VEGF polymorphisms and survival in early-stage non-small-cell lung cancer

Journal of Clinical Oncology

Volumn 26, Issue 6, 2008, Pages 856-862

  Heist, Rebecca Suk ^a   Zhai, Rihong ^a   Liu, Geoffrey ^a   Zhou, Wei ^a   Lin, Xihong ^a   Su, Li ^a   Asomaning, Kofi ^a   Lynch, Thomas J ^a   Wain, John C ^a   Christiani, David C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; VASCULOTROPIN; VASCULOTROPIN A;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; FOLLOW UP; GENE FREQUENCY; GENOTYPE; HUMAN; LOBECTOMY; LUNG NON SMALL CELL CANCER; LUNG RESECTION; LUNG SURGERY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; SMOKING; SURVIVAL; CANCER STAGING; GENETIC POLYMORPHISM; GENETICS; KAPLAN MEIER METHOD; LUNG TUMOR; MIDDLE AGED; PATHOLOGY; PROPORTIONAL HAZARDS MODEL;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; GENE FREQUENCY; HUMANS; KAPLAN-MEIERS ESTIMATE; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; POLYMORPHISM, GENETIC; PROPORTIONAL HAZARDS MODELS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 39749096242     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2007.13.5947     Document Type: Article

References (30)

1. Carmeliet P, Jain RK: Angiogenesis in cancer and other diseases. Nature 407:249-257, 2000
2. Jain RK: Tumor angiogenesis and accessibility: Role of vascular endothelial growth factor. Semin Oncol 29:3-9, 2002 (suppl 16)
3. Ferrara N, Alitalo K: Clinical applications of angiogenic growth factors and their inhibitors. Nat Med 5:1359-1364, 1999
4. Asano M, Yukita A, Matsumoto T, et al: Inhibition of tumor-growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor vascular permeability factor. Cancer Res 55:5296-5301, 1995
5. Kim KJ, Li B, Winer J, et al: Inhibition of vascular endothelial growth factor induced angiogenesis suppresses tumor growth in vivo. Nature 362:841-844, 1993
6. Stefanou D, Goussia AC, Arkoumani E, et al: Expression of vascular endothelial growth factor and the adhesion molecule E-cadherin in non-small cell lung cancer. Anticancer Res 23:4715-4720, 2003
7. Oshika Y, Nakamura M, Tokunaga T, et al: Expression of cell-associated isoform of vascular endothelial growth factor 189 and its prognostic relevance in non-small cell lung cancer. Int J Oncol 12:541-544, 1998
8. Fontanini GM, Mussi A, Angeletti CA, et al: Expression of vascular endothelial growth factor mRNA in non-small cell lung carcinomas. Br J Cancer 79:363-369, 1999
9. O'Bryne KJ, Koukourakis MI, Giatromanolaki A, et al: Vascular endothelial growth factor, platelet-derived endothelial growth factor and angiogenesis in non-small cell lung cancer. Br J Cancer 82:1427-1432, 2000
10. Fontanini G, Lucchi M, Vignati S, et al: Angiogenesis as a prognostic indicator of survival in non-small cell lung carcinoma: A prospective study. J Natl Cancer Inst 89:881-886, 1997
11. Yuan A, Yu CJ, Kuo SH, et al: Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small cell lung cancer. J Clin Oncol 19:432-441, 2001
12. Han H, Silverman JF, Santucci TS, et al: Vascular endothelial growth factor expression in stage I non-small cell lung cancer correlates with neoangiogenesis and a poor prognosis. Ann Surg Oncol 8:72-79, 2001
13. Renner W, Kotschan S, Hoffman C, et al: A common 936 C/T mutation in the gene for vascular endothelial growth factor is associated with vascular endothelial growth factor plasma levels. J Vasc Res 37:443-448, 2000
14. Zhai R, Gong MN, Thompson TB, et al: Genotypes and haplotypes of VEGF gene are associated with higher ARDS mortality and lower VEGF plasma levels. Thorax 62:718-722, 2007
15. Stevens A, Soden J, Brenchely PE, et al: Haplotype analysis of the polymorphic human vascular endothelial growth factor gene promoter. Cancer Res 63:812-816, 2003
16. Watson CJ, Webb NJA, Bottomley MJ, et al: Identification of polymorphisms within the vascular endothelial growth factor (VEGF) gene: Correlation with variation in VEGF protein production. Cytokine 12:1232-1235, 2000
17. Awata T, Inoue K, Kurihara S, et al: A common polymorphism in the 5′ untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes. Diabetes 51:1635-1639, 2002
18. Balasubramanian SP, Cox A, Cross SS, et al: Influence of VEGF-A gene variation and protein levels in breast cancer susceptibility and severity. Int J Cancer 121:1009-1016, 2007
19. Krippl P, Langsenlehner U, Renner W, et al: A common 936 C/T gene polymorphism of vascular endothelial growth factor is associated with decreased breast cancer risk. Int J Cancer 106:468-471, 2003
20. Kataoka N, Cai Q, Wen W, et al: Population based case control study of VEGF gene polymorphisms and breast cancer risk among Chinese women. Cancer Epidemiol Biomarkers Prev 15:1148-1152, 2006
21. Jin Q, Hemminki K, Enquist K, et al: Vascular endothelial growth factor polymorphisms in relation to breast cancer development and prognosis. Clin Cancer Res 11:3647-3653, 2005
22. Jacobs EJ, Feigelson HS, Bain EB, et al: Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort. Breast Cancer Res 8:R22, 2006
23. Howell WM, Bateman AC, Turner SJ, et al: Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma. Genes Immun 3:229-232, 2002
24. Sfar S, Hassen E, Saad H, et al: Association of VEGF genetic polymorphisms with prostage cancer risk and clinical outcome. Cytokine 35:21-28, 2006
25. Reference deleted
26. Tzanakis N, Gazouli M, Rallis G, et al: Vascular endothelial growth factor polymorphisms in gastric cancer development, prognosis, and survival. J Surg Oncol 94:624-630, 2006
27. Hefler LA, Mustea A, Konsgen D, et al: Vascular endothelial growth factor polymorphisms are associated with prognosis in ovarian cancer. Clin Cancer Res 13:898-901, 2007
28. Lu H, Shu XO, Kataoka N, et al: Association of genetic polymorphisms in the VEGF gene and breast cancer survival. Cancer Res 65:5015-5019, 2005
29. Lurje G, Schultheis AM, Hendifar AE, et al: VEGF and VEGFR2 gene polymorphisms predict tumor recurrence in stage II and III colon cancer. J Clin Oncol 25:164s, 2007 (suppl; abstr 4004)
30. Hanahan D, Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86:353-364, 1996