메뉴 건너뛰기




Volumn 131, Issue 3, 2008, Pages 616-629

Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke

Author keywords

Cerebral inflammation; Intracerebral haemorrhage; Macrophage; Neural stem cell; Spleen

Indexed keywords

CASPASE 3; COLLAGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 39749109431     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awm306     Document Type: Article
Times cited : (380)

References (69)
  • 1
    • 0035487313 scopus 로고    scopus 로고
    • Cytokines and acute neurodegeneration
    • Allan SM, Rothwell NJ. Cytokines and acute neurodegeneration. Nat Rev Neurosci 2001; 2: 734-44.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 734-744
    • Allan, S.M.1    Rothwell, N.J.2
  • 2
    • 17144403822 scopus 로고    scopus 로고
    • New horizons for primary intracerebral hemorrhage treatment: Experience from preclinical studies
    • Aronowski J, Hall CE. New horizons for primary intracerebral hemorrhage treatment: experience from preclinical studies. Neurol Res 2005; 27: 268-79.
    • (2005) Neurol Res , vol.27 , pp. 268-279
    • Aronowski, J.1    Hall, C.E.2
  • 3
    • 0033638508 scopus 로고    scopus 로고
    • Role for matrix metalloproteinase 9 after focal cerebral ischemia: Effects of gene knockout and enzyme inhibition with BB-94
    • Asahi M, Asahi K, Jung JC, del Zoppo GJ, Fini ME, Lo EH. Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94. J Cereb Blood Flow Metab 2000; 20: 1681-9.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1681-1689
    • Asahi, M.1    Asahi, K.2    Jung, J.C.3    del Zoppo, G.J.4    Fini, M.E.5    Lo, E.H.6
  • 4
    • 18444373622 scopus 로고    scopus 로고
    • Immune problems in central nervous system cell therapy
    • Barker RA, Widner H. Immune problems in central nervous system cell therapy. NeuroRx 2004; 1: 472-81.
    • (2004) NeuroRx , vol.1 , pp. 472-481
    • Barker, R.A.1    Widner, H.2
  • 5
    • 0033512004 scopus 로고    scopus 로고
    • Inflammatory mediators and stroke: New opportunities for novel therapeutics
    • Barone FC, Feuerstein GZ. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J Cereb Blood Flow Metab 1999; 19: 819-34.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 819-834
    • Barone, F.C.1    Feuerstein, G.Z.2
  • 7
    • 33947515643 scopus 로고    scopus 로고
    • Infection after acute ischemic stroke: A manifestation of brain-induced immunodepression
    • Chamorro A, Urra X, Planas AM. Infection after acute ischemic stroke: a manifestation of brain-induced immunodepression. Stroke 2007; 38: 1097-103.
    • (2007) Stroke , vol.38 , pp. 1097-1103
    • Chamorro, A.1    Urra, X.2    Planas, A.M.3
  • 8
    • 0030710120 scopus 로고    scopus 로고
    • Use of a spectrophotometric hemoglobin assay to objectively quantify intracerebral hemorrhage in mice
    • Choudhri TF, Hoh BL, Solomon RA, Connolly ES, Jr., Pinsky DJ. Use of a spectrophotometric hemoglobin assay to objectively quantify intracerebral hemorrhage in mice. Stroke 1997; 28: 2296-302.
    • (1997) Stroke , vol.28 , pp. 2296-2302
    • Choudhri, T.F.1    Hoh, B.L.2    Solomon, R.A.3    Connolly Jr., E.S.4    Pinsky, D.J.5
  • 9
    • 3843082003 scopus 로고    scopus 로고
    • Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death
    • Chu K, Jeong SW, Jung KH, Han SY, Lee ST, Kim M, et al. Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. J Cereb Blood Flow Metab 2004a; 24: 926-33.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 926-933
    • Chu, K.1    Jeong, S.W.2    Jung, K.H.3    Han, S.Y.4    Lee, S.T.5    Kim, M.6
  • 10
    • 9644275392 scopus 로고    scopus 로고
    • Distribution and in situ proliferation patterns of intravenously injected immortalized human neural stem-like cells in rats with focal cerebral ischemia
    • Chu K, Kim M, Chae SH, Jeong SW, Kang KS, Jung KH, et al. Distribution and in situ proliferation patterns of intravenously injected immortalized human neural stem-like cells in rats with focal cerebral ischemia. Neurosci Res 2004b; 50: 459-65.
    • (2004) Neurosci Res , vol.50 , pp. 459-465
    • Chu, K.1    Kim, M.2    Chae, S.H.3    Jeong, S.W.4    Kang, K.S.5    Jung, K.H.6
  • 11
    • 4544290431 scopus 로고    scopus 로고
    • Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats
    • Chu K, Kim M, Jung KH, Jeon D, Lee ST, Kim J, et al. Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats. Brain Res 2004c; 1023: 213-21.
    • (2004) Brain Res , vol.1023 , pp. 213-221
    • Chu, K.1    Kim, M.2    Jung, K.H.3    Jeon, D.4    Lee, S.T.5    Kim, J.6
  • 12
    • 27844472057 scopus 로고    scopus 로고
    • Combined treatment of vascular endothelial growth factor and human neural stem cells in experimental focal cerebral ischemia
    • Chu K, Park KI, Lee ST, Jung KH, Ko SY, Kang L, et al. Combined treatment of vascular endothelial growth factor and human neural stem cells in experimental focal cerebral ischemia. Neurosci Res 2005; 53: 384-90.
    • (2005) Neurosci Res , vol.53 , pp. 384-390
    • Chu, K.1    Park, K.I.2    Lee, S.T.3    Jung, K.H.4    Ko, S.Y.5    Kang, L.6
  • 13
    • 3042773051 scopus 로고    scopus 로고
    • Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia
    • Chu K, Kim M, Park KI, Jeong SW, Park HK, Jung KH, et al. Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia. Brain Res 2004d; 1016: 145-53.
    • (2004) Brain Res , vol.1016 , pp. 145-153
    • Chu, K.1    Kim, M.2    Park, K.I.3    Jeong, S.W.4    Park, H.K.5    Jung, K.H.6
  • 14
    • 0030482414 scopus 로고    scopus 로고
    • Experimental intracerebral hemorrhage in rats. Magnetic resonance imaging and histopathological correlates
    • Del Bigio MR, Yan HJ, Buist R, Peeling J. Experimental intracerebral hemorrhage in rats. Magnetic resonance imaging and histopathological correlates. Stroke 1996; 27: 2312-20.
    • (1996) Stroke , vol.27 , pp. 2312-2320
    • Del Bigio, M.R.1    Yan, H.J.2    Buist, R.3    Peeling, J.4
  • 15
    • 33846583388 scopus 로고    scopus 로고
    • Stroke-induced immunodepression: Experimental evidence and clinical relevance
    • Dirnagl U, Klehmet J, Braun JS, Harms H, Meisel C, Ziemssen T, et al. Stroke-induced immunodepression: experimental evidence and clinical relevance. Stroke 2007; 38: 770-3.
    • (2007) Stroke , vol.38 , pp. 770-773
    • Dirnagl, U.1    Klehmet, J.2    Braun, J.S.3    Harms, H.4    Meisel, C.5    Ziemssen, T.6
  • 17
    • 0023771006 scopus 로고    scopus 로고
    • Acetyl-LDL stimulates macrophage-dependent plasminogen activation and degradation of extracellular matrix
    • Falcone DJ, Ferenc MJ. Acetyl-LDL stimulates macrophage-dependent plasminogen activation and degradation of extracellular matrix. J Cell Physiol 1998; 135: 387-96.
    • (1998) J Cell Physiol , vol.135 , pp. 387-396
    • Falcone, D.J.1    Ferenc, M.J.2
  • 18
    • 3543126057 scopus 로고    scopus 로고
    • Intravenously injected neural progenitor cells of transgenic rats can migrate to the injured spinal cord and differentiate into neurons, astrocytes and oligodendrocytes
    • Fujiwara Y, Tanaka N, Ishida O, Fujimoto Y, Murakami T, Kajihara H, et al. Intravenously injected neural progenitor cells of transgenic rats can migrate to the injured spinal cord and differentiate into neurons, astrocytes and oligodendrocytes. Neurosci Lett 2004; 366: 287-91.
    • (2004) Neurosci Lett , vol.366 , pp. 287-291
    • Fujiwara, Y.1    Tanaka, N.2    Ishida, O.3    Fujimoto, Y.4    Murakami, T.5    Kajihara, H.6
  • 19
    • 34147126415 scopus 로고    scopus 로고
    • Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis
    • Gerdoni E, Gallo B, Casazza S, Musio S, Bonanni I, Pedemonte E, et al. Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis. Ann Neurol 2007; 61: 219-27.
    • (2007) Ann Neurol , vol.61 , pp. 219-227
    • Gerdoni, E.1    Gallo, B.2    Casazza, S.3    Musio, S.4    Bonanni, I.5    Pedemonte, E.6
  • 20
    • 0033976487 scopus 로고    scopus 로고
    • Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice
    • Gregersen R, Lambertsen K, Finsen B. Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice. J Cereb Blood Flow Metab 2000; 20: 53-65.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 53-65
    • Gregersen, R.1    Lambertsen, K.2    Finsen, B.3
  • 21
  • 22
    • 24744440988 scopus 로고    scopus 로고
    • Immunology of ischemic vascular disease: Plaque to attack
    • Hallenbeck JM, Hansson GK, Becker KJ. Immunology of ischemic vascular disease: plaque to attack. Trends Immunol 2005; 26: 550-6.
    • (2005) Trends Immunol , vol.26 , pp. 550-556
    • Hallenbeck, J.M.1    Hansson, G.K.2    Becker, K.J.3
  • 23
    • 33745187411 scopus 로고    scopus 로고
    • Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat
    • Honma T, Honmou O, Iihoshi S, Harada K, Houkin K, Hamada H, et al. Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Exp Neurol 2006; 199: 56-66.
    • (2006) Exp Neurol , vol.199 , pp. 56-66
    • Honma, T.1    Honmou, O.2    Iihoshi, S.3    Harada, K.4    Houkin, K.5    Hamada, H.6
  • 24
    • 23044462502 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha neutralization reduced cerebral edema through inhibition of matrix metalloproteinase production after transient focal cerebral ischemia
    • Hosomi N, Ban CR, Naya T, Takahashi T, Guo P, Song XY, et al. Tumor necrosis factor-alpha neutralization reduced cerebral edema through inhibition of matrix metalloproteinase production after transient focal cerebral ischemia. J Cereb Blood Flow Metab 2005; 25: 959-67.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 959-967
    • Hosomi, N.1    Ban, C.R.2    Naya, T.3    Takahashi, T.4    Guo, P.5    Song, X.Y.6
  • 25
    • 33745830175 scopus 로고    scopus 로고
    • Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis
    • Huston JM, Ochani M, Rosas-Ballina M, Liao H, Ochani K, Pavlov VA, et al. Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. J Exp Med 2006; 203: 1623-8.
    • (2006) J Exp Med , vol.203 , pp. 1623-1628
    • Huston, J.M.1    Ochani, M.2    Rosas-Ballina, M.3    Liao, H.4    Ochani, K.5    Pavlov, V.A.6
  • 26
    • 19944426191 scopus 로고    scopus 로고
    • Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway
    • Imitola J, Raddassi K, Park KI, Mueller FJ, Nieto M, Teng YD, et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci USA 2004; 101: 18117-22.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 18117-18122
    • Imitola, J.1    Raddassi, K.2    Park, K.I.3    Mueller, F.J.4    Nieto, M.5    Teng, Y.D.6
  • 27
    • 0042919307 scopus 로고    scopus 로고
    • Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage
    • Jeong SW, Chu K, Jung KH, Kim SU, Kim M, Roh JK. Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage. Stroke 2003; 34: 2258-63.
    • (2003) Stroke , vol.34 , pp. 2258-2263
    • Jeong, S.W.1    Chu, K.2    Jung, K.H.3    Kim, S.U.4    Kim, M.5    Roh, J.K.6
  • 28
    • 15944397267 scopus 로고    scopus 로고
    • Comparison of ischemia-directed migration of neural precursor cells after intrastriatal, intraventricular, or intravenous transplantation in the rat
    • Jin K, Sun Y, Xie L, Mao XO, Childs J, Peel A, et al. Comparison of ischemia-directed migration of neural precursor cells after intrastriatal, intraventricular, or intravenous transplantation in the rat. Neurobiol Dis 2005; 18: 366-74.
    • (2005) Neurobiol Dis , vol.18 , pp. 366-374
    • Jin, K.1    Sun, Y.2    Xie, L.3    Mao, X.O.4    Childs, J.5    Peel, A.6
  • 29
    • 3042688440 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor, atorvastatin, promotes sensorimotor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage
    • Jung KH, Chu K, Jeong SW, Han SY, Lee ST, Kim JY, et al. HMG-CoA reductase inhibitor, atorvastatin, promotes sensorimotor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage. Stroke 2004; 35: 1744-9.
    • (2004) Stroke , vol.35 , pp. 1744-1749
    • Jung, K.H.1    Chu, K.2    Jeong, S.W.3    Han, S.Y.4    Lee, S.T.5    Kim, J.Y.6
  • 30
    • 4143071470 scopus 로고    scopus 로고
    • Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex
    • Kelly S, Bliss TM, Shah AK, Sun GH, Ma M, Foo WC, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc Natl Acad Sci USA 2004; 101: 11839-44.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11839-11844
    • Kelly, S.1    Bliss, T.M.2    Shah, A.K.3    Sun, G.H.4    Ma, M.5    Foo, W.C.6
  • 31
    • 0028232028 scopus 로고
    • FGF and EGF are mitogens for immortalized neural progenitors
    • Kitchens DL, Snyder EY, Gottlieb DI. FGF and EGF are mitogens for immortalized neural progenitors. J Neurobiol 1994; 25: 797-807.
    • (1994) J Neurobiol , vol.25 , pp. 797-807
    • Kitchens, D.L.1    Snyder, E.Y.2    Gottlieb, D.I.3
  • 32
    • 0036370325 scopus 로고    scopus 로고
    • Hemorrhagic transformation following ischemic stroke: Significance, causes, and relationship to therapy and treatment
    • Lapchak PA. Hemorrhagic transformation following ischemic stroke: significance, causes, and relationship to therapy and treatment. Curr Neurol Neurosci Rep 2002; 2: 38-43.
    • (2002) Curr Neurol Neurosci Rep , vol.2 , pp. 38-43
    • Lapchak, P.A.1
  • 33
    • 20144381234 scopus 로고    scopus 로고
    • Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model
    • Lee ST, Chu K, Park JE, Lee K, Kang L, Kim SU, et al. Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model. Neurosci Res 2005; 52: 243-9.
    • (2005) Neurosci Res , vol.52 , pp. 243-249
    • Lee, S.T.1    Chu, K.2    Park, J.E.3    Lee, K.4    Kang, L.5    Kim, S.U.6
  • 34
    • 33644780840 scopus 로고    scopus 로고
    • Noninvasive method of immortalized neural stem-like cell transplantation in an experimental model of Huntington's disease
    • Lee ST, Park JE, Lee K, Kang L, Chu K, Kim SU, et al. Noninvasive method of immortalized neural stem-like cell transplantation in an experimental model of Huntington's disease. J Neurosci Methods 2006a; 152: 250-4.
    • (2006) J Neurosci Methods , vol.152 , pp. 250-254
    • Lee, S.T.1    Park, J.E.2    Lee, K.3    Kang, L.4    Chu, K.5    Kim, S.U.6
  • 35
    • 33644810653 scopus 로고    scopus 로고
    • Memantine reduces hematoma expansion in experimental intracerebral hemorrhage, resulting in functional improvement
    • Lee ST, Chu K, Jung KH, Kim J, Kim EH, Kim SJ, et al. Memantine reduces hematoma expansion in experimental intracerebral hemorrhage, resulting in functional improvement. J Cereb Blood Flow Metab 2006b; 26: 536-44.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 536-544
    • Lee, S.T.1    Chu, K.2    Jung, K.H.3    Kim, J.4    Kim, E.H.5    Kim, S.J.6
  • 36
    • 33748308798 scopus 로고    scopus 로고
    • Quantification of human neural stem cell engraftments in rat brains using ERV-3 real-time PCR
    • Lee ST, Chu K, Kim EH, Jung KH, Lee KB, Sinn DI, et al. Quantification of human neural stem cell engraftments in rat brains using ERV-3 real-time PCR. J Neurosci Methods 2006c; 157: 225-9.
    • (2006) J Neurosci Methods , vol.157 , pp. 225-229
    • Lee, S.T.1    Chu, K.2    Kim, E.H.3    Jung, K.H.4    Lee, K.B.5    Sinn, D.I.6
  • 37
    • 33644791801 scopus 로고    scopus 로고
    • Erythropoietin reduces perihematomal inflammation and cell death with eNOS and STAT3 activations in experimental intracerebral hemorrhage
    • Lee ST, Chu K, Sinn DI, Jung KH, Kim EH, Kim SJ, et al. Erythropoietin reduces perihematomal inflammation and cell death with eNOS and STAT3 activations in experimental intracerebral hemorrhage. J Neurochem 2006d; 96: 1728-39.
    • (2006) J Neurochem , vol.96 , pp. 1728-1739
    • Lee, S.T.1    Chu, K.2    Sinn, D.I.3    Jung, K.H.4    Kim, E.H.5    Kim, S.J.6
  • 38
    • 33745684551 scopus 로고    scopus 로고
    • The therapeutic potential of neural stem cells
    • Martino G, Pluchino S. The therapeutic potential of neural stem cells. Nat Rev Neurosci 2006; 7: 395-406.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 395-406
    • Martino, G.1    Pluchino, S.2
  • 40
    • 23444437972 scopus 로고    scopus 로고
    • Structure and function of the spleen
    • Mebius RE, Kraal G. Structure and function of the spleen. Nat Rev Immunol 2005; 5: 606-16.
    • (2005) Nat Rev Immunol , vol.5 , pp. 606-616
    • Mebius, R.E.1    Kraal, G.2
  • 42
    • 34147093698 scopus 로고    scopus 로고
    • The expanding influence of stem cells in neural repair
    • Miller RH, Bai L. The expanding influence of stem cells in neural repair. Ann Neurol 2007; 61: 187-8.
    • (2007) Ann Neurol , vol.61 , pp. 187-188
    • Miller, R.H.1    Bai, L.2
  • 43
    • 33745613239 scopus 로고    scopus 로고
    • The promise of stem cells for neural repair
    • Miller RH. The promise of stem cells for neural repair. Brain Res 2006; 1091: 258-64.
    • (2006) Brain Res , vol.1091 , pp. 258-264
    • Miller, R.H.1
  • 44
    • 33750569566 scopus 로고    scopus 로고
    • Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins
    • Mueller FJ, Serobyan N, Schraufstatter IU, DiScipio R, Wakeman D, Loring JF, et al. Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins. Stem Cells 2006; 24: 2367-72.
    • (2006) Stem Cells , vol.24 , pp. 2367-2372
    • Mueller, F.J.1    Serobyan, N.2    Schraufstatter, I.U.3    DiScipio, R.4    Wakeman, D.5    Loring, J.F.6
  • 45
    • 26944484409 scopus 로고    scopus 로고
    • Nomura T, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD. I.V. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Neuroscience 2005; 136: 161-9.
    • Nomura T, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD. I.V. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Neuroscience 2005; 136: 161-9.
  • 47
    • 0036844019 scopus 로고    scopus 로고
    • Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons
    • Ourednik J, Ourednik V, Lynch WP, Schachner M, Snyder EY. Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons. Nat Biotechnol 2002; 20: 1103-10.
    • (2002) Nat Biotechnol , vol.20 , pp. 1103-1110
    • Ourednik, J.1    Ourednik, V.2    Lynch, W.P.3    Schachner, M.4    Snyder, E.Y.5
  • 48
    • 0035823130 scopus 로고    scopus 로고
    • Segregation of human neural stem cells in the developing primate forebrain
    • Ourednik V, Ourednik J, Flax JD, Zawada WM, Hutt C, Yang C, et al. Segregation of human neural stem cells in the developing primate forebrain. Science 2001; 293: 1820-4.
    • (2001) Science , vol.293 , pp. 1820-1824
    • Ourednik, V.1    Ourednik, J.2    Flax, J.D.3    Zawada, W.M.4    Hutt, C.5    Yang, C.6
  • 50
    • 22444450988 scopus 로고    scopus 로고
    • Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
    • Pluchino S, Zanotti L, Rossi B, Brambilla E, Ottoboni L, Salani G, et al. Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature 2005; 436: 266-71.
    • (2005) Nature , vol.436 , pp. 266-271
    • Pluchino, S.1    Zanotti, L.2    Rossi, B.3    Brambilla, E.4    Ottoboni, L.5    Salani, G.6
  • 51
    • 84979726329 scopus 로고    scopus 로고
    • Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
    • Pluchino S, Quattrini A, Brambilla E, Gritti A, Salani G, Dina G, et al. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 2003; 422: 688-94.
    • (2003) Nature , vol.422 , pp. 688-694
    • Pluchino, S.1    Quattrini, A.2    Brambilla, E.3    Gritti, A.4    Salani, G.5    Dina, G.6
  • 52
    • 0042886941 scopus 로고    scopus 로고
    • Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation
    • Prass K, Meisel C, Hoflich C, Braun J, Halle E, Wolf T, et al. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med 2003; 198: 725-36.
    • (2003) J Exp Med , vol.198 , pp. 725-736
    • Prass, K.1    Meisel, C.2    Hoflich, C.3    Braun, J.4    Halle, E.5    Wolf, T.6
  • 53
    • 0034852360 scopus 로고    scopus 로고
    • A crucial role for CD44 in inflammation
    • Pure E, Cuff CA. A crucial role for CD44 in inflammation. Trends Mol Med 2001; 7: 213-21.
    • (2001) Trends Mol Med , vol.7 , pp. 213-221
    • Pure, E.1    Cuff, C.A.2
  • 55
    • 13844253258 scopus 로고    scopus 로고
    • Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons
    • Schmued LC, Stowers CC, Scallet AC, Xu L. Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons. Brain Res 2005; 1035: 24-31.
    • (2005) Brain Res , vol.1035 , pp. 24-31
    • Schmued, L.C.1    Stowers, C.C.2    Scallet, A.C.3    Xu, L.4
  • 56
    • 2542626091 scopus 로고    scopus 로고
    • Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells
    • Shen Q, Goderie SK, Jin L, Karanth N, Sun Y, Abramova N, et al. Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 2004; 304: 1338-40.
    • (2004) Science , vol.304 , pp. 1338-1340
    • Shen, Q.1    Goderie, S.K.2    Jin, L.3    Karanth, N.4    Sun, Y.5    Abramova, N.6
  • 57
    • 33748990080 scopus 로고    scopus 로고
    • Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology
    • Singec I, Knoth R, Meyer RP, Maciaczyk J, Volk B, Nikkhah G, et al. Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology. Nat Methods 2006; 3: 801-6.
    • (2006) Nat Methods , vol.3 , pp. 801-806
    • Singec, I.1    Knoth, R.2    Meyer, R.P.3    Maciaczyk, J.4    Volk, B.5    Nikkhah, G.6
  • 58
    • 34147199586 scopus 로고    scopus 로고
    • Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation
    • Sinn DI, Kim SJ, Chu K, Jung KH, Lee ST, Song EC, et al. Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation. Neurobiol Dis 2007; 26: 464-72.
    • (2007) Neurobiol Dis , vol.26 , pp. 464-472
    • Sinn, D.I.1    Kim, S.J.2    Chu, K.3    Jung, K.H.4    Lee, S.T.5    Song, E.C.6
  • 59
    • 0030881885 scopus 로고    scopus 로고
    • Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex
    • Snyder EY, Yoon C, Flax JD, Macklis JD. Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex. Proc Natl Acad Sci USA 1997; 94: 11663-8.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11663-11668
    • Snyder, E.Y.1    Yoon, C.2    Flax, J.D.3    Macklis, J.D.4
  • 60
    • 0037023216 scopus 로고    scopus 로고
    • The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice
    • Stevens SL, Bao J, Hollis J, Lessov NS, Clark WM, Stenzel-Poore MP. The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice. Brain Res 2002; 932: 110-9.
    • (2002) Brain Res , vol.932 , pp. 110-119
    • Stevens, S.L.1    Bao, J.2    Hollis, J.3    Lessov, N.S.4    Clark, W.M.5    Stenzel-Poore, M.P.6
  • 61
    • 4043052443 scopus 로고    scopus 로고
    • Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model
    • Taguchi A, Soma T, Tanaka H, Kanda T, Nishimura H, Yoshikawa H, et al. Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J Clin Invest 2004; 114: 330-8.
    • (2004) J Clin Invest , vol.114 , pp. 330-338
    • Taguchi, A.1    Soma, T.2    Tanaka, H.3    Kanda, T.4    Nishimura, H.5    Yoshikawa, H.6
  • 62
    • 0035843995 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms in the vascular wall
    • Tedgui A, Mallat Z. Anti-inflammatory mechanisms in the vascular wall. Circ Res 2001; 88: 877-87.
    • (2001) Circ Res , vol.88 , pp. 877-887
    • Tedgui, A.1    Mallat, Z.2
  • 63
    • 33846817498 scopus 로고    scopus 로고
    • Physiology and immunology of the cholinergic antiinflammatory pathway
    • Tracey KJ. Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest 2007; 117: 289-96.
    • (2007) J Clin Invest , vol.117 , pp. 289-296
    • Tracey, K.J.1
  • 64
    • 0037335934 scopus 로고    scopus 로고
    • Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke
    • Vila N, Castillo J, Dávalos A, Esteve A, Planas AM, Chamorro A. Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke. Stroke 2003; 34: 671-5.
    • (2003) Stroke , vol.34 , pp. 671-675
    • Vila, N.1    Castillo, J.2    Dávalos, A.3    Esteve, A.4    Planas, A.M.5    Chamorro, A.6
  • 65
    • 34247488271 scopus 로고    scopus 로고
    • Inflammation after intracerebral hemorrhage
    • Wang J, Dore S. Inflammation after intracerebral hemorrhage. J Cereb Blood Flow Metab 2007; 27: 894-908.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 894-908
    • Wang, J.1    Dore, S.2
  • 66
    • 14844329885 scopus 로고    scopus 로고
    • Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage
    • Wang J, Tsirka SE. Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage. Stroke 2005; 36: 613-8.
    • (2005) Stroke , vol.36 , pp. 613-618
    • Wang, J.1    Tsirka, S.E.2
  • 67
    • 29044441975 scopus 로고    scopus 로고
    • Mechanisms of brain injury after intracerebral haemorrhage
    • Xi G, Keep RF, Hoff JT. Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol 2006; 5: 53-63.
    • (2006) Lancet Neurol , vol.5 , pp. 53-63
    • Xi, G.1    Keep, R.F.2    Hoff, J.T.3
  • 68
    • 23944519424 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
    • Zappia E, Casazza S, Pedemonte E, Benvenuto F, Bonanni I, Gerdoni E, et al. Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy. Blood 2005; 106: 1755-61.
    • (2005) Blood , vol.106 , pp. 1755-1761
    • Zappia, E.1    Casazza, S.2    Pedemonte, E.3    Benvenuto, F.4    Bonanni, I.5    Gerdoni, E.6
  • 69
    • 10344229430 scopus 로고    scopus 로고
    • Post-ischemic inflammation: Molecular mechanisms and therapeutic implications
    • Zheng Z, Yenari MA. Post-ischemic inflammation: molecular mechanisms and therapeutic implications. Neurol Res 2004; 26: 884-92.
    • (2004) Neurol Res , vol.26 , pp. 884-892
    • Zheng, Z.1    Yenari, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.