Enhancement of star vector-based gene delivery to endothelial cells by addition of RGD-peptide

Bioconjugate Chemistry

Volumn 19, Issue 2, 2008, Pages 558-561

  Ishikawa, Ayaka ^a   Zhou, Yue Min ^a   Kambe, Nobuaki ^b   Nakayama, Yasuhide ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ENDOTHELIAL CELLS; GENE ENCODING; GENE EXPRESSION; MOLECULAR BIOLOGY; PARTICLE SIZE; PEPTIDES; VECTORS;

CATIONICS; DNA COMPLEX; ENDOTHELIAL-CELLS; GENE CARRIER; GENE DELIVERY; GENES EXPRESSION; NONVIRAL; POLYPLEXES; RGD PEPTIDE; STAR VECTOR;

GENE TRANSFER;

ACRYLAMIDE DERIVATIVE; ARGINYLGLYCYLASPARTIC ACID; INTEGRIN; LUCIFERASE; PLASMID DNA; POLY(N,N DIMETHYLAMINOPROPYLACRYLAMIDE); POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; FEASIBILITY STUDY; GENE EXPRESSION; GENE TARGETING; GENE VECTOR; GENETIC CODE; GENETIC TRANSFECTION; HETEROZYGOTE; IN VITRO STUDY; NONHUMAN; PARTICLE SIZE; PROTEIN FOLDING; PROTEIN INTERACTION;

EID: 39749122615     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc700385r     Document Type: Article

References (26)

1. Boussif, O., Lezouclc'h, F., Zanta, M., Mergny, M. D., Scherman, D., Demeneix, B., and Behr, J. P. (1995) A versatile vector for gene and oligonucleotide transfer into cells in culuture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. U.S.A. 92, 7297-7301.
2. Godbey, W. T., Wu, K. K., and Mikos, A. G. (1999) Poly(ethyleneimine) and its role in gene delivery. J. Controlled Release 60, 149-160.
3. Kichler, A. (2004) Gene transfer with modied polyethyleneimine. J. Gene Med. 6 Suppl. 1 S3-S10.
4. Demeneix, B., Hassani, Z., and Behr, J. P. (2004) Towards multifunctional synthetic vectors. Curr. Gene Ther. 4, 445-455.
5. Nakayama, Y., Masuda, T., Nagaishi, M., Hayashi, M., Ohira, M., and Harada-Shiba, M. (2005) High performance gene delivery polymeric vector: nano-structured cationic star polymers (star vector). Curr. Drug Delivery 2, 53-57.
6. Mizuguchi, F., Ooe, Y., Hoshino, S., Shimura, M., Kasahara, T., Kano, S., Ohta, T., Takaku, F., Nakayama, Y., and Ishizaka, Y. (2005) Improved gene expression in resting macrophages using an oligopeptide derived from Vpr of human immunodeficiency virus type-1. Biochem. Biophys. Res. Commun. 338, 1499-1506.
7. Nakayama, Y., Kakei, C., Ishikawa, A., Zhou, Y. M., Nemoto, Y., Uchida, K. (2007) Synthesis and in vitro eveluation of novel star-shaped block copolymers (blocked star vectors) for efficient gene delivery. Bioconjugate Chem. [Epub shead of print].
8. Zhou, Y. M., Ishikawa, A., Okahashi, R., Uchida, K., Nemoto, Y., Nakayama, M., and Nakayama, Y. (2007) Deposition transfection technology using a DNA complex with a thermoresponsive cationic star polymer. J. Controlled Release 123, 239-246.
9. Li, S., and Huang, L. (2000) Gene therapy progress and prospects: non-viral gene therapy by systemic delivery. Gene Ther. 7, 1-34.
10. Luo, D., and Saltzman, W. M. (2000) Enhancement of transfection by physical concentration of DNA at the cell surface. Nat. Biotechnol. 18, 33-37.
11. Gebhart, C. L., and Kabanov, A. K. (2001) Evaluation of polyplexes as gene transfer agents. J. Controlled Release 73, 401-416.
12. Thomas, M., and Klibanov, A. M. (2003) Non-viral gene therapy: polycation-mediated DNA delivery. Appl. Microbiol. Biotechnol. 62, 27-34.
13. Dubruel, P., and Schacht, E. (2006) Vinyl polymers as non-viral gene delivery earners: cunent status and prospects. Macromol. Biosci. 6, 789-810.
14. Otsu, T., Yoshida, M., and Tazaki, T. (1982) A model for living radical polymerization. Makromol. Chem. Rapid Commun. 3, 133-140.
15. Otsu, T., Matsunaga, T., Doi, T., and Matsumoto, A. (1995) Features of living radical polymerization of vinyl monomers in homogeneous system using N,N-diethyldithiocarbamate derivatives as photoiniferters. Eur. Polym. J. 31, 67-78.
16. Varner, J. A., and Cheresh, D. A. (1996) Integrins and cancer. Curr. Opin. Cell Biol. 8, 724-730.
17. Rouslahti, E. (1996) RGD and other recognition sequences for integrins. Annu. Rev. Cell Dev. Biol. 12, 697-715.
18. Logan, D., Abu-Ghazaleh, R., and Blakemore, W., et al. (1993) Structure of a major immunogenic site on foot-and mouth disease virus. Nature 362, 566-568.
19. Isberg, R. R. (1991) Discrimination between interacellular uptake and surface adhesion of bacterial pathogens. Science 252, 934-938.
20. Hart, S. L., Harbottle, R. P., and Cooper, R., et al. (1995) Gene delivery and expression mediated by an intergrin-binding peptide. Gene Ther. 2, 552-554.
21. Erbacher, P., Remy, J.S., and Behr, J. P. (1999) Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway. Gene Ther. 6, 138-145.
22. Kim, W. J., Yockman, J. W., Lee, M., Jeong, J. H., Kim, Y. H., and Kim, S. W. (2005) Soluble Flt-1 gene delivery using PEI-g-PEG-RGD conjugate for anti-anigiogenesis. J. Contolled Release 106, 224-234.
23. Suh, W., Han, S. O., Yu, L., and Kim, S. W. (2002) An anigiogenetic, endothelial-cell-targeted polymeric gene canier. Mol. Ther. 6, 664-672.
24. Klaus, K., Merdan, T., Hegener, O., Haberlein, H., and Kissel, T. (2003) Integrin targeting using RGD-PEI conjugates for in vitro gene transfer. J. Gene Med. 5, 588-599.
25. Ruoslahti, E., and Reed, J. C. (1994) Anchorage dependence, integrins and apotosis. Cell 77, 477-478.
26. Damsky, C. H., and Werb, Z. (1992) Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information. Curr. Opin. Cell Biol. 5, 864-868.