kempski, H., Chalker, J., Chessells, J., Sturt, N., Brickell, P., Webb, J., MacDonald Clink, J. Reeves, B. (1999) An investigation of the t(12;21) rearrangement in children with B-precursor acute lymphoblastic leukaemia using cytogenetic and molecular methods. British Journal of Haematology, 105, 684 689.
    • (1999) British Journal of Haematology , vol.105 , pp. 684-689
    • Kempski, H.1    Chalker, J.2    Chessells, J.3    Sturt, N.4    Brickell, P.5    Webb, J.6    MacDonald Clink, J.7    Reeves, B.8
  • 25
    • 0037866469 scopus 로고    scopus 로고
    • Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: Evidence for the persistence of a preleukemic clone
    • Konrad, M., Metzler, M., Panzer, S., Östreicher, I., Peham, M., Repp, R., Haas, O.A., Gadner, H. Panzer-Grümayer, E.R. (2003) Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: evidence for the persistence of a preleukemic clone. Blood, 101, 3635 3640.
    • (2003) Blood , vol.101 , pp. 3635-3640
    • Konrad, M.1    Metzler, M.2    Panzer, S.3    Östreicher, I.4    Peham, M.5    Repp, R.6    Haas, O.A.7    Gadner, H.8    Panzer-Grümayer, E.R.9
  • 29
    • 0034854751 scopus 로고    scopus 로고
    • Characterization of additional genetic events in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion: A molecular cytogenetics study
    • Ma, S.K., Wan, T.S.K., Cheuk, A.T.C., Fung, L.F., Chan, G.C.F., Chan, S.Y., Ha, S.Y. Chan, L.C. (2001) Characterization of additional genetic events in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion: a molecular cytogenetics study. Leukemia, 15, 1442 1447.
    • (2001) Leukemia , vol.15 , pp. 1442-1447
    • Ma, S.K.1    Wan, T.S.K.2    Cheuk, A.T.C.3    Fung, L.F.4    Chan, G.C.F.5    Chan, S.Y.6    Ha, S.Y.7    Chan, L.C.8
  • 30
    • 0032718818 scopus 로고    scopus 로고
    • TEL-AML1 fusion identifies a subset of children with standard risk acute lymphoblastic leukemia who have an excellent prognosis when treated with therapy that includes a single delayed intensification
    • Maloney, K.W., McGavran, L., Murphy, J.R., Odom, L.F., Stork, L., Wei, Q. Hunger, S.P. (1999) TEL-AML1 fusion identifies a subset of children with standard risk acute lymphoblastic leukemia who have an excellent prognosis when treated with therapy that includes a single delayed intensification. Leukemia, 13, 1708 1712.
    • (1999) Leukemia , vol.13 , pp. 1708-1712
    • Maloney, K.W.1    McGavran, L.2    Murphy, J.R.3    Odom, L.F.4    Stork, L.5    Wei, Q.6    Hunger, S.P.7
  • 34
    • 0034798902 scopus 로고    scopus 로고
    • Characteristics of TEL/AML-1 positive acute lymphoblastic leukemia in Hungarian children
    • Pajor, L., Lacza, Á., Jáksó, P. Kajtár, B. (2001) Characteristics of TEL/AML-1 positive acute lymphoblastic leukemia in Hungarian children. Medical and Pediatric Oncology, 37, 409 411.
    • (2001) Medical and Pediatric Oncology , vol.37 , pp. 409-411
    • Pajor, L.1    Lacza, Á.2    Jáksó, P.3    Kajtár, B.4
  • 35
    • 0347357869 scopus 로고    scopus 로고
    • Clonal variation of the immunogenotype in relapsed ETV6/RUNX1-positive acute lymphoblastic leukemia indicates subclone formation during early stages of leukemia development
    • Peham, M., Konrad, M., Harbott, J., König, M., Haas, O.A. Panzer-Grümayer, E.R. (2004) Clonal variation of the immunogenotype in relapsed ETV6/RUNX1-positive acute lymphoblastic leukemia indicates subclone formation during early stages of leukemia development. Genes, Chromosomes and Cancer, 39, 156 160.
    • (2004) Genes, Chromosomes and Cancer , vol.39 , pp. 156-160
    • Peham, M.1    Konrad, M.2    Harbott, J.3    König, M.4    Haas, O.A.5    Panzer-Grümayer, E.R.6
  • 36
    • 0033659492 scopus 로고    scopus 로고
    • ETV6/CBFA2 fusions in childhood B-cell precursor acute lymphoblastic leukemia with myeloid markers
    • Rafi, S.K., El Gebaly, H. Qumsiyeh, M.B. (2000) ETV6/CBFA2 fusions in childhood B-cell precursor acute lymphoblastic leukemia with myeloid markers. Diagnostic Molecular Pathology, 9, 184 189.
    • (2000) Diagnostic Molecular Pathology , vol.9 , pp. 184-189
    • Rafi, S.K.1    El Gebaly, H.2    Qumsiyeh, M.B.3
  • 38
    • 0032841521 scopus 로고    scopus 로고
    • Cytogenetic abnormalities associated with the t(12;21): A collaborative study of 169 children with t(12;21)-positive acute lymphoblastic leukemia
    • Raynaud, S.D., Dastugue, N., Zoccola, D., Shurtleff, S.A., Mathew, S. Raimondi, S.C. (1999) Cytogenetic abnormalities associated with the t(12;21): a collaborative study of 169 children with t(12;21)-positive acute lymphoblastic leukemia. Leukemia, 13, 1325 1330.
    • (1999) Leukemia , vol.13 , pp. 1325-1330
    • Raynaud, S.D.1    Dastugue, N.2    Zoccola, D.3    Shurtleff, S.A.4    Mathew, S.5    Raimondi, S.C.6
  • 39
    • 0028330771 scopus 로고
    • T(12;21): A new recurrent translocation in acute lymphoblastic leukemia
    • Romana, S.P., Le Coniat, M. Berger, R. (1994) t(12;21): a new recurrent translocation in acute lymphoblastic leukemia. Genes, Chromosomes and Cancer, 9, 186 191.
    • (1994) Genes, Chromosomes and Cancer , vol.9 , pp. 186-191
    • Romana, S.P.1    Le Coniat, M.2    Berger, R.3
  • 42
    • 0031055374 scopus 로고    scopus 로고
    • Case-control study suggests a favorable impact of TEL rearrangement in patients with B-lineage acute lymphoblastic leukemia treated with antimetabolite-based therapy: A Pediatric Oncology Group study
    • Rubnitz, J.E., Shuster, J.J., Land, V.J., Link, M.P., Pullen, D.J., Camitta, B.M., Pui, C.-H., Downing, J.R. Behm, F.G. (1997) Case-control study suggests a favorable impact of TEL rearrangement in patients with B-lineage acute lymphoblastic leukemia treated with antimetabolite-based therapy: a Pediatric Oncology Group study. Blood, 89, 1143 1146.
    • (1997) Blood , vol.89 , pp. 1143-1146
    • Rubnitz, J.E.1    Shuster, J.J.2    Land, V.J.3    Link, M.P.4    Pullen, D.J.5    Camitta, B.M.6    Pui, C.-H.7    Downing, J.R.8    Behm, F.G.9
  • 47
    • 0035866767 scopus 로고    scopus 로고
    • Molecular quantification of response to therapy and remission status in TEL-AML1-positive childhood ALL by real-time reverse transcription polymerase chain reaction
    • Seeger, K., Kreuzer, K.-A., Lass, U., Taube, T., Buchwald, D., Eckert, C., Körner, G., Schmidt, C.-A. Henze, G. (2001) Molecular quantification of response to therapy and remission status in TEL-AML1-positive childhood ALL by real-time reverse transcription polymerase chain reaction. Cancer Research, 61, 2517 2522.
    • (2001) Cancer Research , vol.61 , pp. 2517-2522
    • Seeger, K.1    Kreuzer, K.-A.2    Lass, U.3    Taube, T.4    Buchwald, D.5    Eckert, C.6    Körner, G.7    Schmidt, C.-A.8    Henze, G.9
  • 48
    • 13344282725 scopus 로고
    • TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis
    • Shurtleff, S.A., Buijs, A., Behm, F.G., Rubnitz, J.E., Raimondi, S.C., Hancock, M.L., Chan, G.C.-F., Pui, C.-H., Grosveld, G. Downing, J.R. (1995) TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. Leukemia, 9, 1985 1989.
    • (1995) Leukemia , vol.9 , pp. 1985-1989
    • Shurtleff, S.A.1    Buijs, A.2    Behm, F.G.3    Rubnitz, J.E.4    Raimondi, S.C.5    Hancock, M.L.6    Chan, G.C.-F.7    Pui, C.-H.8    Grosveld, G.9    Downing, J.R.10
  • 51


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.