Accumulation of cadmium and its effects on testis function in rats given diet containing cadmium-polluted radish bulb

Experimental and Toxicologic Pathology

Volumn 59, Issue 5, 2008, Pages 307-311

  Haouem, Samir ^a   Najjar, Mohamed Fathel ^b   El Hani, Abdelhamid ^a   Sakly, Rachid ^c  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b FATTOUMA BOURGUIBA UNIVERSITY HOSPITAL   (Tunisia)

^c University of Monastir   (Tunisia)

Author keywords

Organic cadmium; Rat; Testis function

Indexed keywords

CADMIUM; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET; DRUG EFFECT; EPIDIDYMIS; HORMONE BLOOD LEVEL; MALE; NONHUMAN; ORGAN WEIGHT; RADISH; RAT; SPERMATOGENESIS; SPERMATOZOON DENSITY; TESTIS FUNCTION;

ANIMALIA; RAPHANUS SATIVUS; RATTUS;

EID: 39649125418     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2007.10.002     Document Type: Article

References (29)

1. Bench G., Corzett M.H., Martinelli R., and Balhorn R. Cadmium concentrations in the testes, sperm, and spermatids of mice subjected to long-term cadmium chloride exposure. Cytometry 35 (1999) 30-36
2. Blanco A., Moyano R., Vivo J., Frores-Acuña R., Molina A., Blanco C., et al. Quantitative changes in the testicular structure in mice exposed to low dose of cadmium. Environ Toxicol Pharmacol 23 (2007) 96-101
3. Caflisch C.R. Effect of orally administered cadmium on in situ pH, PCO2, and bicarbonate concentration in rat testis and epididymis. J Toxicol Environ Health 42 (1994) 323-330
4. Clark J.T., Jimenez B., Evans S.L., Barrow R., Winfree M., and Mrotek J.J. Cadmium-induced sexual dysfunction does not involve increased hepatic metabolism of testosterone nor increased circulating levels of testosterone. Physiol Behav 56 (1994) 975-981
5. Cotzias G.C., Borg D.C., and Selleck B. Virtual absence of turnover in cadmium metabolism: Cd109 studies in the mouse. Am J Physiol 201 (1961) 927-930
6. El-Demardash F.M., Yousef M.I., Kedwany F.S., and Bagdadi H.H. Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and β-carotene. Food Chem Toxicol 42 (2004) 563-571
7. Foote R.H. Cadmium affects testes and semen of rabbits exposed before and after puberty. Reprod Toxicol 13 (1999) 269-277
8. Gorbel F., Boujelbene M., Makni-Ayadi F., Guermazi F., Croute F., Soleilhavoup J.P., et al. Images of lead given in drinking water on the endocrine and exocrine and exocrine sexual activity in pubescent rats. Determination of an apoptotic process. C R Biol 325 (2002) 927-940
9. Gunnarsson D., Nordberg G., Lundgren P., and Selstam G. Cadmium-induced decrement of LH receptor expression and CAMP levels in the testis of rats. Toxicology 183 (2003) 57-63
10. Haouem S., and Sakly R. Lactational transfer of cadmium from Meriones shawi shawi mothers to their pups and its effects on calcium homoeostasis and bone calcium in pups. Ann Nutr Metab 49 (2005) 296-299
11. Jarup L., Berglund M., Elinder C.G., Nordberg G., and Vahter M. Health effect of cadmium-exposure: a review of the literature and a risk estimate. Scand J Environ Health 24 (1998) 7-8
12. Kime D.E. The effect of cadmium on steroidogenesis by testes of the rainbow trout, Salmo gardneri. Toxicol Lett 2 (1982) 83-88
13. Lafuente A., González-Carracedo A., Romero A., Cano P., and Esquifino A.I. Cadmium exposure differentially modifies the circadian patterns of norepinephrine at the median eminence and plasma LH, FSH and testosterone levels. Toxicol Lett 14 (2004) 175-182
14. Lafuente A., Marquez N., Perez-Lorenzo M., Pazo D., and Esquifino A.I. Pubertal and postpubertal cadmium exposure differentially affects the hypothalamic-pituitary-testicular axis function in the rat. Food Chem Toxicol 38 (2000) 913-923
15. Laskey J.W., Rehnberg G.L., Laws S.C., and Hein J.F. Reproductive effects of low acute doses of cadmium chloride in adult male rats. Toxicol Appl Pharmacol 73 (1984) 250-255
16. Nordberg G. Effects of long-term cadmium exposure on the seminal vesicles of mice. J Reprod Fertil 45 (1975) 165-167
17. Nordberg G.F., and Kjellstrom T. Metabolic model for cadmium in man. Environ Health Perspect 28 (1979) 211-217
18. Parizek J. The destructive effect of cadmium ion on testicular tissue and its prevention by zinc. J. Endocrinol 15 (1957) 56-63
19. Ryan J.A., Pahren H.R., and Lucas J.B. Controlling cadmium in the human chain: review and relationale based on health effects. Environ Res 28 (1982) 251-302
20. Santos F.W., Oro T., Zeni G., Rocha J.B., do Nascimento P.C., and Nogueira C.W. Cadmium induced testicular damage and its response to administration of succimer and diphenyl diselenide in mice. Toxicol Lett 152 (2004) 255-263
21. Satarug S., Baker J.R., Urbenjapol S., Haswell-Elkins M.R., Reilly P.E.B., and Williams D.J. A global perspective on cadmium pollution and toxicity in non-occupationally exposed population. Toxicol Lett 137 (2003) 65-83
22. Satarug S., Haswell-Elkins M.R., and Moore M.R. Safe levels of cadmium intake to prevent renal toxicity in human subjects. Br J Nutr 84 (2000) 791-802
23. Schenkel HW. Nutritive Beeinflussung des Stoffwechsel verhaltens von Cadmium bei Rind und Schwein. Habilitationsschrift, Hohenheim, 1988.
24. Shiraishi N., and Waalkes M.P. Acquired tolerance to cadmium-induced toxicity in the rodent testes. Toxicol Subst Mech 15 (1996) 27-42
25. Teiichiro A., Hirmichi I., Keisuke M., Kunihiro H., and Makoto H. Cadmium-induced testicular damage in a rat model of subchronic intoxication. Reprod Med Biol 1 (2002) 59-63
26. Waalkes M.P., Rehm S., and Devor D.E. The effects of continuous testosterone exposure on spontaneous and cadmium-induced tumors in the male Fischer (F344/NCr)rat: loss of testicular response. Toxicol Appl Pharmacol 142 (1997) 40-46
27. Xu L.C., Wang S.Y., Yang X.F., and Wang X.R. Effects of cadmium on rat sperm motility evaluated with computer assisted sperm analysis. Biomol Environ Sci 14 (2001) 312
28. Zeng X., Jin T., Zhou Y., and Nordberg G.F. Changes of serum sex hormone levels and MT mRNA expression in rats orally exposed to cadmium. Toxicology 186 (2003) 109-118
29. Zylber-Haran E.A., Gershman H., Rosenmannn E., and Spitz I.M. Gonadotrophin, testosterone and prolactin interrelationships in cadmium-treated rats. J Endocrinol 92 (1982) 123-130