TNF-α alters nitric oxide- and endothelium-derived hyperpolarizing factor-mediated vasodilatation in human omental arteries

Hypertension in Pregnancy

Volumn 27, Issue 1, 2008, Pages 29-38

  Gillham, J C ^a   Myers, J E ^a,b   Baker, P N ^a   Taggart, M J ^a,b  

^a ST MARY S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

EDHF; Endothelium; Human pregnancy; Myography; TNF

Indexed keywords

BRADYKININ; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; NITRIC OXIDE; POTASSIUM; PROSTACYCLIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTERY DILATATION; ARTICLE; CESAREAN SECTION; CONTROLLED STUDY; ENDOTHELIUM; FEMALE; HUMAN; HUMAN TISSUE; MYOGRAPHY; NORMAL HUMAN; OMENTUM; PREGNANCY; PREGNANT WOMAN; VASOCONSTRICTION; VASODILATATION;

ADULT; ARTERIES; BIOLOGICAL FACTORS; BRADYKININ; ENDOTHELIUM, VASCULAR; EPOPROSTENOL; FEMALE; HUMANS; NITRIC OXIDE; OMENTUM; TUMOR NECROSIS FACTOR-ALPHA; VASODILATION;

EID: 39749083252     PISSN: 10641955     EISSN: 15256065     Source Type: Journal    
DOI: 10.1080/10641950701825796     Document Type: Article

References (28)

1. Bunting S, Gryglewski R, Moncada S, Vane JR. Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac ateries and inhibits platelet aggregation. Prostaglandins 1976;12:897-913.
2. Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-526.
3. Edwards G, Dora KA, Gardener MJ, Garland CJ, Weston AH. K+ is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 1998;396:269-272.
4. Hecker M, Bara AT, Bauersachs J, Busse R. Characterization of endothelium-derived hyperpolarizing factor as a cytochrome P450-derived arachidonic acid metabolite in mammals. J Physiol 1994;481(Pt 2):407-414.
5. Randall MD, Alexander SP, Bennett T, Boyd EA, Fry JR, Gardiner SM, et al. An endogenous cannabinoid as an endothelium-derived vasorelaxant. Biochem Biophys Res Commun 1996;229:114-1120.
6. Harris D, Martin PE, Evans WH, Kendall DA, Griffith TM, Randall MD. Role of gap junctions in endothelium-derived hyperpolarizing factor responses and mechanisms of K(+)-relaxation. Eur J Pharmacol 2000;402:119-128.
7. Dora KA, Sandow SL, Gallagher NT, Takano H, Rummery NM, Hill CE, et al. Myoendothelial gap junctions may provide the pathway for EDHF in mouse mesenteric artery. J Vasc Res 2003;40:480-490.
8. Gerber RT, Anwar MA, Poston L. Enhanced acetylcholine induced relaxation in small mesenteric arteries from pregnant rats: an important role for endothelium-derived hyperpolarizing factor (EDHF). Br J Pharmacol 1998;125:455-460.
9. Ashworth JR, Baker PN, Warren AY, Johnson IR. Mechanisms of endothelium-dependent relaxation in myometrial resistance vessels and their alteration in preeclampsia. Hypertens Pregnancy 1999;18:57-71.
10. Kenny LC, Baker PN, Kendall DA, Randall MD, Dunn WR. Differential mechanisms of endothelium-dependent vasodilator responses in human myometrial small arteries in normal pregnancy and pre-eclampsia. Clin Sci (Lond) 2002;103:67-73.
11. Suzuki Y, Hattori T, Kajikuri J, Yamamoto T, Suzumori K, Itoh T. Reduced function of endothelial prostacyclin in human omental resistance arteries in preeclampsia. J Physiol 2002;545:269-277.
12. Conrad KP, Benyo DF. Placental cytokines and the pathogenesis of preeclampsia. Am J Reprod Immunol 1997;37:240-249.
13. Hamai Y, Fujii T, Yamashita T, Nishina H, Kozuma S, Mikami Y, et al. Evidence for an elevation in serum interleukin-2 and tumor necrosis factor-alpha levels before the clinical manifestations of preeclampsia. Am J Reprod Immunol 1997;38:89-93.
14. Conrad KP, Miles TM, Benyo DF. Circulating levels of immunoreactive cytokines in women with preeclampsia. Am J Reprod Immunol 1998;40:102-111.
15. Nunez-Gonzalez JR, Sanabria-Vera CJ, Romero-Adrian T. [Measurement of the serum concentrations of tumor necrosis factor alpha and its soluble receptors in normal and pre-eclamptic pregnant patients]. Invest Clin 2001;42:171-181.
16. Giardina JB, Green GM, Cockrell KL, Granger JP, Khalil RA. TNF-alpha enhances contraction and inhibits endothelial NO-cGMP relaxation in systemic vessels of pregnant rats. Am J Physiol Regul Integr Comp Physiol 2002;283:R130-R143.
17. Wimalasundera R, Fexby S, Regan L, Thom SA, Hughes AD. Effect of tumour necrosis factor-alpha and interleukin 1beta on endothelium-dependent relaxation in rat mesenteric resistance arteries in vitro. Br J Pharmacol 2003;138:1285-1294.
18. Davis JR, Giardina JB, Green GM, Alexander BT, Granger JP, Khalil RA. Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant rats. Am J Physiol Regul Integr Comp Physiol 2002;282:R390-R399.
19. Nakamura M, Yoshida H, Arakawa N, Saitoh S, Satoh M, Hiramori K. Effects of tumor necrosis factor-alpha on basal and stimulated endothelium-dependent vasomotion in human resistance vessel. J Cardiovasc Pharmacol 2000;36:487-492.
20. Yoshizumi M, Perrella MA, Burnett JC, Jr., Lee ME. Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life. Circ Res 1993;73:205-209.
21. Fernandez-Cobo M, Gingalewski C, Drujan D, De Maio A. Downregulation of connexin 43 gene expression in rat heart during inflammation. The role of tumour necrosis factor. Cytokine 1999;11:216-224.
22. Temme A, Traub O, Willecke K. Downregulation of connexin32 protein and gap-junctional intercellular communication by cytokine-mediated acute-phase response in immortalized mouse hepatocytes. Cell Tissue Res 1998;294:345-350.
23. Wilcox MA, Johnson IR, Maynard PV, Smith SJ, Chilvers CE. The individualised birthweight ratio: a more logical outcome measure of pregnancy than birthweight alone. Br J Obstet Gynaecol 1993;100:342-347.
24. Wareing M, Bhatti H, O'Hara M, Kenny L, Warren AY, Taggart MJ, et al. Vasoactive effects of neurokinin B on human blood vessels. Am J Obstet Gynecol 2003;188:196-202.
25. Lamas S, Michel T, Brenner BM, Marsden PA. Nitric oxide synthesis in endothelial cells: evidence for a pathway inducible by TNF-alpha. Am J Physiol 1991;261:C634-C641.
26. Coleman HA, Tare M, Parkington HC. K+ currents underlying the action of endothelium-derived hyperpolarizing factor in guinea-pig, rat and human blood vessels. J Physiol 2001;531:359-373.
27. van Rijen HV, van Kempen MJ, Postma S, Jongsma HJ. Tumour necrosis factor alpha alters the expression of connexin43, connexin40, and connexin37 in human umbilical vein endothelial cells. Cytokine 1998;10:258-264.
28. Martens FM, Rabelink TJ, op 't Roodt J, de Koning EJ, Visseren FL. TNF-alpha induces endothelial dysfunction in diabetic adults, an effect reversible by the PPAR-gamma agonist pioglitazone. Eur Heart J 2006;27:1605-1609.